Side-By-Side Evaluation of Three Commercial ELISAs for the Quantification of SARS-CoV-2 IgG AntibodiesSARS-CoV-2 IgG 항체의 정량화를 위한 3가지 상용 ELISA의 병행 평가Article Published on 2022-03-112022-09-12 Journal: Viruses [Category] MERS, SARS, 진단, [키워드] anti-SARS-CoV-2 antibodies antibody unit BAU calibrated comparability COVID-19 creating ELISA ELISA kit examined Germany highlight IgG IgG ELISA Immunoglobulin International Interpretation Kiel Lubeck neutralization tests quantification Quantitative SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 IgG antibodies serological test serum sample tested the WHO Topic vaccinated individual virus neutralization test WHO [DOI] 10.3390/v14030577 PMC 바로가기 [Article Type] Article
Uptake of the multi-arm multi-stage (MAMS) adaptive platform approach: a trial-registry review of late-phase randomised clinical trialsRandomized Controlled Trial Published on 2022-03-102022-10-05 Journal: BMJ Open [Category] Coronavirus, 임상, [키워드] accelerated adaptive African approach Arm ARMS assist Cancer Characteristics clinical clinical pharmacology clinical trial clinical trials Cochrane Library Controlled COVID-19 defined disease examined global health highlight Infectious disease Infectious diseases interim analysis Intervention intervention arms knowledge library majority medical condition medication medications multi-arm New number oncology Pan platform Platform trial PROSPERO public health randomised randomised clinical trial recruitment Registered registry Research stages Standard treatment interventions Trial trials Two-arm uptake was performed WHO [DOI] 10.1136/bmjopen-2021-055615 PMC 바로가기 [Article Type] Randomized Controlled Trial
From delta to Omicron: S1-RBD/S2 mutation/deletion equilibrium in SARS-CoV-2 defined variants델타에서 오미크론으로: SARS-CoV-2 정의된 변이체에서 S1-RBD/S2 돌연변이/결실 평형Review Published on 2022-03-102022-09-11 Journal: Gene [Category] MERS, SARS, 변종, 유전자 메커니즘, 진단, [키워드] acute respiratory syndrome Affect affected Alpha alteration beta-CoV beta-CoVs Corona COVID-19 defined domain elevated functional Genome glycoprotein involved Lineage mechanism MERS-CoV modify mutations national health system new SARS-CoV-2 omicron Phylogenetic RBD Re-infection respiratory RNA RNA sequence RNA sequences S1/S2 SARS-CoV SARS-CoV-2 SARS-CoV-2 S SARS-CoV-2 virus Severe acute respiratory syndrome similarity spike subunit Transmissibility unique variant variants virion virus virus-cell membrane fusion WHO [DOI] 10.1016/j.gene.2021.146134 PMC 바로가기 [Article Type] Review
Neutralisation Hierarchy of SARS-CoV-2 Variants of Concern Using Standardised, Quantitative Neutralisation Assays Reveals a Correlation With Disease Severity; Towards Deciphering Protective Antibody Thresholds표준화된 정량적 중화 분석을 사용하여 우려되는 SARS-CoV-2 변이체의 중화 계층은 질병 심각도와의 상관관계를 보여줍니다. 보호항체 역치를 해독하기 위해Article Published on 2022-03-072022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 변종, 진단, [키워드] (Alpha) (Beta) 20/136 Alpha anti-SARS-CoV-2 anti-SARS-CoV-2 immunoglobulin antibody Antibody titre Asymptomatic B.1.1.7 B.1.351 B.1.617.1 B.1.617.2 Beta Cohort concern convalescent sera correlates of protection (CoP) COVID-19 Critical care Delta did not produce disease disease severity First wave Gamma HCW HCWs healthcare worker Healthcare workers hierarchy Immunoglobulin individual International international standard international units IU/mL K417N Laboratory laboratory findings mild case mild cases National neutralisation neutralise P.1 Pseudotyped virus pursuit reduction in SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants sera severe COVID-19 Standard Symptoms the WHO threshold titre titres to define unit utilised variants variants of concern variants of interest VoC VOCs WHO World Health Organisation [DOI] 10.3389/fimmu.2022.773982 PMC 바로가기 [Article Type] Article
Intelligent system based comparative analysis study of SARS-CoV-2 spike protein and antigenic proteins in different types of vaccinesResearch Published on 2022-03-072022-10-28 Journal: Beni-Suef University Journal of Basic and Applied Sciences [Category] COVID-19, [키워드] Amino acid Analysis And PCV10 antigenic protein caused China coding Combination comparison coronavirus coronavirus 2 Coronavirus disease 2019 correlation country COVID-19 COVID-19 virus death deaths disease explain Genome Genome signature Genomic coding techniques hepatitis B HIB humans immune response implicated in silico infect intestinal investigated less measles membrane fusion MMR Novel coronavirus pandemic Poliovirus PROTECT protective effect Protein receptor respiratory respiratory infections Result RNA virus rubella S gene S protein SARS-CoV-2 SARS-CoV-2 spike protein sequence severity spike Spread symptomatic case the Coronaviridae the SARS-CoV-2 genome Vaccine Vaccines Variation WHO World Health Organization [DOI] 10.1186/s43088-022-00216-0 PMC 바로가기 [Article Type] Research
Various vaccine platforms in the field of COVID-19Review Published on 2022-03-072022-10-28 Journal: Beni-Suef University Journal of Basic and Applied Sciences [Category] COVID-19, [키워드] Alpha anticipated caused China Corona virus COVID-19 COVID-19 vaccine Critical determine develop dose effective geographical region greater Health help highest immune system Immunity immunization IMPROVE Infection LAV Medicines Mortality mutant strain Mutation occurred omicron Oxygen therapy pandemic potential barrier Prevent progressed Protective RBD recent Research risk SARS-CoV-2 South Spread Symptom the epidemic treat vaccine platform Vaccines variant variety viral infectious disease virus variant WHO Wuhan [DOI] 10.1186/s43088-022-00215-1 PMC 바로가기 [Article Type] Review
Estimating the global and regional burden of meningitis in children caused by Haemophilus influenzae type b: A systematic review and meta-analysisArticles Published on 2022-03-052022-10-31 Journal: Journal of Global Health [Category] Coronavirus, MERS, SARS, [키워드] 95% confidence interval AFR African Asian assessment assessment criteria caused cerebrospinal fluid CFR children continuous surveillance coronavirus disease country COVID-19 COVID-19 pandemic Culture deaths development disease Diseases Eastern Mediterranean Region eliminated EMR estimates European evaluated Haemophilus influenzae heart heterogeneity highest incidence incidence rate information invasive linear mixed model lowest management Meningitis Meta-analysis MONITOR Mortality NHLBI performed Prevalence public health Quality recent Region reported Result searched standard error statistically stratified study period subgroup analysis systematic review Type vaccination Vaccine was used were assessed WHO World Health Organisation [DOI] 10.7189/jogh.12.04014 PMC 바로가기 [Article Type] Articles
SARS-CoV-2 origin, myths and diagnostic technology developmentsReview Published on 2022-03-042022-11-01 Journal: The Egyptian Journal of Medical Human Genetics [Category] COVID-19, [키워드] accelerated approach assays baseline Body caused China COVID-19 CRISPR Culture Diagnosis diagnostic Diagnostic method diagnostics drug resistance Effect ELISA epidemiological evaluated Factor False negative Future Genome Healthcare systems implication information Intervention isothermal amplification knowledge Laboratory LAMP less management morbidity myth pandemic paucity of data profile provided reducing repeated reported RT-PCR SARS-CoV-2 SARS-CoV-2 virus sensitivity specificity targeted therapy the patient TMA Treatment virus virus genome WHO World Health Organization Zika virus [DOI] 10.1186/s43042-022-00255-3 PMC 바로가기 [Article Type] Review
Successful Reversal of the 2020 Covid-19 Response Induced Collateral Damage on Malaria Control in Saudi ArabiaConference abstract Published on 2022-03-012022-10-05 Journal: International Journal of Infectious Diseases [Category] 유전자 메커니즘, [키워드] activities analyzed Anophele Can Collateral Control correlated Coverage COVID-19 COVID-19 pandemic damage Environment Epidemic indicated induced lockdown malaria malaria control management material one health outbreak pandemic Patient patients treated platform positive post intervention post-intervention precipitated Program protocol provided recorded reduction reductions in reflected residual response Result reversal Saudi Arabia Support Surveillance Transmission treated water WHO [DOI] 10.1016/j.ijid.2021.12.288 [Article Type] Conference abstract
WHO International Standard for evaluation of the antibody response to COVID-19 vaccines: call for urgent action by the scientific communityPersonal View Published on 2022-03-012022-10-31 Journal: The Lancet. Microbe [Category] COVID-19, MERS, SARS, [키워드] anti-SARS-CoV-2 Biological calibrated calibration Committee conducted contribute COVID-19 COVID-19 vaccines diagnostic expected expert facilitate immune response Immunoglobulin National neutralising antibody Panel provide public health reagents reference SARS-CoV-2 Scientific community Standard the antibody response the WHO therapeutic View WHO [DOI] 10.1016/S2666-5247(21)00266-4 PMC 바로가기 [Article Type] Personal View