SARS-CoV-2 strain
[용어속성] Virus
Inhibition of PIKfyve kinase prevents infection by Zaire ebolavirus and SARS-CoV-2
530
[키워드] 2019-nCoV/USA-WA1/2020
acute respiratory syndrome
Antiviral
antiviral drugs
apilimod
cathepsin
Cell
cell entry
chimeric
coronavirus
COVID-19
cytosol
distension
elicited
endosomal
Endosomes
envelope protein
Filovirus
form
functional
fusion protein
highest
Host
host cell
Infection
inhibit
inhibition
inhibitor
inhibitory compound
inhibitory effect
initiate
mechanism
membrane fusion
pathogen
pathway
Prevent
Probability
Protein
Proteolytic processing
Replication
SARS Coronavirus
SARS-CoV-2
SARS-CoV-2 strain
shown
Significance
subcellular
target
Vacuolin-1
vesicular stomatitis virus
viral infection
viral pathogen
virus
VSV
Zaire ebolavirus
ZEBOV
[DOI] 10.1073/pnas.2007837117 PMC 바로가기 [Article Type] 530
[DOI] 10.1073/pnas.2007837117 PMC 바로가기 [Article Type] 530
Evolutionary and structural analyses of SARS-CoV-2 D614G spike protein mutation now documented worldwide
Article
[키워드] Analysis
applied
association
bioinformatics
caused
clade
Clinical outcome
coronavirus 2
COVID-19 case
COVID-19 pandemic
D614G
deaths
diagnosed
disease severity
Epidemiology
Europe
Evolution
Evolutionary genetics
Future
genomic
human ACE2 receptor
Infectious diseases
Interaction
Johns Hopkins
lack
Metadata
Microbial genetics
Missense mutation
MONITOR
Mutation
Neutral
pandemic
performed
phenotype
Phylogenetic analysis
predominant
prevented
Protein
respiratory
SARS-CoV-2
SARS-CoV-2 D614G
SARS-CoV-2 genome
SARS-CoV-2 strain
sequenced
Spike protein
the spike protein
viral clade
virulence
virus
World Health Organization
[DOI] 10.1038/s41598-020-70827-z PMC 바로가기 [Article Type] Article
[DOI] 10.1038/s41598-020-70827-z PMC 바로가기 [Article Type] Article
Genome-wide analysis of SARS-CoV-2 virus strains circulating worldwide implicates heterogeneity
Article
[키워드] ACE2
acute respiratory syndrome
Amino acid
Analysis
analyzed
angiotensin-converting enzyme 2
annotation
arginine
Asia
Belgium
Case fatality rate
circulating
coding sequence
Complete
Computational biology and bioinformatics
conserved
Coronavirus-2
COVID-19 pandemic
Deletion
domain
effective
England
epidemiological data
epitope
Europe
European
Evolution
Frame
France
Frequency
genetic variants
genetics
Genome
genome sequence
genomic
GISAID database
globe
heterogeneous
implication
Interaction
Italy
lysine
Microbiology
Mutation
Netherlands
neutralizing antibody
North America
nucleotide
ORF10
ORF1ab
ORF7a
pandemic
polyprotein
Prophylaxis
Protein
Proteins
RBD
remained
reported
residue
responsible
RNA virus
SARS-CoV-2
SARS-COV-2 infection
SARS-CoV-2 strain
SARS-CoV-2 virus strain
sequence
Shanghai
Spain
Substitution
the SARS-CoV-2 genome
Variation
Viral protein
virus strains
[DOI] 10.1038/s41598-020-70812-6 PMC 바로가기 [Article Type] Article
[DOI] 10.1038/s41598-020-70812-6 PMC 바로가기 [Article Type] Article
Anti-COVID-19 multi-epitope vaccine designs employing global viral genome sequences
Bioinformatics
[키워드] alleles
Analysis
antigenic
antigenicity
approach
approved
B cell epitope
binding
binding affinity
caused
Complete
consensus sequence
coronavirus SARS-CoV-2
COVID-19
CTL epitope
demonstrated
develop
epitope
epitope mapping
Escherichia coli
expression
Genome
GISAID
global pandemic
global public health
HLA
HTL
immune response
Immunity
immunogenic potential
immunoinformatics
in silico
interferon
molecular docking
Multi-epitope vaccine
NC_045512.2
non-allergenic
ORFs
overlapping
Phylogeny
predicted
reading
reference genome
reference sequence
reported
Result
retrieved
SARS-CoV-2
SARS-CoV-2 strain
screened
significantly
the Coronaviridae
TLR8
Treatment
Vaccine
viral genome sequence
viral strains
was performed
[DOI] 10.7717/peerj.9541 PMC 바로가기 [Article Type] Bioinformatics
[DOI] 10.7717/peerj.9541 PMC 바로가기 [Article Type] Bioinformatics
Comparative Genomic Analysis of Rapidly Evolving SARS-CoV-2 Reveals Mosaic Pattern of Phylogeographical Distribution
Research Article
[키워드] acute respiratory syndrome
addition
Affect
age factor
Amino acid
Analysis
analyzed
binding
caused
circulating
claimed
Comparative
Complete
coronavirus
coronavirus disease
COVID-19
COVID-19 pandemic
COVID-19 patients
COVID-2019
evade
Frame
GenBank accession
Genome
genomic
geographical region
global pandemic
Health
health condition
Host
Human
human receptors
IL-8
impacted
IMPROVE
Infection
interact
Interaction
interferon
involved
less
methyltransferase
mosaic
mRNA
mutant
mutant proteins
NKRF
nonsynonymous mutation
novel SARS-CoV-2 virus
nsp13
nsp14
Nsp15
ORF1b
outbreak
pattern
Pneumonia
polyproteins
Population
Protein
Replication
replicative
required
residue
RNA
S-protein
SARS-CoV-2
SARS-CoV-2 genome
SARS-CoV-2 strain
severity
signaling pathway
Single nucleotide polymorphism
SNPs
Spread
stability
Structural analysis
the disease
the interferon
the United State
The United States
Transmission
transmission rates
Travel
unique
viral isolate
Viral protein
viral replication
viral variant
virus
viruses
wild-type
Wuhan, China
[DOI] 10.1128/mSystems.00505-20 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1128/mSystems.00505-20 PMC 바로가기 [Article Type] Research Article
Discovery and Genomic Characterization of a 382-Nucleotide Deletion in ORF7b and ORF8 during the Early Evolution of SARS-CoV-2
Research Article
[키워드] acute respiratory syndrome
addition
Antibody Response
assist
characterization
circulating
coronavirus
country
COVID-19
Deletion
deletion variant
deletions
described
eliminating
epidemiological
Evidence
Frame
genetic change
Genome
Host
hosts
Human
humans
Hypothesis
immune evasion
immune response
in vitro
lack
natural selection
no difference
ORF7b
ORF8
Patient
Phylogeny
predominant
reduced
replicative fitness
retained
robust
SARS-CoV
SARS-CoV-2
SARS-COV-2 infection
SARS-CoV-2 strain
screened
significantly higher
Singapore
Spain
sustained
Taiwan
the SARS epidemic
the SARS-CoV-2
Transcription
transcription regulatory sequence
transmission of SARS-CoV-2
TRS
Vaccination strategies
Vaccines
Viral load
virus
virus attenuation
wild type
[DOI] 10.1128/mBio.01610-20 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1128/mBio.01610-20 PMC 바로가기 [Article Type] Research Article
Understanding genomic diversity, pan-genome, and evolution of SARS-CoV-2
Bioinformatics
[키워드] Analysis
analyzed
ancestor
bat
bioinformatics
contributed
coronavirus
CoV
COVID-19
Diagnosis
disease
Epidemiology
Evolution
Evolution of SARS-CoV-2
Genome
genome organization
genomic
Genomics
genus Betacoronavirus
help
homology
hosts
indicate
Infection
isolate
isolates
majority
medium
mutational hotspot
mutations
novel virus
pandemic
pangolin
pathogenicity
Phylogeny
predicted
Probability
respiratory
SARS
SARS-CoV
SARS-CoV-2
SARS-CoV-2 strain
SARS-CoV-2 strains
sequenced
the SARS-CoV-2 genome
Treatment
understanding
unique
viral disease
Wuhan, China
[DOI] 10.7717/peerj.9576 PMC 바로가기 [Article Type] Bioinformatics
[DOI] 10.7717/peerj.9576 PMC 바로가기 [Article Type] Bioinformatics
SARS-CoV-2 genomic surveillance in Taiwan revealed novel ORF8-deletion mutant and clade possibly associated with infections in Middle East
Research Article
[키워드] acute respiratory syndrome
addition
Americas
clade
clades
contributed
coronavirus
COVID-19
Culture
dominant
Europe
First wave
Frame
Genome sequencing
Genomic surveillance
genomic variation
Infection
Iran
Local
Middle East
mutant
Mutation
ORF8
ORF8 deletion
Patient
performed
Phylogenetic analysis
Phylogeny
SARS-CoV-2
SARS-CoV-2 genomic surveillance
SARS-CoV-2 strain
SARS-CoV-2 transmission
second wave
sequenced
Sequencing
strain
Strains
Taiwan
trajectory
Transmission
Travel
Turkey
virus
Wuhan
[DOI] 10.1080/22221751.2020.1782271 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1080/22221751.2020.1782271 PMC 바로가기 [Article Type] Research Article
Primary exposure to SARS-CoV-2 protects against reinfection in rhesus macaques
Report
[키워드] acute respiratory syndrome
caused
cellular immunity
changes
characterized
clinical manifestation
coronavirus
Coronavirus disease 2019
COVID-19
detectable
dissemination
early recovery
gastrointestinal tracts
global pandemic
histopathological
humoral
immune responses
Infection
initial
interstitial pneumonia
neutralizing antibody
Patient
Primary infection
PROTECT
Reinfection
rhesus
rhesus macaque
rhesus macaques
risk
SARS-CoV-2
SARS-COV-2 infection
SARS-CoV-2 strain
subsequent
viral disease
[DOI] 10.1126/science.abc5343 PMC 바로가기 [Article Type] Report
[DOI] 10.1126/science.abc5343 PMC 바로가기 [Article Type] Report