Cellular mechanisms underlying neurological/neuropsychiatric manifestations of COVID-19COVID-19의 신경학적/신경정신과적 징후의 기저에 있는 세포 메커니즘Review Published on 2021-04-012022-09-12 Journal: Journal of medical virology [Category] Fulltext, MERS, 진단, [키워드] acute respiratory syndrome astrocytes Brain brain organoids Cell cells cellular mechanism clinical observation Clinical practice clinically Coronavirus-2 COVID-19 disease disorder effective strategy epithelial cells Evidence Future hematogenous indicate Infection iPS cells manifestation mechanism Mortality neural cells neuroinvasion Neuroinvasive Neurological symptom NEUROLOGY neurons Neuropsychiatric neuropsychiatry neurovirulence. pluripotent stem cells Research respiratory symptoms robust SARS-CoV-2 SARS-COV-2 infection severity specimens the disease Treatment understanding virus [DOI] 10.1002/jmv.26720 PMC 바로가기 [Article Type] Review
Development and performance evaluation of the first in-house multiplex rRT-PCR assay in Bangladesh for highly sensitive detection of SARS-CoV-2Article Published on 2021-04-012022-10-04 Journal: Journal of virological methods [Category] MERS, SARS, 진단, 치료기술, 치료법, 치료제, [키워드] Accuracy acute respiratory syndrome approaches assays checked clinical Clinical management Concentration Coronavirus-2 Cost effective assay country COVID-19 cross-reactivity detect develop developing country development diagnostic Efficiency Equal equipment expand Final Health In-house kit Infection prevention Initially Internal control Laboratory lack multiplex Multiplex assay Multiplex rRT-PCR Nasopharyngeal swab Nucleocapsid gene objective pandemic Perspective primer probe reproducibility Result reverse-transcriptase PCR RNase P rRT-PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA sensitivity Sensitivity and specificity Singleplex rRT-PCR specificity specimens target gene was done [DOI] 10.1016/j.jviromet.2021.114147 PMC 바로가기 [Article Type] Article
Diagnosis of SARS-CoV-2 Infection with LamPORE, a High-Throughput Platform Combining Loop-Mediated Isothermal Amplification and Nanopore Sequencing루프 매개 등온 증폭과 나노포어 시퀀싱을 결합한 고처리량 플랫폼인 LamPORE를 사용한 SARS-CoV-2 감염 진단Virology Published on 2021-03-292022-09-10 Journal: Journal of Clinical Microbiology [Category] SARS, 치료기술, [키워드] 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 approach clinical samples collected coronavirus Diagnosis diagnosis of SARS-CoV-2 diagnostic diagnostic sensitivity diagnostic specificity evaluated extracted RNA Genome Infection isothermal amplification LamPORE limit limit of detection Loop-mediated isothermal amplification Nanopore nanopore sequencing nose and throat offer Pathogens Patient per day platform produced reduction reproducibility respiratory respiratory pathogen respiratory sample reverse transcriptase reverse transcriptase PCR RNA RT-PCR SARS-CoV-2 SARS-COV-2 infection sensitivity Sequencing severe acute respiratory syndrome Coronavirus specificity specimen specimens Swab symptomatic infection symptomatic patient Symptomatic patients throat swabs UK hospitals [DOI] 10.1128/JCM.03271-20 PMC 바로가기 [Article Type] Virology
Assessment of Sample Pooling for Clinical SARS-CoV-2 Testing임상 SARS-CoV-2 테스트를 위한 샘플 풀링 평가Article Published on 2021-03-192022-09-11 Journal: Journal of Clinical Microbiology [Category] SARS, 치료기술, [키워드] approach assessment automated benefit clinical clinical setting clinical settings coronavirus disease Coronavirus disease 2019 COVID-19 data management detection rate detection system enhanced throughput evaluated frequencies Frequency implementation increases in Laboratory laboratory capacity Occurrence pandemic peaking pooling positive positive sample proportion reduced Reporting Sample SARS-CoV-2 sensitivity significant component specimen specimens suggested Testing threshold transfer Viral load weakly positive [DOI] 10.1128/JCM.01261-20 PMC 바로가기 [Article Type] Article
Characteristics of Viral Shedding Time in SARS-CoV-2 Infections: A Systematic Review and Meta-AnalysisPublic Health Published on 2021-03-192022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, SARS, [키워드] 95% CI Adults asymptomatic infection bioRxiv calculated children chronic disease Chronic diseases Clinical characteristics CNKI corticosteroid treatment COVID-19 determine estimate heterogeneous inclusion criteria log-transformed medRxiv Meta-analysis participant performed Person receiving reported respiratory tract specimen review SARS- CoV-2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections searched shedding significantly specimen specimens Stool stratified subgroup analysis symptomatic infection symptomatic infections systematic review time Transmission Treatment viral shedding viral shedding time VST Web of Science [DOI] 10.3389/fpubh.2021.652842 PMC 바로가기 [Article Type] Public Health
Correlation of SARS-CoV-2 Nucleocapsid Antigen and RNA Concentrations in Nasopharyngeal Samples from Children and Adults Using an Ultrasensitive and Quantitative Antigen Assay초민감성 및 정량적 항원 분석을 사용하여 어린이 및 성인의 비인두 샘플에서 SARS-CoV-2 뉴클레오캡시드 항원 및 RNA 농도의 상관관계Article Published on 2021-03-192022-09-11 Journal: Journal of Clinical Microbiology [Category] SARS, 치료기술, 치료법, [키워드] 95% confidence interval Antigen approach children clinical samples collected Concentration correlated correlation COVID-19 Cutoff cycle threshold diagnosis of COVID-19 diagnostic distribution electrochemiluminescence immunoassay less limit of detection magnitude media MSD nasopharyngeal nucleocapsid nucleocapsid antigens nucleoprotein offer PCR PCR-negative PCR-positive pediatric Quantitative ranged Rapid diagnostic test RDT RDTs RNA RNA concentration RNA concentrations Sample SARS-CoV-2 SARS-CoV-2 N SARS-CoV-2 nucleocapsid sensitivities sensitivity Specificities specificity specimens tested utility was used [DOI] 10.1128/JCM.03077-20 PMC 바로가기 [Article Type] Article
Characterizing the Qatar advanced-phase SARS-CoV-2 epidemicArticle Published on 2021-03-182022-10-29 Journal: Scientific Reports [Category] COVID-19, SARS, [키워드] 95% CI acute respiratory syndrome ad-hoc Asymptomatic Blood Community coronavirus Critical cumulative rate database declining Epidemic Epidemiology Fatality rate Immunity individual individuals Infection National participant PCR PCR positive PCR positivity positive Prevalence Research question SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 epidemic SARS-COV-2 infection serology testing severity Severity rate Source specimens Swab tested viral infection WHO World Health Organization [DOI] 10.1038/s41598-021-85428-7 PMC 바로가기 [Article Type] Article
Risk of mortality in patients infected with SARS-CoV-2 variant of concern 202012/1: matched cohort study우려되는 SARS-CoV-2 변이체에 감염된 환자의 사망 위험 202012/1: 일치 코호트 연구Research Published on 2021-03-102022-09-10 Journal: The BMJ [Category] Fulltext, SARS, 변종, 진단, 치료기술, [키워드] 95% confidence interval age argument circulating SARS-CoV-2 variants circulating variant circulating variants cohort study Community death Deprivation detectability Ethnicity first positive hazard ratio impacted increase in increased mortality index infected with SARS-CoV-2 Infection International Local low risk group Matched measure Mortality National objective outcome measure participant Patient pillar populations positive Probability reduce Result risk SARS-CoV-2 SARS-CoV-2 test SARS-CoV-2 variants setting Sex specimens Spike protein TaqPath test result tested the spike protein variant variant of SARS-CoV-2 VOC-202012/01 with infection [DOI] 10.1136/bmj.n579 PMC 바로가기 [Article Type] Research
Combined SARS-CoV-2 nucleic acid amplification testing and respiratory virus panel RT-PCR on the Hologic Panther Fusion systemArticle Published on 2021-03-102022-10-04 Journal: Journal of Clinical Virology [Category] SARS, 진단, 치료기술, [키워드] 95 % CI amplification carried Clinical diagnosis clinical sensitivity Cohen’s kappa coefficient Combined demonstrated diagnostic evaluate flexible fusion infection control Laboratory testing Mediated moderate nasopharyngeal objective other respiratory virus overlap pandemic Panel Panther Fusion positive provide respiratory respiratory pathogen respiratory virus respiratory viruses Result RT-PCR SARS-CoV-2 SARS-CoV-2 nucleic acid Significant specimen specimens Symptom virus [DOI] 10.1016/j.jcv.2021.104792 PMC 바로가기 [Article Type] Article
Comparison of Serologic Response of Hospitalized COVID-19 Patients Using 8 Immunoassays8개의 면역분석법을 사용한 입원한 코로나19 환자의 혈청학적 반응 비교Comparative Study Published on 2021-03-082022-09-11 Journal: Journal of Korean medical science [Category] SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus antibodies antibody assays caution chemiluminescent immunoassay clinical laboratory collected commercial immunoassay coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 detect discrepant result discrepant results eight ELISA enzyme-linked immunosorbent enzyme-linked immunosorbent assay except for immunoassay immunoassays immunochromatographic Infection IVD Korea Korean Laboratory lateral flow Patient patients positive result respiratory response SARS-CoV-2 serologic serological assessment serum sample serum samples specimens tested [DOI] 10.3346/jkms.2021.36.e64 PMC 바로가기 [Article Type] Comparative Study