Early predictive factors of progression from severe type to critical ill type in patients with Coronavirus Disease 2019: A retrospective cohort studyResearch Article Published on 2020-12-022022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] 95% CI Admission Clinical outcome collected correlation COVID-19 Creatine kinase-MB Critical diagnosed Diagnosis electronic medical record enrolled Factor global public health higher risk Hospital admission Hospital stay identify ill patient independent independent predictor lower risk Lymphocyte count mortality rate multivariable logistic regression neutrophil count Odds ratio oxygen saturation Patient patients predict Predictive primary endpoint progressed progression pulse Result retrospective cohort study Severe case severe COVID-19 patients Tongji Hospital variables was used worldwide pandemic Wuhan, China [DOI] 10.1371/journal.pone.0243195 PMC 바로가기 [Article Type] Research Article
Projected supportive effects of Pycnogenol Ⓡ in patients suffering from multi-dimensional health impairments after a SARS-CoV2 infectionSARS-CoV2 감염 후 다차원적 건강 장애로 고통받는 환자에서 피크노제놀Ⓡ의 지지 효과 예상Review Published on 2020-12-012022-08-31 Journal: International journal of antimicrobial agents [Category] MERS, SARS, 치료제, [키워드] affecting Anti-inflammatory Clinical studies Coagulopathies consequence Corona Corona virus COVID-19 COVID-19 patients demonstrated Effect endothelial cells Endothelial dysfunction Endotheliitis French Health health problems impairment Infection Inflammation initial leads maritime microvascular injury multiple organs Patient pine Pine bark extract problem Pycnogenol(Ⓡ) recent respiratory Respiratory system resulting SARS viruses SARS-CoV2 SARS-CoV2 infection Severe acute respiratory syndrome Severe Acute Respiratory Syndrome Corona Virus Symptom triggered Vascular Virus Disease were infected worldwide pandemic [DOI] 10.1016/j.ijantimicag.2020.106191 PMC 바로가기 [Article Type] Review
A biomarker based severity progression indicator for COVID-19: the Kuwait prognosis indicator scoreCOVID-19에 대한 바이오마커 기반 중증도 진행 지표: 쿠웨이트 예후 지표 점수Article Published on 2020-12-012022-08-31 Journal: Biomarkers : biochemical indicators of exposure, r [Category] MERS, SARS, 바이오마커, [키워드] acute respiratory distress acute respiratory distress syndrome adverse outcome age albumin Biomarker calculated calculator calibration Clinical course collected consecutive patient Course COVID-19 COVID-19 disease criterion CRP dataset death defined demonstrated Diagnosis disease severity Final Health Health policy Hospital admission Inclusion independent predictor independent predictors Infection Kuwait logit lymphocyte Mild monocyte Mortality Most patients Patient PCR percentage Pneumonia predict primary endpoint procalcitonin Prognosis prognostic model progression recruited resources respiratory distress risk serum albumin severe COVID-19 severe COVID-19 disease severity syndrome the disease variable with COVID-19 worldwide pandemic Wuhan Wuhan, China [DOI] 10.1080/1354750X.2020.1841296 PMC 바로가기 [Article Type] Article
FDA efficiency for approval process of COVID-19 therapeuticsReview Published on 2020-12-012022-10-30 Journal: Infectious Agents and Cancer [Category] COVID-19, [키워드] approval Autoimmune diseases caused clinical clinical study Community complex coronavirus disease 19 COVID-19 COVID-19 therapeutics drug Drug development drugs Efficacy Efficiency Emergency use authorization EUA facilitate FDA FDA-approved drug food Health Hydroxychloroquine include IND Infection mechanism pandemic pathway potential therapies Prophylactic Regulatory regulatory agency Remdesivir respiratory SARS-CoV-2 Spread the United State therapeutic Therapeutic treatment to define Toxicity Treatment USA worldwide pandemic [DOI] 10.1186/s13027-020-00338-z PMC 바로가기 [Article Type] Review
Molecular diagnosis for the novel coronavirus SARS-CoV-2: lessons learnt from the Ghana experience신종 코로나바이러스 SARS-CoV-2에 대한 분자 진단: 가나 경험에서 배운 교훈Special Article Published on 2020-12-012022-09-12 Journal: Ghana Medical Journal [Category] MERS, SARS, 진단, [키워드] “pooling” 48 hour adopted chain Community Contact tracing contributed country Department diagnose Diagnosis effective response Epidemics equipment foundation funding Ghana GHS had no increase in Infection Jack Ma Laboratory manuscript Memorial Ministry of Health mitigate molecular Molecular diagnosis NIC Novel coronavirus number of sample Other overcome Pandemics peaking processed provide provided reaction reagent reduced reported Research rRT-PCR Sample SARS-CoV-2 SARS-COV-2 infection sensitivity service Spread submission supported test result Testing the SARS-CoV-2 unit university Virology virus were recorded World Health Organization worldwide pandemic [DOI] 10.4314/gmj.v54i4s.12 PMC 바로가기 [Article Type] Special Article
Pervasive generation of non-canonical subgenomic RNAs by SARS-CoV-2SARS-CoV-2에 의한 비정규 서브게놈 RNA의 광범위한 생성Research Published on 2020-12-012022-08-13 Journal: Genome Medicine [Category] MERS, SARS, 유전자 메커니즘, [키워드] 3′ end 5′ UTR abundance accessory protein addition Analysis approaches canonical canonical sgRNA canonical sgRNAs caused Cell culture condition Consistency Coordinate coronavirus disease Coronavirus disease 2019 Coverage COVID-19 determine Direct RNA sequencing eight Evidence family Coronaviridae FIVE generate Genome highlight homology Host identify in viral increase in independent Infection information Integrative analysis junction landscape leader sequence make up nc-sgRNA nc-sgRNAs non-canonical sgRNA non-canonical sgRNAs non-canonical subgenomic RNA offer open reading frames ORF ORF1a ORFs positive-sense RNA virus Region reported Result RNA RNA virus SARS-CoV-2 SARS-CoV-2 biology SARS-CoV-2 genome SARS-CoV-2 pathogenesis SARS-CoV-2 RNA SARS-CoV-2 sgRNA SARS-CoV-2 sgRNAs SARS-CoV-2 transcriptome SARS-CoV-2 transcriptomes sequence sequences Sequencing Seven sgRNA sgRNAs subgenomic RNA subgenomic RNAs supplementary material the SARS-CoV-2 genome Transcription transcriptional activity transcriptional regulatory sequence transcriptional regulatory sequences transcriptomes TRS TRS-B TRS-L Viral viral isolate viral isolates viral RNAs was used worldwide pandemic [DOI] 10.1186/s13073-020-00802-w PMC 바로가기 [Article Type] Research
Clinical characteristics on admission predict in-hospital fatal outcome in patients aged ≥75 years with novel coronavirus disease (COVID-19): a retrospective cohort studyResearch Article Published on 2020-11-302022-10-27 Journal: BMC Geriatrics [Category] COVID-19, [키워드] 95% CI 95% confidence interval Admission age body temperature Characteristics clinical Clinical characteristics consecutive patient coronavirus disease COVID-19 patient creatinine critical cases D-dimer death died discharged elderly fatality female Fever Final Follow-up hospital hs-TNI identify In-hospital In-hospital death independent risk factor Laboratory lactic dehydrogenase LDH lymphocyte median age medical records N-terminal novel novel coronavirus disease NT-proBNP observation Odds ratio outcome oxygen saturation Patient peptide Platelet predict prediction reduced Result retrospective cohort study risk factor SARS-CoV-2 sensitivity Sex supplementary material troponin I worldwide pandemic [DOI] 10.1186/s12877-020-01921-0 PMC 바로가기 [Article Type] Research Article
Clinical characteristics on admission predict in-hospital fatal outcome in patients aged ≥75 years with novel coronavirus disease (COVID-19): a retrospective cohort studyResearch Article Published on 2020-11-302022-10-27 Journal: BMC Geriatrics [Category] Coronavirus, COVID-19, SARS, [키워드] 95% CI 95% confidence interval Admission age body temperature Characteristics clinical Clinical characteristics consecutive patient coronavirus disease COVID-19 patient creatinine critical cases D-dimer death died discharged elderly fatality female Fever Final Follow-up hospital hs-TNI identify In-hospital In-hospital death independent risk factor Laboratory lactic dehydrogenase LDH lymphocyte median age medical records N-terminal novel novel coronavirus disease NT-proBNP observation Odds ratio outcome oxygen saturation Patient peptide Platelet predict prediction reduced Result retrospective cohort study risk factor SARS-CoV-2 sensitivity Sex supplementary material troponin I worldwide pandemic [DOI] 10.1186/s12877-020-01921-0 PMC 바로가기 [Article Type] Research Article
Gastrointestinal Endoscopy in the Era of COVID-19Medicine Published on 2020-11-262022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] acute respiratory syndrome affected approach assumed caused change coronavirus coronavirus (2019-nCoV) Coronavirus disease 2019 Coronavirus-2 COVID-19 COVID-19 patient COVID-19 testing death decrease disease transmission Effect endoscopy Face masks fellowship and training gastroenterology Gastrointestinal gastrointestinal disease globe highlight lockdown mandatory Multiple National pandemic (COVID-19) pandemic progresse Patient care patients performed Personal protective equipment Precaution proportion reduction reduction in resulting risk Safe SARS-CoV-2 SARS-COV-2 infection shown the disease Transmission virus virus transmission Volume worldwide pandemic [DOI] 10.3389/fmed.2020.587602 PMC 바로가기 [Article Type] Medicine
Ventilation use in nonmedical settings during COVID-19: Cleaning protocol, maintenance, and recommendationsArticles Published on 2020-11-262022-10-29 Journal: Toxicology and Industrial Health [Category] COVID-19, [키워드] addition China cleaning Community Coronavirus disease 2019 COVID-19 Health hospitals Indoor air quality mechanical ventilation nonmedical pandemic Patient physical distancing protocol recommendation risk risk of transmission SARS-CoV-2 SARS-CoV-2 transmission Schools the disease the United State Treatment Ventilation worldwide pandemic [DOI] 10.1177/0748233720967528 PMC 바로가기 [Article Type] Articles