MERS-CoV – Page 21 – Communicable Diseases Research

Evolutionary Perspective and Theories on the Possible Origin of SARS-CoV-2

Infectious Disease

Published on 2021-10-222022-10-31
Journal: Cureus [Category] COVID-19,

[키워드] acute respiratory syndrome Algorithm Amino acid sequences analyses angiotensin-converting enzyme 2 coronavirus expectation furin-like cleavage site Genes hACE2 Host human Angiotensin-converting enzyme identify interact MERS-CoV meta-analyses Middle East Multiple sequence alignment Next-generation sequencing origin outbreak performed Phylogenetic analysis platform Protein RaTG13 RdRP respiratory syndrome coronavirus RNA-dependent RNA polymerase S1/S2 SARS-CoV SARS-CoV-2 sequence similarity subunit systematic review the SARS-CoV-2 the spike protein theory trajectory transfer vipr whole genome sequence zoonotic zoonotic transfer
[DOI] 10.7759/cureus.18981 PMC 바로가기 [Article Type] Infectious Disease

Middle East respiratory syndrome coronavirus vaccine based on a propagation-defective RNA replicon elicited sterilizing immunity in mice

Article

Published on 2021-10-222023-06-15
Journal: Proceedings of the National Academy of Sciences of [Category] MERS,

[키워드] coronavirus MERS-CoV RNA replicon Vaccine
[DOI] 10.1073/pnas.2111075118 PMC 바로가기

Therapeutic perceptions in antisense RNA-mediated gene regulation for COVID-19

COVID-19에 대한 안티센스 RNA 매개 유전자 조절의 치료적 인식

Article

Published on 2021-10-202022-09-11
Journal: Gene [Category] SARS, 유전자 메커니즘,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Algorithm antisense Antisense RNA base Biotechnology BLAST center Complete coronavirus COVID-19 dataset disease downloaded effective therapy effective vaccine Effective vaccines Gene regulation hybridizing identify input marker mechanism MERS MERS-CoV money normality nucleotide nucleotide sequence nucleotides occur ORF1ab platform Regulation reported Repository Research RNA Safe SARS-CoV SARS-CoV-2 sequence Sequence 2 sequences severe acute respiratory syndrome Coronavirus single-stranded strain therapeutic therapy translation treat vaccination Vaccine Wuhan Wuhan, China
[DOI] 10.1016/j.gene.2021.145839 PMC 바로가기 [Article Type] Article

Visible blue light inhibits infection and replication of SARS-CoV-2 at doses that are well-tolerated by human respiratory tissue

가시광선은 사람의 호흡기 조직이 잘 견딜 수 있는 용량으로 SARS-CoV-2의 감염 및 복제를 억제합니다.

Article

Published on 2021-10-182022-09-10
Journal: Scientific Reports [Category] MERS, SARS, 치료제,

[키워드] antibody antiviral therapeutics approach Betacoronavirus Cell density clinically coronavirus disease Coronavirus disease 2019 COVID-19 demonstrated dependent on dose dose-dependent manner doses effective epithelial epithelial tissues expand High dose inactivated Infection inhibit inhibited Inorganic LEDs Intervention Lasers, LEDs and light sources light-emitting diode mammalian cell MERS MERS-CoV Microbiology mitigate monolayer Optics and photonics Post-infection Replication replication of SARS-CoV-2 respiratory tissue Safe SARS-CoV-1 SARS-CoV-2 SARS-COV-2 infection single-cell therapeutic tissue Vaccine Vero E6 Vero E6 cell VERO E6 cells viability Virology Visible visible light wavelength
[DOI] 10.1038/s41598-021-99917-2 PMC 바로가기 [Article Type] Article

Genetic Insights into the Middle East Respiratory Syndrome Coronavirus Infection among Saudi People

Article

Published on 2021-10-172022-10-28
Journal: Vaccines [Category] COVID-19,

A CRISPR-based and post-amplification coupled SARS-CoV-2 detection with a portable evanescent wave biosensor

CRISPR 기반 및 증폭 후 결합된 SARS-CoV-2 탐지와 휴대용 소멸파 바이오센서

Article

Published on 2021-10-152022-09-11
Journal: Biosensors & bioelectronics [Category] SARS, 치료기술, 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 amplification autonomous biosensor cause Chain Reaction cleavage cleaved coronavirus coronavirus disease Coronavirus disease 2019 coronavirus strains COVID-19 CRISPR CRISPR-Cas13a detect detection Diagnosis diagnosis of COVID-19 downstream enzyme Evanescent evanescent field Evanescent wave fiber followed by hybridization Hybridization chain reaction Infection MERS MERS-CoV optical Optical fiber ORF1 ORF1ab oropharyngeal swabs pandemic platform point-of-care public health reported reporter RNA SARS-CoV SARS-CoV-2 SARS-CoV-2 detection sensitivity sequence severe acute respiratory syndrome Coronavirus Spread
[DOI] 10.1016/j.bios.2021.113418 PMC 바로가기 [Article Type] Article

Infection Control in the Era of COVID-19: A Narrative Review

Review

Published on 2021-10-142022-10-27
Journal: Antibiotics [Category] COVID-19,

Promising Antiviral Activities of Natural Flavonoids against SARS-CoV-2 Targets: Systematic Review

SARS-CoV-2 표적에 대한 천연 플라보노이드의 유망한 항바이러스 활성: 체계적인 검토

Review

Published on 2021-10-142022-09-10
Journal: International Journal of Molecular Sciences [Category] MERS, SARS, 치료법, 치료제,

[키워드] 3CLpro activities activity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration Analysis baicalein baicalin caused Clinical studies clinical study Combination coronavirus COVID-19 pandemic derivatives drug Effect EGCG flavonoid flavonoids focus Immunity in silico in vitro In vitro studies in vitro study in vivo investigated lack less MERS MERS-CoV Mutation myricetin natural nucleocapsid protease public health quercetin respiratory review SARS-CoV SARS-CoV-2 severe acute respiratory syndrome Coronavirus silico studies strain synthetic drugs tannic acid target targets the disease therapeutic intervention therapeutic potential Vaccines viruses
[DOI] 10.3390/ijms222011069 PMC 바로가기 [Article Type] Review

Effect of identified non-synonymous mutations in DPP4 receptor binding residues among highly exposed human population in Morocco to MERS-CoV through computational approach

Research Article

Published on 2021-10-142022-10-28
Journal: PLoS ONE [Category] COVID-19,

The PERK/PKR-eIF2α Pathway Negatively Regulates Porcine Hemagglutinating Encephalomyelitis Virus Replication by Attenuating Global Protein Translation and Facilitating Stress Granule Formation

Cellular Response to Infection

Published on 2021-10-132022-10-30
Journal: Journal of Virology [Category] Coronavirus, MERS,

[키워드] activate activated activating Activation acute respiratory syndrome addition antiviral drugs antiviral role Betacoronavirus cause caused Cell Characteristics coronavirus Coronavirus replication coronavirus-infected cell coronavirus-infected cells Coronaviruses decrease disease Diseases double-stranded eIF2α eIF2α Encephalomyelitis Endoplasmic reticulum endoplasmic reticulum stress ER stress facilitate Facilitating Formation Granule high mortality rate Host Human in vitro in vivo infected cells Infection inhibited innate response Interaction interferon invading pathogen mechanism MERS-CoV Middle East modulate nerve cell neurotropic new treatment strategy Occurrence outcome pathogenic pathway Phosphorylation PKR porcine hemagglutinating encephalomyelitis virus promoted Protein protein translation regulate regulated Replication repressed respiratory syndrome coronavirus reveal SARS-CoV SARS-CoV-2 signaling pathway specific treatment stress granule suppressed target translation attenuation triggered turn unfolded protein response UPR viral proliferation viral replication virus
[DOI] 10.1128/JVI.01695-21 PMC 바로가기 [Article Type] Cellular Response to Infection