Development of a Portable, Ultra-Rapid and Ultra-Sensitive Cell-Based Biosensor for the Direct Detection of the SARS-CoV-2 S1 Spike Protein AntigenLetter Published on 2020-05-312022-10-29 Journal: Sensors (Basel, Switzerland) [Category] COVID-19, MERS, SARS, [키워드] addition antibody Antigen applied Asymptomatic Bioelectric Recognition Assay (BERA) biosensor cellular chimeric coronavirus COVID-19 pandemic cross-reactivity detect detection Detection limit development Direct expressed individuals mammalian cell membrane engineering membrane-bound nucleocapsid protein number of infected pandemic patients platform Point-of-Care (POC) Protein provided Recognition S1 spike protein SARS-CoV-2 selective Serological assay severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) spike Spike protein the SARS-CoV-2 virus [DOI] 10.3390/s20113121 PMC 바로가기 [Article Type] Letter
The Impact of COVID-19 Epidemic Declaration on Psychological Consequences: A Study on Active Weibo UsersArticle Published on 2020-03-192022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, MERS, SARS, [키워드] affected Analysis Anxiety approach assist calculated changes in Cognition cognitive collected data Consequences contribute Corona COVID-19 Depression develop emotion emotional Frequency group Health help Impact knowledge less machine-learning mental health negative emotion outbreak Oxford performed populations Positive emotion Practitioner predictive models psychiatrists Psychological psychological condition psychologists public health emergencies Recognition risk Satisfaction sensitivity significantly stability t-test therapy user word frequency analysis [DOI] 10.3390/ijerph17062032 PMC 바로가기 [Article Type] Article
The nuclear hormone receptor NHR-86 controls anti-pathogen responses in C . elegans핵 호르몬 수용체 NHR-86은 C에서 항병원체 반응을 조절한다. 엘레강스Research Article Published on 2019-01-222022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] activate Activation adaptive Analysis Author bacterial pathogen baseline bind biological function canonical characterized chromatin chromatin immunoprecipitation Control determine Drosophila effector elegan elegans exogenous ligands experiments family function Genetic genetic screen Genome homolog hormone receptor hormone receptors host response Human immune immune activation immunostimulatory induce Infection innate immune activation majority MAPK modulate nuclear pathogen pathway PMK-1 positioned promoter promoters Protective Protein provide Pseudomonas aeruginosa Recognition Regulation required response small molecule target Transcription transcription factor transcription factors transcriptional transcriptional regulator transcriptional response Transcriptome [DOI] 10.1371/journal.pgen.1007935 PMC 바로가기 [Article Type] Research Article
The Nuclear Immune Receptor RPS4 Is Required for RRS1 SLH1 -Dependent Constitutive Defense Activation in Arabidopsis thaliana핵 면역 수용체 RPS4는 Arabidopsis thaliana에서 RRS1 SLH1 -의존적 구성 방어 활성화에 필요합니다Research Article Published on 2014-10-232022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] absence activate Activation Agrobacterium allele Amino acid Analysis Arabidopsis Arabidopsis thaliana Bacterial C-terminal Cell complex conducted Defense disease DNA binding domain dominant downstream effector effectors ENCODE function Genes Genetic genetic screen growth hypotheses identify Immune receptor immune receptors immune responses Immunity inactive insertion leucine loss-of-function mutation loss-of-function mutations mammalian mechanism motif mutant mutants Mutation NLR NLRs nuclear nucleotide overlap pathogen performed plant plants Protein Pseudomona Pseudomonas R genes receptor Recognition recognize required rescued responses RRS1 secretion Signaling significantly temperature transcribed transcriptional transcriptional activation transcriptional change Trigger triggers type III wild type [DOI] 10.1371/journal.pgen.1004655 PMC 바로가기 [Article Type] Research Article
Defining NELF-E RNA Binding in HIV-1 and Promoter-Proximal Pause RegionsHIV-1 및 프로모터-근위 일시 중지 영역에서 NELF-E RNA 결합 정의Research Article Published on 2014-01-162022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] a major addition analyzed association Author binding binding activity binding domain Biochemistry cellular claimed compared complex Consensus conserved contribute downstream Drosophila elongation elongation factor eukaryotic facilitate Factor functional Gene Genes Genome high affinity HIV-1 identify in addition to in vitro Interaction modulate molecular negative nuclear nucleotide nucleotides observé pause POLL promoter Protein protein coding gene protein coding genes Protein subunit Quantitative Recognition Region regulate regulated Regulatory required responsible RNA RNA Polymerase II RNA sequence RNA sequences sequence significant increase subunit Support targets thought transcribed Transcription transcription factor transcription factors transcription start site widespread [DOI] 10.1371/journal.pgen.1004090 PMC 바로가기 [Article Type] Research Article
The Principal Genetic Determinants for Nasopharyngeal Carcinoma in China Involve the HLA Class I Antigen Recognition GrooveHLA 클래스 I 항원 인식 그루브와 관련된 중국 비인두암의 주요 유전적 결정인자Research Article Published on 2012-11-292022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] allele allele frequencies alleles Amino acid Analysis analyzed antigens association associations Author binding Cancer carcinoma carried China Chinese chromosome chromosome 6 class Cohort concert dependent on detect detected determinant disease driven by EBV epithelial Epstein-Barr virus examined facilitated GABBR1 Gene gene region genetic influence Genome-wide association study Groove Guangdong Guangxi GWAS HCG9 help High-resolution HLA HLA alleles HLA class I HLA class I gene HLA region HLA-A HLA-A and -B HLA-B HLA-F incidence independent Infection influences influences on Interaction involved large cohort Linkage disequilibrium malignancy molecular motif multivariate Nasopharyngeal carcinoma NPC nucleotide operative OR2H1 over peptide performed physically principal Recognition recognize Region regression analysis replicate Replication resolved risk second sequence SNP SNPs statistical study participant the major histocompatibility the strongest variant variants virus infection [DOI] 10.1371/journal.pgen.1003103 PMC 바로가기 [Article Type] Research Article
Late Recognition of SARS in Nosocomial Outbreak, TorontoDispatch Published on 2005-02-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, [키워드] absence acute respiratory syndrome Clusters Contact dispatch Hospitalization Hospitalized hospitalized patient nosocomial Nosocomial infections outbreak postoperative Recognition recognize SARS Surveillance symptom onset Toronto underlying condition variety [DOI] 10.3201/eid1102.040607 PMC 바로가기 [Article Type] Dispatch