The Unyvero Hospital-Acquired pneumonia panel for diagnosis of secondary bacterial pneumonia in COVID-19 patients유니베로병원 획득 폐렴 패널, 코로나19 환자 2차 세균성 폐렴 진단Original Article Published on 2021-03-042022-09-10 Journal: European Journal of Clinical Microbiology & Infect [Category] SARS, 치료기술, [키워드] 95% CI 95%CI application bacterial pathogen Bacterial pathogens bacterial pneumonia bacterial species bacterial specy carried Concordance COVID-19 COVID-19 patient Critically ill critically ill COVID-19 patients Culture demonstrated Diagnosis diagnostic evaluate Hospital-Acquired pneumonia HPN Lower respiratory tract LRT multiplex Multiplex PCR Multiplex-PCR Negative predictive value Pathogens PCR-based method performance Pneumonia positive predictive values Rapid-diagnostic tests reference method residual respiratory secondary bacterial pneumonia sensitivity SOC specificity Standard-of-care supplementary material tested were used [DOI] 10.1007/s10096-021-04194-6 PMC 바로가기 [Article Type] Original Article
Phenotypes and Subphenotypes of Patients With COVID-19: A Latent Class Modeling AnalysisResearch article Published on 2021-02-262022-10-05 Journal: Chest [Category] 바이오마커, [키워드] Analysis analyzed assist association Basic science Biomarker Blood class Cleveland clinic Clinical outcome clinical trial clinical trials Cluster Comorbidities Concordance COVID-19 COVID-19 phenotype COVID-19 symptom database death demographics elevated evaluated help heterogeneity hospital Hospital admission Hospitalization hospitalized patient hospitalized patients Hyperinflammatory ICU identifying independent investigated investigator kidney dysfunction laboratory-confirmed SARS-CoV-2 infection Latent latent class latent class analysis lymphopenic modeling Mortality Patient patients patients with COVID-19 phenotype Phenotypes phenotypic Platelet positive predict presenting presenting symptoms profile Research researcher Result significantly stratified subphenotypes Symptoms System transfer translational WBC [DOI] 10.1016/j.chest.2021.01.057 [Article Type] Research article
Performance of SARS-CoV-2 serology tests: Are they good enough?SARS-CoV-2 혈청학 테스트의 성능: 충분히 좋은가요?Research Article Published on 2021-02-172022-09-10 Journal: PLoS ONE [Category] MERS, 진단, 치료기술, 치료법, [키워드] Abbott Abbott Diagnostics Analysis analyzed Antibody detection Clinical practice Community Complete Concordance condition controls cross-reactive demonstrated diagnostic diagnostic sensitivity diagnostic specificity DiaSorin effort Emergency epitope Euroimmun evaluated False negative false negative result head Healgen IgG Immunoglobulin Inflammatory introduced nucleocapsid organizations pandemic Patient PCR performance point of care polyarthritis positive ranged Rapid test Regulatory required respiratory respiratory infection respiratory infections SARS-CoV-2 SARS-CoV-2 pandemic Sensitivity and specificity serologic assay serological test Serological tests serology serology testing specificity specimen Spike proteins tested the SARS-CoV-2 Thyroid thyroid stimulating immunoglobulin [DOI] 10.1371/journal.pone.0245914 PMC 바로가기 [Article Type] Research Article
High throughput detection and genetic epidemiology of SARS-CoV-2 using COVIDSeq next-generation sequencingCOVIDSeq 차세대 시퀀싱을 사용한 SARS-CoV-2의 고처리량 검출 및 유전 역학Research Article Published on 2021-02-172022-08-13 Journal: PLoS ONE [Category] MERS, 변종, 유전자 메커니즘, 치료기술, [키워드] added affecting Analysis approach approaches B.1.112 B.1.99 best clades clinical sample Concordance coronavirus disease Coronavirus disease 2019 COVID-19 COVIDSeq COVIDSeq approach COVIDSeq protocol detect Diagnosis duplicate duplicates Epidemiology Evolution flow cell Genetic Genetic epidemiology global pandemic in-depth analysis Inconclusive India individual knowledge Lineage Multiplex-PCR Next-generation sequencing NovaSeq 6000 nucleotide positive RT-PCR SARS-CoV-2 sensitivity sequenced Sequencing sequencing approach Single nucleotide variant Surveillance the SARS-CoV-2 unique variant [DOI] 10.1371/journal.pone.0247115 PMC 바로가기 [Article Type] Research Article
Comparison of Severe Acute Respiratory Syndrome Coronavirus 2 Screening Using Reverse Transcriptase–Quantitative Polymerase Chain Reaction or CRISPR-Based Assays in Asymptomatic College Students무증상 대학생에서 역전사효소-정량적 중합효소 연쇄 반응 또는 CRISPR 기반 분석을 사용한 중증 급성 호흡기 증후군 코로나바이러스 2 선별 검사의 비교Comparative Study Published on 2021-02-112022-09-10 Journal: JAMA Network Open [Category] MERS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age approach assays Asymptomatic Asymptomatic case capture chain Chain Reaction clinical clinical laboratory clinical samples Cohort cohort study collected college Community Concordance Containment coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 covert COVID-19 CREST CRISPR determine diagnostic diagnostic testing effective evaluated exposure female finding highlighting Importance improvement in viral individual information Laboratory leading edge Local lockdown measure Measures Metrics Mitigation objective offer oropharyngeal swab outbreak Outbreaks pandemic participant Point polymerase chain polymerase chain reaction positive positive result positive sample Prevalence public health qPCR reaction Relaxation Relevance reopening required respiratory Result reverse transcriptase rising RT-qPCR SARS-CoV-2 SARS-CoV-2 testing screened Screening setting severe acute respiratory syndrome Coronavirus shift student study participant Study participants surveillance testing test results Testing universities Viral Viral load viral loads Viral transmission virus virus detection [DOI] 10.1001/jamanetworkopen.2020.37129 PMC 바로가기 [Article Type] Comparative Study
Limited Secondary Transmission of the Novel Coronavirus (SARS-CoV-2) by Asymptomatic and Mild COVID-19 Patients in BhutanArticles Published on 2021-02-102022-10-28 Journal: The American Journal of Tropical Medicine and Hygi [Category] COVID-19, MERS, SARS, [키워드] age Asymptomatic Concordance confirmed cases confirmed COVID-19 case Contact country COVID-19 COVID-19 pandemic COVID-19 patient females individual Limited mandatory mild case mild COVID-19 patient novel occurred Patient quarantine SARS-CoV-2 secondary secondary transmission Seven Symptom the disease Transmissibility transmissibility of SARS-CoV-2 Transmission virus [DOI] 10.4269/ajtmh.20-0672 PMC 바로가기 [Article Type] Articles
Rapid electrochemical detection of coronavirus SARS-CoV-2코로나바이러스 SARS-CoV-2의 신속한 전기화학적 검출Article Published on 2021-02-052022-09-10 Journal: Nature Communications [Category] MERS, 변종, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Amplicon caused clinical samples Complete Concordance contagious contagious disease coronavirus coronavirus disease Coronavirus disease 2019 coronavirus SARS-CoV-2 correlation COVID-19 COVID-19 diagnosis detect detectable diagnostic diagnostic test disease Genes hybridization isothermal less Oligonucleotide probes Other respiratory viruses positive probe probes qRT-PCR quantitation Quantitative Rapid RCA respiratory respiratory viruses reverse transcription PCR Rolling circle amplification SARS-CoV-2 sensor sensors severe acute respiratory syndrome Coronavirus time-consuming [DOI] 10.1038/s41467-021-21121-7 PMC 바로가기 [Article Type] Article
Insights from Patterns of SARS-CoV-2 Immunoglobulin G Serology Test Results from a National Clinical Laboratory, United States, March–July 20202020년 3~7월 미국 국립 임상 연구소의 SARS-CoV-2 면역글로불린 G 혈청학 검사 결과 패턴의 통찰력Original Articles Published on 2021-02-012022-09-01 Journal: Population Health Management [Category] MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 age Analysis analyzed children clinical Concordance Coronavirus-2 COVID-19 declined detectable develop Factor groups household identify IgG IgG antibody IgG positivity immune response Immunoglobulin Immunoglobulin G in some include individual infecting Infection information initiated insight Laboratory less Loss NAAT National nucleic acid nucleic acid amplification nucleic acid amplification testing Patient patients pattern persistence positive Probability proportion respiratory Result SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 RNA serologic test serologic tests serology serology testing Seropositivity Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 Sex Test tested the United State United States were used [DOI] 10.1089/pop.2020.0256 PMC 바로가기 [Article Type] Original Articles
Practical challenges to the clinical implementation of saliva for SARS-CoV-2 detectionSARS-CoV-2 검출을 위한 타액의 임상 구현에 대한 실제적인 도전Article Published on 2021-02-012022-09-11 Journal: European Journal of Clinical Microbiology & Infect [Category] SARS, 치료기술, [키워드] Accuracy Care collected Concordance conditions COVID-19 COVID-19 pandemic demonstrated diagnostic evaluated feasibility human saliva implementation initial Long-term care media nasopharyngeal Nasopharyngeal swab nasopharyngeal swabs outbreak room temperature Saliva saliva samples SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 RNA specimen specimen collection temperature Transport transported Viral viral transport media [DOI] 10.1007/s10096-020-04090-5 PMC 바로가기 [Article Type] Article
Detection of SARS-CoV-2 from patient fecal samples by whole genome sequencingResearch Published on 2021-01-302022-11-01 Journal: Gut Pathogens [Category] COVID-19, [키워드] Analysis Complete Concordance coronavirus COVID-19 COVID-19 patients detection Fecal sample fecal samples Fecal–oral transmission Fecal–oral transmission highlight identify methodology Mutation nasopharyngeal Next-generation sequencing NGS participant Patient patients Result RT-PCR RT-PCR nasopharyngeal swab SARS-CoV-2 SARS-CoV-2 detection Sequencing Stool variant Variation viability whole genome [DOI] 10.1186/s13099-021-00398-5 PMC 바로가기 [Article Type] Research