In vivo evaluation of the virucidal efficacy of chlorhexidine and povidone-iodine mouthwashes against salivary SARS-CoV-2. A randomized-controlled clinical trialRandomized Controlled Trial Published on 2021-09-012022-10-05 Journal: The journal of evidence-based dental practice [Category] SARS, 임상, [키워드] 1% Povidone-iodine gargle age Analysis antimicrobial carried chlorhexidine Chlorhexidine 0.2% mouthrinse clinical trial collected control group COVID-19 COVID-19 positive patient cross-contamination cycle threshold dentistry effective Efficacy enrolled evaluate experiment female GraphPad Prism groups in vivo laboratory-confirmed less male material mouthwashe nasopharyngeal swabs no significant difference paired t-test participant Patient performed povidone-iodine prevention Probability randomized-controlled reduce reduction risk rRT-PCR saliva sample salivary Salivary SARS-CoV-2. SARS-CoV-2 SARS-CoV-2 viral load significant difference spread of COVID-19 statistically significant virucidal were used windows [DOI] 10.1016/j.jebdp.2021.101584 PMC 바로가기 [Article Type] Randomized Controlled Trial
Performance of saliva as a specimen to detect SARS-CoV-2SARS-CoV-2 검출을 위한 검체로서의 타액의 성능Article Published on 2021-09-012022-09-11 Journal: Journal of Clinical Virology [Category] SARS, 치료기술, [키워드] affected alternative average COVID-19 Ct-value Ct-values detect Detection sensitivity Epidemic False negative False negative rate false negatives functions Health increase in massive Nasopharyngeal swab nasopharyngeal swabs NPs ORF1 ORF1ab Patient performance positive RNA RNA extraction RT-PCR Saliva saliva samples SARS-CoV-2 sensitivities sensitivity specimen Standard deviation the patient Variability viral gene viral genes [DOI] 10.1016/j.jcv.2021.104913 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Infection Rate in Patients With Cancer and Health Care Workers in a Chemoradiotherapy Unit During the Pandemic: A Prospective Cohort in Mexico팬데믹 기간 동안 화학방사선치료실에서 암 환자 및 의료 종사자의 SARS-CoV-2 감염률: 멕시코의 예상 코호트Article Published on 2021-09-012022-09-11 Journal: JCO Global Oncology [Category] SARS, 치료기술, [키워드] anti-SARS-CoV-2 antibody anti-SARS-CoV-2 immunoglobulin antibody Asymptomatic asymptomatic infections baseline Biweekly Cancer cancer treatment center Chain Reaction chemoradiotherapy clinical questionnaire contagious COVID-19 COVID-19 pandemic COVID-19-related symptom COVID-19-related symptoms cumulative death detect determine diagnostic events Follow-up HCW Health care Health care worker health care workers Hospitalization IgG Immunoglobulin Immunoglobulin G incidence infection rate Informed consent Interaction likelihood ratio median Mexico City Nasopharyngeal swab nasopharyngeal swabs outcomes Participants Patient patient safety Patients with cancer performed polymerase chain polymerase chain reaction positive Positive predictive value positive RT-PCR Predictive value Prevent Prospective provided Quantitative Rate receive reverse transcriptase Reverse transcriptase polymerase chain reaction RT-qPCR SARS-CoV-2 SARS-CoV-2 IgG SARS-COV-2 infection sensitivity Seroconversion seroconversion rate solid tumor solid tumors study period transcriptase Transmission Treatment tumors unit was performed were measured were recorded worker [DOI] 10.1200/GO.21.00207 PMC 바로가기 [Article Type] Article
Validation of GeneXpert testing for SARS-CoV-2 RNA in eight hospital laboratories in Oman오만의 8 개의 병원 실험실에서 SARS-COV-2 RNA에 대한 유전자 테스트 검증Comparative Study Published on 2021-09-012022-09-01 Journal: The Pan African Medical Journal [Category] SARS, 진단, 치료기술, [키워드] aims Cepheid comparison coronavirus country COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients cross-sectional cross-sectional study Ct values diagnostic diagnostic testing E gene eight evaluate highlight hospital Kingfisher Laboratory Liferiver molecular N gene Nasopharyngeal swab nasopharyngeal swabs National Oman ORF ORF gene Patient performed point of care presenting Public public health emergency Roche routine diagnostic testing RT-PCR RT-PCR kit RT-PCR kits SARS-CoV-2 SARS-CoV-2 RNA Sensitivity and specificity specimens Swab Testing TIB MOL BIOL validation Viral Viral load viral loads was tested was used [DOI] 10.11604/pamj.2021.40.2.27224 PMC 바로가기 [Article Type] Comparative Study
SARS-CoV-2 RNAaemia in children: An Iranian referral hospital-based study소아의 SARS-CoV-2 RNAaemia:이란 의뢰 병원 기반 연구Article Published on 2021-09-012022-09-11 Journal: Journal of medical virology [Category] SARS, 바이오마커, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adults association Blood coronavirus coronavirus disease Coronavirus disease 2019 cough COVID-19 creatine creatine phosphokinase disease severity evaluate Fever groups individual Laboratory laboratory findings Laboratory tests Magnesium marker Mortality nasopharyngeal swabs patients patients with SARS-CoV-2 Pediatric patient Pediatric patients pediatrics positive predict reported respiratory RNA RNAaemia SARS-CoV-2 SARS-CoV-2 RNA detection severe acute respiratory syndrome Coronavirus severe COVID-19 severity significant difference significant differences Symptom tachypnea the disease the patient the SARS-CoV-2 Viral Viral RNA vomiting [DOI] 10.1002/jmv.27065 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Infection Modulates ACE2 Function and Subsequent Inflammatory Responses in Swabs and Plasma of COVID-19 PatientsSARS-COV-2 감염은 COVID-19 환자의 면봉 및 혈장에서 ACE2 기능 및 후속 염증 반응을 조절합니다.Article Published on 2021-08-282022-09-10 Journal: Viruses [Category] MERS, SARS, 바이오마커, 유전자 메커니즘, [키워드] ACE2 ACE2 expression ACE2 gene angiotensin angiotensin converting enzyme angiotensin converting enzyme 2 Biomarker change changes in Course COVID-19 Cytokines enzymatic activity enzyme expression function functional Host increase infected patients Infection Inflammation Inflammatory cytokines Inflammatory response Interaction mechanism modulate Nasopharyngeal swab nasopharyngeal swabs plasma plasma sample plasma samples positively correlated receptor Release respiratory response SARS-CoV-2 SARS-CoV-2 infected patients SARS-COV-2 infection SARS-CoV-2 virus SARS-CoV-2-ACE2 severity soluble ACE2 subsequent Swab swabs target cells tested the SARS-CoV-2 virus upper respiratory tract Viral viral entry viral infection Viral load [DOI] 10.3390/v13091715 PMC 바로가기 [Article Type] Article
Performance of Seven SARS-CoV-2 Self-Tests Based on Saliva, Anterior Nasal and Nasopharyngeal Swabs Corrected for Infectiousness in Real-Life Conditions: A Cross-Sectional Test Accuracy StudyArticle Published on 2021-08-282022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] addition Anterior anterior nasal swab Antigen calculated COVID-19 criteria Culture cycle threshold evaluate evaluated Evaluation independent infectiousness nasal swab nasopharyngeal Nasopharyngeal swab nasopharyngeal swabs PCR performance performed Predictive qPCR quantitative PCR Rapid antigen tests reported Saliva SARS-CoV-2 sensitivities sensitivity Seven specificity Swab symptomatic status Test the WHO viability virus virus culture was performed [DOI] 10.3390/diagnostics11091567 PMC 바로가기 [Article Type] Article
Single-cell transcriptome identifies FCGR3B upregulated subtype of alveolar macrophages in patients with critical COVID-19Article Published on 2021-08-252022-10-04 Journal: iScience [Category] 바이오마커, 변종, 유전자 메커니즘, [키워드] Abstract alveolar macrophage analyzed Biomarker Bronchoalveolar lavage fluid CCL3L1 Cell Comorbidity COVID-19 COVID-19 cases COVID-19 severity Critical critical cases disease Evidence FCGR3B healthy controls heterogeneity host cell ICU identify life-threatening marker mechanism Molecular biology multiple tissue specimen Nasopharyngeal swab nasopharyngeal swabs older patient Patient Pneumonia positive potential therapeutic target Prognosis severe COVID-19 severe COVID-19 cohort significantly single-cell subset those with comorbidities Transcriptome transcriptomic data transcriptomics understanding upregulated upregulation Virology [DOI] 10.1016/j.isci.2021.103030 PMC 바로가기 [Article Type] Article
Efficacy of Unsupervised Self-Collected Mid-Turbinate FLOQSwabs for the Diagnosis of Coronavirus Disease 2019 (COVID-19)코로나 바이러스 질병의 진단을위한 감독되지 않은 자체 수집 된 중간-터지니어 플로 크 스웨이 (Covid-19)의 효능Article Published on 2021-08-222022-09-01 Journal: Viruses [Category] MERS, 진단, [키워드] Accuracy acute respiratory syndrome Analysis Care clinic collected coronavirus disease Coronavirus disease 2019 COVID-19 Diagnosis diagnosis of SARS-CoV-2 diagnostic dry swab Efficacy enrolled exposure to Health Health care health care workers Infection Laboratory medium Molecular diagnosis Nasopharyngeal swab nasopharyngeal swabs offer outbreak pandemic reducing respiratory room temperature SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus SARS-CoV-2 virus infection severe acute respiratory syndrome coronavirus-2 specimen Surveillance Swab swabs temperature the SARS-CoV-2 virus to define Transmission transported Travel unsupervised self-collection virus infection without affecting [DOI] 10.3390/v13081663 PMC 바로가기 [Article Type] Article
Development of an alternative saliva test for diagnosis of SARS-CoV-2 using TRIzol: Adapting to countries with lower incomes looking for a large-scale detection programTrizol을 사용한 SARS-COV-2 진단을위한 대체 타액 검사 개발 : 대규모 탐지 프로그램을 찾고있는 소득이 낮은 국가에 적응Research Article Published on 2021-08-182022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 진단, 치료기술, [키워드] 2019-nCoV added Asymptomatic buffer caused CDC comparable coronavirus costly country development Diagnosis diagnosis of SARS-CoV-2 extraction Families handling healthcare healthcare worker Healthcare workers healthy help infected patients Infection less Mortality Nasopharyngeal swab nasopharyngeal swabs Non-invasive not need Novel coronavirus NPs one patient Panel Patient patient with SARS-CoV-2 patients with SARS-CoV-2 performed Personal protective equipment positive quarantine real-time RT-PCR reduce RNA room temperature RT-PCR RT-qPCR Saliva saliva test SARS-CoV-2 SARS-CoV-2 RNA Schools shown storage temperature Trizol Viral viral inactivation virus [DOI] 10.1371/journal.pone.0255807 PMC 바로가기 [Article Type] Research Article