Reliability and Repeatability Analysis of Indices to Measure Gait Deterioration in MS Patients during Prolonged Walking장기간 보행 중 다발성 경화증 환자의 보행 악화를 측정하기 위한 지표의 신뢰성 및 반복성 분석Article Published on 2020-09-062022-08-13 Journal: Sensors (Basel, Switzerland) [Category] 임상, [키워드] (range of motion) 6-min walking test analyzed asymmetry caused changes in clinical disability coefficient Coefficient of variation consequence correlated CoV Deterioration disability Effects evaluated Evolution Expanded Disability Status Scale fatigue FIVE Gait Gait deterioration Gait variability Good healthy subjects involved leads lower limb maximum measure motion multiple sclerosis nine outcome Patient Prolonged protocol Quantitative range of motion reliability repeatability ROM scale severity Standard deviation status subgroup subgroups suggested symmetry index synthetic indices Variability Variation walking were assessed were used [DOI] 10.3390/s20185063 PMC 바로가기 [Article Type] Article
African League Against Rheumatism (AFLAR) preliminary recommendations on the management of rheumatic diseases during the COVID-19 pandemicOriginal Article Published on 2020-09-022022-10-31 Journal: Clinical Rheumatology [Category] COVID-19, SARS, [키워드] African African rheumatology Against breast milk Clinical practice conducted COVID-19 COVID-19 pandemic criteria develop disease disease-modifying anti-rheumatic drug DMARD Evidence Infection initial management moderate Musculoskeletal objective Patient Point positive processed Prophylaxis question recommendation recommendations reduced Region representing Result Rheumatic and musculoskeletal diseases rheumatic disease rheumatism rheumatologist rheumatology SARS-CoV-2 Spread stratified subgroup subgroups transmitted Treatment [DOI] 10.1007/s10067-020-05355-2 PMC 바로가기 [Article Type] Original Article
ANDC: an early warning score to predict mortality risk for patients with Coronavirus Disease 2019Research Published on 2020-08-312022-10-30 Journal: Journal of Translational Medicine [Category] COVID-19, MERS, [키워드] Admission analyzed AUC C-reactive protein center Clinical outcome COVID-19 COVID-19 patient COVID-19 patients cut-off value d -dimer death demographic characteristics demonstrated develop District Early warning score enrolled exhibited help high mortality high risk Laboratory less management moderate Mortality mortality risk Neutrophil-to-lymphocyte ratio nomogram Patient patients with COVID-19 physician predict predictor Probability prognostic Quantitative Respiratory failure Result retrospective risk risk factor SARS-CoV-2 Science Stratification subgroups technology Tumor Union Hospital university validation cohort Wuhan, China [DOI] 10.1186/s12967-020-02505-7 PMC 바로가기 [Article Type] Research
Corticosteroid therapy for critically ill patients with COVID-19: A structured summary of a study protocol for a prospective meta-analysis of randomized trialsLetter Published on 2020-08-242022-10-29 Journal: Trials [Category] Coronavirus, MERS, [키워드] administration Analysis ARMS asked assessment Characteristics Chinese clinical trial Comparator group comparison Corticosteroid COVID-19 Critically ill patient defined Dexamethasone disease severity dissemination dose Effect element eligible EudraCT Evidence greater group heterogeneity High dose Hydrocortisone information Interaction Intervention intervention effect intervention group investigator ISRCTN less low dose meta-analyses Meta-analysis meta-regression Methylprednisolone Mortality Network meta-analysis objective Odds ratio Open-label outcome p-values participant Patient per day Placebo placebo-controlled primary analysis Prospective protocol provided quantified random-effect randomised controlled trial randomization Randomized Randomized controlled trials randomized trial Research Risk of bias RoB 2 secondary Serious Adverse Events Standard of care steroid Study protocol subgroup subgroups systematic review the WHO therapeutic dose therapy Treatment Trial trials usual care website WHO [DOI] 10.1186/s13063-020-04641-3 PMC 바로가기 [Article Type] Letter
Comparison of International Classification of Diseases and Related Health Problems, Tenth Revision Codes With Electronic Medical Records Among Patients With Symptoms of Coronavirus Disease 2019Research Published on 2020-08-142022-10-29 Journal: JAMA Network Open [Category] COVID-19, MERS, [키워드] 95% CI 95% CIs Accuracy acute respiratory syndrome Affect age Analysis Bootstrapping calculated classification code cohort study cohorts coronavirus coronavirus disease cough COVD-19 COVID-19 COVID-19 test COVID-19–related symptom downstream downstream analyses Dyspnea female Fever finding generate Hispanic ICD-10 implication Importance inaccuracy Inpatient inpatient status lack Latino measure Negative predictive value NPV objective Outpatient participant Patient patients Pearson performance Point Positive predictive value PPV presenting symptom Prevalence Quantitative Record Relevance Result revision sensitivity setting Sex specificity stratified subgroups Surveillance Symptom Symptoms tested the mean university Utah was performed was used were used white with COVID-19 [DOI] 10.1001/jamanetworkopen.2020.17703 PMC 바로가기 [Article Type] Research
The Critical Need for a Population Health Approach: Addressing the Nation’s Behavioral Health During the COVID-19 Pandemic and BeyondCommentary Published on 2020-08-062022-10-29 Journal: Preventing Chronic Disease [Category] Coronavirus, MERS, [키워드] approach COVID-19 global pandemic Health help highlight identify IMPROVE Intervention Population promote Psychological well-being subgroups total population [DOI] 10.5888/pcd17.200261 PMC 바로가기 [Article Type] Commentary
Preliminary Experience With Low Molecular Weight Heparin Strategy in COVID-19 PatientsPharmacology Published on 2020-08-062022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] 95% CI administration Admission all-cause mortality analyzed anticoagulation association clinical collected Consensus COVID- 19 COVID-19 COVID-19 patient demographic characteristics disease dosage DVT DVT prophylaxis Efficacy Evidence experience group heparin hospitalized COVID-19 patients hospitalized patients hypertension In-hospital in-hospital mortality incidence intermediate Laboratory Laboratory testing laboratory-confirmed LMWH LMWH (low molecular weight heparin) low molecular weight Mortality Older age pathophysiological Patient patients Prevalence Prophylactic Prophylaxis regimen remained Result significant difference significantly Strategy subgroups therapy thrombosis treated Treatment variable weight [DOI] 10.3389/fphar.2020.01124 PMC 바로가기 [Article Type] Pharmacology
Development and Validation of a Deep Learning-Based Model Using Computed Tomography Imaging for Predicting Disease Severity of Coronavirus Disease 2019Bioengineering and Biotechnology Published on 2020-07-312022-10-31 Journal: Frontiers in Bioengineering and Biotechnology [Category] COVID-19, [키워드] 105 patient 95% confidence interval Accuracy Admission assigned AUC characteristic Clinical treatment collected Computed tomography Confusion Coronavirus disease 2019 COVID-19 COVID-19 patient deep deep learning develop development Disease progression disease severity evaluated fatality globe help hospital imaging Infection Intervention material Model Multiple instance learning objective Patient predict prevent disease progression reduce mortality Result risk severe disease severely ill patient subgroup analysis subgroups Symptom test dataset training data university validation with COVID-19 [DOI] 10.3389/fbioe.2020.00898 PMC 바로가기 [Article Type] Bioengineering and Biotechnology
SARS-CoV-2 induced thrombocytopenia as an important biomarker significantly correlated with abnormal coagulation function, increased intravascular blood clot risk and mortality in COVID-19 patientsResearch Published on 2020-07-172022-10-31 Journal: Experimental Hematology & Oncology [Category] COVID-19, [키워드] abnormal coagulation Admission alanine aminotransferase ALT analyzed Aspartate aminotransferase AST biochemical Biomarker Blood blood platelet cardiovascular event cascade Clinical prognosis Coagulation coagulation function Coronavirus disease 2019 coronavirus nucleic acid correlated COVID-19 COVID-19 patient COVID-19 patients death death case diagnosed diagnostic DIC disease disease severity enrolled function Hospitalization Huoshenshan Hospital IgM/IgG increased mortality increased risk INR International intravascular coagulation laboratory parameter lack Liver function Mortality non-severe group normalized occurred Other parameter Patient patients with COVID-19 Platelet positive predict Prothrombin time recovered patients Result risk SARS-CoV-2 severe disease severe group significantly subgroups survival tested thrombin thrombocytopenia Thromboembolism two groups used to evaluate viral disease while Wuhan [DOI] 10.1186/s40164-020-00172-4 PMC 바로가기 [Article Type] Research
Evolution of Salmonella enterica serotype Typhimurium driven by anthropogenic selection and niche adaptation살모넬라 엔테리카 혈청형 Typhimurium의 인위적 선택과 틈새 적응에 의한 진화Research Article Published on 2020-06-082022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, 살모넬라증, [키워드] a minor accumulation acquisition acting adaptation Affect affecting anthropogenic antimicrobial resistance Biology Characteristics characterized circulation clade clone coding sequence coding sequences composed convergent evolution disease disease potential distribution Diversity driven by drug resistance elements elevated Epidemics Epidemiology Evolution exhibit exhibited food safety framework function functional functions Gain gastroenteritis Genes Genetic genomes genotypic genotypic variation group Health Host host adaptation host range host-pathogen interactions human infection IMPROVE Infection information invasive isolate isolates Laboratory less Lineage livestock minor monophasic observation organism outcome pandemic pathogen pathogenicity Population predicted predisposition prophage provide Recombination reflected risk Salmonella Salmonella Typhimurium sequence Sequencing serotype serotypes strain Strains subclade subclades subgroup subgroups survival undergo Variation whole genome Whole genome sequencing [DOI] 10.1371/journal.pgen.1008850 PMC 바로가기 [Article Type] Research Article