Four Weeks Treatment with Glecaprevir/Pibrentasvir + Ribavirin-A Randomized Controlled Clinical Trial글레카프레비르/피브렌타스비르 + 리바비린-A 무작위 대조 임상 시험으로 4주간 치료Randomized Controlled Trial Published on 2022-03-162022-09-11 Journal: Viruses [Category] 임상, 치료제, [키워드] analyzed baseline chronic hepatitis chronic hepatitis C clinical Controlled Controlled trial Course COVID-19 pandemic cure DAA eight Enhancing fibrosis Genotype glecaprevir HCV Health Organization Hepatitis hepatitis C intention to treat Liver fibrosis multicenter naïve open label Patient patients treated pibrentasvir predictor predictors Randomized Randomized controlled trial reducing ribavirin stratified sustained Treatment Trial Viral load virological response Week World Health Organization [DOI] 10.3390/v14030614 PMC 바로가기 [Article Type] Randomized Controlled Trial
Assessment of quality of alcohol-based hand sanitizers used in Johannesburg area during the CoViD‐19 pandemicArticle Published on 2022-03-102022-10-04 Journal: Scientific Reports [Category] MERS, 치료기술, [키워드] 1-propanol absence Acetate Agilent alcohol alcohols analyzed assessment auto Biochemistry can be used Chemistry collected Combination Concentration consumer Coronaviruses ethyl hand sanitizer Health care identify less media methanol outbreak pandemic potentially toxic Prevent propanol Randomly South Africa substandard Transmission World Health Organization [DOI] 10.1038/s41598-022-08117-z PMC 바로가기 [Article Type] Article
Clinical severity of, and effectiveness of mRNA vaccines against, covid-19 from omicron, delta, and alpha SARS-CoV-2 variants in the United States: prospective observational study미국의 오미크론, 델타 및 알파 SARS-CoV-2 변이체의 covid-19에 대한 mRNA 백신의 임상 중증도 및 효과: 전향적 관찰 연구Observational Study Published on 2022-03-092022-09-11 Journal: The BMJ [Category] SARS, 변종, 임상, [키워드] 95% confidence interval adjusted Alpha Alpha variant calculated case-control study circulating clinical Clinical severity controls delta variant disease severity dose effective Effectiveness group Health Organization hospital Hospital admission Hospital admissions Hospital mortality in-hospital mortality less Lineage morbidity and mortality Mortality mRNA vaccine mRNA vaccines Odds ratio omicron Omicron variant Omicron variants outcome Patient patients predominant Prevent progression prospective observational study provided required SARS-CoV-2 variant Sequencing severe disease severity significantly lower test negative The United States the WHO United States vaccine dose variant variants WHO Clinical Progression Scale whole genome Whole genome sequencing World Health Organization [DOI] 10.1136/bmj-2021-069761 PMC 바로가기 [Article Type] Observational Study
Emotion diffusion effect: Negative sentiment COVID-19 tweets of public organizations attract more responses from followersResearch Article Published on 2022-03-082022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] analyses Analysis associational causal relationship contribute Coronavirus disease 2019 country COVID-19 develop diffusion emotion generate health system media Multiple negative negative and positive nine no significant difference organization pandemic positive Probability Research response responses significantly more Topic Treatment triggered variable Weighting World Health Organization [DOI] 10.1371/journal.pone.0264794 PMC 바로가기 [Article Type] Research Article
Intelligent system based comparative analysis study of SARS-CoV-2 spike protein and antigenic proteins in different types of vaccinesResearch Published on 2022-03-072022-10-28 Journal: Beni-Suef University Journal of Basic and Applied Sciences [Category] COVID-19, [키워드] Amino acid Analysis And PCV10 antigenic protein caused China coding Combination comparison coronavirus coronavirus 2 Coronavirus disease 2019 correlation country COVID-19 COVID-19 virus death deaths disease explain Genome Genome signature Genomic coding techniques hepatitis B HIB humans immune response implicated in silico infect intestinal investigated less measles membrane fusion MMR Novel coronavirus pandemic Poliovirus PROTECT protective effect Protein receptor respiratory respiratory infections Result RNA virus rubella S gene S protein SARS-CoV-2 SARS-CoV-2 spike protein sequence severity spike Spread symptomatic case the Coronaviridae the SARS-CoV-2 genome Vaccine Vaccines Variation WHO World Health Organization [DOI] 10.1186/s43088-022-00216-0 PMC 바로가기 [Article Type] Research
Global COVID-19 Vaccine Inequity: Failures in the First Year of Distribution and Potential Solutions for the Future글로벌 코로나19 백신 불평등: 유통 첫 해의 실패와 미래를 위한 잠재적 솔루션Article Published on 2022-03-072022-09-11 Journal: Frontiers in Public Health [Category] SARS, 변종, [키워드] Affect approach benefit country COVAX COVID-19 COVID-19 vaccine COVID-19 vaccines D develop distribution effective European country facilitate failure Future global pandemic Health Organization herd immunity Host Immunity include inequality intellectual property interface International international cooperation Investment knowledge majority manufacturing—R& not effective pandemic Pharmaceutical Company pharmaceutical industry Potential pricing resulting risk SARS-CoV-2 pandemic solution Support Technology transfer the SARS-CoV-2 transfer vaccination rate vaccination rates Vaccine Vaccines variant World Health Organization Year [DOI] 10.3389/fpubh.2022.821117 PMC 바로가기 [Article Type] Article
SARS-CoV-2 origin, myths and diagnostic technology developmentsReview Published on 2022-03-042022-11-01 Journal: The Egyptian Journal of Medical Human Genetics [Category] COVID-19, [키워드] accelerated approach assays baseline Body caused China COVID-19 CRISPR Culture Diagnosis diagnostic Diagnostic method diagnostics drug resistance Effect ELISA epidemiological evaluated Factor False negative Future Genome Healthcare systems implication information Intervention isothermal amplification knowledge Laboratory LAMP less management morbidity myth pandemic paucity of data profile provided reducing repeated reported RT-PCR SARS-CoV-2 SARS-CoV-2 virus sensitivity specificity targeted therapy the patient TMA Treatment virus virus genome WHO World Health Organization Zika virus [DOI] 10.1186/s43042-022-00255-3 PMC 바로가기 [Article Type] Review
Effectiveness of tocilizumab in the treatment of hospitalized adults COVID-19: A systematic review and meta-analysis입원한 성인 COVID-19 치료에서 토실리주맙의 효과: 체계적인 검토 및 메타 분석Meta-Analysis Published on 2022-03-042022-09-11 Journal: Medicine [Category] SARS, 임상, 진단, [키워드] 30-Day mortality 95% CI 95% confidence interval Admission Analysis assigned clinical control groups Controlled controlled trials coronavirus coronavirus disease COVID-19 COVID-19 patients death determine discharge Effectiveness hazard ratio Health Health Organization Hospitalized hospitalized COVID-19 patients incidence Infection intensive care intensive care unit admission mechanical ventilation Meta-analysis meta-analysis model Mortality optimal dose outcome Patient performed random-effect Randomized controlled trial Randomized controlled trials Randomly receive reduced registry Relative risk required review risk searched Serious Adverse Event Serious Adverse Events significantly Spread systematic review Tocilizumab Treatment usual care usual care alone was used with COVID-19 World Health Organization [DOI] 10.1097/MD.0000000000028967 PMC 바로가기 [Article Type] Meta-Analysis
Current challenges in different approaches to control COVID-19: a comprehensive reviewReview Published on 2022-03-032022-10-28 Journal: Bulletin of the National Research Centre [Category] COVID-19, [키워드] airborne antiviral therapy approach Asymptomatic asymptomatic patient caused clinical trial Community Complete compounds Contagion coronavirus country COVID-19 COVID-19 infection current drug library globe growth health emergency highlight information International lockdown measure Novel coronavirus outbreak pandemic pandemic disease pathway Patient required Research respiratory respiratory tract infection Risk factors SARS-CoV-2 SARS-CoV-2 virus Spread therapy Transmission treat Treatment treatment of COVID-19 treatment strategy vaccination variant virus World Health Organization [DOI] 10.1186/s42269-022-00730-2 PMC 바로가기 [Article Type] Review
Myocarditis and pericarditis in adolescents after first and second doses of mRNA COVID-19 vaccinesObservational Study Published on 2022-03-022022-10-05 Journal: European heart journal. Quality of care & clinical [Category] SARS, 임상, [키워드] 95% CI 95% confidence interval age calculated database demonstrated determine dose first dose increase increased risk mRNA COVID-19 vaccine mRNA COVID-19 vaccines myocarditis Myocarditis • Pericarditis • Tozinameran • Elasomeran • Pharmacovigilance • mRNA COVID-19 vaccines. no difference Odds ratio performed Pericarditis pharmacovigilance raised recorded Registered Reporting risk second dose Sex significant difference vaccination Vaccine while World Health Organization [DOI] 10.1093/ehjqcco/qcab090 PMC 바로가기 [Article Type] Observational Study