Could an Increased Percentage of Immature Granulocytes Accompanying Dyspepsia Predict COVID-19?Article Published on 2022-10-152022-11-15 Journal: Medicina [Category] COVID19(2023년), SARS, 치료기술, [키워드] Accompanying acute respiratory syndrome C-reactive protein coronavirus COVID-19 COVID-19 infection COVID-19 symptom CRP cut-off value determine digestive digestive symptom dyspepsia early diagnosis granulocyte immature immature granulocyte. Increased Material and Method Neutrophil-to-lymphocyte ratio NLR novel coronavirus disease parameter Patient patients pediatric Pediatric patient percentage polymerase chain positive Predictive SARS-CoV-2 SARS-CoV-2-positive patient significantly higher tested two groups typical symptom vaccination was determined were recorded [DOI] 10.3390/medicina58101460 PMC 바로가기
Long-term cellular immune response in immunocompromised unvaccinated COVID-19 patients undergoing monoclonal antibody treatmentArticle Published on 2022-10-132022-11-15 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 진단, [키워드] acute respiratory syndrome anti-SARS-CoV-2 Antigen cellular Cellular immune response cellular response clinical decision control groups Coronavirus-2 Course COVID-19 COVID-19 patient develop Effect ELISpot assay healthy control help High-risk patients immune Immunocompromised Immunocompromised patient Immunocompromised patients Immunosuppression increased risk Infection investigated mAb mAbs median monoclonal antibody monoclonal antibody treatment Patient patient cohorts SARS-CoV-2 SARS-COV-2 infection spike subject Treatment was determined [DOI] 10.3389/fimmu.2022.980698 PMC 바로가기
Surveillance, contact tracing and characteristics of SARS-CoV-2 transmission in educational settings in Northern Italy, September 2020 to April 2021Article Published on 2022-10-102022-11-16 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 변종, [키워드] Alpha variant Analysis attack rate calculated Characteristics Contact Contact tracing COVID-19 case Effectiveness elapsed identify implementation index case investigated Italy no difference occurred positive reduced remained risk of transmission SARS-CoV-2 SARS-CoV-2 transmission secondary secondary case Seven source of infection speed Spread study period surveillance data Swab test the epidemic Transmission virus was determined [DOI] 10.1371/journal.pone.0275667 PMC 바로가기
Immunogenicity, Safety, and Anti-Viral Efficacy of a Subunit SARS-CoV-2 Vaccine Candidate in Captive Black-Footed Ferrets ( Mustela nigripes) and Their Susceptibility to Viral ChallengeArticle Published on 2022-10-042022-11-15 Journal: Viruses [Category] COVID19(2023년), SARS, 진단, 치료제, [키워드] Affect Anti-viral Antibody Response Antibody titer black-footed ferrets candidate challenge clinical disease correlated declined Efficacy experimental challenge ferret highest Human immunogenicity in vitro in vivo increase in indicate lack lung viral load mice morbidity Mortality mustelids pathogen populations potential risk pre-vaccination produced Protein purified Safety SARS-CoV-2 SARS-CoV-2 S1 serum subunit susceptibility transfer Trial unlikely upper respiratory tract vaccination vaccinees viral replication was determined [DOI] 10.3390/v14102188 PMC 바로가기
Performance assessment and improvement of a care unit for COVID-19 patients with resilience engineering and motivational factors: An artificial neural network methodResearch article Published on 2022-10-012022-10-05 Journal: Computers in biology and medicine [Category] 변종, [키워드] Algorithm Analysis Artificial neural network asked Care Combination Complete COVID-19 COVID-19 patient Data envelopment analysis detrimental disease evaluate healthcare providers Healthcare system hospital Hospital staff IMPROVE indicated investigated Job satisfaction motivational factor New coronavirus performance Performance evaluation performed physical questionnaire required Resilience Resilience engineering sensitivity analysis significant increase statistical statistical test Threats was determined [DOI] 10.1016/j.compbiomed.2022.106025 [Article Type] Research article
Potential pitfalls in analysing a SARS-CoV-2 RT-PCR assay and how to standardise data interpretationSARS-CoV-2 RT-PCR 분석 및 데이터 해석을 표준화하는 방법 분석의 잠재적 함정Article Published on 2022-10-012022-09-11 Journal: Journal of virological methods [Category] COVID19(2023년), SARS, 치료기술, [키워드] addition analysed Applied Biosystem Audit automated baseline Baseline threshold carried complex data interpretation determine Diagnostics.ai Frequency implementation in some increase in Interpretation introduced investigated Laboratory manual intervention Patient PCR positive result Potential processed produced provide Real-time PCR real-time RT-PCR relative Relative threshold RT-PCR RT-PCR kit RT-PCR kits SARS-CoV-2 SARS-CoV-2 RT-PCR solution tested thermocyclers threshold time-consuming virus detection was determined [DOI] 10.1016/j.jviromet.2022.114589 PMC 바로가기 [Article Type] Article
Analytical sensitivity of the Rapid Antigen Test kits for detection of SARS-CoV-2 Omicron variant BA.2 sublineageSARS-CoV-2 Omicron 변이체 BA.2 하위 계통의 검출을 위한 Rapid Antigen Test 키트의 분석 감도Article Published on 2022-10-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus analytical sensitivity B.1.1.529 BA.2 Chain Reaction collected comparable coronavirus COVID-19 COVID-19 patient detect determined by Dilution evaluated lack limit of detection omicron polymerase chain reaction Rapid rapid antigen test reference method reverse transcription Reverse transcription-polymerase chain reaction SARS-CoV-2 selected sensitivity specimen Spread Test variant was determined was used [DOI] 10.1002/jmv.27908 PMC 바로가기 [Article Type] Article
Structural interactions of phytoconstituent(s) from cinnamon, bay leaf, oregano, and parsley with SARS-CoV-2 nucleocapsid protein: A comparative assessment for development of potential antiviral nutraceuticalsArticle Published on 2022-10-012022-11-15 Journal: Journal of food biochemistry [Category] COVID19(2023년), SARS, 진단, 치료제, [키워드] affinity Antiviral antiviral agent apigenin binding binding domain binding interaction biological activity C-terminal Cancer Cancer cells candidate carried cell line cell lines cells Cinnamomum cinnamon complex complexes components Compound computational analysis computational approach CTD cytotoxicity death drug candidate Druglikeness effective Efficacy evaluate evaluated examined greater HPLC in silico in vitro in vivo Interaction lack less molecular molecular dynamics MTT N-terminal Naturally NTD nucleocapsid nutraceutical oregano Origanum outcome parsley. plant predicted profile Prophylactic Protein provided Research responsible RNA SARS-CoV-2 SARS-CoV-2 nucleocapsid SARS-CoV-2 nucleocapsid protein stability symptomatic targets therapeutic therapeutic drug therapy Toxicity treating COVID-19 Treatment virus was determined was performed worsened [DOI] 10.1111/jfbc.14262 PMC 바로가기
Early shedding of membrane-bounded ACE2 could be an indicator for disease severity in SARS-CoV-2Article Published on 2022-10-012022-11-15 Journal: Biochimie [Category] COVID19(2023년), SARS, 바이오마커, [키워드] ACE2 Admission association Biomarker circulating Comorbidities Course COVID-19 COVID-19 patient COVID-19 patients D-dimer Diabetes Mellitus disease disease severity early phase effective ELISA healthy controls host receptor hypertension increase in Infection investigated involved marker membrane moderate outcome plasma Plasma level positive correlation sACE2 SARS-CoV-2 Severe case shown significant increase soluble ACE2 the SARS-CoV-2 was determined was obtained was performed [DOI] 10.1016/j.biochi.2022.06.005 PMC 바로가기
The Association of Baseline Plasma SARS-CoV-2 Nucleocapsid Antigen Level and Outcomes in Patients Hospitalized With COVID-19Article Published on 2022-10-012022-11-16 Journal: Annals of internal medicine [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI acute SARS-CoV-2 infection antibody Antigen baseline Biomarker body mass index Characteristics Clinical outcome clinically COVID-19 cross-sectional study delta variant discharge elevated ENhance enrolled Enrollment evaluate evaluated Factor Government greater higher odd hospital Hospital admission hospital discharge Hospitalized hospitalized patient hospitalized patients identify immunocompromising condition Infectious diseases Inpatient Laboratory less Level Logistic regression Male sex median Multiple multivariable N antigen nasal nasal swab Noninvasive ventilation Odds ratio operation outcome outcomes participant pathogenesis of COVID-19 pathogenesis of SARS-CoV-2 Patient patients with COVID-19 plasma Platform trial point-of-care polymerase chain predict quantification regression models Remdesivir renal impairment SARS-CoV-2 SARS-CoV-2 nucleocapsid severity speed Support Symptoms Therapeutics transcriptase viral replication was determined was measured were assessed worsened worsening [DOI] 10.7326/M22-0924 PMC 바로가기