Genomic Elucidation of a COVID-19 Resurgence and Local Transmission of SARS-CoV-2 in Guangzhou, China중국 광저우에서 COVID-19 재발 및 SARS-CoV-2의 국소 전파에 대한 게놈 해명Article Published on 2021-07-192022-09-11 Journal: Journal of Clinical Microbiology [Category] SARS, 변종, 유전자 메커니즘, [키워드] Analysis China conducted confirmed case confirmed cases Contact contact with Control coronavirus disease Coronavirus disease 2019 COVID-19 effective Epidemiology event Evidence facilitate First wave genomic genomic data Genomic surveillance Guangzhou Guangzhou, China Households indirect contact Intervention less Local measure outbreak pandemic Phylogeny provide public health public health measure public health measures quarantine reported resurgence SARS-CoV-2 SARS-CoV-2 testing self-quarantine shifting Spread subsequent Surveillance Transmission variant Viral transmission viral variant Viral variants virus while [DOI] 10.1128/JCM.00079-21 PMC 바로가기 [Article Type] Article
Early detection of P.1 variant of SARS-CoV-2 in a cluster of cases in Salvador, Brazil브라질 살바도르의 집단 사례에서 SARS-CoV-2의 P.1 변종 조기 발견Case Reports Published on 2021-07-012022-09-11 Journal: International Journal of Infectious Diseases [Category] SARS, 변종, 치료기술, [키워드] Brazil Cluster COVID-19 Early detection genomic Genomic surveillance highlight indicate Lineage new SARS-CoV-2 P.1 P.1 variant SARS-CoV-2 SARS-CoV-2 P.1 lineage SARS-CoV-2 variant SARS-CoV-2 variants SARS-CoV-2 variants of concern severe COVID-19 Surveillance the SARS-CoV-2 Transmission Travel variants of concern [DOI] 10.1016/j.ijid.2021.05.010 PMC 바로가기 [Article Type] Case Reports
High-precision and cost-efficient sequencing for real-time COVID-19 surveillance실시간 CovID-19 감시를위한 고정밀 및 비용 효율적인 시퀀싱Article Published on 2021-07-012022-09-01 Journal: Scientific Reports [Category] SARS, 변종, 유전자 메커니즘, 진단, [키워드] Amino acid amplified clade coronavirus COVID-19 COVID-19 patients COVID-19 test deaths disease disease outbreaks full-length genome coverage genomic genomic RNA Genomic surveillance High-throughput sequencing individual Los Angele Los Angeles Molecular medicine Mutation nine Nsp12 ORF8 Outbreaks platform positive Precision produced public health reduced Sanger sequencing SARS-CoV-2 sequence sequenced Sequencing sequencing data significantly Surveillance swab specimen the SARS-CoV-2 Threats Transmission USA Viral viral infection Viral RNA whole genome whole genome sequence Whole genome sequencing [DOI] 10.1038/s41598-021-93145-4 PMC 바로가기 [Article Type] Article
COVseq is a cost-effective workflow for mass-scale SARS-CoV-2 genomic surveillanceCOVseq는 대규모 SARS-CoV-2 게놈 감시를 위한 비용 효율적인 워크플로입니다.Article Published on 2021-06-232022-09-10 Journal: Nature Communications [Category] MERS, SARS, 변종, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis application can be used Concordance coronavirus Cost analysis Critical detect DNA sequencing downstream generate genomic Genomic analysis Genomic surveillance Illumina Illumina platforms Influenza influenza viruses less MONITOR pathogen Pathogens phylogenetic analyses platform positive positive sample respiratory SARS-CoV-2 SARS-CoV-2 genomic surveillance sequence Sequencing severe acute respiratory syndrome Coronavirus single-nucleotide Spread standard library Surveillance vaccination variant variants variants of concern Viral viral variant Viral variants viruses VoC while [DOI] 10.1038/s41467-021-24078-9 PMC 바로가기 [Article Type] Article
Comparative Genomics Reveals Early Emergence and Biased Spatiotemporal Distribution of SARS-CoV-2비교 유전체학은 SARS-CoV-2의 조기 출현 및 편향된 시공간 분포를 나타냅니다Discoveries Published on 2021-06-192022-09-10 Journal: Molecular Biology and Evolution [Category] SARS, 변종, 유전자 메커니즘, [키워드] 3′-UTR absence Analysis approach approaches changes in China circulation classification Clinical characteristics Clusters Comparative Comparative genomics complement conserved contributing to convergent evolution COVID 19 Defense distribution driven by early emergence emergence epidemiological epidemiological studies Epidemiological study Evidence evidence of Evolution exhibiting facilitate fixation functional genetic profile Genetic variant genetic variants Genome sequences genomes genomic Genomic surveillance Genomic variability Genomics Geographic distribution highlight human pathogen independent Infectious disease Infectious diseases isolates Isolation Metadata molecular data open outbreak outlined pandemic pathogen Pathogens phenotypic feature Phylogenetic polymorphic site positive predicted question sampling SARS-CoV-2 SARS-CoV-2 isolate SARS-CoV-2 isolates secondary structure Seven spatiotemporal Spread Strains substitutions Surveillance unlikely UTR UTRs Validity Variability variant Viral viral genome viral strains virus widespread [DOI] 10.1093/molbev/msab049 PMC 바로가기 [Article Type] Discoveries
Spread of a SARS-CoV-2 variant through Europe in the summer of 2020 Research Published on 2021-06-072022-10-05 Journal: Nature [Category] SARS, 변종, 유전자 메커니즘, [키워드] absence Affect Containment strategy Critical dominant effective effort epidemiological Europe European country Evidence explain Genomic surveillance incidence infection with SARS-CoV-2 introduced lack Local Phylogenetic analysis reduced rising SARS-CoV-2 variant Spain Spread Transmissibility Transmission transmission of SARS-CoV-2 Travel variant viral genome sequence virus spread [DOI] 10.1038/s41586-021-03677-y [Article Type] Research
Preliminary report on severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) Spike mutation T478KShort Communication Published on 2021-05-152022-10-04 Journal: Journal of medical virology [Category] SARS, 변종, 치료기술, [키워드] acute respiratory syndrome affecting Amino acid analyzed B.1.1.7 B.1.351 binding domain coronavirus coronavirus disease COVID‐19 detect Drug efficacy electrostatic European experiment Frequency Genetic genomic sequence Genomic surveillance GISAID immune independent Interaction Lineage Mutation North America Protein receptor ACE2 Repository S:T478K SARS‐CoV‐2 SARS‐CoV‐2 spike SARS‐CoV‐2 sequence spike Spike:T478K T478K the Spike The United States Vaccine variant [DOI] 10.1002/jmv.27062 PMC 바로가기 [Article Type] Short Communication
Early introductions and transmission of SARS-CoV-2 variant B.1.1.7 in the United StatesArticle Published on 2021-05-132023-06-19 Journal: Cell [Category] MERS, SARS, [키워드] B.1.1.7 community transmission Epidemiology flight volumes Genomic surveillance introductions Lineage phylogenetics SARS-CoV-2 variant [DOI] 10.1016/j.cell.2021.03.061 PMC 바로가기
Emerging variants of concern in SARS-CoV-2 membrane protein: a highly conserved target with potential pathological and therapeutic implicationsSARS-CoV-2 막 단백질에서 우려되는 새로운 변종: 잠재적인 병리학적 및 치료적 의미를 지닌 고도로 보존된 표적Research Article Published on 2021-05-092022-09-10 Journal: Emerging Microbes & Infections [Category] SARS, 변종, [키워드] accounted age B.1 lineage B.1.1.7 B.1.429 clade conjunction conserved COVID-19 defined dominant lineage e genes effort ENCODE Europe Frequency functions genomic Genomic surveillance Glucose host cell implicated implication Implications incidence increase in initial isolate isolates Lineage lineages M gene M:I82T mutation membrane membrane protein Mutation mutations pangolin pathogenic Patient patient age Protein reported SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes structural protein sulphate Surveillance the SARS-CoV-2 therapeutic transmembrane Transport USA variant of concern variants of concern Viral Viral protein viral replication while [DOI] 10.1080/22221751.2021.1922097 PMC 바로가기 [Article Type] Research Article
Genomic Evidence of SARS-CoV-2 Reinfection Involving E484K Spike Mutation, BrazilE484K 스파이크 돌연변이와 관련된 SARS-CoV-2 재감염의 게놈 증거, 브라질Case Reports Published on 2021-05-012022-09-10 Journal: Emerging Infectious Diseases [Category] MERS, SARS, 변종, 유전자 메커니즘, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Brazil coronavirus coronavirus disease COVID-19 E484K E484K mutation E484K spike mutation escape evidence of Genomic surveillance immune responses Involving Lineage Neutralizing antibodies persists protective immune response recovered patient recovered patients Reinfection reported respiratory respiratory infections SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 spike Uncertainty variant virus viruses zoonoses [DOI] 10.3201/eid2705.210191 PMC 바로가기 [Article Type] Case Reports