Differences and similarities between SARS-CoV and SARS-CoV-2: spike receptor-binding domain recognition and host cell infection with support of cellular serine proteasesReview Published on 2020-07-312022-10-29 Journal: Infection [Category] COVID-19, MERS, SARS, [키워드] Activation acute respiratory syndrome appear cellular contagious coronavirus Coronavirus-2 Coronaviruses develop difference effective furin host cell immune Infection Intervention mortality rates neutralizing antibody novel outbreak pandemic Pathogenesis pathogenicity protease Receptor binding domain reported SARS-CoV SARS-CoV-2 SARS-CoV-2 infected patient SARSCoV-2 serine protease similarity spike receptor-binding domain Support Surveillance [DOI] 10.1007/s15010-020-01486-5 PMC 바로가기 [Article Type] Review
Hydroxychloroquine and Coronavirus Disease 2019: A Systematic Review of a Scientific FailureSpecial Issue on the COVID-19 Pandemic Published on 2020-07-312022-10-28 Journal: Rambam Maimonides Medical Journal [Category] COVID-19, [키워드] administration adopted case sery China Chloroquine clinical evidence clinical study cohorts coronavirus coronavirus disease Course COVID-19 death effort Europe Evidence failure HCQ Hydroxychloroquine mortality rates no significant effect non-randomized observational studies observational study pandemic Prevent Prophylactic Prophylaxis provided Randomized controlled trial RCT RCTs Result review screened therapeutic treat Treatment Trial USA [DOI] 10.5041/RMMJ.10416 PMC 바로가기 [Article Type] Special Issue on the COVID-19 Pandemic
Hyponatremia in Infectious Diseases—A Literature ReviewReview Published on 2020-07-232022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS, [키워드] Bacterial infections community-acquired pneumonia coronavirus disease COVID-19 described diagnostic diagnostic value Diseases disorder eligible etiology Hospitalization human organism hyponatremia inclusion criteria Infection infections Infectious diseases item less literature mechanism Mortality mortality rates outcomes pathogen Patient patient cohort Prognosis Reporting review screened selected serum sodium concentration syndrome of inappropriate antidiuretic hormone secretion threshold Web of Science [DOI] 10.3390/ijerph17155320 PMC 바로가기 [Article Type] Review
Healthcare Capacity, Health Expenditure, and Civil Society as Predictors of COVID-19 Case Fatalities: A Global AnalysisPublic Health Published on 2020-07-032022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, [키워드] 95% confidence interval Analysis association Bank Capacity civil society confirmed case confirmed cases country covariates COVID-19 COVID-19 patient database death decrease determine effective evaluate fatality Government greater growth Health healthcare healthcare capacity healthcare expenditure ICU increase in Infection Johns Hopkins University mitigate Mortality mortality rates multidimensional National negative Non-communicable disease outcomes population density Preliminary data public health public health measure Regression Regression model Research Society Space statistical significance used data variable was related was used [DOI] 10.3389/fpubh.2020.00347 PMC 바로가기 [Article Type] Public Health
Reducing mortality and morbidity in patients with severe COVID-19 disease by advancing ongoing trials of Mesenchymal Stromal (stem) Cell (MSC) therapy — Achieving global consensus and visibility for cellular host-directed therapiesEditorial Published on 2020-07-012022-10-05 Journal: International Journal of Infectious Diseases [Category] SARS, 신약개발, 임상, [키워드] agency antiviral drug blueprint cause caused Cell cellular circulating clinical clinical trial Combination combinations Community Consensus COVID-19 COVID-19 mortality death death rate disease effective HDTs Host host-directed therapy immune Inflammatory response initiated long-term functional disability MERS-CoV morbidity Mortality mortality rates MSC MSC therapy MSCs novel coronavirus disease ongoing trial pandemic pathogen pathogenesis of SARS-CoV-2 Patient reducing mortality regimen registry reported Repurposed drug severe COVID-19 disease specific treatment STEM the WHO therapeutic interventions therapy Treatment treatment trial Trial turn underlie Vaccine WHO WHO ICTRP World Health Organization [DOI] 10.1016/j.ijid.2020.05.040 [Article Type] Editorial
COVID-19 Virulence in Aged Patients Might Be Impacted by the Host Cellular MicroRNAs Abundance/ProfileOrginal Article Published on 2020-06-282022-10-28 Journal: Aging and Disease [Category] COVID-19, [키워드] aging Antiviral effect approach cellular miRNA coding region contagiousness coronavirus Coronavirus disease 2019 correlated COVID-19 Diseases effective Factor Genome global pandemic Health Organization Host human miRNA identify in silico analysis in vitro in vivo individual induce involved isolate isolates KEGG KEGG pathway analysis lack measure microRNA MicroRNAs miRNA miRNA targets Mortality mortality rates patient population potential therapeutic targets public health crisis recent regions severity Signaling signaling pathway suggested target targets treatment strategy underlying conditions unique UTR viral genome WHO Wuhan [DOI] 10.14336/AD.2020.0428 PMC 바로가기 [Article Type] Orginal Article
A 95-year-old patient with unexpected coronavirus disease 2019 masked by aspiration pneumonia: a case reportCase Report Published on 2020-06-232022-10-30 Journal: Journal of Medical Case Reports [Category] COVID-19, SARS, [키워드] acute respiratory syndrome affected aspiration pneumonia Case report Chest China clinical history Complication Computed tomography Contact coronavirus disease Coronavirus-2 COVID-19 defined Dementia develop diagnosing Diagnosis diagnostic Dysphagia elderly epidemiological link expected feature greater Health highest highlight hospitals individual Infection infectious risk initial Italy mortality rates multiple comorbidities Older older adult pandemic disease Patient patients with comorbidity Pneumonia professional reduced SARS-CoV-2 Spread susceptible Vascular [DOI] 10.1186/s13256-020-02432-7 PMC 바로가기 [Article Type] Case Report
ACE2 and TMPRSS2 variants and expression as candidates to sex and country differences in COVID-19 severity in ItalyResearch Paper Published on 2020-06-152022-10-28 Journal: Aging (Albany NY) [Category] COVID-19, [키워드] ACE2 candidate Cohort Comorbidities coronavirus disease country Course COVID-19 COVID-19 severity database death disease East Asians European Evidence experimental validation expression expression level Frequency Gene Expression Genes genetic component Genetic variant genetic variants highest individual Italian Italy large patient cohorts Male sex medical need mortality rates Older age outbreak polymorphism Prognostic marker SARS-CoV-2 searched Sex TMPRSS2 TMPRSS2 level variant viral infection were used while [DOI] 10.18632/aging.103415 PMC 바로가기 [Article Type] Research Paper
Nutritional Support in Coronavirus 2019 DiseaseProtocol Published on 2020-06-122022-10-30 Journal: Medicina [Category] COVID-19, SARS, [키워드] activity approach calculated Care Chinese Chinese Medical Association clinical coronavirus COVID-19 Diagnosis Enteral Epidemic European implementation intensive care Malnutrition mortality rates nutrition nutrition support nutritional status observation Parenteral patients with COVID-19 recommendation reduction SARS-CoV-2 Society therapy Wuhan [DOI] 10.3390/medicina56060289 PMC 바로가기 [Article Type] Protocol
Time-to-Death approach in revealing Chronicity and Severity of COVID-19 across the WorldResearch Article Published on 2020-05-122022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] absence approach China Concordance coronavirus disease country COVID-19 COVID-19 infection death duration of exposure effective elapsed finding France Generalized linear model Germany help information Iran Italy Mortality mortality rate mortality rates outbreak pandemic predict predicted raise Registered selected Seven severity Spain Spread United Kingdom Vaccine was used were used Wuhan, China [DOI] 10.1371/journal.pone.0233074 PMC 바로가기 [Article Type] Research Article