accelerate – Page 20 – Communicable Diseases Research

Pathogenic lipid-binding antiphospholipid antibodies are associated with severity of COVID-19

병원성 지질 결합 항인지질 항체는 COVID-19의 중증도와 관련이 있습니다

Article

Published on 2021-09-012022-09-11
Journal: Journal of thrombosis and haemostasis : JTH [Category] SARS, 진단, 치료기술, 치료제,

[키워드] accelerate analyzed antibody antiphospholipid antibodies antiphospholipid antibody association Blood Blood coagulation blood coagulation disorder C-reactive protein catastrophic Cell Clinical course Clinical severity Coagulation coagulation disorder Coagulopathy Cohort complex Concentration coronavirus coronavirus disease coronavirus disease 19 COVID-19 COVID-19 patient COVID-19 patients Critical D-dimer dependent on described detectable dimer disease severity endothelial endothelial cells endothelial protein C receptor EPCR expand hallmark Hospitalized hospitalized COVID-19 patients IgG induce Infection Inflammation inflammatory effects Inflammatory response Lipid manifestation marker median Microvascular thrombosis monocyte Monocytes Mortality outcome pathogenic Patient poor prognosis producing Protein protein C prothrombotic prothrombotic syndrome receptor respiratory secreting Severe acute respiratory syndrome severity of COVID-19 signaling pathway single center stroke syndrome thrombosis thrombotic Thrombus thrombus formation venous
[DOI] 10.1111/jth.15455 PMC 바로가기 [Article Type] Article

The structural basis of accelerated host cell entry by SARS-CoV-2†

SARS-CoV-2에 의한 가속화된 숙주 세포 진입의 구조적 기초†

Article

Published on 2021-09-012022-09-11
Journal: The Febs Journal [Category] MERS, SARS, 진단, 치료기술, 치료제,

[키워드] accelerate accelerated ACE-2 ACE2-RBD acute respiratory syndrome acute respiratory syndrome coronavirus angiotensin Angiotensin-converting enzyme Antiviral strategies antiviral strategy base C-terminal domain causative agent cell entry cellular entry cleavage site conserved Contact contagious contribute coronavirus Coronavirus disease 2019 COVID-19 disease domain effective entry receptor enzyme epithelial epithelium exhibit explain faster Features flat furin furin protease HCoVs high-affinity binding host cell human coronavirus hypothese Interaction leads Mutation N-terminal domain notable NTD other proteases pandemic pandemic coronavirus Proteases Protein protein-protein interaction RBD receptor Receptor-binding domain respiratory respiratory epithelia S protein S1 subunit SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 sialic acid sialic acid-binding domain. Spike protein subunit the receptor-binding domain the S protein the S1 subunit the spike protein Tight binding turn Viral viral RBD viral S viral spike
[DOI] 10.1111/febs.15651 PMC 바로가기 [Article Type] Article

Recovery of a patient with severe COVID-19 by acupuncture and Chinese herbal medicine adjuvant to standard care

침술 및 중국 약초 보조제에 의한 심각한 코비드 -19 환자의 회복 표준 치료

Case Reports

Published on 2021-09-012022-08-31
Journal: Journal of integrative medicine [Category] MERS, 치료제,

[키워드] Absorption accelerate acupuncture addition adjuvant adjuvants breath breathing function C-reactive protein Case report Chest computed tomography Chinese Chinese herbal medicine Combination Computed tomography contagious coronavirus disease Coronavirus disease 2019 COVID-19 CRP decrease dosage effective therapy female heart rate herbal medicine Integrative therapy lesion life-threatening Lung infection lymphocyte MLR monocyte neutrophil NLR Older oxygen Patient peripheral oxygen saturation rescue seeking Severe case Severe case. severe cases severe COVID-19 Shortness of breath significantly standard care the patient therapy treated was increased Wuhan Wuhan, China
[DOI] 10.1016/j.joim.2021.06.001 PMC 바로가기 [Article Type] Case Reports

Mechanical activation of spike fosters SARS-CoV-2 viral infection

스파이크의 기계적 활성화는 SARS-CoV-2 바이러스 감염을 촉진합니다

Article

Published on 2021-08-312022-09-11
Journal: Cell Research [Category] MERS, SARS, 변종, 진단,

Knowledge Graph-Based Approaches to Drug Repurposing for COVID-19

COVID-19에 대한 약물 용도 변경에 대한 지식 그래프 기반 접근 방식

Article

Published on 2021-08-232022-09-11
Journal: Journal of Chemical Information and Modeling [Category] MERS, SARS, 신약개발, 치료제,

A critical overview of computational approaches employed for COVID-19 drug discovery

COVID-19 약물 발견에 사용되는 컴퓨터 접근 방식에 대한 중요한 개요

Review

Published on 2021-08-212022-09-11
Journal: Chemical Society reviews [Category] MERS, SARS, 신약개발, 임상, 치료제,

Diagnostic testing holds the key to NTD elimination

Viewpoints

Published on 2021-08-192022-10-28
Journal: PLoS Neglected Tropical Diseases [Category] Coronavirus, MERS, SARS,

[키워드] accelerate ambition COVID-19 diagnostic diagnostic test diagnostic testing diagnostics disease Diseases duplication ecosystem effort lack NTD NTDs pandemic resources target tropical viability WHO World Health Organization’
[DOI] 10.1371/journal.pntd.0009626 PMC 바로가기 [Article Type] Viewpoints

Prioritizing ‘equity’ in COVID-19 vaccine distribution through Global Health Diplomacy

Perspective

Published on 2021-08-182022-10-31
Journal: Health Promotion Perspectives [Category] COVID-19,

Sargramostim (rhu GM-CSF) as Cancer Therapy (Systematic Review) and An Immunomodulator. A Drug Before Its Time?

Immunology

Published on 2021-08-172022-11-01
Journal: Frontiers in Immunology [Category] Coronavirus, MERS, SARS,

[키워드] accelerate accelerated acute respiratory distress Adaptive immune response adaptive immune system anti-cancer response approved ARDS Autoimmune biological activity Bone marrow bone marrow failure Cancer Clinical data clinical setting clinical settings COVID-19 database Diseases drug Efficacy ENhance Essential example FDA GM-CSF granulocyte-macrophage colony-stimulating factor hematologic host immunity humans immune Immune checkpoint inhibitor immune modulation Immune suppression immune therapy Immunotherapy Infection infections innate immune response less modulating monoclonal antibodies objective Other Pulmonary alveolar proteinosis reported Result resulting review safety profile sargramostim Sepsis significantly solid cancer survival syndrome Therapies therapy tissue repair Toxicity trauma US FDA Vaccine variety
[DOI] 10.3389/fimmu.2021.706186 PMC 바로가기 [Article Type] Immunology

The COVIDome Explorer researcher portal

COVIDome Explorer 연구원 포털

Article

Published on 2021-08-172022-09-11
Journal: Cell Reports [Category] MERS, 유전자 메커니즘, 진단,

[키워드] accelerate Analysis analyzed association Blood blood cell C-reactive protein Cell cellular Clinical data complementary COVID-19 COVID-19 research CRP CRP level CRP levels cytokine Cytometry damage Damage-associated molecular patterns data portal dataset Depletion dysregulation hospitalized COVID-19 patients Hypothesis Hypothesis testing immune Immune cell immune system Infection Inflammation marker metabolism metabolomics mitochondrial mitochondrial metabolism molecular Multi-omics multidimensional pathology physiological plasma plasma proteomics poor prognosis portal Protective real time red blood cell researcher SARS serpins serpins. Transcriptome
[DOI] 10.1016/j.celrep.2021.109527 PMC 바로가기 [Article Type] Article