SARS-CoV-2 does not have a strong effect on the nasopharyngeal microbial compositionArticle Published on 2021-04-262022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, SARS, [키워드] Amplicon sequencing Analysis conditions Corona coronavirus disease COVID-19 disease evaluate Evidence Health individuals Interaction lab microbial microbial community Microbiome nasopharyngeal nasopharyngeal sample nasopharyngeal swab sample nasopharynx PCR positive COVID-19 respiratory respiratory tract SARS-CoV-2 SARS-COV-2 infection severity significant effect Spread subject subjects submitted the SARS-CoV-2 Variation viral disease viruses [DOI] 10.1038/s41598-021-88536-6 PMC 바로가기 [Article Type] Article
Detection of SARS‐CoV‐2 in respiratory samples from cats in the UK associated with human‐to‐cat transmission사람에서 고양이로의 전염과 관련된 영국 고양이의 호흡기 샘플에서 SARS-CoV-2 검출Original Research Published on 2021-04-222022-09-10 Journal: The Veterinary Record [Category] Fulltext, MERS, SARS, 조류인플루엔자, 치료기술, 치료법, [키워드] Analysis Antigen cats collected conjunctivitis coronavirus COVID‐19 COVID‐19 detection eight Evidence evidence of FIVE immunofluorescence infect lung tissue Mild MONITOR mutations New coronavirus nine nucleocapsid antigen nucleotide objective occurred oropharyngeal swab oropharyngeal swabs pandemic positive quantitative PCR reference sequence respiratory Respiratory disease respiratory pathogen respiratory sample Result reverse transcriptase reverse zoonosis rhinitis RNA SARS‐CoV‐2 SARS‐CoV‐2 infection SARS‐CoV‐2 sequence Sequencing severe respiratory disease Single nucleotide polymorphism single nucleotide polymorphisms SNP SNPs submitted tested tissue tissue samples transcriptase Transmission Viral viral genome Viral RNA virus was tested [DOI] 10.1002/vetr.247 PMC 바로가기 [Article Type] Original Research
Global dynamics of SARS-CoV-2 clades and their relation to COVID-19 epidemiologySARS-CoV-2 분기군의 글로벌 역학 및 COVID-19 역학과의 관계Article Published on 2021-04-192022-09-10 Journal: Scientific Reports [Category] MERS, SARS, 변종, 진단, 치료법, [키워드] age Analysis analyzed asymptomatic patient asymptomatic patients children clade clades country COVID-19 COVID-19 cases D614G D614G mutation Deceased distributions Epidemiology Evidence Evolution of SARS-CoV-2 Evolutionary developmental biology expansion female Female patients followed by Gender genomic genomic variation genomic variations GISAID database group increase Infectious diseases male Metadata Mild disease Mortality novel SARS-CoV-2 virus Prevalence prevalent SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 virus significantly higher statistical submitted virulence with mild disease [DOI] 10.1038/s41598-021-87713-x PMC 바로가기 [Article Type] Article
A randomised, double-blind, placebo-controlled, pilot trial of intravenous plasma purified alpha-1 antitrypsin for SARS-CoV-2-induced Acute Respiratory Distress Syndrome: a structured summary of a study protocol for a randomised, controlled trialSARS-CoV-2 유발 급성 호흡곤란 증후군에 대한 정맥내 혈장 정제 알파-1 항트립신의 무작위 이중 맹검 위약 대조 파일럿 시험: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-04-192022-09-10 Journal: Trials [Category] 임상, [키워드] 24 hours active malignancy acute kidney Acute kidney injury acute respiratory distress syndrome addition Administered administration adverse event adverse events AEs age Alpha alpha-1 antitrypsin Amendment Anti-viral Antibiotics anticipated antitrypsin antivirals approval approved ARDS ARMS authority bacterial pneumonia baseline Berlin criteria blinded to treatment Blinding BMI body weight Cancer changes in Child-Pugh score chloride Chronic kidney disease chronic liver disease circulating class clinical Clinical outcome clinical trial Combination commenced Committee comparator Complete conducted Consent Controlled trial correction COVID-19 Culture cytokine level cytokine levels Data collection defined determine Diagnosis diagnosis of ARDS dialysis dissemination DNAR double-blind Echocardiogram Effect Effectiveness elapsed element ELISA enrolled EudraCT excluded exclusion exclusion criteria facilitate Follow-up followed by for inclusion group Health Products regulatory Authority hospital Hospital admission hypertension ICU IgA deficiency IL-10 IL-1β IL-6 IL-8 incidence inclusion criteria individual information intensive care unit intensive care units interim analysis interleukin interleukin-10 interleukin-1β interleukin-6 interleukin-8 interpreter Intervention intravenous intravenous infusion intravenously invasive investigational medicinal product investigator Ireland Kidney disease Laboratory laboratory-confirmed life Local maintain major trauma malignancy mandatory marker mechanical ventilation Microscopy moderate moderate to severe Mortality Non-invasive non-invasive mechanical ventilation non-invasive ventilation number objective occur Organ failure outcome outcome measure PaO participant Patient patient recruitment patients with moderate PCR-confirmed Phase 2 physician Placebo placebo-controlled plasma plasma analysis plasma concentration plasma concentrations pregnant preparation product protocol provided Pulmonary embolism pulmonary hypertension purified Radiographic randomisation randomisation list randomised randomised controlled trial rationale readmission REC receiving receptor recruited recruitment reduce Regulatory removal renal renal replacement therapy replacement therapy reported required Research Research Ethics Research Ethics Committee research nurse research nurses respiratory respiratory distress Respiratory distress syndrome resulting Resuscitation SAE SAEs Sample size SARS-CoV-2 secondary secondary bacterial pneumonia Secondary objective Secondary objectives Secondary outcomes secretion Sequential Organ Failure Assessment Serious Adverse Event Serious Adverse Events severe ARDS Shock single dose skin cancer Sodium chloride SOFA Standard statistician stratified study participation Study protocol subject submitted supplementary material Support sustained TNF TNF-α Tolerability trauma Treatment treatment allocation Trial trial protocol Trial registration vasopressors ventilator verbal Version Volume website WHO Withdrawal writing [DOI] 10.1186/s13063-021-05254-0 PMC 바로가기 [Article Type] Letter
Analysis of Thrombotic Adverse Reactions of COVID-19 AstraZeneca Vaccine Reported to EudraVigilance DatabaseArticle Published on 2021-04-162022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] Adverse Adverse drug reaction adverse event adverse events Adverse reaction Adverse reactions Analysis assessment AstraZeneca benefit Blood Characteristics Committee Comorbidities Conducting COVID-19 database death effective EMA European country European Medicines Agency event fatality group identify pandemic pharmacovigilance reaction Research retrospective Safe specificity submitted the vaccine thrombosis thrombotic vaccination Vaccine Vaccines World Health Organization’ [DOI] 10.3390/vaccines9040393 PMC 바로가기 [Article Type] Article
Neurological presentations of COVID-19: Findings from the Spanish Society of Neurology neuroCOVID-19 registryObservational Study Published on 2021-04-152022-10-05 Journal: Journal of the neurological sciences [Category] SARS, 임상, [키워드] age Altered Altered mental status Analysis Anosmia categories cerebrospinal fluid Combination Course COVID-19 delirium differential diagnoses epilepsy finding General symptom greater headache Headache disorders Laboratory Manifestations Mental multicentre myalgia neurological manifestation Neurological symptom Neurological symptoms NEUROLOGY occur occurred Onset onset of symptom Patient patients performed physician positive result proportion radiological registry reported SARS-CoV-2 Seizure severity Society Spanish Standard deviation stroke submitted Symptom Symptoms symptoms appeared the disease was performed was recorded women [DOI] 10.1016/j.jns.2020.117283 PMC 바로가기 [Article Type] Observational Study
Monitoring and evaluation of COVID-19 response in the WHO African region: challenges and lessons learnedWHO 아프리카 지역의 COVID-19 대응 모니터링 및 평가: 도전과제 및 교훈Short Paper Published on 2021-04-142022-09-11 Journal: Epidemiology and Infection [Category] MERS, SARS, 치료기술, [키워드] African African region country COVID-19 COVID-19 pandemic Early detection effort epidemiological evaluate event health emergencies health emergency identify Investment Measures MONITOR monitoring monitoring and evaluation National outcome profiles public health public health emergency selected submitted Support Task Force the WHO threat Threats to define were used WHO [DOI] 10.1017/S0950268821000807 PMC 바로가기 [Article Type] Short Paper
Clinical and radiological imaging as prognostic predictors in COVID-19 patientsResearch Published on 2021-04-092022-10-31 Journal: The Egyptian Journal of Radiology and Nuclear Medicine [Category] COVID-19, [키워드] age Analysis Anterior AUC Chest CT clinical clinical picture COVID-19 COVID-19 pandemic COVID-19 patient Cutoff described disease distribution enrolled evaluated extension Fatal outcome feature ground-glass opacity group Infection Laboratory laboratory-confirmed lower lobe male moderate Mortality mortality rate Novel coronavirus outcome oxygen saturation pandemic Patient performed Pneumonia predictor predominant Prognosis prognostic prospective observational study radiological Result ROC Curve severity significant negative correlation significantly Stage statistically significant submitted [DOI] 10.1186/s43055-021-00470-9 PMC 바로가기 [Article Type] Research
Effect of smartphone app on post-traumatic stress disorder in COVID-19 convalescent patients A protocol for systematic review and meta-analysis스마트폰 앱이 코로나19 회복기 환자의 외상 후 스트레스 장애에 미치는 영향 체계적인 검토 및 메타 분석을 위한 프로토콜Meta-Analysis Published on 2021-04-092022-09-10 Journal: Medicine [Category] MERS, SARS, 임상, [키워드] Affect affecting Anxiety Central nervous system conducted Controlled Convalescent patients coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 convalescent patient COVID-19 convalescent patients database Depression Effect effective intervention evaluate evaluate the effect Evidence exclusion criteria Guidance Health help Hospitalization inception Inclusion inclusion and exclusion criteria Intervention investigator life Meta-analysis meta-analysis and systematic review outbreak Patient peer-reviewed physically Post-traumatic stress disorder Prevalence Prevent protocol Psychological PTSD reduce registration number rehabilitation risk risk of bia searched smartphone app submitted systematic review therapy was performed Web of Science [DOI] 10.1097/MD.0000000000025479 PMC 바로가기 [Article Type] Meta-Analysis
The perception of COVID-19 among Italian dental patients: an orthodontic point of viewResearch Published on 2021-04-072022-10-29 Journal: Progress in Orthodontics [Category] COVID-19, MERS, SARS, [키워드] Affect age analyzed chi-square test COVID-19 COVID-19 infection COVID-19 outbreak Dental patient dental practice dentist distress Frequency Gender greater increase in Italian lockdown Logistic regression analysis MOST Orthodontics pandemic participant Patient Perceived risk Prevalence questionnaire Result risk slight increase subject submitted survey temporomandibular disorder thought TMD TMD pain Treatment women [DOI] 10.1186/s40510-021-00355-7 PMC 바로가기 [Article Type] Research