Proteomic profiling of lung diffusion impairment in the recovery stage of SARS-CoV-2-induced ARDSSARS-CoV-2 유발 ARDS의 회복 단계에서 폐 확산 장애의 단백질체 프로파일링Article Published on 2022-05-012022-09-11 Journal: Clinical and Translational Medicine [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] ARDS diffusion impairment lung [DOI] 10.1002/ctm2.838 PMC 바로가기 [Article Type] Article
Sleep health and the circadian rest-activity pattern four months after COVID-19Observational Study Published on 2022-04-292022-10-05 Journal: Revista da Sociedade Brasileira de Medicina Tropic [Category] 임상, [키워드] acute phase alteration ANOVA ARDS change changes in chi-square test COVID-19 COVID-19 group COVID-19 patient cross-sectional difference Efficiency English evaluated Health Hospitalization index Insomnia Insomnia Severity Index mechanical ventilation Mental mental health Mild Moderate COVID-19 obstructive sleep apnea pacientes com COVID-19 Patient Pittsburgh Prevalence Prospective Study prospectivo Quality Quality of life questionnaire Satisfaction severe COVID-19 severity Sleep sleep apnea sleep disorder sleep quality Symptoms the disease three group three groups was increased [DOI] 10.36416/1806-3756/e20210398 PMC 바로가기 [Article Type] Observational Study
Circulating microRNA profiling is altered in the acute respiratory distress syndrome related to SARS-CoV-2 infection Research Published on 2022-04-282022-10-05 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 바이오마커, [키워드] acute inflammatory response acute respiratory distress analyzed ARDS cellular COVID-19 COVID-19 patients Cytokine storm Cytokine storm syndrome dataset differentially expressed miRNA enriched pathway fat cell fold Gene Expression hallmark immune immune dysregulation in silico analysis independent Infection Inflammatory response Inflammatory responses intensive care involved mechanical ventilation microRNA miRNA miRNAs parameter pathway enrichment Patient patient groups physiological Prognosis qPCR receptor protein Regulation resulting SARS-COV-2 infection Sequencing significantly Symptom syndrome transmembrane was performed with COVID-19 [DOI] 10.1038/s41598-022-10738-3 [Article Type] Research
Not Only COVID-19: Involvement of Multiple Chemosensory Systems in Human DiseasesCOVID-19 뿐만 아니라: 인간 질병에 여러 화학 감각 시스템의 관련Review Published on 2022-04-252022-09-12 Journal: Frontiers in neural circuits [Category] 진단, [키워드] affected ARDS Brain Cancer carotid carotid bodies Cell cells chemesthesis chemoreceptor chemosensation chemosensory condition consequence Course COVID-19 COVID-19 patients diabetes diarrhea Effect Endocrine enterochromaffin cells events example explained functions Human hypertension hypoxia immune systems impairment Involvement metabolism molecular feature MONITOR mortality rate much higher Multiple neuroendocrine non-infectious disease Olfaction olfactory parameter pathology patients Pneumonia Prognosis pulmonary neuroendocrine cells receiving receptor regulate reported respiratory silent solitary chemoreceptor cells Stress Structure survival Symptom System Taste the disease underlie visceral worsening [DOI] 10.3389/fncir.2022.862005 PMC 바로가기 [Article Type] Review
Diagnostic Accuracy of Chest Digital Tomosynthesis in Patients Recovering after COVID-19 PneumoniaCOVID-19 폐렴 후 회복 중인 환자의 흉부 디지털 단층 합성의 진단 정확도Observational Study Published on 2022-04-242022-09-11 Journal: Tomography [Category] SARS, 임상, 치료기술, [키워드] Accuracy Admission age air bronchogram analyzed approval ARDS average Average dose Berlin criteria bronchogram calculated carried changes in Chest chest digital tomosynthesis chest imaging chest X-ray Complete Computed tomography consolidation COVID-19 COVID-19 pneumonia criteria CT scan CXR Diagnosis diagnostic Diagnostic accuracy dose DTS emergency department Follow-up followed by GGO GGOs Ground-glass opacities ground-glass opacity hospital inclusion criteria Indicator interstitial linear Local lung Lung disease material Nasopharyngeal swab nasopharyngeal swabs observational study Patient patients performed Pneumonia positive RT-PCR R statistical software radiologist recognizing retrospective SARS-COV-2 infection severe COVID-19 significantly higher Standard deviation Version [DOI] 10.3390/tomography8030100 PMC 바로가기 [Article Type] Observational Study
Influence of socioeconomic status on functional recovery after ARDS caused by SARS-CoV-2: a multicentre, observational studyObservational Study Published on 2022-04-222022-10-05 Journal: BMJ Open [Category] COVID19(2023년), SARS, 임상, [키워드] acute respiratory distress alteration approved ARDS Berlin criteria Care caused Chest CT chest CT scan cohort study Compliance COVID-19 Critical Critical care defined Desaturation develop diagnosed discharge disease eligible Ethics facilitator finding Follow-up form functional Health healthcare High-flow nasal oxygen hospitalised ICU identify impair include Inclusion independent individual influence informed consent form initial Intensive intensive & intensive care International lung multicentre National outcomes oxygen Patient patients with COVID-19 peer-reviewed performed Primary outcome Prognosis protection protocol Pulmonary function tests Quality of life rehabilitation respiratory Respiratory function respiratory infections Respiratory Support risk SARS-COV-2 infection Severe case severity Study protocol syndrome [DOI] 10.1136/bmjopen-2021-057368 PMC 바로가기 [Article Type] Observational Study
Recent advances in passive immunotherapies for COVID-19: The Evidence-Based approaches and clinical trialsReview Published on 2022-04-212022-10-04 Journal: International immunopharmacology [Category] COVID19(2023년), SARS, 변종, 임상, 치료제, [키워드] 2019-nCoV, 2019 novel coronavirus Abstract accompany ACE-2, Angiotensin-Converting Enzyme-2 acute respiratory disease syndrome acute respiratory distress acute respiratory syndrome ADE, Antibody-dependent enhancement adverse effect AE(s), Adverse effect(s) AEs approach ARDS ARDS, acute respiratory distress syndrome CAR, Chimeric antigen receptor Cellular Immunotherapy clinical trial Community complementary Convalescent plasma (CP) therapy coronavirus COVID-19 COVID-19 vaccination COVID-19 vaccines COVID-19, Coronavirus disease 2019 CPT, Convalescent plasma therapy CRP, C-reactive protein CRS, Cytokine release syndrome CT(s), Clinical trial(s) Cytokine storm Efficacy effort emerging disease epidemiological ESR, Erythrocyte sedimentation rate FCR, Fc receptor FDA, Food and Drug Administration global pandemic GM-CSF, granulocyte-macrophage colony-stimulating factor group GVHD, Graft-versus-host disease HBV, Hepatitis B HCV, Hepatitis C highlight HIV, Human immunodeficiency virus HLH, Hemophagocytic lymphohistiocytosis Human I.V., Intravenous IBD, Inflammatory bowel disease IFN, interferon IGG, immunoglobulin g immunomodulation Immunotherapy Inflammation inhibiting International investigated IVIG, intravenous immunoglobulin LAG-3, Lymphocyte-activation gene 3 LDH, lactate dehydrogenase mAb(s), Monoclonal antibody(s) MERS-COV, Middle East respiratory syndrome-corona virus monoclonal antibody MV, Mechanical ventilation Passive Passive immunotherapy PCR, polymerase chain reaction PD-1, Programmed cell death protein-1 platform RA, Rheumatoid arthritis RBD, receptor-binding domain recent reduced SARS-CoV-2 SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2 syndrome TIM-3, T cell immunoglobulin domain and mucin domain-3 TNF, Tumor Necrosis Factor TRALI, Transfusion-related acute lung injury treating COVID-19 patient Treatment Vaccine variants of SARS-CoV-2 VEGF, Vascular endothelial growth factor Viral load viral neutralization [DOI] 10.1016/j.intimp.2022.108786 PMC 바로가기 [Article Type] Review
Targeting of neutrophil activation in the early phase of the disease for prevention of Coronavirus disease‐19 severityReview Published on 2022-04-202023-06-16 Journal: Microbiology and immunology [Category] COVID19(2023년), MERS, SARS, [키워드] ARDS COVID‐19 GPI‐80 infection immunity neutrophil [DOI] 10.1111/1348-0421.12978 PMC 바로가기 [Article Type] Review
Rapidly improving acute respiratory distress syndrome in COVID-19: a multi-centre observational studyObservational Study Published on 2022-04-142022-10-04 Journal: Respiratory Research [Category] 임상, [키워드] acute respiratory distress acute respiratory distress syndrome Acute respiratory failure ARDS association consecutive patient contribute coronavirus coronavirus disease COVID-19 criteria defined determine distress fraction greater Greece high mortality rate ICU increasingly intensive care unit interquartile range intubated patient intubation Invasive mechanical ventilation less median Mortality occurred oxygen pandemic PaO Patient patients with ARDS patients with COVID-19 Pneumonia Prevalence prevalent Prognosis receiving reported severe ARDS syndrome trajectory trials with COVID-19 [DOI] 10.1186/s12931-022-02015-8 PMC 바로가기 [Article Type] Observational Study
A multicenter, open-label, randomized, proof-of-concept phase II clinical trial to assess the efficacy and safety of icatibant in patients infected with SARS-CoV-2 (COVID-19) and admitted to hospital units without invasive mechanical ventilation: study protocol (ICAT-COVID)SARS-CoV-2(COVID-19)에 감염되어 침습적 기계 환기 없이 병원에 입원한 환자에서 이카티반트의 효능과 안전성을 평가하기 위한 다기관, 공개 라벨, 무작위, 개념 증명 II상 임상 시험: 연구 프로토콜(ICAT-COVID)Article Published on 2022-04-122022-09-11 Journal: Trials [Category] COVID19(2023년), SARS, 임상, [키워드] 1:1 ACE2 acute respiratory distress acute respiratory distress syndrome Antigen ARDS attacks bradykinin caused Clinical efficacy clinical status clinical trial ClinicalTrials Comorbidity control group COVID-19 COVID-19 patient COVID-19 patients COVID-19 pneumonia Cytokine storm death Diagnosis discharge discharged doses effective Effectiveness Efficacy Efficacy and safety eligible Endothelial cell endothelial cells EudraCT Evidence evidence of expected experimental group global pandemic Healthcare system Healthcare systems hospital Hospitalized Icatibant include infected with SARS-CoV-2 Inflammatory response inhibiting invasive mechanical Invasive mechanical ventilation Mortality multicenter Open-label outcome Patient patients hospitalized Pneumonia Primary outcomes protease pulmonary infiltrates Radiographic randomization Randomized receive receptor receptor antagonist respiratory distress Respiratory distress syndrome RT-PCR Safe Sample size SARS SARS-CoV-2 secondary Secondary outcomes Spain Standard of care Study protocol subcutaneously Symptoms syndrome the SARS-CoV-2 the WHO thought treat Treatment viral infection with COVID-19 working hypothesis [DOI] 10.1186/s13063-022-06219-7 PMC 바로가기 [Article Type] Article