proteomics – Page 22 – Communicable Diseases Research

Proteomic landscape of SARS-CoV-2– and MERS-CoV–infected primary human renal epithelial cells

Research Article

Published on 2022-02-022022-10-30
Journal: Life Science Alliance [Category] COVID-19, COVID19(2023년), MERS, SARS,

Immune response pattern across the asymptomatic, symptomatic and convalescent periods of COVID-19

COVID-19의 무증상, 증상 및 회복기에 걸친 면역 반응 패턴

Article

Published on 2022-02-012022-09-11
Journal: Biochimica et biophysica acta. Proteins and proteo [Category] COVID19(2023년), SARS, 유전자 메커니즘,

A knowledge graph to interpret clinical proteomics data

Research

Published on 2022-01-312022-10-05
Journal: Nature biotechnology [Category] 바이오마커, 신약개발, 진단,

[키워드] accelerate Analysis Biomarker clinical clinically database flexible help Implementing Interpretation knowledge Knowledge graph machine learning algorithm platform Precision proteomics proteomics data provide Spread statistical
[DOI] 10.1038/s41587-021-01145-6 [Article Type] Research

Proteomic identification of the contents of small extracellular vesicles from in vivo Plasmodium yoelii infection

article

Published on 2022-01-312024-09-01
Journal: International Journal for Parasitology [Category] 말라리아,

[키워드] Exosomes Extracellular vesicles immunomodulation malaria Plasmodium proteomics
[Article Type] article

SARS-CoV-2 Infection Triggers Auto-Immune Response in ARDS

ARDS에서 SARS-CoV-2 감염 유발 자가면역 반응

Immunology

Published on 2022-01-282022-09-12
Journal: Frontiers in Immunology [Category] 진단,

Immuno-proteomic profiling reveals aberrant immune cell regulation in the airways of individuals with ongoing post-COVID-19 respiratory disease

Research article

Published on 2022-01-262022-10-05
Journal: Immunity [Category] SARS, 바이오마커,

[키워드] abnormality Activation acute COVID-19 airway airways Apoptosis B cell cause cell death Concentration COVID-19 Cytotoxic T cells dysfunction elevated epithelial Evidence Follow-up greater healthy control healthy individuals hospital discharge immune Immune cell Increased indicated individual Injury Long COVID lung abnormalities Lung disease lymphocyte monocyte Patient patients hospitalized Peripheral blood plasma post-COVID-19 patient Protein proteomes proteomics Regulation resolved Respiratory disease respiratory symptom respiratory tract respiratory viral infection reveal SARS-CoV-2 subset T cells tissue repair tissue-resident memory widespread
[DOI] 10.1016/j.immuni.2022.01.017 [Article Type] Research article

Identification of Robust Protein Associations With COVID-19 Disease Based on Five Clinical Studies

5개의 임상 연구를 기반으로 한 COVID-19 질병과의 강력한 단백질 연관성 식별

Immunology

Published on 2022-01-252022-09-11
Journal: Frontiers in Immunology [Category] 바이오마커, 유전자 메커니즘,

[키워드] Analysis Arthritis associations Blood cardiovascular CCL16 CCL2 CCL7 CCL8 CD274 circulating clinical condition conditions controls COVID-19 COVID-19 cytokine storm COVID-19 disease COVID-19 patient COVID-19 patients criteria CXCL10 CXCL11 cytokine Cytokine storm syndrome differentially expressed FIVE identification identify IFNγ IL18 IL18R1 IL1RN IL6 inflammation and cardiovascular markers Interaction investigated LGALS9 marker MERTK Multiple Multiple studies Olink proteomics overexpressed pathway Pathway analysis Pathways platform potential therapeutic targets profile Protein protein expression proteomics recruited replicate rheumatoid arthritis robust Shear stress Signaling specific protein Stress study inclusion Support syndrome the disease unique utility
[DOI] 10.3389/fimmu.2021.781100 PMC 바로가기 [Article Type] Immunology

Antigen Discovery in Circulating Extracellular Vesicles From Plasmodium vivax Patients

플라스모디움 비박스 환자의 순환 외부 소포에서 항원 발견

Original Research

Published on 2022-01-242024-08-08
Journal: Frontiers in Cellular and Infection Microbiology [Category] 말라리아,

[키워드] antigen discovery direct immuno-affinity capture Extracellular vesicles Plasmodium vivax proteomics
[DOI] 10.3389/fcimb.2021.811390 PMC 바로가기 [Article Type] Original Research

Looking at COVID-19 from a Systems Biology Perspective

시스템 생물학 관점에서 코로나19를 바라보다

Review

Published on 2022-01-222022-09-11
Journal: Biomolecules [Category] 신약개발,

Overexpression of the SARS-CoV-2 receptor angiotensin converting enzyme 2 in cardiomyocytes of failing hearts

Article

Published on 2022-01-192022-10-04
Journal: Scientific Reports [Category] 바이오마커,

[키워드] ACE2 ACE2 expression ACE2 receptor Biochemistry Biomarkers Biotechnology Cardiology cardiovascular comorbidity Cell Biology dependent on disease Diseases Donor Endothelial cell endothelial cells enzyme expressed expression fibroblast fibroblasts healthy donor heart heart failure hearts immunohistochemistry immunology in both groups infect cells Medical research Molecular biology Molecular medicine myocarditis organ outcome Patient Physiology proteomics Quantitative receptor risk RT-qPCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus subpopulation the SARS-CoV-2 tissue ventricular was measured was used
[DOI] 10.1038/s41598-022-04956-y PMC 바로가기 [Article Type] Article