Clinical Evaluation of the Abbott Alinity SARS-CoV-2 Spike-Specific Quantitative IgG and IgM Assays among Infected, Recovered, and Vaccinated GroupsAbbott Alinity SARS-CoV-2 스파이크 특이적 정량적 IgG 및 IgM 분석의 감염, 회복 및 백신 접종 그룹의 임상 평가Article Published on 2021-06-182022-09-11 Journal: Journal of Clinical Microbiology [Category] MERS, SARS, 진단, 치료법, [키워드] Abbott acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody Antibody Response Antibody responses Antibody test booster clinical clinical sensitivity Cohort collected Combination Containment coronavirus coronavirus disease Coronavirus infections COVID-19 COVID-19 vaccines cross-reactivity dampened response dose group Health IgG IgG and IgM IgM immune responses Immunity immunoassays individual individuals Infection Laboratory nucleocapsid pandemic participant Quantitative recovered respiratory response SARS-CoV-2 sensitivity serologic assay Serological assay serological response serology assay serology assays severe acute respiratory syndrome Coronavirus significant increase spike Spike protein unique utility vaccination Vaccine while [DOI] 10.1128/JCM.00388-21 PMC 바로가기 [Article Type] Article
Cross-Reactivity of Two SARS-CoV-2 Serological Assays in a Setting Where Malaria Is Endemic말라리아가 풍토병인 환경에서 두 SARS-CoV-2 혈청학적 분석의 교차 반응성Article Published on 2021-06-182022-09-11 Journal: Journal of Clinical Microbiology [Category] MERS, SARS, 말라리아, 진단, 치료법, [키워드] Abbott alleviate antibody Antibody binding Architect assays association avidity Concentration COVID-19 Critical cross-reactivity Endemic Euroimmun False positive False positives IgG IgG level indicated malaria moderate Nigeria PCR PCR-positive plasma Plasmodium Plasmodium falciparum Plasmodium falciparum infection positive Previous studies previous study Protein reduced SARS-CoV-2 SARS-CoV-2 nucleocapsid SARS-CoV-2 patient SARS-CoV-2 patients Serological assay serological assays serology setting significantly higher tested urea urea concentration urea concentrations was performed WASH [DOI] 10.1128/JCM.00514-21 PMC 바로가기 [Article Type] Article
The landscape of antibody binding in SARS-CoV-2 infectionSARS-COV-2 감염에서 항체 결합의 풍경Research Article Published on 2021-06-182022-08-13 Journal: PLoS Biology [Category] Biochemistry, MERS, SARS, 진단, 치료법, [키워드] Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus antibody Antibody binding B cell epitope B cell epitopes binding convalescent coronavirus correlated CoV proteins COVID-19 CoVs cross-reactivity develop diagnostic Diagnostic accuracy diagnostics ELISA enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay epitope Epitopes homologous human CoVs human sera humoral immunogen humoral immunogens identify illness Illness severity induce membrane naïve nucleocapsid occurred ORF3a ORF8 protein ORF8 proteins other coronavirus other coronaviruses pandemic peptide peptide sequences Profiling Protein Proteins proteome reactive reactivity respiratory robust antibody response robust antibody responses SARS-CoV-2 SARS-CoV-2 epitope SARS-CoV-2 epitopes SARS-COV-2 infection SARS-CoV-2 proteome sequence severity the SARS-CoV-2 Therapeutics ultradense peptide microarray Vaccines [DOI] 10.1371/journal.pbio.3001265 PMC 바로가기 [Article Type] Research Article
A broadly cross-reactive monoclonal antibody against hepatitis E virus capsid antigenArticle Published on 2021-06-152023-08-29 Journal: Applied Microbiology and Biotechnology [Category] E형 간염, [키워드] batHEV Cell-free synthesis cross-reactivity cvHEV hepatitis E virus HEV-1 HEV-2 HEV-3 HEV-4 HEV-7 monoclonal antibody ratHEV [DOI] 10.1007/s00253-021-11342-7 PMC 바로가기
Cross-Reactive SARS-CoV-2 Neutralizing Antibodies From Deep Mining of Early Patient Responses초기 환자 반응의 심층 마이닝에서 교차 반응성 SARS-CoV-2 중화 항체Immunology Published on 2021-06-152022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 변종, 진단, [키워드] affected antibodies antibody antibody repertoire Antibody Response approach B cell B.1.1.28 B.1.1.7 B.1.351 BCR binding binding epitope blocking antibody Brazil conserved convergence COVID-19 cross-reactivity deep described epitope Epitopes highlight hospitalized COVID-19 patient hospitalized COVID-19 patients independent monoclonal antibodies monoclonal antibody Mutation Neutralizing antibodies neutralizing antibody occur passive immunization Patient phage display RBD binding receptor reduced reported response reveal SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 variants sensitivity sequence sequences Sequencing South Africa study group the RBD unlikely Vaccine Viral viral variant Viral variants [DOI] 10.3389/fimmu.2021.678570 PMC 바로가기 [Article Type] Immunology
Glycan reactive anti-HIV-1 antibodies bind the SARS-CoV-2 spike protein but do not block viral entryArticle Published on 2021-06-142022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, SARS, [키워드] ADE antibodies antibody Antibody titer Antibody-dependent enhancement Antigen binding block viral entry contribute COVID-19 Critical cross-reactive antibody cross-reactivity displaying ELISA experiment expressing glycan glycosylation gp120 HIV-1 immune response immunoassays immunoreactivity implication Infection interfere Interpretation Microbiology motif Neutralizing nine pseudovirus reactive receptor engagement SARS-CoV-2 SARS-CoV-2 S SARS-CoV-2 spike glycoprotein SARS-CoV-2 spike protein selected serological assays Spike protein Spike proteins the SARS-CoV-2 therapeutic unlikely vaccine immunogen Virology virus Virus neutralization [DOI] 10.1038/s41598-021-91746-7 PMC 바로가기 [Article Type] Article
Prospective Assessment of SARS-CoV-2 Seroconversion (PASS) study: an observational cohort study of SARS-CoV-2 infection and vaccination in healthcare workersSARS-COV-2 SEROCONVERSION (PASS) 연구의 전향 적 평가 : 의료 근로자의 SARS-COV-2 감염 및 예방 접종에 대한 관찰 코호트 연구Study Protocol Published on 2021-06-092022-09-01 Journal: BMC Infectious Diseases [Category] MERS, SARS, 진단, [키워드] Affect Analysis Anti-spike antibody assessment Asymptomatic baseline clinical response Cohort Complete conducted coronavirus coronavirus disease Coronavirus disease 2019 CoV covariates COVID-19 COVID-19 disease COVID-19 disease course cross-reactivity cytokine production determine develop disease symptoms evaluate Frequency glycoprotein HCoV HCoV-229E HCoV-HKU1 HCoV-NL63 HCoV-OC43 HCoVs HCWs healthcare healthcare worker HKU1 human coronavirus IgG antibodies IgM and IgG immune response immune responses Immune-response immunological individual Infection intensity Killer cell magnitude mononuclear cell natural natural killer cell NL63 number of infected Observational cohort study OC43 pandemic coronavirus participant pauci-symptomatic PBMCs peptide peptide pool performed Peripheral blood Peripheral blood mononuclear cells positive Prospective Prospective Study questionnaire receive respiratory Respiratory disease Respiratory illness SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 PCR SARS-CoV-2 PCR testing SARS-CoV-2 vaccination SARS-CoV-2 vaccine seroconvert serology analysis severe respiratory illness severity Spike proteins supplementary material Symptom T cell T cell activation T cell response T cell responses tested the SARS-CoV-2 the spike protein vaccination Vaccine viral respiratory with COVID-19 [DOI] 10.1186/s12879-021-06233-1 PMC 바로가기 [Article Type] Study Protocol
Diagnostic performance of four SARS-CoV-2 antibody assays in patients with COVID-19 or with bacterial and non-SARS-CoV-2 viral respiratory infectionsCOVID-19 환자 또는 박테리아 및 비 SARS-CoV-2 바이러스 호흡기 감염 환자에서 4가지 SARS-CoV-2 항체 분석의 진단 성능Comparative Study Published on 2021-06-092022-09-10 Journal: European Journal of Clinical Microbiology & Infect [Category] MERS, SARS, 진단, 치료기술, [키워드] anti-SARS-CoV-2 anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody antibody assays Bacterial bacterial and viral infections Bacterial infection Bacterial infections bacterial respiratory infections benefit Cell Chlamydia Control coronavirus COVID-19 COVID-19 patients cross-reactivity disease ELISA ELISAs enzyme-linked immunosorbent assay enzyme-linked immunosorbent assays epidemiological studies Epidemiological study Euroimmun Evidence evidence of expressing false-positive result fatal disease highest IgA IgG Interpretation Legionella pneumophila Mycoplasma pneumoniae Patient patients with COVID-19 pneumoniae positive respiratory Respiratory disease respiratory infections SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 spike protein sensitivity sera serological evidence Specificities specificity Spike protein supplementary material T cells the SARS-CoV-2 vaccine response vaccine responses Viral viral infection viral infections viral respiratory viral respiratory infection Vircell vulnerable patients [DOI] 10.1007/s10096-021-04285-4 PMC 바로가기 [Article Type] Comparative Study
Antibody Responses to SARS-CoV-2 Following an Outbreak Among Marine Recruits With Asymptomatic or Mild Infection무증상 또는 경증 감염이 있는 해병 모집단의 발병 후 SARS-CoV-2에 대한 항체 반응Immunology Published on 2021-06-092022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, 치료기술, 치료법, [키워드] Adults age antibodies Asymptomatic asymptomatic infection Betacoronavirus circulating Cohort comparable COVID-19 cross-reactivity disease domain Endemic enrolled focus healthy Humoral response humoral responses IgA antibodies IgA antibody IgG IgG antibodies IgG antibody Infection investigated Longitudinal studies longitudinal study Mild Mild disease mild SARS-CoV-2 infection mild symptoms Multiplex assay neutralization activity Neutralizing activity no decrease nucleocapsid outbreak participant polyclonal Population positive positive correlation Protein RBD recruit remained reported respiratory Respiratory illness response S protein S proteins SARS-CoV-2 SARS-CoV-2 IgG SARS-COV-2 infection SARS-CoV-2 RBD SARS-CoV-2 spike sera serological response significantly spring tested young adults zoonotic [DOI] 10.3389/fimmu.2021.681586 PMC 바로가기 [Article Type] Immunology
Developing a Paper-Based Antigen Assay to Differentiate between Coronaviruses and SARS-CoV-2 Spike Variants코로나바이러스와 SARS-CoV-2 스파이크 변이체를 구별하기 위한 종이 기반 항원 분석 개발Article Published on 2021-06-082022-09-11 Journal: Analytical Chemistry [Category] SARS, 변종, [키워드] Antigen binding build Concentration COVID-19 cross-reactivity Developing diagnostics Factors Final flexible fraction Fractions global pandemic HCoV HCoV-229E HCoV-OC43 HKU1 human saliva human serum immunoassay less lowest media pandemic PCR produced provide robust RT-PCR SARS-CoV-1 SARS-CoV-2 significant effect spike Spike protein Spike proteins test line time-consuming unique various coronaviruses viruses Wuhan Wuhan, China [DOI] 10.1021/acs.analchem.0c05438 PMC 바로가기 [Article Type] Article