Ivermectin
[대역어] 이버멕틴
[용어속성] Drug
[용어속성] Drug
Nebulized ivermectin for COVID-19 and other respiratory diseases, a proof of concept, dose-ranging study in rats
Article
[키워드] adipose
adjusted
Administered
alveolar
Anomaly
antiparasitic drug
assigned
Biochemistry
C max
changes in
Concentration
conducted
control group
COVID-19
detectable
dose
drug delivery
Drug development
Efficacy
enzyme
experiment
female
females
full blood count
groups
High-dose
histological
in vitro
Ivermectin
ivermectin dose
low-dose
lower dose
lung
lung tissue
male
nebulized
Particle
pharmacokinetic
plasma
plasma concentration
post intervention
Preclinical research
Randomly
RAT
reached
recent
reduction
required
respiratory diseases
RNA viruses
Safe
SARS-CoV-2 replication
Seven
subject
therapy
toxicology
was determined
[DOI] 10.1038/s41598-020-74084-y PMC 바로가기 [Article Type] Article
[DOI] 10.1038/s41598-020-74084-y PMC 바로가기 [Article Type] Article
Three novel prevention, diagnostic, and treatment options for COVID-19 urgently necessitating controlled randomized trials
Research article
[키워드] activate
acute respiratory distress syndrome
Alpha
alveolar
Anti-inflammatory therapy
Anti-viral
anti-viral effect
anticoagulant therapy
anticoagulation
approach
ARDS
ARDSacute respiratory distress syndrome
Bacterial
Beta
Blood
C-reactive protein
Care
Cell
chemokines
clinical outcomes
clinically
Coagulopathy
Comorbidities
Computerized tomography
concerning
Coronaviruses
COVID-19
COVID-19 infection
CoVscoronaviruses
criteria
CRPC-reactive protein
CTcomputerized tomography
CXCL10chemokines
CXCL9
cytokine
D-dimer
diagnose
Diagnosis
diagnostic
DICdisseminated intravascular coagulation
Digital
Disseminated intravascular coagulation
distress
effective
elevated
emboli
extreme
General population
GGOground glass opacities
gluthathione
ground glass opacities
GSHgluthathione
Health
Health authority
healthy
help
high mortality rate
highest
hypothetical
ICUIntensive Care Unit
identify
IL-10interleukin 10
IL-12interleukin 12
IL-18interleukin 18
IL-1βinterleukin 1 beta
IL-33interleukin 33
IL-6interleukin 6
IL-7Interleukin 7
IL-8interleukin 8
immune
immune function
immunomodulatory
implementation
increase in
individual
individuals
Inflammation
intensive care unit
interleukin 1 beta
Interleukin 10
interleukin 12
interleukin 18
interleukin 33
interleukin 6
Interleukin 7
interleukin 8
Intervention
Isolation
Ivermectin
lactic dehydrogenase
LDHlactic dehydrogenase
LDLyme disease
literature review
Lyme disease
macrophage activation syndrome
MASmacrophage activation syndrome
MERS coronavirus
MERS-CovMERS coronavirus
morbidity and mortality
Multiorgan dysfunction
N-acetyl-cysteine
NACN-acetyl-cysteine
NCPnovel coronavirus pneumonia
New
NF-κB
novel coronavirus pneumonia
NSnutritional support
nutraceutical
nutritional support
organ
outcomes
oxygen
Oxygenation
pandemic
Pathways
Patient
performed
physical distancing
Pneumonia
precursor
Prevent
protocol
questionnaire
Randomized controlled trial
randomized trial
randomized, controlled trials
required
resource
respiratory therapy
resulting
risk
SARS-CoV-2severe acute respiratory syndrome coronavirus 2
scored
screening questionnaire
second
Sepsis
serum
severe acute respiratory syndrome coronavirus 2
severe complication
silent
statistical
statistically
Stress
sulforaphane
Support
Symptom
symptomatic infection
TGFβtransforming growth factor beta
the disease
therapy
thrombotic event
TNF-αtumor necrosis factor alpha
transforming growth factor beta
Transmission
Treatment
Treatment strategies
tumor necrosis factor alpha
ventilator
vital sign
Vitamin C
WHOWorld Health Organization
with COVID-19
World Health Organization
[DOI] 10.1016/j.mehy.2020.109851 [Article Type] Research article
[DOI] 10.1016/j.mehy.2020.109851 [Article Type] Research article
Recognition of Potential COVID-19 Drug Treatments through the Study of Existing Protein–Drug and Protein–Protein Structures: An Analysis of Kinetically Active Residues
Article
[키워드] α-difluoromethylornithine (DMFO)
active sites
Analysis
applied
approach
approved drug
boceprevir
Chloroquine
Community
COVID-19
drug
drug design
facilitate
hydrophobic
IMPROVE
in silico
include
interactions
Ivermectin
molecular
normal-modes
Potential
Potential treatment
Protein
protein–drug interactions
Proteins
Recognition
Remdesivir
residue
small molecule
sofosbuvir
spike glycoprotein
virus
[DOI] 10.3390/biom10091346 PMC 바로가기 [Article Type] Article
[DOI] 10.3390/biom10091346 PMC 바로가기 [Article Type] Article
Pathophysiology and Potential Therapeutic Candidates for COVID-19: A Poorly Understood Arena
Pharmacology
[키워드] absence
acute respiratory syndrome
Anti-inflammatory
antibody
antimalarial
antiparasitic drug
Antiviral
arena
available data
benefit
candidate
Candidates
caused
cellular therapy
China
chloroquine/hydroxychloroquine
city
claimed
clinical manifestation
clinical trial
clinically
controls
convalescent plasma
coronavirus
Coronavirus disease 2019
COVID-19
criteria
cytokine
drug
Drug repurposing
effective
Epidemics
evaluated
Evidence
explain
Favipiravir
global pandemic
Guidance
identify
Immunotherapy
imperative
IMPROVE
in vitro activity
include
Inconclusive
initiation of treatment
interferon
investigational agent
Ivermectin
lack
MERS
Middle East
monoclonal
Natural killer cells
observational study
outcome
outcomes
pathology
pathophysiology
Patient
patient selection
Pneumonia
Population
Potential
Potential treatment
Prevent
progression
receptor
Remdesivir
Repurposed drug
responsible
SARS-CoV-2
severe acute respiratory syndrome coronavirus 2
small sample size
stem cell
syndrome
target
the disease
the patient
the timing
Therapeutic strategies
therapeutic strategy
therapy
Treatment
treatment guidelines
umifenovir
understanding
Understood
Vaccine
virus
Wuhan
[DOI] 10.3389/fphar.2020.585888 PMC 바로가기 [Article Type] Pharmacology
[DOI] 10.3389/fphar.2020.585888 PMC 바로가기 [Article Type] Pharmacology
Ivermectin as a Broad-Spectrum Host-Directed Antiviral: The Real Deal?
Review
[키워드] Adenovirus
Antiviral
antiviral action
approved
cell culture experiment
Chikungunya virus
complex
conformational change
COVID-19
dengue virus
drug
eight
flavivirus
food
heterodimeric
HIV-1
Host
host proteins
Human
human clinical trial
induce
infections
inhibiting
Ivermectin
nuclear
phase
Prevent
Protein
Pseudoraby
robust
SARS-CoV-2
shown
Trial
Venezuelan equine encephalitis
virus
viruses
West Nile Virus
Zika virus
[DOI] 10.3390/cells9092100 PMC 바로가기 [Article Type] Review
[DOI] 10.3390/cells9092100 PMC 바로가기 [Article Type] Review
A new advanced in silico drug discovery method for novel coronavirus (SARS-CoV-2) with tensor decomposition-based unsupervised feature extraction
텐서 분해 기반 비지도 특징 추출을 통한 신종 코로나바이러스(SARS-CoV-2)에 대한 새로운 첨단 in silico 약물 발견 방법
Research Article
[키워드] acute respiratory syndrome
acute respiratory syndrome coronavirus
acute respiratory syndrome coronavirus 2
affected
alvocidib
antiviral drug
applied
atorvastatin
candidate
canertinib
cell line
chloride
clinical trial
clinical trials
Community
Compound
coronavirus
costly
COVID-19
Critical
develop
dibromochloromethane
doxycycline
drug
drug candidate
Drug discovery
effective
effective drug
effective drugs
experimental validation
expression
fluticasone
gadolinium
geldanamycin
gene expression profile
Gene expression profiles
gentamicin
identify
in silico
Ivermectin
lung cancer
meloxicam
mitoxantrone
motexafin gadolinium
Novel coronavirus
Numerous
pandemic
patients with COVID-19
quercetin
radicicol
respiratory
SARS-CoV-2
Screen
screened
selected
severe acute respiratory syndrome Coronavirus
significantly
sorafenib
Tensor
time-consuming
treating COVID-19
trovafloxacin
[DOI] 10.1371/journal.pone.0238907 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.pone.0238907 PMC 바로가기 [Article Type] Research Article
Ivermectin: A Closer Look at a Potential Remedy
Internal Medicine
[키워드] acute respiratory syndrome
anti-influenza drug
Antiviral
antiviral property
antiviral therapy
benefit
caused
clinical trial
Concentration
coronavirus
coronavirus 2019 (COVID-19)
coronavirus disease
COVID-19
described
effective
Favipiravir
Hydroxychloroquine
in vivo
Inhaled
inhaled antivirals
Ivermectin
lung
management
NIH
Numerous
pandemic
patients with COVID-19
Pneumonia
Potential
remedisivir
remedy
SARS-CoV-2
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
shown
survival
the SARS-CoV-2
Treatment
Vaccine
WHO
World Health Organization
[DOI] 10.7759/cureus.10378 PMC 바로가기 [Article Type] Internal Medicine
[DOI] 10.7759/cureus.10378 PMC 바로가기 [Article Type] Internal Medicine
Strongyloides infection manifested during immunosuppressive therapy for SARS-CoV-2 pneumonia
SARS-CoV-2 폐렴에 대한 면역억제 치료 중 나타난 Strongyloides 감염
Case Reports
[키워드] abdominal pain
bilateral pneumonia
Complication
Corticosteroid
Corticosteroids
Course
cytokine
cytokine inhibitor
cytokine inhibitors
Dexamethasone
eosinophil
Eosinophil count
Evidence
full recovery
High dose
High-dose
Hyperinflammatory
Immunosuppression
immunosuppressive
Immunosuppressive agents
immunosuppressive therapy
Infection
infections
interstitial
intravenous
intravenous dose
involved
Italian
itching
Ivermectin
Latent infections
manifested
Pathogenesis
Patient
Pneumonia
public health
Reactivation
risk
SARS-CoV-2
SARS-COV-2 infection
SARS-CoV-2 pandemic
SARS-CoV-2 pneumonia
severe COVID-19
severe disease
steroid
Steroids
Stool examination
Strongyloides stercoralis
strongyloidiasis
suggested
therapy
Tocilizumab
treated
Treatment
[DOI] 10.1007/s15010-020-01522-4 PMC 바로가기 [Article Type] Case Reports
[DOI] 10.1007/s15010-020-01522-4 PMC 바로가기 [Article Type] Case Reports
Clinical Presentation, Management and In-Hospital Outcome of Healthcare Personnel With COVID-19 Disease
Cardiology
[키워드] age
Analysis
Anosmia
Asymptomatic
Characteristics
clinical
clinical presentation
close contact
Cohort
conducted
coronavirus disease
cough
COVID-19
COVID-19 disease
COVID-19 infection
COVID-19 pandemic
cross-sectional
died
disease
doxycycline
evaluate
fatigue
female
Fever
foundation
hcp
headache
healthcare worker
heart
Home isolation
hospital
Hospitalized
in-hospital outcome
Infection
infection rate
Isolation
Ivermectin
mandatory
media
Mild
mild COVID-19 symptom
Mild symptom
moderate disease
MOST
Nasopharyngeal samples
Nurse
objective
onset of symptom
outcome
pandemic
Patient
physician
positive
presentation
reported
respiratory symptom
Result
severe disease
study population
subject
Symptom
tested
treated
Treatment
was performed
with COVID-19
[DOI] 10.7759/cureus.10004 PMC 바로가기 [Article Type] Cardiology
[DOI] 10.7759/cureus.10004 PMC 바로가기 [Article Type] Cardiology