D614G – Page 20 – Communicable Diseases Research

SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion

Article

Published on 2021-09-062022-10-30
Journal: Nature [Category] COVID-19, Fulltext, SARS,

Genomic analysis of early transmissibility assessment of the D614G mutant strain of SARS-CoV-2 in travelers returning to Taiwan from the United States of America

Microbiology

Published on 2021-09-022022-10-28
Journal: PeerJ [Category] COVID-19,

[키워드] acute respiratory syndrome America Analysis characterized circulation Cluster Comparative Continuous coronavirus COVID-19 D614G D614G mutation determine Direct epidemiological Evolution FIVE Genetic variation Genome genome sequence genomic genomic data GISAID global pandemic highlight imported case Infection isolate isolates mutant network analysis Outbreaks performed Phylogenetic analysis Result returned risk RT-PCR SARS-CoV-2 SARS-CoV-2 variant separated single-nucleotide specimen Surveillance Taiwan the SARS-CoV-2 genome the United State trajectory Transmissibility Transmission Travel USA Variation viral pathogenicity virus virus strain was performed whole-genome sequencing
[DOI] 10.7717/peerj.11991 PMC 바로가기 [Article Type] Microbiology

Targeting SARS-CoV-2 receptor-binding domain to cells expressing CD40 improves protection to infection in convalescent macaques

CD40을 발현하는 세포에 대한 SARS-COV-2 수용체-결합 도메인을 표적으로하는 것은 회복기 원숭이의 감염에 대한 보호를 향상시킨다.

Article

Published on 2021-09-012022-08-31
Journal: Nature Communications [Category] SARS, 바이오마커, 변종, 유전자 메커니즘,

[키워드] adjuvant animal models antibody antigen-presenting cells approach approved B cells B1.351 boost CD40 Cell children convalescent Coverage cross-neutralize D614G domain expressing High-dose humanized IMPROVE individuals induce Infection injected long-term memory macaque Marlin memory mRNA vaccines Neutralizing antibodies neutralizing antibody NHPs non-human primate Phenotypes Preclinical research pregnant women Protein vaccines rapid increase RBD Receptor-binding domain SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 variants significant level significantly single dose Spike protein Subunit vaccine subunit vaccines T and B cells targeting the receptor-binding domain the SARS-CoV-2 vaccination Vaccine Viral Viral antigen viral antigens viral infection Viral vector viral vector and mRNA vaccines virulent
[DOI] 10.1038/s41467-021-25382-0 PMC 바로가기 [Article Type] Article

SARS-CoV-2 Spike Protein Mutations and Escape from Antibodies: A Computational Model of Epitope Loss in Variants of Concern

SARS-CoV-2 스파이크 단백질 돌연변이 및 항체 탈출: 우려되는 변이체에서 에피토프 손실의 계산 모델

Article

Published on 2021-09-012022-09-10
Journal: Journal of Chemical Information and Modeling [Category] SARS, 변종, 진단,

[키워드] antibody Antibody binding antibody binding sites applied changes in characterized concern consequence Contact COVID-19 vaccines D614G develop dominant Efficacy elicited epitope Epitopes escape evade glycosylated helping Host immunogenic immunological immunoreactivity Loss Model Modification modifications molecular molecular dynamics mutant mutants Mutation performed predict Protein raise reactivity Recognition recognize reduce Region regions S-protein S-protein variant SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 spike variants sequence solution spike Structure translate Treatment Vaccine vaccine efficacy Vaccines variant variants Viral viral surface virus while
[DOI] 10.1021/acs.jcim.1c00857 PMC 바로가기 [Article Type] Article

Global variation in SARS-CoV-2 proteome and its implication in pre-lockdown emergence and dissemination of 5 dominant SARS-CoV-2 clades

SARS-CoV-2 프로테옴의 글로벌 변이와 5개의 지배적인 SARS-CoV-2 clades의 사전 잠금 출현 및 보급에 미치는 영향

Article

Published on 2021-09-012022-09-11
Journal: Infection, genetics and evolution : journal of mol [Category] SARS, 변종,

[키워드] addition Analysis Antigen can be used clade clades Comparative analysis curated D614G Diagnosis dissemination dominant early stage facilitate Frequency gene sequence globe Highly recurring mutations independent independent of L37F lack Moderately recurring mutations Mutation Mutational susceptibility mutations N protein nsp10 Nsp12 NSP2 NSP6 occur Occurrence ORF3a ORF8 P323L pandemic performed persistence Phyloproteomics Propagation proteome proteome analysis Q57H SARS-CoV-2 SARS-CoV-2 proteome SARS-CoV-2 viromics. sequence T85I the SARS-CoV-2 Transmission Variation viral evolution whole genome sequence
[DOI] 10.1016/j.meegid.2021.104973 PMC 바로가기 [Article Type] Article

Evolution of antibody responses up to 13 months after SARS-CoV-2 infection and risk of reinfection

SARS-CoV-2 감염 후 13개월까지 항체 반응의 진화 및 재감염 위험

Article

Published on 2021-09-012022-09-11
Journal: EBioMedicine [Category] MERS, SARS, 변종, 진단, 치료법,

[키워드] 95% CI analyzed Anti-RBD antibodies Anti-RBD antibody Anti-RBD IgG antibody Antibody Response Antibody titers assessment B.1.1.7 B.1.351 clinical study Cohort convalescent convalescent individuals COVID-19 COVID-19 negative cross-neutralizing D614G enrolled half-live half-lives HCW healthcare worker Healthcare workers IgG IgG level Immunity incidence individual kinetic Kinetics less log median Neutralization assay neutralization assays neutralized Neutralizing antibodies nucleocapsid protein performed persistence pre-vaccination RBD reached Receptor binding domain reduce reduction in Reinfection risk SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 variants sensitivity serum sample significantly Spike protein subset tested the spike protein university vaccination Vaccine variant variants
[DOI] 10.1016/j.ebiom.2021.103561 PMC 바로가기 [Article Type] Article

New study on prevalence of anosmia in COVID-19 implicates the D614G virus mutation as a major contributing factor to chemosensory dysfunction

COVID-19에서 후각 상실증의 유병률에 대한 새로운 연구는 D614G 바이러스 돌연변이가 화학 감각 기능 장애의 주요 기여 요인임을 암시합니다

Article

Published on 2021-09-012022-09-11
Journal: European archives of oto-rhino-laryngology : offic [Category] SARS, 변종,

[키워드] Anosmia chemosensory COVID-19 D614G dysfunction Mutation New Prevalence virus
[DOI] 10.1007/s00405-021-06759-9 PMC 바로가기 [Article Type] Article

Genome-wide analysis of SARS-CoV-2 strains circulating in Vietnam: Understanding the nature of the epidemic and role of the D614G mutation

베트남에서 유행하는 SARS-CoV-2 균주의 게놈 전체 분석: 전염병의 성격과 D614G 돌연변이의 역할 이해

Article

Published on 2021-09-012022-09-11
Journal: Journal of medical virology [Category] SARS, 변종, 치료기술,

[키워드] 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis Chain Reaction circulating Community Contact tracing coronavirus coronavirus disease Coronavirus disease 2019 country COVID-19 cycle threshold D614G D614G mutation diagnostic test diagnostic tests epidemiological data genome-wide analysis genomic region integration Mutation Next-generation sequencing occur Outbreaks performed polymerase chain polymerase chain reaction Prevalence Prevention and control quarantine SARS-CoV-2 SARS-CoV-2 strain SARS-CoV-2 transmission Sequencing severe acute respiratory syndrome Coronavirus strain Strains the epidemic understanding Vietnam virulence whole-genome sequencing
[DOI] 10.1002/jmv.27103 PMC 바로가기 [Article Type] Article

Energetic and structural basis for the differences in infectivity between the wild-type and mutant spike proteins of SARS-CoV-2 in the Mexican population

멕시코 인구에서 SARS-CoV-2의 야생형 스파이크 단백질과 돌연변이 스파이크 단백질 간의 감염성 차이에 대한 에너지 및 구조적 기초

Article

Published on 2021-09-012022-09-11
Journal: Journal of molecular graphics & modelling [Category] SARS, 변종,

[키워드] ACE2 affinity Analysis approach binding binding affinity binding free energy causative agent conformational conformational flexibility contribute COVID-19 D614G death decrease explained free energy global public health increase in Lineage MD simulation MD simulations molecular molecular dynamics Molecular dynamics simulation Molecular mechanics mutant mutant spike protein pandemic pandemic of COVID-19 performed Protein protein-protein interface S-protein SARS-CoV-2 spike Spike protein Structural analysis surface area the binding affinity the spike protein third position variant virus wild-type X-ray crystallography
[DOI] 10.1016/j.jmgm.2021.107970 PMC 바로가기 [Article Type] Article

Epidemiological analysis in support of hypothesis that D614G virus mutation is a major contributing factor to chemosensory dysfunction in COVID-19 patients

D614G 바이러스 돌연변이가 COVID-19 환자의 화학 감각 기능 장애에 주요 기여 요인이라는 가설을 뒷받침하는 역학 분석

Article

Published on 2021-09-012022-09-11
Journal: European archives of oto-rhino-laryngology : offic [Category] MERS, SARS, 변종, 진단,

[키워드] Analysis chemosensory COVID-19 patient D614G dysfunction Hypothesis Mutation Support virus
[DOI] 10.1007/s00405-021-06941-z PMC 바로가기 [Article Type] Article