SARS-CoV-2 vaccine booster in solid organ transplant recipients previously immunised with inactivated versus mRNA vaccines: A prospective cohort studyArticle Published on 2022-12-012022-10-06 Journal: Lancet Reg Health Am [Category] 진단, [키워드] age All participant anti-SARS-CoV-2 BNT162b2 BNT162b2 vaccine booster Care cohort study CoronaVac COVID-19 determine dose effective end point General population groups Heterologous heterologous vaccine homologous humoral immune response IFN-γ IgG antibody IL-2 inactivated kidney liver median Medicine more difficult mRNA mRNA vaccine neutralising antibody not differ of BNT162b2 outcome Patient priming proportion Prospective prospective cohort study recipient recipients Red SARS-CoV-2 SARS-CoV-2 vaccine School secondary secreting significantly significantly higher solid organ solid organ transplant SOT T-cell T-cell responses vaccination Vaccine vaccine immunogenicity women [DOI] 10.1016/j.lana.2022.100371 PMC 바로가기 [Article Type] Article
Managing ANCA-associated vasculitis during COVID-19 pandemic: a single-center cross-sectional studyArticle Published on 2022-12-012022-11-15 Journal: Rheumatology International [Category] 바이오마커, 진단, [키워드] Active disease ANCA-associated vasculitis Care clinical manifestations Cohort conducted COVID-19 COVID-19 infection COVID-19 severity Critical cross-sectional Cyclophosphamide death demographic died Disease activity Features Follow-up General population Immunosuppressant increased risk India Infection managing moderate non-COVID-19 patient not differ ocular outcome Patient patients patients died predicted receiving regimen required risk of COVID-19 rituximab SARS-CoV-2 severity single-center Supplemental oxygen therapy the patient Treatment Univariate analysis Vasculitis [DOI] 10.1007/s00296-022-05177-2 PMC 바로가기
IL-6 signalling biomarkers in hospitalised patients with moderate to severe SARS-CoV-2 infection in a single centre study in SwedenResearch article Published on 2022-11-012022-10-05 Journal: Cytokine [Category] SARS, 바이오마커, [키워드] addition analysed baseline Biomarker Biomarkers C-reactive protein (CRP Care classical correlated correlation COVID-19 COVID-19 disease severity COVID-19 pandemic CRP Cytokine/IL-6 defined demonstrated Epidemiology First wave glycoprotein group groups hospital Hospital admission hospitalised patient IL-6 IL-6 pathway IL-6 receptor immune immune response Infection Inflammation intensive care involved Level longitudinal cohort study marker moderate moderate-severe Mortality not differ pathogen pathway Pathways Patient patients with moderate plasma Potential difference Respiratory Support Result severe COVID-19 severe SARS-CoV-2 sgp130 significantly sIL-6R with COVID-19 [DOI] 10.1016/j.cyto.2022.156020 [Article Type] Research article
Examining the impact of trimester of diagnosis on COVID-19 disease progression in pregnancyResearch article Published on 2022-11-012022-10-05 Journal: American journal of obstetrics & gynecology MFM [Category] 치료기술, [키워드] Affect Asymptomatic Blood COVID-19 diagnosis COVID-19 disease COVID-19 disease progression COVID-19 disease severity COVID-19 illness COVID-19 in pregnancy COVID-19 infection criteria Critical defined develop diagnosed with COVID-19 Diagnosis Disease progression evaluate the effect evaluated Examining Features Frequency had more Hispanic hospital Hospital admission Infection initially asymptomatic patient Maternal morbidity Mild mild infection Mild symptom moderate morbidity Neonatal Neonatal morbidity no significant difference not differ Older outcome outcomes pandemic Patient patients patients with asymptomatic Positive test Pregnancy pregnant patient pregnant patients progression prospective cohort study SARS-CoV-2 SARS-CoV-2 in pregnancy severity Stillbirth stratified symptomatic infection symptomatic patient Symptoms the timing trimester of infection Universal was performed [DOI] 10.1016/j.ajogmf.2022.100728 [Article Type] Research article
Exhaled breath SARS-CoV-2 shedding patterns across variants of concernArticle Published on 2022-10-012022-11-16 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 변종, [키워드] Alpha Antigen breath Cochran Q test Cohort comparable confidence interval COVID-19 Exhaled Breath Infection infections interquartile range IQR median nasopharyngeal nasopharynx not differ Patient peak peaked performed polymerase chain qPCR Quantitative SARS-CoV-2 SARS-COV-2 infection Test variants variants of concern viral shedding Wilcoxon-Mann-Whitney [DOI] 10.1016/j.ijid.2022.07.069 PMC 바로가기
Outcome of SARS-CoV-2 infection among patients with common variable immunodeficiency and a matched control group: A Danish nationwide cohort studyArticle Published on 2022-09-232022-11-16 Journal: Frontiers in Immunology [Category] SARS, 치료기술, [키워드] age calculate Clinical outcome cohort study common variable immunodeficiency (CVID) conducted Contact control group Coronavirus-2 Course COVID-19 Cox regression CVID death detectable estimate Gender General population groups hospital Immunity immunodeficiency in both groups inborn errors of immunity (IEI) incidence rate increased risk individual Infection mechanical ventilation not differ Novel coronavirus outcome Patient Re-infection risk Sample size SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination severe adult respiratory coronavirus-2 (SARS-CoV-2) severe novel coronavirus 2019 (COVID-19). severity the timing was used [DOI] 10.3389/fimmu.2022.994253 PMC 바로가기
Simultaneous Detection of RIG-1, MDA5, and IFIT-1 Expression Is a Convenient Tool for Evaluation of the Interferon-Mediated ResponseArticle Published on 2022-09-212022-11-15 Journal: Viruses [Category] SARS, 유전자 메커니즘, 치료기술, 치료제, [키워드] A549 cell acute phase assumed both virus clinical Course cytosolic cytosolic sensors detection disease onset Disease progression donors elevated evaluated expression Genes H3N2 immune response in vitro in vitro transcribed RNAs influenza A influenza A virus inhibit interferon-stimulated gene interferons ISGs MDA5 Mild-to-moderate mRNA expression mRNA level multiple mechanism multiplex not differ observation onset of symptoms pathogenesis of SARS-CoV-2 patients with influenza post infection qPCR qPCR assay remained response RNA RNAs SARS-CoV-2 SARS-CoV-2 patient Signaling Simultaneous SOCS-1 the disease transcribed transfected with type I virus White blood cell White blood cells worsening [DOI] 10.3390/v14102090 PMC 바로가기
Impact of obstructive sleep apnea on clinical outcomes in patients hospitalized with COVID-19Observational Study Published on 2022-09-012022-10-05 Journal: Sleep & breathing = Schlaf & Atmung [Category] 임상, [키워드] 95%CI addition age analyses association BMI Body cardiovascular disease clinical Clinical outcome cohort study collected Complete coronavirus COVID-19 COVID-19 disease COVID-19 infection COVID-19 patient diabetes diagnosed with COVID-19 disease Gender group hospital Hospital stay Impact incidence increased mortality increased risk independent index investigated Lung disease male mass mechanism medical record Mortality Non-COVID-19 not differ Obstructive obstructive sleep apnea OSA Patient patients hospitalized patients with COVID-19 Presence Prevalence risk factor suggested was increased with COVID-19 [DOI] 10.1007/s11325-021-02476-z PMC 바로가기 [Article Type] Observational Study
Self-administered, remote assessment of SARS-CoV-2 seroprevalence in health care workersArticle Published on 2022-09-012022-11-15 Journal: The American journal of the medical sciences [Category] SARS, 진단, [키워드] clinician Cohort Community conducted Control enrolled Estimated Evidence Health care worker health care workers identify IgG immunoassay Infection infection rate lateral flow not differ Nurse point-of-care reported SARS-COV-2 infection SARS-CoV-2 nucleocapsid SARS-CoV-2 seroprevalence serologic testing seropositive subject the epidemic was performed widespread [DOI] 10.1016/j.amjms.2022.01.025 PMC 바로가기
Rapid Deployment of a Mobile Medical Clinic During the COVID-19 Pandemic: Assessment of Dyadic Maternal-Child CareObservational Study Published on 2022-09-012022-10-05 Journal: Maternal and child health journal [Category] 임상, [키워드] addressed analyses analyzed Anxiety assessment black Care clinic conducted COVID-19 COVID-19 pandemic demographic characteristics diagnosed dyadic Dyadic care English feasibility food insecurity hypertension Intervention Latino long-lasting Major Mobile Mobile medical clinic not differ participant Patient perceived benefit Perceived benefits Perception Postpartum care Postpartum care. provided Qualitative Rapid reported Spanish women [DOI] 10.1007/s10995-022-03483-6 PMC 바로가기 [Article Type] Observational Study