MALDI-ToF protein profiling as a potential rapid diagnostic platform for COVID-19
Research article
Published on
Journal: Journal of Mass Spectrometry and Advances in the Clinical Lab [Category] 바이오마커, 변종, 진단,
Journal: Journal of Mass Spectrometry and Advances in the Clinical Lab [Category] 바이오마커, 변종, 진단,
[키워드] liquid chromatography mass spectrometry
ACE2angiotensin-converting enzyme 2
Analysis
analyzed
angiotensin-converting enzyme 2
area under the curve
Asymptomatic
AUCarea under the curve
Biomarker
Cohort
Concordance
controls
Coronavirus disease 2019
COVID-19
COVID-19 pandemic
COVID-19 testing
COVID-19coronavirus disease 2019
CT
cycle threshold
demonstrated
develop
diagnostic
Diagnostic method
dithiothreitol
DTTdithiothreitol
E Proteinenvelope protein
Emergency use authorization
envelope protein
EUAemergency use authorization
FDAFood and Drug Administration
Food and Drug Administration
human donor
human serum
IgAimmunoglobulin A
IgGimmunoglobulin G
IgMimmunoglobulin M
immunoglobulin A
Immunoglobulin G
immunoglobulin M
immunoglobulins
inactivated
LC-MS
limit of detection
limitation
LoDlimit of detection
M Proteinmembrane protein
MALDI-ToF MSmatrix-assisted laser desorption/ionization-time of flight mass spectrometry
matrix-assisted laser desorption/ionization-time of flight mass spectrometry
membrane protein
N Proteinnucleocapsid protein
nasopharyngeal
Nasopharyngeal swab
nasopharyngeal swabs
Non-invasive
NPnasopharyngeal
nucleocapsid protein
pilot study
platform
positive individuals
Protein
proteome
RBDReceptor Binding Domain
receiver operating characteristic
Receptor binding domain
Reverse transcriptase quantitative polymerase chain reaction
Ribonucleic acid
RNARibonucleic acid
ROCreceiver operating characteristic
RT-qPCR
S Proteinspike protein
Saliva
SARS-CoV-2
SARS-CoV-2 strains
SARS-CoV-2 virus
SARS-CoV-2severe acute respiratory syndrome coronavirus 2
sensitivity
severe acute respiratory syndrome coronavirus 2
specificity
specimen
Spike protein
VEPviral envelope protein
viral envelope protein
WHOWorld Health Organization
with COVID-19
World Health Organization
[DOI] 10.1016/j.jmsacl.2021.09.001 [Article Type] Research article
[DOI] 10.1016/j.jmsacl.2021.09.001 [Article Type] Research article