conditions – Page 20 – Communicable Diseases Research

Virtual Screening of Natural Chemical Databases to Search for Potential ACE2 Inhibitors

Article

Published on 2022-03-072022-10-30
Journal: Molecules [Category] COVID-19,

SARS-CoV-2 Spike Protein 1 Activates Microvascular Endothelial Cells and Complement System Leading to Platelet Aggregation

SARS-CoV-2 스파이크 단백질 1은 미세혈관 내피 세포 및 보체 시스템을 활성화하여 혈소판 응집을 유도합니다

Article

Published on 2022-03-072022-09-11
Journal: Frontiers in Immunology [Category] SARS, 치료기술,

[키워드] ACE2 Activation addition adhesive molecule aggregate aggregation AMPK amplified Analysis angiotensin angiotensin converting enzyme angiotensin converting enzyme 2 antibody blockade blocking antibody Blot C3a C5a circulating complement Complement activation complement inhibitors complement system complexity conditions coronavirus disease Coronavirus disease 2019 COVID-19 detection element ELISA endothelial Endothelial cell endothelial cells endothelial damage Endothelial dysfunction enzyme evaluated Exocytosis experiment expression human host immunofluorescence incubated induce infect Inflammation Inflammatory inhibitors investigated leading leukocyte lung Microvascular thrombosis microvasculature Mortality multiorgan failure P-selectin performed phenotype Platelet platelet aggregation pro-inflammatory recruitment replicate robust S1 protein SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 spike protein 1 selectin sera severe COVID-19 patient severe COVID-19 patients significant level spike Spike protein System thromboembolic thromboembolic complication thromboembolic complications thrombomodulin thrombosis thrombotic thrombotic complication Thrombotic complications viral infection von Willebrand factor were assessed western blot Western blot analysis
[DOI] 10.3389/fimmu.2022.827146 PMC 바로가기 [Article Type] Article

Positive Effects of an Online Workplace Exercise Intervention during the COVID-19 Pandemic on Quality of Life Perception in Computer Workers: A Quasi-Experimental Study Design

Article

Published on 2022-03-072022-10-29
Journal: International Journal of Environmental Research an [Category] Coronavirus, MERS, SARS,

Disinfection efficiency test for contaminated surgical mask by using Ozone generator

Research

Published on 2022-03-072022-10-28
Journal: BMC Infectious Diseases [Category] Coronavirus, MERS, SARS,

Students’ negative emotions and their rational and irrational behaviors during COVID-19 outbreak

Research Article

Published on 2022-03-072022-10-28
Journal: PLoS ONE [Category] Coronavirus, MERS, SARS,

[키워드] activity addition Adults age analyzed asked BMI body mass index conditions conducted COVID-19 COVID-19 outbreak demographic characteristics detrimental effect effort enrolled event Evidence extreme Factor Gender Health mental health negative emotion negative emotions pandemic question significant difference Spread Stress virus
[DOI] 10.1371/journal.pone.0264985 PMC 바로가기 [Article Type] Research Article

Outlook of therapeutic and diagnostic competency of nanobodies against SARS-CoV-2: A systematic review

SARS-CoV-2에 대한 나노바디의 치료 및 진단 역량 전망: 체계적인 검토

Article

Published on 2022-03-012022-09-11
Journal: Analytical biochemistry [Category] SARS, 치료기술,

Genotype-phenotype correlation identified a novel SARS-CoV-2 variant possibly linked to severe disease

유전형-표현형 상관관계가 심각한 질병과 관련될 수 있는 새로운 SARS-CoV-2 변이를 확인했습니다

Article

Published on 2022-03-012022-09-11
Journal: Transboundary and emerging diseases [Category] MERS, SARS, 변종, 진단,

[키워드] Adults age analysed Asia carried Clinical data Cluster Clustering conditions correlation COVID-19 COVID-19 patient D614G mutation database Diabetic diabetic patient diabetic patients disease severity Dubai Europe European Evidence First wave Fisher Fisher's exact test genomes geographic location Health healthy heterogeneous higher infectivity highlight hospital Hospital admission Hospitalized ICU independent India intensive care Iran laboratory-confirmed majority medical record medical records Mild Missense moderate disease molecular Molecular epidemiology molecular phylogeny Mortality Mutation N proteins Nasopharyngeal swab nasopharyngeal swab PCR nasopharyngeal swabs obese Older age outbreak overweight overweight/obese Patient positive Q271R SARS-CoV-2 SARS-CoV-2 genome sequence SARS-CoV-2 genome sequences SARS-CoV-2 variant selected sequenced Sequencing sequencing data severe COVID-19 severe disease Sex significantly strain synonymous Test Transmission unique United Arab Emirates Viral viral strain viral strains whole genome Whole genome sequencing women
[DOI] 10.1111/tbed.14004 PMC 바로가기 [Article Type] Article

Blocking TNF signaling may save lives in COVID-19 infection

TNF 신호를 차단하면 COVID-19 감염에서 생명을 구할 수 있습니다

Review

Published on 2022-03-012022-09-11
Journal: Molecular biology reports [Category] SARS, 바이오마커, 신약개발,

[키워드] activated Activation anti-TNF binding blocking Blood blood clotting burst cascades clinical trials conditions consequence COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 patient COVID-19 patients cytokine Cytokine storm Cytokines death downstream drug effort Evidence Factor heart failure high mortality Hope IFNγ IL-6 immune therapy insulin insulin resistance involved kinase kinases lung damage mechanism mediator Medicine monoclonal antibodies monoclonal antibody multiple organ failure NFkappaB NFkB Organ failure Other other conditions pathogenic Prevent pro-inflammatory cytokine pro-inflammatory cytokines provided receptor resulting selected Severe case severe cases the disease therapy TNF TNF signaling Treatment strategies treatment strategy Tumor tumor necrosis tumor necrosis factor Tumor Necrosis Factor (TNF). vaccination
[DOI] 10.1007/s11033-022-07166-x PMC 바로가기 [Article Type] Review

Comparative study of SARS-CoV-2 infection in different cell types: Biophysical-computational approach to the role of potential receptors

다양한 세포 유형에서 SARS-CoV-2 감염에 대한 비교 연구: 잠재적 수용체의 역할에 대한 생물물리학적 전산적 접근

Article

Published on 2022-03-012022-09-12
Journal: Computers in biology and medicine [Category] MERS, SARS, 진단,

[키워드] A549 ACE2 addition AGTR2 angiotensin-converting enzyme 2 approach CD147 Cell cell line cell lines Cell susceptibility cellular Comparative conditions dependent on docking early infection expected experiment expression expression level expression levels greater Heat shock HEK293 HepG2 Host host protein HSPA5 Infection Interaction kinetic less Lungs macromolecular Macromolecular crowding membrane NRP1 NTERA-2 parameter predict predicted promote protease Protein Quantitative receptor receptors Research respiratory tract SARS CoV-2 SARS-COV-2 infection serine 2 stimulate susceptibility TMPRSS2 transcriptomic data transmembrane viral dynamics viral growth viral spike Viral spike. virus
[DOI] 10.1016/j.compbiomed.2022.105245 PMC 바로가기 [Article Type] Article

Racial and ethnic disparities in cardiometabolic disease and COVID-19 outcomes in White, Black/African American, and Latinx populations: Physiological underpinnings

Review article

Published on 2022-03-012022-10-05
Journal: Progress in Cardiovascular Diseases [Category] SARS, 바이오마커,