Obesity, chronic disease, age, and in-hospital mortality in patients with covid-19: analysis of ISARIC clinical characterisation protocol UK cohortResearch Published on 2021-07-312022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, SARS, [키워드] Admission age Ageing Analysis Cancer categories category CCP-UK characterisation chronic chronic cardiac disease chronic disease Chronic kidney disease chronic pulmonary disease clinical clinical decision clinician coded Cohort Combination COVID-19 COVID-19 mortality deaths diabete disease examined groups hazard ratio highest hospital Hospital admission hypertension implication In-hospital In-hospital death in-hospital mortality Interaction ISARIC medical records men obesity outcome outcomes Patient Prevalence prevalent protocol Public health interventions remained respiratory Result risk risk factor Sex supplementary material survival used data Vaccination strategy was determined with COVID-19 women [DOI] 10.1186/s12879-021-06466-0 PMC 바로가기 [Article Type] Research
Antibody responses after first and second Covid-19 vaccination in patients with chronic lymphocytic leukaemia만성 림프구 백혈병 환자에서 제 1 및 제 2 코비드 -19 백신 접종 후 항체 반응Clinical Trial Published on 2021-07-302022-08-09 Journal: Blood Cancer Journal [Category] 임상, 진단, [키워드] Adaptive immunity Antibody Response Antibody responses Antibody titre antibody titres B-cell blood sample Blood samples BNT162b2 BNT162b2 mRNA vaccine booster vaccines BTK inhibitor BTK inhibitors ChAdOx1 Chronic lymphocytic leukaemia clinical risk CLL COVID-19 vaccines detectable dried blood spot Dried blood spots extended interval failure Filter Paper generate healthy donor healthy donors IgA deficiency Immunosuppression Multivariate analysis offer Patient profile remained SARS-COV-2 infection second vaccination Severe infection spike-specific antibody response Spike-specific antibody responses Support the antibody response the patient titre titres Translational research Treatment utility vaccination Vaccination strategy Vaccine venepuncture [DOI] 10.1038/s41408-021-00528-x PMC 바로가기 [Article Type] Clinical Trial
The variants question: What is the problem?변형 질문: 문제가 무엇입니까?Review Published on 2021-07-282022-09-10 Journal: Journal of medical virology [Category] SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 advance circulating coronavirus Course determine effort Epidemiology Evolution genetic diversity Genetic variant Genome genomes Highlights immune intervention strategies magnitude Mutation over pandemic Protein public health respiratory SARS‐CoV‐2 SARS‐CoV‐2 genome SARS‐CoV‐2 genomes SARS‐CoV‐2 Sequencing severe acute respiratory syndrome Coronavirus Spike protein Spread suggested the Spike Transmission Vaccination strategy Vaccine variant variants virulence virus VoC VOCs VOI VOIs widespread Wuhan Wuhan, China [DOI] 10.1002/jmv.27196 PMC 바로가기 [Article Type] Review
Leveraging Artificial Intelligence and Big Data to Optimize COVID-19 Clinical Public Health and Vaccination Roll-Out Strategies in Africa인공 지능과 빅 데이터를 활용하여 아프리카의 COVID-19 임상 공중 보건 및 백신 출시 전략 최적화Editorial Published on 2021-07-262022-09-10 Journal: International Journal of Environmental Research an [Category] SARS, 변종, [키워드] Africa African amplify Analysis artificial artificial intelligence big data clinical complexity country COVID-19 develop economic costs effective Effectiveness equity Health Innovation intelligence National pandemic parameters Public public health Strategy the vaccine Vaccination strategies Vaccination strategy Vaccine vaccine roll-out variants variants of concern VoC while [DOI] 10.3390/ijerph18157890 PMC 바로가기 [Article Type] Editorial
The synchronicity of COVID-19 disparities: Statewide epidemiologic trends in SARS-CoV-2 morbidity, hospitalization, and mortality among racial minorities and in rural AmericaResearch Article Published on 2021-07-232022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] adjust adjusted America ANOVA calculated change Cohort conducted COVID-19 death demographic group disease Electronic health records greater group Health highest Hospitalization Initially measure morbidity morbidity and mortality Mortality mortality rate notable observational study pandemic Population populations PROTECT public health Racial rates of infection Result SARS-CoV-2 SARS-COV-2 infection single center surpassed tested Vaccination strategy [DOI] 10.1371/journal.pone.0255063 PMC 바로가기 [Article Type] Research Article
Antibody titres decline 3-month post-vaccination with BNT162b2항체 역가는 BNT162b2 백신 접종 3개월 후 감소Multicenter Study Published on 2021-07-222022-09-10 Journal: Emerging Microbes & Infections [Category] SARS, 진단, 치료법, [키워드] 95% CI All participants antibody Antibody Response baseline Blood BNT162b2 BNT162b2 mRNA BNT162b2 mRNA COVID-19 vaccine collected Concentration COVID-19 COVID-19 vaccine different time points dose first dose hcp Healthcare professional healthcare professionals humoral Humoral response individual Kinetics kinetics of antibody maximum concentration mRNA vaccine multicentre nucleocapsid Participants Receptor binding domain remained reported robust S1 subunit Sample SARS-CoV-2 SARS-CoV-2 nucleocapsid seronegative seronegative participants seropositive seropositive participants Spike protein subject subjects the antibody response the S1 subunit the SARS-CoV-2 the spike protein titre Vaccination strategy vaccine dose were measured [DOI] 10.1080/22221751.2021.1953403 PMC 바로가기 [Article Type] Multicenter Study
Severe COVID-19 by SARS-CoV-2 Lineage B.1.1.7 in Vaccinated Solid-Organ Transplant Recipients: New Preventive Strategies Needed to Protect Immunocompromised PatientsArticle Published on 2021-07-212022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] All the patient B.1.1.7 B.1.1.7 lineage BNT162b2 mRNA vaccine booster caused COVID-19 COVID-19 vaccination COVID-19 vaccine Diagnosis dose Efficacy high risk Hospitalized Immunocompromised patient Immunocompromised patients Italy kidney transplant recipients Lineage molecular mRNA Mutation Nasopharyngeal swab New one patient Precaution prolonged viral shedding Protecting Real-time PCR recipient recipients reported SARS-CoV-2 SARS-CoV-2 B.1.1.7 SARS-CoV-2 gene SARS-COV-2 infection severe COVID-19 solid-organ transplant recipients SOT SOT patient Spike protein Strategy Transplant Two patient vaccination Vaccination strategy Vaccine Viral load whole-genome sequencing [DOI] 10.3390/vaccines9080806 PMC 바로가기 [Article Type] Article
Modeling vaccination strategies in an Excel spreadsheet: Increasing the rate of vaccination is more effective than increasing the vaccination coverage for containing COVID-19Research Article Published on 2021-07-192022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] addition benefit Coverage COVID-19 demographics distribution effective Efficacy epidemiological Government Health implementation include Increasing indicate investigated Local modeling pandemic Pandemics parameter predict progression quarantine social distancing Social distancing measure subject vaccination Vaccination strategies Vaccination strategy Vaccine widespread [DOI] 10.1371/journal.pone.0254430 PMC 바로가기 [Article Type] Research Article
Integrated vaccination and non-pharmaceutical interventions based strategies in Ontario, Canada, as a case study: a mathematical modelling studyLife Sciences–Mathematics interface Published on 2021-07-142022-10-30 Journal: Journal of the Royal Society Interface [Category] COVID-19, SARS, [키워드] benefit Canada Combination concerning coronavirus disease COVID-19 COVID-19 case COVID-19 pandemic cumulative effective epidemiological helping immunization Intervention local public health Mathematical modelling Measures Non-pharmaceutical interventions occur Ontario Outbreaks public health public health measure Reproduction number risk vaccination Vaccination strategy Vaccine vaccine and immunization campaign was used [DOI] 10.1098/rsif.2021.0009 PMC 바로가기 [Article Type] Life Sciences–Mathematics interface
Investigating associations between COVID-19 mortality and population-level health and socioeconomic indicators in the United States: A modeling studyResearch Article Published on 2021-07-132022-10-29 Journal: PLoS Medicine [Category] COVID-19, [키워드] Adjusting age association autocorrelation calculated can be used Characteristics Chronic kidney disease collinearity COVID-19 COVID-19 mortality criteria death deaths dependent on disease Effect estimate estimates explain explained Health health condition highest include increase in Interaction limitation Mortality mortality rate National occur outbreak outcome outcomes Population predicted predictor predictors Presence Prevalence proportion R 2 reduce researcher risk risk of COVID-19 SAR selected Significant Strong Structure study population the United State The United States utility Vaccination strategy Vaccine Vaccines Variability were used with COVID-19 [DOI] 10.1371/journal.pmed.1003693 PMC 바로가기 [Article Type] Research Article