Virologic Efficacy of Casirivimab and Imdevimab COVID-19 Antibody Combination in Outpatients With SARS-CoV-2 Infection: A Phase 2 Dose-Ranging Randomized Clinical TrialSARS-CoV-2 감염 외래 환자에서 Casirivimab과 Imdevimab COVID-19 항체 조합의 바이러스학적 효능: 2상 용량 범위 무작위 임상 시험Clinical Trial Published on 2022-08-012022-09-12 Journal: JAMA Network Open [Category] SARS, 임상, 진단, [키워드] 95% CI Administered age Asymptomatic average baseline Casirivimab clinical collected COVID-19 death dose double-blind Efficacy efficacy analysis greater Hispanic Hospitalization hypersensitivity reactions Imdevimab in viral intravenous mean difference monoclonal antibody combination outcome Outpatient parallel-group participant Participants Patient patients Phase 2 Phase 3 Placebo placebo-controlled primary end point Randomized randomized clinical trial ranged Reactions reduced reduction reported risk factor SARS-CoV-2 SARS-COV-2 infection Serious Adverse Event seronegative severe COVID-19 study drug Subcutaneous symptomatic symptomatic patient The United States Treatment Viral load were excluded white [DOI] 10.1001/jamanetworkopen.2022.25411 PMC 바로가기 [Article Type] Clinical Trial
Detection of SARS-CoV-2 in exhaled air using non-invasive embedded strips in masks마스크에 비침습적 내장 스트립을 사용하여 호기에서 SARS-CoV-2 감지Article Published on 2022-08-012022-09-11 Journal: American journal of infection control [Category] SARS, 치료기술, [키워드] alcohol approach asymptomatic individual Asymptomatic individuals comparable conditions COVID-19 detect detection Detection limit face Face masks feasibility Frequently Health individual individuals infected individuals Infection Infectious virus invasive Mask Masks nasal swab Non-invasive not correlated pandemic Personal protective equipment platform polyvinyl alcohol Protective qRT-PCR qRT-PCR analysis Quantitative RT-qPCR SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 RNA secretion symptom status symptomatic individual tested Viral load viral loads Viral RNA virus vRNA Xerostomia [DOI] 10.1016/j.ajic.2022.01.010 PMC 바로가기 [Article Type] Article
Remdesivir reduced upper respiratory tract SARS-CoV-2 viral RNA concentration in COVID-19 patients who developed pneumonitisCorrespondence Published on 2022-08-012022-10-05 Journal: The Journal of Infection [Category] COVID19(2023년), SARS, 치료제, [키워드] Anti-viral clinical Concentration COVID-19 COVID-19 patient reduced Remdesivir SARS-CoV-2 SARS-CoV-2 viral RNA Treatment upper respiratory tract viral kinetics Viral load Virological [DOI] 10.1016/j.jinf.2022.08.031 [Article Type] Correspondence
A colorimetric electronic tongue for point-of-care detection of COVID-19 using salivary metabolitesResearch article Published on 2022-08-012022-10-05 Journal: Talanta [Category] 치료기술, [키워드] Accuracy can be used category change colorimetric detection complexes Concentration COVID-19 COVID-19 patients cured detect diabete diagnose Donor Efficiency Evidence healthy healthy individuals identify individuals Kidney disease marker metabolite metabolomics Paper-based device participant Patient point-of-care receptor recorded rRT-PCR Saliva salivary Sensor array smoker tongue unique Viral load [DOI] 10.1016/j.talanta.2022.123537 [Article Type] Research article
SARS-COV-2 viral load in tears of patients with COVID-19 in the early symptomatic stages: comparison of two different tear sampling methodsArticle Published on 2022-08-012023-06-19 Journal: International ophthalmology [Category] COVID19(2023년), MERS, SARS, [키워드] COVID-19 SARS-CoV-2 tears Viral load [DOI] 10.1007/s10792-022-02243-3 PMC 바로가기
Recombinant chimpanzee adenovirus vector vaccine expressing the spike protein provides effective and lasting protection against SARS-CoV-2 infection in mice스파이크 단백질을 발현하는 재조합 침팬지 아데노바이러스 벡터 백신은 생쥐에서 SARS-CoV-2 감염에 대해 효과적이고 지속적인 보호를 제공합니다Article Published on 2022-08-012022-09-11 Journal: Virologica Sinica [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] Adenovirus Cellular immune response Chimpanzee Chimpanzee adenovirus vector clinical evaluation death dose dropped effective Effectiveness Efficacy expected expressing full-length global public health histological abnormalities histological abnormality histopathological examination humoral Humoral and cellular immune responses immune responses immunization immunized mice Infection Long-term protection lung Lungs mice Mild Neutralizing antibodies neutralizing antibody pandemic provide Rapid recombinant recombinant chimpanzee adenovirus SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pandemic short term the SARS-CoV-2 the spike protein vaccination Vaccine variants of concern vectored vaccine Viral Viral load widespread [DOI] 10.1016/j.virs.2022.05.006 PMC 바로가기 [Article Type] Article
Sensitivity of severe acute respiratory syndrome coronavirus type 2 rapid antigen point-of-care tests in vaccinated patients백신 접종 환자에서 중증급성호흡기증후군 코로나바이러스 2형 신속항원 현장진단 검사 민감도Article Published on 2022-08-012022-09-11 Journal: European journal of emergency medicine : official [Category] COVID19(2023년), SARS, 치료기술, [키워드] 95% CI 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus age Antigen Antigen point-of-care test asymptomatic patients calculated confidence interval coronavirus COVID-19 infections detect evaluate evaluated inclusion criteria Patient patients performed POC test POC test result POC tests positive public health Rapid recorded reverse transcription PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 positive patient SARS-CoV-2 positive patients security sensitivities sensitivity significantly symptomatic symptomatic and asymptomatic symptomatic and asymptomatic patients symptomatic patient Symptomatic patients test result tested Viral load [DOI] 10.1097/MEJ.0000000000000928 PMC 바로가기 [Article Type] Article
Pathways to community transmission of COVID–19 due to rapid evaporation of respiratory viruletsResearch article Published on 2022-08-012022-10-05 Journal: Journal of Colloid and Interface Science [Category] 변종, [키워드] Analysis community transmission cough COVID–19 dimension droplet transmission Evaporation facilitate feature globe pandemic ranged Respiratory droplets Result Simulation sneeze temperature trajectory Transmission Viral load virus [DOI] 10.1016/j.jcis.2022.03.098 [Article Type] Research article
Cycle threshold responses in SARS-COV2 PCR tests depend on the method by which the samples were obtained and require strict global standardizationSARS-COV2 PCR 테스트의 주기 임계값 응답은 샘플을 얻은 방법에 따라 다르며 엄격한 글로벌 표준화가 필요합니다.Article Published on 2022-08-012022-09-11 Journal: Infection [Category] COVID19(2023년), SARS, 치료기술, [키워드] Analysis CDC Ct values cycle cycle threshold detect determine emergency room Epidemic false negatives hospitals include PCR PCR test penetration platform reduce response risk SARS-CoV2 Schools Standardization Swab threshold Viral load virus [DOI] 10.1007/s15010-022-01772-4 PMC 바로가기 [Article Type] Article
SARS-CoV-2 accelerated clearance using a novel nitric oxide nasal spray (NONS) treatment: A randomized trialArticle Published on 2022-08-012022-10-06 Journal: Lancet Reg Health Southeast Asia [Category] 진단, [키워드] 1:1 95% CI accelerate accelerated age Anti-viral treatment assessment baseline clearance clinical trial Comorbidities comparable Concentration COVID-19 COVID-19 illness defined demonstrated double-blind Endpoint evaluated funding greater greater transmissibility high risk individuals infected with SARS-CoV-2 Laboratory Limited median Mild multicentre mutate nasal Nasal spray nasal swab nitric oxide nostril parallel group Patient pharmaceutical Placebo placebo-controlled polymerase chain primary analysis population progression proportion provided Randomized randomized trial receiving reduce reverse transcription RT-PCR SARS-CoV-2 SARS-CoV-2 RNA secondary Seven study medication symptomatic the placebo group therapy Treatment treatment difference vaccination Viral load virus virus clearance virus RNA [DOI] 10.1016/j.lansea.2022.100036 PMC 바로가기 [Article Type] Article