Antibody responses – Page 20 – Communicable Diseases Research

High-throughput detection of antibodies targeting the SARS-CoV-2 Spike in longitudinal convalescent plasma samples

종적 회복기 혈장 샘플에서 SARS-CoV-2 스파이크를 표적으로 하는 항체의 고처리량 검출

Clinical Trial

Published on 2021-05-012022-09-11
Journal: Transfusion [Category] MERS, SARS, 임상, 진단, 치료기술, 치료제,

Longevity of Middle East Respiratory Syndrome Coronavirus Antibody Responses in Humans, Saudi Arabia

Dispatch

Published on 2021-05-012022-10-31
Journal: Emerging Infectious Diseases [Category] Coronavirus,

Serological surveillance of SARS-CoV-2: Six-month trends and antibody response in a cohort of public health workers

SARS-CoV-2의 혈청학적 감시: 공중 보건 종사자 집단의 6개월 추세 및 항체 반응

Article

Published on 2021-05-012022-09-11
Journal: The Journal of Infection [Category] Fulltext, SARS, 진단, 치료기술,

[키워드] Abbott antibody Antibody Response Antibody responses assays changed clinical Cohort Course credible interval Critical declined dependent on domain Effect England English Euroimmun FIVE healthcare worker healthy Immunity immunoassays individual Infection large cohort MOST natural infection nucleoprotein occurred positive positive individuals progression proportion Protein public health RBD recruited reduction in Region remained response Roche SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-COV-2 infection SARS-CoV-2 spike Seroconversion seropositive Surveillance tested the epidemic threshold trend vaccination
[DOI] 10.1016/j.jinf.2021.03.015 PMC 바로가기 [Article Type] Article

From Multiplex Serology to Serolomics—A Novel Approach to the Antibody Response against the SARS-CoV-2 Proteome

다중 혈청학에서 혈청학으로 - SARS-CoV-2 단백질체에 대한 항체 반응에 대한 새로운 접근

Article

Published on 2021-04-242022-09-01
Journal: Viruses [Category] MERS, SARS, 진단, 치료기술, 치료법,

[키워드] age Algorithm Analysis Antibody Response Antibody responses assays ccCoVs Cohort common cold common cold Coronaviruses Control Course COVID-19 case COVID-19 patient determine Disease progression dual E. coli ELISA enzyme-linked immunosorbent expressed fluorescent HEK293 cells hospitalized patient Ig isotype Ig isotypes immunofluorescence Immunoglobulin multiplex serology novel pathogen Pathogens Protein proteome Receptor-binding domain Research question response SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 epidemiology SARS-CoV-2 N SARS-CoV-2 pandemic SARS-CoV-2 protein SARS-CoV-2 proteins SARS-CoV-2 proteome SARS-CoV-2 research sensitivity Sensitivity and specificity Serological assay serological assays specificity Spike protein symptom onset the receptor-binding domain the SARS-CoV-2 the spike protein
[DOI] 10.3390/v13050749 PMC 바로가기 [Article Type] Article

Immune Profiling to Determine Early Disease Trajectories Associated With Coronavirus Disease 2019 Mortality Rate: A Substudy from the ACTT-1 Trial

코로나바이러스 질병 2019 사망률과 관련된 조기 질병 궤적을 결정하기 위한 면역 프로파일링: ACTT-1 시험의 하위 연구

Article

Published on 2021-04-232022-09-11
Journal: The Journal of Infectious Diseases [Category] MERS, SARS, 진단, 치료제,

[키워드] ACTT-1 acute respiratory syndrome acute respiratory syndrome coronavirus 2 affected antibody Antibody Response Antibody responses antiviral therapy Clustering coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cytokine cytokine response death disease trajectories dominant early disease enrolled Hierarchical hierarchical clustering Hospitalized Host immune response host immune responses immune responses investigated neutralization occurred outcome participant Placebo Profiling Randomized Remdesivir respiratory serology seronegative serum severe acute respiratory syndrome Coronavirus specimen study enrollment study participant symptom onset trajectory Treatment with COVID-19
[DOI] 10.1093/infdis/jiab035 PMC 바로가기 [Article Type] Article

Rapid decline of neutralizing antibodies is associated with decay of IgM in adults recovered from mild COVID-19

중화 항체의 급격한 감소는 가벼운 COVID-19에서 회복된 성인의 IgM 붕괴와 관련이 있습니다

Article

Published on 2021-04-202022-09-11
Journal: Cell Reports Medicine [Category] MERS, SARS, 진단, 치료법,

[키워드] age anti-RBD anti-receptor-binding domain anti-S antibody Antibody avidity Antibody Response Antibody responses avidity binding Cohort COVID-19 Decline declines defined Fever Follow-up functional Gender IgA IgG IgM Immunoglobulin immunoglobulin A implication increase Infection levels of antibodies Mild mild infection mild SARS-CoV-2 infection Neutralizing antibodies neutralizing antibody Neutralizing antibody response neutralizing antibody responses observation observé participant protective immunity Protein Rapid RBD respiratory responses SARS-CoV-2 SARS-COV-2 infection symptom onset trimer Viral Viral antigen viral antigens
[DOI] 10.1016/j.xcrm.2021.100253 PMC 바로가기 [Article Type] Article

Long-term persistence of RBD + memory B cells encoding neutralizing antibodies in SARS-CoV-2 infection

SARS-CoV-2 감염에서 중화 항체를 암호화하는 RBD + 기억 B 세포의 장기 지속성

Article

Published on 2021-04-202022-09-11
Journal: Cell Reports Medicine [Category] MERS, SARS, 진단, 치료기술,

[키워드] Antibody responses Antibody titer Antibody titers Cell Cohort COSIN COVID declining detectable domain Evidence evidence of functional functional MBCs generate Infection longitudinal tracking maintenance MBCs memory B memory B cell memory B cells MONITOR monoclonal antibodies monoclonal antibody Neutralizing antibodies neutralizing antibody neutralizing capacity neutralizing response Participants persistence plasma protective immunity RBD RBD tetramer Reinfection respiratory SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pseudovirus selected Severe acute respiratory syndrome severe acute respiratory syndrome-coronavirus-2 subset the antibody response while
[DOI] 10.1016/j.xcrm.2021.100228 PMC 바로가기 [Article Type] Article

Reduced neutralization of SARS-CoV-2 B.1.1.7 variant by convalescent and vaccine sera

회복기 및 백신 혈청에 의한 SARS-CoV-2 B.1.1.7 변이체의 중화 감소

Article

Published on 2021-04-152022-09-11
Journal: Cell [Category] MERS, SARS, 변종, 진단,

[키워드] Abstract ACE2 ACE2 binding Amino acid amino acid change Analysis antibody Antibody Response Antibody responses appearance B.1.1.7 B.1.1.7 variant binding affinity can not caused Contact convalescent death dominant elicited ENhance escape evade generate IGHV3-53 Kent monoclonal antibodies monoclonal antibody mutant virus mutant viruses N501Y natural antibody natural infection neutralization neutralize neutralized original original form pandemic parental reduced residue responses responses against SARS-CoV-2 SARS-CoV-2 B.1.1.7 SARS-COV-2 infection sera Transmission vaccination Vaccine Vaccines variant virus virus replication Virus spike viruses widespread
[DOI] 10.1016/j.cell.2021.02.033 PMC 바로가기 [Article Type] Article

IgG and IgM antibody formation to spike and nucleocapsid proteins in COVID-19 characterized by multiplex immunoblot assays

다중 면역블롯 분석을 특징으로 하는 COVID-19에서 스파이크 및 뉴클레오캡시드 단백질에 대한 IgG 및 IgM 항체 형성

Research Article

Published on 2021-04-072022-09-01
Journal: BMC Infectious Diseases [Category] MERS, 진단, 치료법, 치료제,

[키워드] allergy antibody antibody formation Antibody Response Antibody responses Antigen Antisera assays autoimmune condition autoimmune conditions caused characterized COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients criteria detection diagnostic tests Diseases IgG IgG and IgM IgM IgM antibodies IgM antibody immunoblot Influenza Laboratory less Line immunoblot assay mild symptoms multiplex Multiplex assay N proteins nucleocapsid protein offer performed plateau positive Positive test proportion proportions Proteins qPCR test Rapid RBD Receptor binding domain Receptor-binding domain recombinant Recombinant nucleocapsid protein recommendation Result RT-qPCR RT-qPCR test SARS-CoV-2 SARS-CoV-2 protein SARS-CoV-2 proteins SARS-CoV-2 virus SARS-CoV-2 virus protein SARS-CoV-2 virus proteins sensitivity sera Seroconversion serological Serological assay Serological diagnosis Specificities specificity Spike protein spike protein of SARS-CoV-2 supplementary material the spike protein Viral viral infections were used
[DOI] 10.1186/s12879-021-06031-9 PMC 바로가기 [Article Type] Research Article

Distinct SARS-CoV-2 antibody reactivity patterns in coronavirus convalescent plasma revealed by a coronavirus antigen microarray

코로나바이러스 항원 마이크로어레이로 밝혀진 코로나바이러스 회복기 혈장의 뚜렷한 SARS-CoV-2 항체 반응성 패턴

Article

Published on 2021-04-062022-09-01
Journal: Scientific Reports [Category] MERS, SARS, 진단,

[키워드] acute COVID-19 Adaptive immunity administration analyses Analysis analyzed antibody reactivity Antibody Response Antibody responses Antigen antigens array assays CCP chemiluminescence immunoassay clinical Clinical studies Cluster Clustering analysis collected Computational approaches Concordance convalescent plasma coronavirus COVID-19 case COVID-19 cases COVID-19 convalescent plasma Cutoff disease Donor Emergency use EUA FDA Generalized linear model Hierarchical Hierarchical clustering analysis Humoral immunity identify immunoassay Immunoglobulin IMPROVE Infection intensity MERS Microarray multiplex neutralization Neutralization assay offer plasma plasma sample plasma samples positive Predictive pseudovirus random Random forest reactive reactivity reactivity pattern recombinant proteins reporter Result SARS-1 SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 antigen SARS-CoV-2 antigens SARS-COV-2 infection SARS-CoV2 serum specimen the SARS-CoV-2 therapeutic efficacy threshold thresholds Total total Ig training set Treatment vaccination vaccine immunogenicity Viral viral particle was used with COVID-19
[DOI] 10.1038/s41598-021-87137-7 PMC 바로가기 [Article Type] Article