SARS-CoV-2 nucleocapsid – Page 20 – Communicable Diseases Research

Dynamic Changes of Antibodies to SARS-CoV-2 in COVID-19 Patients at Early Stage of Outbreak

발병 초기의 COVID-19 환자에서 SARS-CoV-2에 대한 항체의 동적 변화

Article

Published on 2020-12-012022-09-11
Journal: Virologica Sinica [Category] MERS, SARS, 진단, 치료기술, 치료법,

Viral and Antibody Kinetics of COVID-19 Patients with Different Disease Severities in Acute and Convalescent Phases: A 6-Month Follow-Up Study

급성 및 회복기의 다양한 질병 중증도를 가진 COVID-19 환자의 바이러스 및 항체 동력학: 6개월 추적 연구

Article

Published on 2020-12-012022-09-11
Journal: Virologica Sinica [Category] MERS, SARS, 진단, 치료법,

[키워드] acute phase acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody Antibody Response asymptomatic individual Asymptomatic individuals caused China Clinical features close contact Cohort coronavirus coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) COVID-19 COVID-19 patient Cycle threshold value Delayed disappearance disease severity Economy Health IgG IgM IgM antibodies IgM antibody Infection Kinetics median Mild Most patients nucleocapsid protein occurred onset of symptoms Patient patients with SARS-CoV-2 Protein reduction in respiratory RT-qPCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 nucleocapsid Seroconversion seropositive serum antibody serum antibody response severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) severe disease Spread symptomatic cases Symptomatic patients symptoms onset the antibody the vaccine These data titre Viral Viral load Viral RNA Viral RNA shedding viral shedding
[DOI] 10.1007/s12250-020-00329-9 PMC 바로가기 [Article Type] Article

Expression of SARS-CoV-2 Entry Factors in the Pancreas of Normal Organ Donors and Individuals with COVID-19

정상 장기 기증자와 COVID-19 환자의 췌장에서 SARS-CoV-2 진입 인자의 발현

Article

Published on 2020-12-012022-09-11
Journal: Cell Metabolism [Category] MERS, SARS, 유전자 메커니즘, 진단, 치료법,

[키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Analysis analyzed angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 association CD34 Cell cells coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 dataset demonstrated diabete diabetes Endocrine Ex vivo examined expression Factor FIVE Fluorescence in silico In situ hybridization increased mortality individual individuals with COVID-19 insulin islet lesion microvasculature mRNA level normal pancrea pancreas pancreatic pathogenic performed protein expression respiratory SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 nucleocapsid scRNA-seq Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus thrombotic tissue TMPRSS2 Type 1 diabetes type 2 diabetes unlikely western blotting with COVID-19
[DOI] 10.1016/j.cmet.2020.11.005 PMC 바로가기 [Article Type] Article

A clinical, histopathological and laboratory study of 19 consecutive Italian paediatric patients with chilblain-like lesions: lights and shadows on the relationship with COVID-19 infection

chilblain-like 병변을 가진 19명의 연속 이탈리아 소아 환자에 대한 임상, 조직 병리학 및 실험실 연구: COVID-19 감염과의 관계에 대한 빛과 그림자

Article

Published on 2020-11-012022-09-11
Journal: Journal of the European Academy of Dermatology and [Category] SARS, 유전자 메커니즘, 치료기술, 치료법,

[키워드] Acral anomalies Autoimmune disease Autoimmune diseases basal layer Blood borderline Capillaries Characteristics chilblain children clinical evaluation Coagulation COVID-19 COVID-19 infection COVID-19 pandemic dermis direct immunofluorescence electron microscopy epidermal finger flu-like symptom flu-like symptoms heel histopathological Histopathology hypodermis IgA IgG immunofluorescence increasingly Infection Informed consent Italian Laboratory lesion lesions Major majority mechanism Microscopy mucin Nasopharyngeal swab nucleocapsid protein oedema paediatric patient papillary dermis Pathogenesis pathological finding Patient patients perivascular positive Protein recruited reported RT-PCR S1 domain SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 nucleocapsid SARS-CoV-2 spike protein selected serology serology testing skin lesion skin lesions skin manifestation Spike protein Swab thrombi vessel with COVID-19
[DOI] 10.1111/jdv.16682 PMC 바로가기 [Article Type] Article

Perniosis during the COVID-19 pandemic: Negative anti-SARS-CoV-2 immunohistochemistry in six patients and comparison to perniosis before the emergence of SARS-CoV-2

COVID-19 대유행 중 Perniosis: 6명의 환자에서 음성 항-SARS-CoV-2 면역조직화학 및 SARS-CoV-2 출현 전의 perniosis와 비교

Comparative Study

Published on 2020-11-012022-09-11
Journal: Journal of cutaneous pathology [Category] SARS, 치료법,

Clinical Evaluation of BD Veritor SARS-CoV-2 Point-of-Care Test Performance Compared to PCR-Based Testing and versus the Sofia 2 SARS Antigen Point-of-Care Test

PCR 기반 테스트 및 Sofia 2 SARS 항원 현장 진단과 비교한 BD Veritor SARS-CoV-2 현장 진료 테스트 성능의 임상 평가

Comparative Study

Published on 2020-10-062022-09-10
Journal: Journal of Clinical Microbiology [Category] MERS, SARS, 진단, 치료기술, 치료법,

[키워드] age Analysis Antigen clinical COVID-19 COVID-19 symptoms COVID-19 testing criteria demonstrated detection determine Emergency use authorization EUA evaluated FDA FIVE immunoassay individuals with COVID-19 Lyra nasal nasal swab nasal swabs nasopharyngeal oropharyngeal specimen participant PCR PCR assay performance point-of-care point-of-care test positive positive result Primary outcomes ranged Rapid SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 detection SARS-CoV-2 nucleocapsid SARS-CoV-2 PCR Sofia 2 test specimen Symptom symptom onset Symptoms System Test Testing Veritor test with COVID-19
[DOI] 10.1128/JCM.02338-20 PMC 바로가기 [Article Type] Comparative Study

Fibrotic progression and radiologic correlation in matched lung samples from COVID-19 post-mortems

COVID-19 사후 부검에서 일치하는 폐 샘플의 섬유화 진행 및 방사선학적 상관관계

Original Article

Published on 2020-09-282022-09-10
Journal: Virchows Archiv [Category] SARS, 치료법,

[키워드] alveolar alveolar damage Analysis approach category changes in Computed tomography consolidation correlated correlation COVID-19 COVID-19 patient COVID-19 patients death died Diffuse alveolar damage disease eight enrolled Evolution Features fibrosis Follow-up ground-glass opacity histologic histologic finding histologic findings Histopathologic analysis illness duration immunohistochemistry implication information Intubated lesion lesions lobes lung Lung fibrosis lung lesions lung lobe lung tissue lung tissues mechanically ventilated median pathologic pathology Patient positive Post-mortem progression Protein radiologic Radiologic patterns SARS-CoV-2 nucleocapsid SARS-CoV-2-positive patients tomography transbronchial Transbronchial lung cryobiopsy Treatment two patients was performed
[DOI] 10.1007/s00428-020-02934-1 PMC 바로가기 [Article Type] Original Article

Heterogeneous antibodies against SARS-CoV-2 spike receptor binding domain and nucleocapsid with implications for COVID-19 immunity

Research Article

Published on 2020-09-172022-10-30
Journal: JCI Insight [Category] COVID-19, SARS,

[키워드] acute respiratory syndrome Adaptive immunity antibody Antibody detection Antibody Response binding antibody circulating antibody collected coronavirus correlation COVID-19 COVID-19 immunity detection ELISA exhibited Generation Health healthy IgG antibody immune response Immunity immunology implication individual moderate N-protein neutralize Neutralizing antibodies neutralizing capacity nucleocapsid pandemic patients positive Protein Quantitative Receptor binding domain reverse transcription S-RBD SARS-CoV-2 SARS-CoV-2 nucleocapsid SARS-CoV-2 spike sera Seroconversion serological serology assay serology testing serum sample Spike protein the SARS-CoV-2 Viral protein virus infection
[DOI] 10.1172/jci.insight.142386 PMC 바로가기 [Article Type] Research Article

Structural characterization of the C-terminal domain of SARS-CoV-2 nucleocapsid protein

Research

Published on 2020-08-062022-10-30
Journal: Molecular Biomedicine [Category] COVID-19,

Kinetics of SARS-CoV-2 specific IgM and IgG responses in COVID-19 patients

Research Article

Published on 2020-05-132022-10-31
Journal: Emerging Microbes & Infections [Category] COVID-19, MERS, SARS,

[키워드] Antibody testing blood sample C-reactive protein C-reactive protein (CRP can be used caused collected Course COVID-19 COVID-19 patient Critical decrease diagnosis of COVID-19 ELISA global public health help ICU ICU patient identify IgG IgG response IgM IgM and IgG increase in intensive care investigated Kinetics longitudinal analysis non-ICU patient non-ICU patients Patient patients positively correlated predict Prognosis Protein reached responses against S protein SARS-CoV-2 SARS-CoV-2 infected patient SARS-COV-2 infection SARS-CoV-2 nucleocapsid significantly higher specific IgM symptom onset the disease
[DOI] 10.1080/22221751.2020.1762515 PMC 바로가기 [Article Type] Research Article