Lungs as target of COVID-19 infection: Protective common molecular mechanisms of vitamin D and melatonin as a new potential synergistic treatmentReview article Published on 2020-08-012022-10-05 Journal: Life sciences [Category] SARS, 치료법, [키워드] accompanied acute respiratory syndrome affecting approach association COVID-19 COVID-19 infection COVID-19 pandemic death down-regulated Efficacy exacerbated high mortality rate immune Inflammation inflammatory reaction Inflammatory response Interaction lung mechanism melatonin modulate molecular mechanism Older organs Oxidation oxidative oxidative stress pathology pharmacological agent RAS renin-angiotensin system risk severity synergistic therapeutic Treatment Vitamin D [DOI] 10.1016/j.lfs.2020.117808 [Article Type] Review article
Effect of Coronavirus Disease 2019 in Pulmonary Circulation. The Particular Scenario of Precapillary Pulmonary HypertensionReview Published on 2020-07-312022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] affecting angiotensin-converting enzyme 2 Anticoagulant benefit cardiovascular disease Characteristics clinical entities clinical picture Comorbidities condition COVID-19 COVID-19 case described dysfunction Effect Endothelial dysfunction Endothelium explain feature health emergency high mortality rate incidence Inflammation International involved management mechanism PAH Particular pathophysiological pathophysiology Patient Precapillary protective effect pulmonary pulmonary arterial hypertension pulmonary circulation pulmonary hypertension reported respiratory infections scenario severity severity of COVID-19 similarity specific treatment thromboembolic thrombosis vasoconstriction ventilation/perfusion [DOI] 10.3390/diagnostics10080548 PMC 바로가기 [Article Type] Review
Mesenchymal stem cells: current clinical progress in ARDS and COVID-19Review Published on 2020-07-222022-10-29 Journal: Stem Cell Research & Therapy [Category] COVID-19, SARS, [키워드] acute respiratory distress syndrome animal model ARDS Cell Cell therapy clinical implication Clinical management clinical trials coronavirus disease COVID-19 current develop distress Factors fluid input high mortality rate Lung diseases Mesenchymal stem cells Mesenchymal stromal cell MSC MSCs pandemic pharmacological treatment protective effect Quality of life reported Respiratory Support shown suggested syndrome therapy Treatment [DOI] 10.1186/s13287-020-01804-6 PMC 바로가기 [Article Type] Review
COVID-19: Underlying Adipokine Storm and Angiotensin 1-7 UmbrellaImmunology Published on 2020-07-212022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] ACE2 acute respiratory syndrome adipocyte Adipokine angiotensin Angiotensin 1-7 association coronavirus CoV COVID-19 deregulation dysfunction enzyme explain feature greater Health high mortality rate host cells immune Infection infections Inflammation low expression metabolic syndrome obese patient obesity outbreak pandemic patients Protein receptor Research Respiratory failure SARS-CoV SARS-CoV-1 SARS-CoV-2 Scientific community severity of COVID-19 Severity of infection storm syndrome the SARS-CoV-2 therapeutic type 2 diabete UMBRELLA unique [DOI] 10.3389/fimmu.2020.01714 PMC 바로가기 [Article Type] Immunology
Serum IgM against SARS-CoV-2 correlates with in-hospital mortality in severe/critical patients with COVID-19 in Wuhan, ChinaPriority Research Paper Published on 2020-07-152022-10-28 Journal: Aging (Albany NY) [Category] COVID-19, SARS, [키워드] adverse event antibody Antibody Response ARDS Asia change Clinical outcome cohort study conducted coronavirus disease correlated COVID-19 COVID-19 progression declined described global pandemic high mortality rate higher risk IgG IgM illness onset Immunoglobulin in-hospital mortality incidence intensive care IQR median outcome Patient patients patients with COVID-19 performed respiratory retrospective SARS-CoV-2 Sepsis serum severe acute respiratory syndrome coronavirus 2 Shock significantly single-center survivor were measured Wuhan Wuhan, China [DOI] 10.18632/aging.103417 PMC 바로가기 [Article Type] Priority Research Paper
Obesity and COVID-19: Oro-Naso-Sensory PerceptionReview Published on 2020-07-082022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] acute respiratory syndrome aggravate alteration Anosmia change clinical manifestation coronavirus disease Coronavirus-2 COVID-19 expression Fever flu-like symptoms health condition high mortality rate in some include Infection obese obese COVID-19 patients obesity ONS pandemic pathology Patient Perception receptors reduced responsible risk factor SARS-CoV-2 SARS-COV-2 infection shown Smell sore throat subject subjects Symptoms Taste the SARS-CoV-2 Thoracic viral infections [DOI] 10.3390/jcm9072158 PMC 바로가기 [Article Type] Review
High Inflammatory Burden: A Potential Cause of Myocardial Injury in Critically Ill Patients With COVID-19Cardiovascular Medicine Published on 2020-07-072022-10-31 Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19, [키워드] addition Admission age analyzed assessment cause chronic Clinical characteristics cohort study Comorbidity confidence interval correlation COVID-19 COVID-19 patient Cox regression critical patients Critically ill patient death demographic develop diagnosed enrolled exceeded failure had more hazard ratio high mortality high mortality rate High-sensitivity C-reactive protein IL-10 IL-6 IL-8 Ill In-ICU mortality incidence independent risk factor Inflammation Inflammatory Injury Laboratory tests limits Logistic regression median Mortality myocardial injury novel coronavirus disease Occurrence Odds ratio Older outcome Patient patients patients with COVID-19 Physiology plasma Plasma level positively correlated Potential receptor retrospective risk factor score significantly higher single-center smoking statistically suggested the mean TNF-α tumor necrosis factor-α two group with COVID-19 [DOI] 10.3389/fcvm.2020.00128 PMC 바로가기 [Article Type] Cardiovascular Medicine
Plasmapheresis treatment in COVID-19–related autoimmune meningoencephalitis: Case seriesShort communication Published on 2020-07-012022-10-05 Journal: Brain, behavior, and immunity [Category] SARS, 치료법, [키워드] Autoimmune COVID-19 Encephalitis high mortality rate ICU Infection intensive care unit Plasmapheresis SARS-CoV-2 severely ill patient Treatment [DOI] 10.1016/j.bbi.2020.05.022 [Article Type] Short communication
A close look at the biology of SARS-CoV-2, and the potential influence of weather conditions and seasons on COVID-19 case spreadOpinion Published on 2020-06-262022-10-29 Journal: Infectious Diseases of Poverty [Category] COVID-19, SARS, [키워드] acute respiratory syndrome aetiology biochemical biology of SARS-CoV-2 Case spread characterized China condition conditions coronavirus coronavirus disease Coronaviruses country COVID-19 COVID-19 case COVID-19 infection COVID-19 pandemic Effectiveness emergency preparedness epidemiological Evidence Factor flu global pandemic globe high mortality rate highlight human immunity human population Immunity include increasingly infected with COVID-19 infection control Influenza virus likelihood métapneumovirus Middle East Other outbreak outcomes respiratory syncytial virus respiratory syndrome coronavirus SARS-CoV-2 season Spread Support susceptibility temperature viral pathogen virus virus spread [DOI] 10.1186/s40249-020-00688-1 PMC 바로가기 [Article Type] Opinion
Gut-lung axis and dysbiosis in COVID-19Article Published on 2020-06-212022-10-29 Journal: Turkish Journal of Biology [Category] COVID-19, [키워드] affected age association bidirectional relationship cause caused conditions contribute Course COVID-19 COVID-19 patient COVID-19 severity decrease demonstrated described disease Dysbiosis Evidence Gastrointestinal symptom Gut gut barrier integrity gut microbiota gut permeability gut-lung axis high mortality rate high risk homeostasis Host immune system indicate infected patient Infection Infectious disease Infectious virus Interaction intestinal lumen lung Lung infection maintain Medical conditions multiple organ failure Older Particle Patient required SARS- CoV-2 SARS-CoV-2 SARS-COV-2 infection Sepsis severity translocation Transmission viral infection viral particle Viral RNA [DOI] 10.3906/biy-2005-102 PMC 바로가기 [Article Type] Article