1 H, 13 C and 15 N chemical shift assignment of the stem-loop 5a from the 5′-UTR of SARS-CoV-2Article Published on 2021-01-232022-10-27 Journal: Biomolecular Nmr Assignments [Category] Coronavirus, COVID-19, SARS, [키워드] 5′-UTR 5′-untranslated region 5′-UTR Affect antiviral drug asymmetric conserved COVID-19 pandemic COVID19-NMR element feature Genome Major NMR spectroscopy nucleotide positive Replication RNA RNA genome SARS-CoV-2 sequence single-stranded SL5a Solution NMR spectroscopy supplementary material targets translation viral replication virus [DOI] 10.1007/s12104-021-10007-w PMC 바로가기 [Article Type] Article
Perceived barriers to the practice of preventive measures for COVID-19 pandemic among health professionals in public health facilities of the Gamo zone, southern Ethiopia: a phenomenological studyResearch Article Published on 2021-01-222022-10-28 Journal: BMC Public Health [Category] COVID-19, MERS, [키워드] activities activity Affect affecting Analysis And Ethiopia approach barriers Care caused consequence coronavirus COVID-19 COVID-19 pandemic global pandemic Health Health care worker hygiene IMPROVE individuals influences lack novel pandemic participant Perceived Personal protective equipment Phenomenological study preventive measure preventive measures Pro professional professionals public health Purposive sampling recognize recruited Research Result Seven Stress supplementary material Support was used zone [DOI] 10.1186/s12889-021-10256-3 PMC 바로가기 [Article Type] Research Article
Feasibility of using alternative swabs and storage solutions for paired SARS-CoV-2 detection and microbiome analysis in the hospital environmentResearch Published on 2021-01-222022-10-29 Journal: Microbiome [Category] COVID-19, [키워드] 16S rRNA gene Abstract analyses Analysis Antibiotics collected COVID COVID-19 COVID-19 testing demonstrated detect Determining diagnostic driven by evaluated experiment FIVE global health Government hospital ICU impacted in viral include indicated infections initiative intensive care Laboratory lack limit of detection microbial community Microbiome nasal Particles Patient patients performed public health Result RNA RNase RNases RT-qPCR SARS-CoV-2 SARS-CoV-2 detection Sequencing supplementary material Swab swabs tested the patient transmission of SARS-CoV-2 Transport media transported Viral particles virus VTM was measured [DOI] 10.1186/s40168-020-00960-4 PMC 바로가기 [Article Type] Research
Short-term cardiac outcome in survivors of COVID-19: a systematic study after hospital dischargeCOVID-19 생존자의 단기 심장 예후: 퇴원 후 체계적인 연구Observational Study Published on 2021-01-222022-09-11 Journal: Clinical Research in Cardiology [Category] 임상, 치료기술, [키워드] 105 patient 105 patients Abnormalities abnormality Abstract cardiac caused collected controls COVID-19 COVID-19 patient COVID-19 patients cross-sectional cross-sectional study Diastolic function ECG echocardiography examined Follow-up follow-up visits functional greater heart hospital discharge Hospitalized Infection limitation lung Lung ultrasound matched controls median Mild-to-moderate morbidity and mortality no significant differences objective outcome Patient patients patients who survived pulmonary involvement recruited reported Result severity severity of illness significant difference significantly supplementary material survivor Systolic function Tissue-Doppler imaging ventricular with COVID-19 [DOI] 10.1007/s00392-020-01800-z PMC 바로가기 [Article Type] Observational Study
Using Baidu search values to monitor and predict the confirmed cases of COVID-19 in China: – evidence from Baidu indexResearch Article Published on 2021-01-212022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, MERS, [키워드] Analysis analyzed association average Baidu Baidu index caused center China collected confirmed case confirmed cases coronavirus disease correlated cough COVID-19 COVID-19-related symptom Daily distribution Engineering Epidemics Evidence fatigue Fever global pandemic growth index Internet searching Johns Hopkins University measure MONITOR New outbreak pandemic positive correlation predict Prevent Region Regional Research Result retrieved robust Science Shortness of breath significantly Spearman’s correlation sputum sputum production supplementary material Symptom symptoms of COVID-19 System time lag viruses was used Web-based data [DOI] 10.1186/s12879-020-05740-x PMC 바로가기 [Article Type] Research Article
Evaluation and improvement of the National Early Warning Score (NEWS2) for COVID-19: a multi-hospital studyCOVID-19에 대한 국가 조기 경보 점수(NEWS2) 평가 및 개선: 다중 병원 연구Multicenter Study Published on 2021-01-212022-09-10 Journal: BMC Medicine [Category] MERS, 치료기술, [키워드] (hypertension 95% CI 95% confidence interval age AUC baseline Biomarkers Blood Blood parameters Bristol C-reactive protein cardiovascular characteristic Cohort collected college Comorbidities Comorbidity COVID COVID-19 COVID-19 disease COVID-19 infection COVID-19 patients death detect diabetes disease Early warning score eight estimated glomerular filtration rate Ethnicity evaluate Evidence evidence of External filtration rate FIVE flow rate foundation glomerular filtration rate highlight hospital Hospital admission hypertension ICU identify IMPROVE improvement intensive care intensive care unit kidney Kidney diseases Measures National Early Warning Score National Health Service neutrophil neutrophil count neutrophil/lymphocyte ratio NEWS2 NEWS2 score NHS Norway outcome oxygen oxygen saturation parameter Patient physiological Prediction model question raise receiver receiver operating characteristic replicated respiratory Result risk risk stratification score Seven severe cases severe COVID-19 severe COVID-19 disease Severe COVID-19 Infection Sex Stratification supplemental oxygen supplementary material Tongji Hospital training transfer Trust university University College London urea validation cohort with COVID-19 Wuhan Wuhan, China [DOI] 10.1186/s12916-020-01893-3 PMC 바로가기 [Article Type] Multicenter Study
Allergen fragrance molecules: a potential relief for COVID-19알레르겐 향기 분자: COVID-19에 대한 잠재적 완화Research Article Published on 2021-01-212022-09-10 Journal: BMC Complementary Medicine and Therapies [Category] 신약개발, 치료법, [키워드] affected allergen analyzed Anti-viral fragrance molecules AutoDock AutoDock vina benzyl Benzyl Benzoate Benzyl Cinnamate Benzyl Salicylate best binding binding affinities binding affinity binding domain BRD2 bromodomain calculated carried China comparable coronavirus coronavirus SARS-CoV-2 COVID-19 cut-off default settings docking docking result dose drug expected FIVE flexible Fragrance allergen molecules function functional Galaxolide Health Host lowest macromolecules molecules MPro MVD nucleocapsid Prevent Protein protocol RBD Receptor binding domain reported Result Safe Salicylate SARS-CoV-2 Sclareol selected shown Spike protein Spread supplementary material target target proteins tested today treat Vaccine Virtual screening were used while [DOI] 10.1186/s12906-021-03214-4 PMC 바로가기 [Article Type] Research Article
Clinical characteristics of 14 COVID-19 deaths in Tianmen, China: a single-center retrospective studyResearch Article Published on 2021-01-202022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, MERS, [키워드] Acute kidney injury acute respiratory distress Admission age analyzed ARDS C-reactive protein cardiovascular disease Characteristics Chest CT chronic disease Chronic kidney disease clinical Clinical characteristics Comorbidities cough COVID-19 Critically ill patient CRP death deaths died Dyspnea elderly elevated epidemiological evaluated Factors Fever General symptom had more healthcare high risk Hospitalized hypertension increased risk Injury IQR Laboratory liver dysfunction lymphocyte median men Most patient Older onset of symptom organ dysfunction Patient radiological reduced Region reported resource Result Retrospective study SARS-CoV-2 SARS-CoV-2-infected patient severe pulmonary lesions significantly single-center supplementary material symptomatic syndrome the median Treatment with COVID-19 Wuhan [DOI] 10.1186/s12879-021-05770-z PMC 바로가기 [Article Type] Research Article
Environmental effects of stratospheric ozone depletion, UV radiation, and interactions with climate change: UNEP Environmental Effects Assessment Panel, Update 2020Perspectives Published on 2021-01-202022-10-28 Journal: Photochemical & photobiological sciences : Official journal of the European [Category] COVID-19, [키워드] acute respiratory syndrome Affect assessment change changes in coronavirus COVID-19 Effect Environment event extreme Interaction many cases Montreal Panel provide Radiation responsible SARS-CoV-2 supplementary material Sustainable Development Goals terrestrial Transmission ultraviolet United Nation [DOI] 10.1007/s43630-020-00001-x PMC 바로가기 [Article Type] Perspectives
Evaluation of convalescent plasma versus standard of care for the treatment of COVID-19 in hospitalized patients: study protocol for a phase 2 randomized, open-label, controlled, multicenter trial입원 환자의 COVID-19 치료에 대한 회복기 혈장 대 치료 표준 평가: 2상 무작위, 공개, 대조, 다기관 시험을 위한 연구 프로토콜Study Protocol Published on 2021-01-202022-09-10 Journal: Trials [Category] MERS, 임상, [키워드] 1:1 7-point ordinal scale Acute respiratory infection acute respiratory infections Administered Adult patients Analysis antibodies assigned cause caused center clinical trial Complete conducted contribute Controlled trial convalescent plasma Convalescent plasma (CP) COVID-19 COVID-19 infection COVID-19 pneumonia effective Efficacy Efficacy and safety enrolled etiology evaluate expected futility Hospitalized hospitalized patients immune response Immunotherapy include infected patient infected patients Interim Interim analyses intravenously invasive mechanical ventilation morbidity and mortality multicenter Multicenter trial Neutralizing antibodies Non-invasive Novel coronavirus Open-label option Ordinal Scale Patient patients hospitalized pharmacological primary endpoint proportion protocol Randomized Randomly receive respiratory Respiratory disease Sample size SARI SARS-CoV-2 Severe COVID-19 Infection Severe COVID-19 pneumonia severity Standard of care stratified Study protocol supplementary material the WHO therapeutic agent therapeutic agents Therapeutics Treatment treatment arm Trial registration Vaccine variety Viral viral disease with COVID-19 [DOI] 10.1186/s13063-020-05011-9 PMC 바로가기 [Article Type] Study Protocol