Evaluating correlates of protection for mix-match vaccine against COVID-19 VOCs with potential of evading immunityArticle Published on 2022-11-082022-11-15 Journal: Vaccine [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] appear Bayesian Beta ChAdOx1 Clinical efficacy Correlate of protection COVID-19 D614G Delta Delta VOC distribution Efficacy ENhance evaluate Evaluating finding Heterologous highlight homologous Immunity inversion Mix-match mRNA-1273 neutralizing antibody omicron pandemic phase 3 trial predicted Predictive previous study provide ranged reduction reductions in strain vaccination Vaccine variant Variant of concern. variants variants of concern VoC VOCs was used while Wuhan [DOI] 10.1016/j.vaccine.2022.10.011 PMC 바로가기
Validation of SARS-CoV-2 pooled testing for surveillance using the Panther Fusion® system: Impact of pool size, automation, and assay chemistryArticle Published on 2022-11-072022-11-15 Journal: PLoS ONE [Category] SARS, 진단, 치료기술, [키워드] approach assays authorization automated conducted cut-off threshold cycle threshold decrease demonstrated diagnostic Emergency evaluated expected FDA FIVE generate Impact less limit of detection lowering nasopharyngeal sample nucleic acid amplification positive positive sample resources SARS-CoV-2 SARS-CoV-2 RNA sensitivity specificity specimen Surveillance surveillance testing System tested validation was used [DOI] 10.1371/journal.pone.0276729 PMC 바로가기
Demographic, behavioural and occupational risk factors associated with SARS-CoV-2 infection in UK healthcare workers: a retrospective observational studyArticle Published on 2022-11-072022-11-15 Journal: BMJ Open [Category] SARS, 변종, 진단, [키워드] 95% CI Analysis assessment behavioural COVID-19 demographic Diseases effective enhanced enrolled Epidemiology Factor General population HCW HCWs Health healthcare Healthcare system healthcare worker higher risk highest hospital identify include Infection infection control investigated Logistic regression measure multivariate logistic regression Observational cohort study occupational Pandemics Personal protective equipment Physiotherapist positive PPE Public public health. questionnaire Regression model Reporting Resilience retrospective risk risk factor risk reduction SARS-CoV-2 antibody SARS-COV-2 infection SARS-CoV-2 variant Selection Shrinkage social distancing social distancing measures stability sustained Vaccine variable was used Workplace [DOI] 10.1136/bmjopen-2022-063159 PMC 바로가기
Acquired Thrombotic Thrombocytopenic Purpura After BNT162b2 COVID-19 Vaccine: Case Report and Literature ReviewArticle Published on 2022-11-032022-11-15 Journal: Laboratory medicine [Category] 진단, [키워드] Acquired ADAMTS Anemia autoantibody Blood BNT162b2 BNT162b2 vaccine caplacizumab caused Complete COVID-19 COVID-19 vaccine deficiency Diagnosis gastrointestinal symptoms immunosuppressive literature microangiopathy MOST occurred outcome Patient patients Pfizer-BioNTech plasma positive Prednisone presenting report reported review second dose significantly the patient therapy thrombocytopenia thrombosis thrombotic Thrombotic thrombocytopenic purpura treated Treatment Vaccine vaccine. was used [DOI] 10.1093/labmed/lmac016 PMC 바로가기
Temporal changes in the accessory protein mutations of SARS-CoV-2 variants and their predicted structural and functional effectsArticle Published on 2022-11-012022-11-16 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, [키워드] accessory protein accessory proteins Affect amino acid sequence association bioinformatics candidate changes in contributing to correlation COVID-19 determine domains Effect Factor Frequency functional humans identify Infection Mutation mutations mutations. occur ORF6 ORF8 predicted Protein PROVEAN Q57H SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants sequence spike Spread Temporal variant variants of concern was used [DOI] 10.1002/jmv.27964 PMC 바로가기
Antiviral potential of diminazene aceturate against SARS-CoV-2 proteases using computational and in vitro approachesArticle Published on 2022-11-012022-11-15 Journal: Chemico-biological interactions [Category] SARS, 치료제, [키워드] 3D structure ACE2 addition antiparasitic approach binding binding energy caused cleavage site COVID-19 Diminazene aceturate disease drug enzyme evaluate experimental model in silico in vitro in vivo inhibit Interaction M pro membrane molecular molecular docking molecular target Prevent processed promote protease Protein Protein Data Bank PyMol reduction in S1 and S2 SARS-CoV-2 SARS-CoV-2 protease SARS-CoV-2. spike receptor-binding domain stability targets tested viral replication virus infection was used [DOI] 10.1016/j.cbi.2022.110161 PMC 바로가기
Sensor-based surveillance for digitising real-time COVID-19 tracking in the USA (DETECT): a multivariable, population-based, modelling studyArticle Published on 2022-11-012022-11-15 Journal: International Journal of Environmental Research an [Category] SARS, 치료기술, [키워드] Advancing aggregation Apple average baseline behavioural calculated Care CDC center change Cohort collected Combination Control correlation COVID-19 COVID-19 case diagnostic disease enrolled example fill out Google Fit individual information laboratory data multivariable participant participated Pearson correlation Pearson correlation coefficient physiological prevention proportion real time recruited reported Rockefeller Foundation Science seeking sensor significantly study period Surveillance symptom onset Symptoms threshold Traditional transfer USA validation cohort was used Web [DOI] 10.1016/S2589-7500(22)00156-X PMC 바로가기
Novel approach based on GQD-PHB as anchoring platform for the development of SARS-CoV-2 electrochemical immunosensorArticle Published on 2022-11-012022-11-15 Journal: Analytica chimica acta [Category] COVID19(2023년), SARS, 진단, 치료기술, 치료제, [키워드] addition analyzed antibodies antibody approach Blood carbon Carbon nanomaterial Concentration conditions coronavirus spike protein decrease develop domain Dot DPV Electrochemical devices Fever functional Graphene human serum Immunosensors construction. Interaction investigated matrix effect Modification novel PBS performed platform probe Protein provided pulse quantum RBD SARS-CoV-2 selective SEM serum shown was tested was used [DOI] 10.1016/j.aca.2022.340442 PMC 바로가기
Dispositional optimism and all-cause mortality after esophageal cancer surgery: a nationwide population-based cohort studyArticle Published on 2022-11-012022-11-15 Journal: Supportive Care in Cancer [Category] 진단, [키워드] 95% CI all-cause mortality Assessing association Cancer Cohort confounder COVID-19 COVID-19 pandemic Cox regression death esophagectomy Follow-up help IMPROVE increase in Increasing information Intervention life median occurred optimism Orientation Patient patients patients died Population population-based cohort Positive psychology postoperative predict prospective cohort study risk survival survivorship. Swedish Total tumor stage was measured was obtained was used [DOI] 10.1007/s00520-022-07311-z PMC 바로가기
Electrochemiluminescence resonance energy transfer biosensing platform between g-C3N4 nanosheet and Ru-SiO2@FA for dual-wavelength ratiometric detection of SARS-CoV-2 RdRp geneArticle Published on 2022-11-012022-11-15 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] amplification binding affinity Clinical diagnosis coronavirus Detection sensitivity disease DNA ECL Electrochemiluminescence energy transfer limit of detection multifunctional platform probe RdRp gene RdRp gene biosensor g-C(3)N(4) nanosheets. RET SARS-CoV-2 SARS-CoV-2 RdRp SARS-CoV-2 virus ssDNA syndrome target gene Treatment unique was used [DOI] 10.1016/j.bios.2022.114580 PMC 바로가기