Utilization of Random Forest Classifier and Artificial Neural Network for Predicting Factors Influencing the Perceived Usability of COVID-19 Contact Tracing “MorChana” in Thailand태국에서 COVID-19 접촉 추적 "MorChana"의 인지된 사용성에 영향을 미치는 요인을 예측하기 위한 랜덤 포레스트 분류기 및 인공 신경망 활용Article Published on 2022-06-292022-09-11 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), SARS, 변종, [키워드] acceptance Accuracy affecting ANN artificial Artificial neural network cause causes Classifier condition Contact Contact tracing convenience sampling COVID-19 COVID-19 pandemic evaluate Factor forest framework Government habit help human behavior Intention machine learning algorithm Machine learning algorithms methodology mitigate motivation Mutation network Neural Perceived protection random Random forest random forest classifier reduce response severity Spread suggested technology theory tracing Usability utilization variants virus [DOI] 10.3390/ijerph19137979 PMC 바로가기 [Article Type] Article
A Game of Infection – Song of Respiratory Viruses and Interferons감염의 게임 - 호흡기 바이러스와 인터페론의 노래Review Published on 2022-06-292022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID19(2023년), SARS, 치료제, [키워드] 2019 coronavirus disease acute respiratory syndrome Antiviral Antiviral strategies antiviral strategy cause caused coronavirus coronavirus – COVID-19 coronavirus disease Coronavirus-2 COVID-19 COVID-19 pandemic CoVs death deaths disease pathogenesis driving effective flu game Health Host Host immune response host immune responses immune responses Infection Influenza influenza A influenza A virus Influenza virus influenza viruses innate immune innate immune response innate immune responses innate immune system Innate immunity mechanism outcome pandemic Pandemics pathogen Pathogenesis Pathogens recorded Research respiratory SARS-CoV-2 Severe acute respiratory syndrome singular Song Spanish flu swine flu therapeutic Topic translated virus virus infection Virus-host interaction Virus-host interactions while writing [DOI] 10.3389/fcimb.2022.937460 PMC 바로가기 [Article Type] Review
The genetic architecture of pneumonia susceptibility implicates mucin biology and a relationship with psychiatric illness Research Published on 2022-06-292022-10-05 Journal: Nature Communications [Category] 신약개발, 유전자 메커니즘, [키워드] Analysis association cause clinically correlation death Diagnosis Evidence Genetic genetic architecture genetics histocompatibility complex region identify implicated mapped Meta-analysis MUC5AC Necrosis overlap pathway phenotype Pneumonia Precision Psychiatric receptor risk risk score smoking Support susceptibility target targets TNFRSF1A Treatment utilised variant widespread [DOI] 10.1038/s41467-022-31473-3 [Article Type] Research
Long COVID burden and risk factors in 10 UK longitudinal studies and electronic health records Research Published on 2022-06-282022-10-05 Journal: Nature Communications [Category] 유전자 메커니즘, [키워드] age Analysis Asthma cause collected Community COVID COVID-19 COVID-19 case diagnostic EHR EHR data Electronic health record electronic healthcare record Factors female Frequency Inconclusive Increasing individual individuals with COVID-19 Long longitudinal study mental health parameters ranged risk factor Sex Symptom Symptoms [DOI] 10.1038/s41467-022-30836-0 [Article Type] Research
Potential Autoimmunity Resulting from Molecular Mimicry between SARS-CoV-2 Spike and Human ProteinsSARS-CoV-2 스파이크와 인간 단백질 간의 분자 모방으로 인한 잠재적 자가면역Article Published on 2022-06-282022-09-11 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] Adverse reactions AlphaFold2 antibody Antibody binding Asymptomatic Autoimmune Autoimmunity calcium cardiac disease cause coronavirus coronavirus SARS-CoV-2 COVID-19 COVID-19 complication COVID-19 complications COVID-19 pathogenesis COVID-19 patients cross-reacting antibodies disease disorder Epitopes example explanation highlight host protein host proteins hotspot Human human proteins implication induce investigated involved machine learning mimicry molecular molecular dynamics molecular mimicry motif omicron outcomes platelet activation Potential PRKG1 Protein protein structure protein structure comparison reduce Regulation resulting SARS-CoV-2 SARS-CoV-2 spike spike Symptom therapeutic intervention therapeutic interventions thrombocytopenia Thrombopoietin tropomyosin Vaccine Vaccine design variant Viral Viral antigen viral antigens [DOI] 10.3390/v14071415 PMC 바로가기 [Article Type] Article
A diminished immune response underlies age-related SARS-CoV-2 pathologies감소된 면역 반응은 연령 관련 SARS-CoV-2 병리의 기초가 됩니다Article Published on 2022-06-282022-09-12 Journal: Cell Reports [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] Adaptive immune response advanced age aging B cell Bcl6 cause Ccr6 characterization Cohort Comorbidity COVID-19 CP: Immunology elevated FOXP3 hamsters host response IL-17 immune response Immunity increase in Ki67 Lungs morbidity Mortality MPO Neutralizing antibodies neutrophil Neutrophils Older pathology phenotype Post-infection reduced respiratory tract resulting SARS-CoV-2 SARS-COV-2 infection significantly Support suppressor T cells. T cell TGF-β These data tissue repair virus [DOI] 10.1016/j.celrep.2022.111002 PMC 바로가기 [Article Type] Article
A one-year follow-up study on dynamic changes of leukocyte subsets and virus-specific antibodies of patients with COVID-19 in Sichuan, China중국 쓰촨성 코로나19 환자의 백혈구 하위 집합 및 바이러스 특이 항체의 동적 변화에 대한 1년 추적 연구Article Published on 2022-06-272022-09-12 Journal: International Journal of Medical Sciences [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] antibodies antibody cause CD4+ CD8+ change changed China circulating conducted discharge discharged Factor fluctuation Follow-up follow-up study gradually increased healthy hospital IgG and IgM IgG antibody IgM immune response inactivated leukocyte Leukocyte subsets Neutrophil-to-lymphocyte ratio NK cell observé participant Patient patients with COVID-19 protective antibodies recovered patient remained SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination subset Vaccine Virus-specific antibody. Virus-specific IgG [DOI] 10.7150/ijms.71286 PMC 바로가기 [Article Type] Article
Immunometabolic analysis shows a distinct cyto-metabotype in Covid-19 compared to sepsis from other causesResearch article Published on 2022-06-242022-10-05 Journal: Heliyon [Category] 바이오마커, 치료기술, [키워드] accompanied Analysis cause CD14+ CD14+ monocyte CD8+ T cells change characteristic Cohort concentrations controls correlated COVID-19 Critical cytokine Cytokine release syndrome Disease progression disease severity expression flow cytometry greater healthy control Hypothesis immune checkpoint immune response immunometabolism involved Lipid mechanism metabolic derangement metabolic risk factor metabolism monocytopenia mononuclear cell multiplex pandemic Pathway analysis Patient PBMC PBMCs PD-L1 Peripheral blood Phosphatidylcholine plasma plasma concentration recruited reduced reflect Result Sepsis serum severe cases severity shown SOFA score Support systemic inflammatory response the disease Treg Tryptophan unique was increased was performed [DOI] 10.1016/j.heliyon.2022.e09733 [Article Type] Research article
COVID-19 outbreak in vaccinated patients from a haemodialysis unit: antibody titres as a marker of protection from infection혈액 투석실에서 예방 접종을 받은 환자의 COVID-19 발생: 감염으로부터 보호하는 지표로서의 항체 역가Article Published on 2022-06-232022-09-11 Journal: Nephrology, dialysis, transplantation : official p [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] 95% CI acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Alpha Alpha variant anti-S anti-S IgG Anti-spike Antibody titre BNT162b2 BNT162b2 mRNA BNT162b2 mRNA vaccination BNT162b2 vaccine Casirivimab cause Clinical data Combination confidence interval coronavirus coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 infection COVID-19 outbreak dialysis dialysis room Haemodialysis humoral Humoral response identify IgG Imdevimab immune correlate immune correlates Immunoglobulin Immunoglobulin G Immunosuppression increased risk Infection interquartile range IQR marker monoclonal antibodies monoclonal antibody mRNA vaccination multivariable analysis neutralization Odds ratio outbreak Patient patients prevented recorded reduced respiratory SARS-CoV-2 SARS-COV-2 infection serological response severe acute respiratory syndrome Coronavirus severe coronavirus disease severe COVID-19 severe disease the patient titre treated uninfected vaccination Vaccines variant were infected with COVID-19 [DOI] 10.1093/ndt/gfac016 PMC 바로가기 [Article Type] Article
The role of direct oral anticoagulants in the era of COVID-19: are antiviral therapy and pharmacogenetics limiting factors?코로나19 시대 직접 경구용 항응고제의 역할: 항바이러스제와 약물유전학이 제약 요인인가?Article Published on 2022-06-222022-09-11 Journal: Croatian Medical Journal [Category] 유전자 메커니즘, 치료제, [키워드] Anticoagulant Anticoagulant treatment Anticoagulants anticoagulation Antiviral agents antiviral therapy cause Coagulation system COVID-19 COVID-19 patient COVID-19 patients diagnosis of COVID-19 DOAC DOACs drug heparin Hospital admission hospitalized patient limit morbidity morbidity and mortality oral anticoagulant Outpatient outpatients Pathogenesis Patient patients with COVID-19 pharmacokinetic required therapy Thromboinflammation Treatment [DOI] 10.3325/cmj.2022.63.287 PMC 바로가기 [Article Type] Article