Drugs used during the COVID-19 first wave in Vitoria-Gasteiz (Spain) and their presence in the environmentVitoria-Gasteiz(스페인)의 COVID-19 1차 물결 동안 사용된 약물과 환경에서의 존재Article Published on 2022-05-102022-09-11 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] Administered affected Analysis Antiviral antiviral activity Azithromycin benefit cisatracurium city Concentration country COVID 19 COVID-19 COVID-19 pandemic defined detrimental effects dose drug Drug pollution first positive First wave healthcare professionals hospital Hydroxychloroquine ICUs intensive care unit intensive care units lAbel LC-q-Orbitrap Lopinavir LOPINAVIR AND RITONAVIR Lopinavir/ritonavir medium one health pandemic Patient patients pharmacoepidemiology positive potential risk proportion Quotient risk Ritonavir SARS-CoV2 selected drug selected drugs situation Spain target Target analysis. Treatment urgency Vitoria were used [DOI] 10.1016/j.scitotenv.2022.153122 PMC 바로가기 [Article Type] Article
Angiotensin-converting enzyme 2 (ACE2): Two decades of revelations and re-evaluation안지오텐신 전환 효소 2(ACE2): 20년 간의 폭로와 재평가Review Published on 2022-05-012022-09-11 Journal: Peptides [Category] Coronavirus, COVID19(2023년), SARS, 유전자 메커니즘, [키워드] ACE ACE2 acting Amino acid amyloid angiotensin Angiotensin II Angiotensin-converting enzyme angiotensin-converting enzyme-2 binding cardiovascular caused cell membrane cell type conversion coronavirus counterbalance COVID COVID-19 pandemic driving ectoenzyme enzyme event expressed Factor homology implicated Inflammatory mechanisms membrane protein neprilysin pathological conditions Pathologies pathology Pathways peptide peptides physiological producing Protective provide provided receptor regulate Renin renin-angiotensin system sACE2 SARS SARS virus SARS-CoV2 specificity susceptibility therapeutic target Transport Treatment Vascular Vasoactive Vasopeptidase. virus Zinc [DOI] 10.1016/j.peptides.2022.170766 PMC 바로가기 [Article Type] Review
High incidence of pulmonary thromboembolism in hospitalized SARS-CoV-2 infected patients despite thrombo-prophylaxis혈전 예방에도 불구하고 입원한 SARS-CoV-2 감염 환자에서 폐혈전색전증의 높은 발생률Observational Study Published on 2022-05-012022-09-11 Journal: Heart & lung : the journal of critical care [Category] COVID19(2023년), SARS, 임상, 치료기술, [키워드] Admission age caused Characteristics Coagulation Computed tomography coronavirus COVID-19 COVID-19 pneumonia CTPA D-dimer levels diagnosed Diagnosis died Endothelial cell endothelial cells European hospital hospitalised Hospitalization Hospitalized incidence infected patient Infection Injury median age much lower Negative PCR no differences no significant differences non-infected Observational cohort study one patient Patient patient mortality patients patients with COVID-19 patients with PE performed Pneumonia Pulmonary thromboembolism reported retrospective observational cohort study SARS-CoV-2 SARS-CoV-2 infected patient SARS-CoV-2 infected patients SARS-CoV2 Sex significant difference study period suspicion the patient those without PE Thromboembolism thrombosis thrombotic thrombotic complication Thrombotic complications two groups virus infection VTE [DOI] 10.1016/j.hrtlng.2022.02.003 PMC 바로가기 [Article Type] Observational Study
Ultrasensitive detection and quantification of viral nucleic acids with Raindance droplet digital PCR (ddPCR)Raindance droplet 디지털 PCR(ddPCR)을 사용한 바이러스 핵산의 초고감도 검출 및 정량화Article Published on 2022-05-012022-09-11 Journal: Methods (San Diego, Calif.) [Category] COVID19(2023년), SARS, 치료기술, [키워드] animal models Antiretroviral therapy approaches assays caused Cell Combination cure Cure research ddPCR detect Detection sensitivity diagnosis and monitoring digital PCR disease DNA and RNA Efficacy example highlighting HIV HIV prevention HIV-1 HIV-1 infection HIV-1 viral immunodeficiency virus infected individual infected individuals Infection Infectious disease Infectious diseases inhibition inhibitors Interpretation model systems NHP non-human primate nucleic acid Nucleic acid detection nucleic acids outcome platform predictor progression quantification quantitation Raindance reduced required Research reverse transcription rhesus macaque rhesus macaques RNA RT-ddPCR SARS-CoV2 sensitive Simian simian immunodeficiency virus SIV step tissue tissues Treatment treatment intervention treatment interventions viral DNA viral nucleic acid viral nucleic acid detection viral nucleic acids Viral reservoir virus viruses [DOI] 10.1016/j.ymeth.2021.04.025 PMC 바로가기 [Article Type] Article
Guillain Barre Syndrome as a Complication of COVID-19: Letter to the EditorComment Published on 2022-05-012023-07-09 Journal: The Canadian Journal of Neurological Sciences. Le [Category] COVID19(2023년), [키워드] COVID-19 GBS Guillain Barre syndrome SARS-CoV2 [DOI] 10.1017/cjn.2021.204 [Article Type] Comment
Antibody response to the COVID-19 ChAdOx1nCov-19 and BNT162b vaccines after temporary suspension of DMARD therapy in immune-mediated inflammatory disease (RESCUE)면역매개염증질환(RESCUE)에서 DMARD 치료를 일시적으로 중단한 후 COVID-19 ChAdOx1nCov-19 및 BNT162b 백신에 대한 항체 반응Randomized Controlled Trial Published on 2022-05-012022-09-11 Journal: RMD Open [Category] COVID19(2023년), MERS, SARS, 임상, 진단, 치료기술, 치료제, [키워드] Adult patients Antibody Response Antibody responses antirheumatic agents AstraZeneca AZ vaccine baseline biologic BNT162b Control control group control groups controls COVID-19 csDMARD dose Final first and second dose first dose first vaccination group groups IgG Immune-mediated immunogenicity inflammatory disease Messenger RNA multicentre not significantly different Patient Pfizer Protein randomised randomised controlled trial registration number response S1/S2 SARS-CoV-2 antibody SARS-CoV-2 IgG SARS-CoV2 second dose second vaccination Seroconversion seroconversion rate seroconversion rates significantly lower the antibody response the mean therapy titre titres U/mL vaccination Vaccine were measured [DOI] 10.1136/rmdopen-2022-002301 PMC 바로가기 [Article Type] Randomized Controlled Trial
The clinical impact of the Covid-19 pandemic first wave on patients with cystic fibrosis in New York뉴욕의 낭포성 섬유증 환자에 대한 Covid-19 대유행 1차 물결의 임상적 영향Multicenter Study Published on 2022-05-012022-09-12 Journal: Journal of cystic fibrosis : official journal of t [Category] MERS, 변종, 진단, [키워드] Antibody testing Anxiety Asymptomatic baseline Care CFTR Clinical characteristics clinical impact Complication conducted coronavirus COVID-19 COVID-19 case COVID-19 pandemic Cystic cystic fibrosis Depression determine diagnosed died fibrosis First wave Hospitalized IgG antibody multicenter New York objective pancreatic pandemic Patient patients with diabete PCR positive post-hoc analysis Prevalence prevalence of COVID-19 proportion Protective retrospective cohort study risk routine care SARS-CoV2 study cohort tested [DOI] 10.1016/j.jcf.2022.02.012 PMC 바로가기 [Article Type] Multicenter Study
Different chest CT scoring systems in patients with COVID-19: could baseline CT be a helpful tool in predicting survival in patients with matched ages and co-morbid conditions?Article Published on 2022-05-012023-07-06 Journal: Acta Radiologica (Stockholm, Sweden : 1987) [Category] COVID19(2023년), [키워드] inter-observer SARS-CoV2 score severity tomography [DOI] 10.1177/02841851211006316 PMC 바로가기
Repurposing tetracyclines for acute respiratory distress syndrome (ARDS) and severe COVID-19: a critical discussion of recent publications급성 호흡 곤란 증후군(ARDS) 및 중증 COVID-19에 대한 테트라사이클린 용도 변경: 최근 간행물에 대한 비판적 논의Article Published on 2022-05-012022-09-11 Journal: Expert opinion on investigational drugs [Category] COVID19(2023년), SARS, 신약개발, [키워드] activities acute respiratory distress acute respiratory distress syndrome addition antibiotic antiviral activity approach ARDS Area benefit Combination COVID-19 COVID-19 pandemic COVID-19 patients Critical doxycycline Drug repurposing Effectiveness Efficacy Evidence expert fibrosis immunomodulatory incyclinide inflammatory reaction initial limitation limitations Minocycline overcome pharmacological repurposing respiratory distress Respiratory distress syndrome safety profile SARS-CoV2 scarcity scientific evidence severe COVID-19 shown syndrome Tetracycline tetracyclines therapeutic potential therapy [DOI] 10.1080/13543784.2022.2054325 PMC 바로가기 [Article Type] Article
Greasing the inflammatory pathogenesis of viral pneumonias in diabetesReview Published on 2022-05-012023-07-07 Journal: Obesity Reviews [Category] COVID19(2023년), [키워드] adipocytes diabetes immunometabolism obesity SARS-CoV2 [DOI] 10.1111/obr.13415 PMC 바로가기 [Article Type] Review