Tocilizumab and Systemic Corticosteroids in the Management of Patients with COVID-19: A Systematic Review and Meta-AnalysisCOVID-19 환자 관리에서 토실리주맙과 전신 코르티코스테로이드: 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-09-012022-09-12 Journal: International Journal of Infectious Diseases [Category] SARS, 진단, [키워드] 95% confidence interval adjusted association Combination coronavirus COVID-19 COVID-19 patients data extraction disease effective Efficacy estimate Health lower mortality mortality rate New coronavirus not differ outcome performed randomized trial Record review risk risk of bia SCT searched severe COVID-19 Standard of care study outcomes subject systemic systemic corticosteroid systemic corticosteroid therapy TCZ therapy Tocilizumab Treatment were used [DOI] 10.1016/j.ijid.2021.07.021 PMC 바로가기 [Article Type] Meta-Analysis
Saliva for molecular detection of SARS-CoV-2 in school-age children학령기 아동의 SARS-CoV-2 분자 검출용 타액Observational Study Published on 2021-09-012022-09-11 Journal: Clinical microbiology and infection : the official [Category] MERS, SARS, 임상, 진단, 치료기술, [키워드] 95% CI 95% confidence interval Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age carried children Concordance coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cycle cycle threshold demonstrated determine diagnostic Diagnostic accuracy Dubai Gender Kappa coefficient male molecular nasopharyngeal Nasopharyngeal swab Negative predictive value not differ NP swab participant positive predictive values presenting provided RdRP RdRp gene recruited reported respiratory reverse transcriptase reverse transcriptase PCR RT-PCR Saliva saliva samples SARS-CoV-2 SARS-CoV-2 RT-PCR significantly higher specificity specimen Standard deviation Swab tested threshold United Arab Emirates virus detection [DOI] 10.1016/j.cmi.2021.02.009 PMC 바로가기 [Article Type] Observational Study
Impact of the COVID-19 pandemic on emergency medical service response to out-of-hospital cardiac arrests in Taiwan: a retrospective observational studyObservational Study Published on 2021-09-012022-10-05 Journal: Emergency medicine journal : EMJ [Category] SARS, 임상, [키워드] affected age analysed automated Cardiac arrest Cardiopulmonary circulation COVID-19 COVID-19 outbreak COVID-19 pandemic Defibrillation despatch discharge Emergency Impact Infectious diseases neurological function not differ outcome Patient Prehospital care protocol recorded Resuscitation retrospective risk SARS Sex significantly Support survival [DOI] 10.1136/emermed-2020-210409 PMC 바로가기 [Article Type] Observational Study
High-Dose Oral and Intravenous Rifampicin for the Treatment of Tuberculous Meningitis in Predominantly Human Immunodeficiency Virus (HIV)-Positive Ugandan Adults: A Phase II Open-Label Randomized Controlled Trial주로 인간 면역 결핍 바이러스 (HIV)-양성 우간다 성인에서 결핵성 수막염의 치료를위한 고용량 경구 및 정맥 내 리팜피신 : 2 상 공개 라벨 무작위 대조 시험Major Articles and Commentaries Published on 2021-09-012022-09-06 Journal: Clinical Infectious Diseases: An Official Publicat [Category] Communicable Disease, [키워드] 95% confidence interval Administered Adults Adverse adverse events AUC C max CD4 cerebrospinal fluid Concentration Controlled CSF current dose enrolled event geometric geometric mean High-dose HIV Human Human immunodeficiency virus immunodeficiency virus IMPROVE inhibitory concentration intensified therapy International interquartile range intravenous intravenously majority median Meningitis minimal inhibitory concentration not differ occurred Open-label open-label trial oral outcome participant Participants Patient patients performed pharmacokinetic phase PK data plasma Primary outcome Primary outcomes Randomized regimen Result rifampicin Safe serum Standard of care Standard-of-care sustained TBM therapeutic Toxicity Trial Tuberculosis tuberculous tuberculous meningitis undetectable with HIV would increase [DOI] 10.1093/cid/ciab162 PMC 바로가기 [Article Type] Major Articles and Commentaries
Standard prophylactic versus intermediate dose enoxaparin in adults with severe COVID-19: A multi-center, open-label, randomized controlled trialRandomized Controlled Trial Published on 2021-09-012022-10-05 Journal: Journal of thrombosis and haemostasis : JTH [Category] SARS, 임상, [키워드] 1:1 95% confidence interval all-cause mortality Anticoagulant anticoagulation arterial assigned bleeding Blood Blood coagulation Chi-square Coagulopathy conducted Coronavirus disease 2019 COVID-19 COVID-19 disease COVID-19 severity Cox proportional hazard death demonstrated dose enoxaparin Evidence females hazard ratio Hospitalized ICU intensive care intention-to-treat population intermediate dose Laboratory Major major bleeding male Mortality no significant difference not differ occurred Odds ratio Open-label outcome Patient Primary outcome Prophylactic prophylactic dose randomization Randomized controlled trial Randomly receive remains uncertain secondary severe COVID-19 significantly Standard Standard dose therapy thrombosis treated Venous Thromboembolism Venous thrombosis with COVID-19 [DOI] 10.1111/jth.15450 PMC 바로가기 [Article Type] Randomized Controlled Trial
Risk for Acquiring Coronavirus Disease Illness among Emergency Medical Service Personnel Exposed to Aerosol-Generating ProceduresResearch Published on 2021-09-012022-10-31 Journal: Emerging Infectious Diseases [Category] COVID-19, SARS, [키워드] acute respiratory syndrome aerosol transmission aerosol-generating procedure aerosol-generating procedures AGP Cardiac arrest conditions conducted coronavirus coronavirus disease COVID-19 COVID-19 incidence COVID-19 infection COVID-19 patient Emergency Emergency medical services emergency treatment Health occupations illness Infection investigated involved King maintain medical first responders not differ occurred Patient procedure public health public health readiness respiratory infections responders retrospective cohort risk SARS-CoV-2 service severe acute respiratory syndrome coronavirus 2 stratified USA viruses Washington zoonoses [DOI] 10.3201/eid2709.210363 PMC 바로가기 [Article Type] Research
Negative effects of iodine-based contrast agent on renal function in patients with moderate reduced renal function hospitalized for COVID-19Research Published on 2021-08-312022-10-28 Journal: BMC Nephrology [Category] COVID-19, MERS, [키워드] 30-Day mortality acute renal failure administration Affect Analysis Computed tomography contrast agent Contrast-induced acute renal failure COVID COVID − 19 COVID-19 creatinine death defined disease Effect evaluated Factor FIVE Follow-up Frequency glomerular filtration rate group hospital Hospitalized indication Iodinated contrast negative not differ P-creatinine Patient patients patients died patients with moderate Pearson reduced renal renal function renal replacement therapy Result was measured [DOI] 10.1186/s12882-021-02469-w PMC 바로가기 [Article Type] Research
COVID-19 pandemic: Impact on the management of patients with hepatocellular carcinoma at a tertiary care hospitalResearch Article Published on 2021-08-262022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] Admission age analyzed Care change Clinical data Contact COVID-19 diagnose diagnostic procedures Effect HCC HCC patient healthcare Hepatocellular carcinoma hospital Impact impaired liver function implementation increase in initiated lowest majority male management median negatively affected New not differ not different number one patient outcome Patient Patient care patients reduced resources Result Treatment Vienna while [DOI] 10.1371/journal.pone.0256544 PMC 바로가기 [Article Type] Research Article
Moderators of changes in smoking, drinking and quitting behaviour associated with the first COVID‐19 lockdown in EnglandResearch Report Published on 2021-08-252022-10-28 Journal: Addiction (Abingdon, England) [Category] COVID-19, MERS, SARS, [키워드] 95% confidence interval adjusted odds ratio Adults age alcohol alcohol reduction change changes in collected COVID‐19 COVID‐19 Drinking England finding group groups increase independent variable less lockdown measurement Moderator not differ Older outcome participant Prevalence quit attempts reduction relative SARS‐CoV‐2 setting Sex significant changes in significant increase significant increases in significantly smoker smoking smoking cessation Support women [DOI] 10.1111/add.15656 PMC 바로가기 [Article Type] Research Report
Physical and mental health impacts of the COVID-19 pandemic among college students who are undocumented or have undocumented parentsResearch Article Published on 2021-08-212022-10-28 Journal: BMC Public Health [Category] Coronavirus, MERS, SARS, [키워드] affected analyzed collected COVID COVID-19 COVID-19 pandemic detrimental early stage Effects examined Health Impact Mental mental health Mixed-status families negative not differ pandemic parent parents physical resource Result separation student supplementary material Undocumented immigrants widespread young adults [DOI] 10.1186/s12889-021-11606-x PMC 바로가기 [Article Type] Research Article