Clinical and genomic data of sars-cov-2 detected in maternal-fetal interface during the first wave of infection in Brazil브라질의 첫 번째 감염 파동 동안 산모-태아 경계면에서 검출된 sars-cov-2의 임상 및 게놈 데이터Article Published on 2022-06-012022-09-11 Journal: Microbes and infection [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료기술, [키워드] abortion Americas Apoptosis B.1.1.28 B.1.1.33 Brazil circulating clinical Clinical virology contribute coronavirus fetal Fetal placenta First wave FIVE genomes genomic data gestation Ground-glass opacities ground-glass opacity highest hospital hospital discharge IgM Illumina Miseq in viral indicate induction of apoptosis Infection interferon involved Lineage Lungs Maternal Mild molecular virology mother Mutation Neonatal infection Newborn nonsynonymous mutation Nonsynonymous mutations Nsp12 Nsp3 ORF3 ORF7b outcome Pathways Phylogeny Placenta pregnant women Preterm birth preterm births Protein qPCR Replication reported RT-qPCR SARS-CoV-2 SARS-COV-2 infection secretion Sequencing South spontaneous abortion state stillborn symptomatic symptomatic cases tested treated umbilical Umbilical cord vertical transmission viral replication Virological virus women [DOI] 10.1016/j.micinf.2022.104949 PMC 바로가기 [Article Type] Article
A novel case of lupus nephritis and mixed connective tissue disorder in a COVID-19 patientCase report Published on 2022-06-012022-10-05 Journal: Annals of Medicine and Surgery [Category] 진단, [키워드] acute renal injury addition addressed Administered Anemia antinuclear antibody Autoimmune Autoimmune disease autoimmune disorder Autoimmune disorders characterized complete blood count connective tissue COVID-19 COVID-19 infection COVID-19 patient creatinine Critical Cyclophosphamide diagnosed diagnostic discharged disease disorder edema elevated Factor female hepatosplenomegaly Hydroxychloroquine Inflammatory marker intravenous lower dose Lupus lupus nephritis medication morbidity nodules nuclear oral steroid organ dysfunction pathophysiological mechanism Patient PCR-confirmed COVID-19 Pneumonia polymyositis positive Prevent Protein reported respiratory infection Rheumatoid ribonucleoprotein Scleroderma SLE steroid striae symptomatic systemic treat Treatment [DOI] 10.1016/j.amsu.2022.103653 [Article Type] Case report
Assessment of the optic nerve, macular, and retinal vascular effects of COVID-19Research article Published on 2022-06-012022-10-05 Journal: Canadian journal of ophthalmology. Journal canadie [Category] 바이오마커, 진단, [키워드] abnormality Analysis assessment Asymptomatic COVID-19 average Biomarker complex conducted control group COVID-19 COVID-19 group COVID-19 symptom cross-sectional Diagnostic method domain evaluate the effect Foveal avascular zone ganglion cell healthy control infection with SARS-CoV-2 neurologic Neurovascular objective Optical coherence tomography participant Patient peripapillary quantified recovering from COVID-19 Region Result retinopathy SARS-COV-2 infection significantly structures subject symptomatic symptoms of COVID-19 Vascular vascular effect vessel were measured [DOI] 10.1016/j.jcjo.2022.06.016 [Article Type] Research article
Clinical characterization of COVID-19 breakthrough infections, PhilippinesCOVID-19 돌발 감염의 임상 특성, 필리핀Article Published on 2022-06-012022-09-11 Journal: Journal of Clinical Virology [Category] COVID19(2023년), SARS, 치료기술, [키워드] administration Alpha Asymptomatic Beta booster dose Breakthrough infection breakthrough infections characterized clinical clinically CoronaVac COVID-19 Ct values Delta VOC Evidence HCW HCWs healthcare worker Healthcare workers Inactivated vaccine majority male PCR Philippines risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 transmission sequenced severe cases significantly lower symptomatic viral loads VOCs [DOI] 10.1016/j.jcv.2022.105157 PMC 바로가기 [Article Type] Article
Durability of Protection Against Symptomatic COVID-19 Among Participants of the mRNA-1273 SARS-CoV-2 Vaccine TrialmRNA-1273 SARS-CoV-2 백신 시험 참가자의 코로나19 증상에 대한 보호 지속성Article Published on 2022-06-012022-09-11 Journal: JAMA Network Open [Category] 임상, [키워드] Against cohort study COVID-19 Moderna mRNA mRNA-1273 participant protection SARS-CoV-2 symptomatic symptomatic COVID-19 vaccine trial [DOI] 10.1001/jamanetworkopen.2022.15984 PMC 바로가기 [Article Type] Article
Effect of disease-modifying treatments on antibody-mediated response to anti-COVID19 vaccination in people with multiple sclerosis다발성 경화증 환자의 항-COVID19 백신 접종에 대한 항체 매개 반응에 대한 질병 조절 치료의 효과Article Published on 2022-06-012022-09-11 Journal: Journal of Neurology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] Adverse adverse event adverse events age aligned analysed anti-CD20 Anti-CD20 antibodies Anti-CD20 antibody anti-CD20 treatment Anti-spike antibody Antibody Response CD19 CD19+ CD20 CD20 deplething therapies cell count cell-mediated immune cell-mediated immune response Cohort correlated COVID-19 COVID-19 infection COVID-19 infections COVID-19 vaccines depleting detectable diagnosed Disease-modifying therapies Effect elicited event female fingolimod Follow-up Frequency IgG antibody immune response investigation material median median age Multiple multiple sclerosis non-responders Patient proportion protective immune response Protein receiving recorded Responder responders symptomatic therapy titre treated Treatment vaccination Vaccine was reduced [DOI] 10.1007/s00415-022-11003-3 PMC 바로가기 [Article Type] Article
Nitric oxide boosters as defensive agents against COVID-19 infection: an opinionCOVID-19 감염에 대한 방어제로서의 산화질소 부스터: 의견Article Published on 2022-06-012022-09-11 Journal: Journal of biomolecular structure & dynamics [Category] COVID19(2023년), SARS, 치료제, [키워드] agent Antiviral compound booster co-morbidity Compound COVID-19 death disease food highest human body immune system Immunity introduced literature nitric oxide NO NO-release pandemic disease Patient Scientific community severity Support symptomatic synthetic moieties. the patient Vaccine viral infection [DOI] 10.1080/07391102.2020.1852969 PMC 바로가기 [Article Type] Article
Silent hypoxia is not an identifiable characteristic in patients with COVID-19 infectionObservational Study Published on 2022-06-012022-10-05 Journal: Respiratory medicine [Category] COVID19(2023년), SARS, 임상, [키워드] acute respiratory distress adjusted age ARDS Asymptomatic cause characteristic clinical Clinical deterioration Cohort COVID-19 COVID-19 cohort died East Effect hospital hypoxaemia hypoxaemic respiratory failure hypoxia ICU ICU admission Infection linear Mortality Observational cohort study Patient patients patients with COVID-19 performed phenotype physiological positive required responses ROX index SARS-CoV-2 SARS-COV-2 infection symptomatic syndrome tested Trust Variability with COVID-19 [DOI] 10.1016/j.rmed.2022.106858 PMC 바로가기 [Article Type] Observational Study
Marginal BH4 deficiencies, iNOS, and self-perpetuating oxidative stress in post-acute sequelae of Covid-19Research article Published on 2022-06-012022-10-05 Journal: Medical Hypotheses [Category] 변종, 유전자 메커니즘, [키워드] AGMO approach Clinical treatment deficiencies deficiency exhibited Ferroptosis GCH1 GCH1 mutations GTP heterozygous homozygous mutation hyperinflammatory state impair Inflammatory initial innate immune system involved less manuscript Marginal Marginally deficient BH4 metabolic processe Mutation nitric oxide organ systems organs oxidative stress Oxide PASC Post-acute sequelae of COVID-19 (PASC) resulting SARS-CoV-2 symptomatic Synthase tetrahydrobiopterin the patient Treatment Uncoupling iNOS [DOI] 10.1016/j.mehy.2022.110842 [Article Type] Research article
Are Dyskeratosis Congenita patients at higher risk of symptomatic COVID-19?Correspondence Published on 2022-06-012022-10-05 Journal: Medical Hypotheses [Category] 유전자 메커니즘, [키워드] association BMFBone Marrow Failure bone marrow failure clinical care complex Coronavirus disease 2019 COVID-19 COVID-19coronavirus disease 2019 DCDyskeratosis Congenita disease disorder Dyskeratosis Congenita heterogeneous higher risk increase indicated leukocyte mortality rate mutated Patient RNA severe symptom stem cells symptomatic telomerase Telomere Length TLTelomere Length transcriptase [DOI] 10.1016/j.mehy.2022.110843 [Article Type] Correspondence