X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease
Report
[키워드] acute respiratory syndrome
Affect
antiviral activity
applied
approved drug
assays
bind
binding
binding site
cause
caused
clinical trials
Compound
concentrations
conformational change
coronavirus
coronavirus disease
COVID-19
creating
drug
drug library
drug target
effective
experiment
expressed
functional
Genome
identify
inhibitors of SARS-CoV-2
M pro
nontoxic
performed
polyproteins
protease
Protein
reduction
representing
reveal
SARS-CoV-2
Science
Seven
Structure
structures
subsequent
target
tested
the disease
the SARS-CoV-2
Toxicity
treat
Viral proteins
viral replication
X-ray
[DOI] 10.1126/science.abf7945 PMC 바로가기 [Article Type] Report
[DOI] 10.1126/science.abf7945 PMC 바로가기 [Article Type] Report