The Predictive Value of Mutation Screening for Anticipating COVID-19 WavesCommunication Published on 2021-11-112022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] can be used Care COVID-19 COVID-19 case deaths Delta drastic Efficacy Efficiency FIVE generate genotyping gold standard growth Health help immune response increase in increases in Infection marker mathematical measure molecular Mutation Pandemics Positive predictive value PPV prediction Predictive Prevalence professional raising reduce cost SARS-CoV-2 strain Screening screening test strain Surveillance Transmissibility value variant variants Wave WGS [DOI] 10.3390/pathogens10111464 PMC 바로가기 [Article Type] Communication
A Prediction Model for High Risk of Positive RT-PCR Test Results in COVID-19 Patients Discharged From Wuhan Leishenshan Hospital, China중국 우한 레이선산 병원에서 퇴원한 코로나19 환자의 RT-PCR 양성 반응 고위험 예측 모델Public Health Published on 2021-11-082022-09-11 Journal: Frontiers in Public Health [Category] MERS, SARS, 치료기술, [키워드] benefit China Chinese Clinical characteristics COVID-19 Desaturation discharge discharged discharged patient enrolled Factor Follow-up high risk higher risk hospital discharge Hospital stay less mathematical Model nucleic acid offered oxygen Particular Patient patients patients with COVID-19 positive Positive test predict prediction re-detectable recovered reduce reported Result risk RT-PCR SARS-CoV-2 RNA Test Traditional Chinese medicine Traditional Chinese medicine treatment Treatment Wuhan Wuhan, China [DOI] 10.3389/fpubh.2021.778539 PMC 바로가기 [Article Type] Public Health
Prediction of Non-canonical Routes for SARS-CoV-2 Infection in Human Placenta CellsMolecular Biosciences Published on 2021-11-082022-10-31 Journal: Frontiers in Molecular Biosciences [Category] COVID-19, [키워드] ACE2 analyzed canonical Cell cell entry cells changes in coronavirus COVID-19 COVID-19 pandemic CTSL DAAM1 demonstrated DPP4 expressed expression host protein Human identify Infection Interaction mechanism Microarray PAICS Placenta placental predicted prediction Pregnancy Protein Proteins receptor Replication route SARS-CoV-2 SARS-CoV-2 cell SARS-COV-2 infection single-cell These cells TMPRSS2 transcriptional translated transmission of SARS-CoV-2 virus virus entry mediator Zika virus [DOI] 10.3389/fmolb.2021.614728 PMC 바로가기 [Article Type] Molecular Biosciences
Spatio-temporal prediction of the COVID-19 pandemic in US counties: modeling with a deep LSTM neural networkArticle Published on 2021-11-052022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, SARS, [키워드] Accuracy approach compartmental model complex COVID-19 COVID-19 infection COVID-19 pandemic death deep learning Diseases epidemiological granularity heterogeneous IMPROVE Infectious diseases intensity Long Pandemics Population dynamics predict predicted prediction Predictive reduced Result [DOI] 10.1038/s41598-021-01119-3 PMC 바로가기 [Article Type] Article
Prediction and analysis of microRNAs involved in COVID-19 inflammatory processes associated with the NF-kB and JAK/STAT signaling pathwaysNF-kB 및 JAK/STAT 신호 전달 경로와 관련된 COVID-19 염증 과정에 관여하는 microRNA의 예측 및 분석Review Published on 2021-11-012022-09-11 Journal: International immunopharmacology [Category] SARS, 유전자 메커니즘, [키워드] activated Acute inflammation Analysis approved Cityscape connection contribute COVID-19 COVID-19 complications COVID-19 disease COVID-19 patient Critical Diseases Evidence exacerbate feature Host Inflammation Inflammatory inflammatory gene inflammatory genes inflammatory pathway inflammatory pathways inflammatory process Inflammatory response Inflammatory responses Interaction involved JAK-STAT signaling pathway JAK/STAT JAK/STAT signaling pathway manifestation microRNA miR-214 miR-223 miR-9 miRNA miRNAs mitigate morbidity and mortality NF-kB non-coding RNA Non-coding RNAs pandemic pathophysiological mechanism pathway Perturbation perturbations prediction Previous studies previous study Regulation STAT target target gene Target genes therapeutic target therapeutic targets virus [DOI] 10.1016/j.intimp.2021.108071 PMC 바로가기 [Article Type] Review
Autonomic Dysfunction in COVID-19: Early Detection and Prediction Using Heart Rate VariabilityConference abstract Published on 2021-11-012022-10-05 Journal: Journal of the American College of Surgeons [Category] Coronavirus, 치료기술, [키워드] detection heart prediction Rate [DOI] 10.1016/j.jamcollsurg.2021.08.057 [Article Type] Conference abstract
Temporal-Geographical Dispersion of SARS-CoV-2 Spike Glycoprotein Variant Lineages and Their Functional Prediction Using in Silico ApproachResearch Article Published on 2021-10-262022-10-29 Journal: mBio [Category] COVID-19, MERS, SARS, [키워드] in silico prediction Alpha Amino acid amino acid change amino acid variation antigenicity association B.1.1.7 B.1.351 B.1.617 binding affinity binding domain collected Complete conformational change COVID-19 D614G dispersion E484K evade Evolution of SARS-CoV-2 genomic GISAID glycoprotein greater hACE2 Host hypothetical immune immunoinformatics immunological in silico information initiative lineages Mutation mutations N439K N501Y P.1 pandemic Positive selection positive-sense single-stranded RNA predicted prediction Protein residue S protein S protein variant SARS-CoV-2 SARS-CoV-2 variant sequence spike Surveillance the Spike Transmission Vaccines variants variants of concern Variation virus VOCs [DOI] 10.1128/mBio.02687-21 PMC 바로가기 [Article Type] Research Article
Soluble Urokinase Receptor as a Promising Marker for Early Prediction of Outcome in COVID-19 Hospitalized PatientsArticle Published on 2021-10-242022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] acute respiratory distress Admission Algorithm ARDS Biomarker Biomarkers caused Clinical severity complement system Coronavirus disease 2019 Course COVID-19 COVID-19 patients COVID-19 symptomatic patient Critically ill patient death Disease progression evaluated facilitate global pandemic health care systems healthy controls hospital resources Hospitalized ICU intensive care management marker Mild Mild symptom moderate molecular multiple organ failure outcome Patient prediction receptor risk risk stratification in the emergency room SARS-CoV-2 SARS-COV-2 infection Sepsis serum severe cases severe disease severely ill patients spread to suPAR syndrome thrombotic complication urokinase with COVID-19 with mild disease [DOI] 10.3390/jcm10214914 PMC 바로가기 [Article Type] Article
Prediction of pandemic risk for animal-origin coronavirus using a deep learning methodResearch Article Published on 2021-10-242022-10-29 Journal: Infectious Diseases of Poverty [Category] COVID-19, MERS, [키워드] Accuracy AUROC average bats bidirectional characteristic coding region Convolution coronavirus Coronavirus infection cross deep learning Deep Learning Method DNA downloaded evaluate experiment feature Genome genome sequence group humans Infection library mechanism pandemic Pandemic risk pangolins pathogen predict predicted prediction predictive models programming provided reduction Result risk sequence supplementary material the spike protein transfer viral genome viral genomes virus were used whole genome wild animals [DOI] 10.1186/s40249-021-00912-6 PMC 바로가기 [Article Type] Research Article
Can Deep Learning-Based Volumetric Analysis Predict Oxygen Demand Increase in Patients with COVID-19 Pneumonia?Article Published on 2021-10-222022-10-30 Journal: Medicina [Category] COVID-19, MERS, SARS, [키워드] absence Accuracy affected Analysis analyzed AUC automatically calculated Can characteristic Chest computed tomography Chest CT chest imaging coronavirus disease COVID-19 CT scan Data analysis deep deep learning Demand Deterioration evaluate hospital IMPROVE increase initial interquartile range Intervention lung male management material median age medication objective oxygen oxygen demand Patient patients with COVID-19 performed predict prediction Predictive Quantitative analysis radiology resource Result sensitivity significantly higher specificity Treatment Volume were measured with COVID-19 [DOI] 10.3390/medicina57111148 PMC 바로가기 [Article Type] Article