Network machine learning maps phytochemically rich “Hyperfoods” to fight COVID-19Primary Research Published on 2021-01-022022-10-04 Journal: Human Genomics [Category] MERS, 신약개발, [키워드] Accuracy Algorithm Analysis Antiviral antiviral properties approved drug calibrated candidate clinical study clinically common drug Compound coumarin COVID-19 database drug candidate drug repositioning food Gene-gene networks identify in silico indole ingredient interactomics Intervention machine machine learning Metabolic disorders network platform Precision predict predicted SARS-CoV-2 supplementary material turn Viral diseases was used [DOI] 10.1186/s40246-020-00297-x PMC 바로가기 [Article Type] Primary Research
Brief Report: Impact of COVID-19 on Individuals with ASD and Their Caregivers: A Perspective from the SPARK CohortBrief Report Published on 2021-01-022022-10-29 Journal: Journal of autism and developmental disorders [Category] Coronavirus, MERS, SARS, [키워드] age ASD autism Autism Spectrum Disorder benefit Caregiver Community coronavirus COVID-19 disorder distress enrolled FIVE Follow-up Impact implication individual lowest moderate pandemic participant receiving reported services Strategy Stress supplementary material Support Symptom telehealth the United State Therapies while worsening [DOI] 10.1007/s10803-020-04816-6 PMC 바로가기 [Article Type] Brief Report
Interstate disparities in the performances in combatting COVID-19 in India: efficiency estimates across statesResearch Article Published on 2020-12-292022-10-28 Journal: BMC Public Health [Category] COVID-19, MERS, SARS, [키워드] affected Analysis benefit contrary country COVID-19 COVID-19 pandemic Data analysis demonstrated determinant disease Effect Efficiency estimate facilitated Factor Health health system India Inefficiency effects investigated maintain management Novel coronavirus outcome Recovery rate responsible restrict Result Sex social distancing Spread Stochastic production frontier supplementary material the disease Variability variable variables were used [DOI] 10.1186/s12889-020-10051-6 PMC 바로가기 [Article Type] Research Article
The situation of elderly with cognitive impairment living at home during lockdown in the Corona-pandemic in GermanyResearch Article Published on 2020-12-292022-10-27 Journal: BMC Geriatrics [Category] COVID-19, [키워드] activity Analysis Anxiety anxiety and loneliness average Care clinics cognitive Cognitive impairment Corona Corona virus COVID-19 decrease Dementia Depression depressive symptom DSM-5 expected Frequency Germany Health Health care system knowledge lockdown loneliness majority measure outbreak pandemic participant Participants Practitioner Prevalence primary care Psychological reported Result Seven significantly social contact social distancing supplementary material Support Symptom talking therapy utilization variable were assessed worsened [DOI] 10.1186/s12877-020-01957-2 PMC 바로가기 [Article Type] Research Article
The situation of elderly with cognitive impairment living at home during lockdown in the Corona-pandemic in GermanyResearch Article Published on 2020-12-292022-10-27 Journal: BMC Geriatrics [Category] Coronavirus, COVID-19, MERS, SARS, [키워드] activity Analysis Anxiety anxiety and loneliness average Care clinics cognitive Cognitive impairment Corona Corona virus COVID-19 decrease Dementia Depression depressive symptom DSM-5 expected Frequency Germany Health Health care system knowledge lockdown loneliness majority measure outbreak pandemic participant Participants Practitioner Prevalence primary care Psychological reported Result Seven significantly social contact social distancing supplementary material Support Symptom talking therapy utilization variable were assessed worsened [DOI] 10.1186/s12877-020-01957-2 PMC 바로가기 [Article Type] Research Article
Statistical power in COVID-19 case-control host genomic study designCOVID-19 사례 대조군 숙주 게놈 연구 설계의 통계적 힘Correspondence Published on 2020-12-282022-09-10 Journal: Genome Medicine [Category] MERS, SARS, 변종, 유전자 메커니즘, 치료기술, [키워드] Accuracy Case-control COVID-19 detect disease severity disease severity of COVID-19 early stage early stages effect sizes Epidemiology estimate Factor feasibility Genetic Genetic epidemiology genetic factors genetic finding genetic findings Genetic studies Genetic variant Genetic variation Genome-wide association studies genomic Host Impact Infection Infectious disease information Interpretation moderate pandemic phenotypic data risk stratification SARS-CoV-2 SARS-COV-2 infection severity significantly Simulation Statistical genetics Study design supplementary material susceptibility therapeutic Treatment Vaccine development [DOI] 10.1186/s13073-020-00818-2 PMC 바로가기 [Article Type] Correspondence
Chest CT–derived pulmonary artery enlargement at the admission predicts overall survival in COVID-19 patients: insight from 1461 consecutive patients in ItalyChest Published on 2020-12-232022-10-31 Journal: European Radiology [Category] COVID-19, MERS, SARS, [키워드] adjusted Admission age analyzed association blinded Chest CT Clinical data Clinical findings Cohort cohort study consecutive patient COVID-19 COVID-19 patient COVID-19 patients creatinine CT measurement death in COVID-19 derivation enlargement evaluated extension Features final multivariable model Gender hazard ratio hospital hospitals Hypertension, pulmonary in-hospital mortality independent IQR Italy lung Lung CT main pulmonary artery male males Model Mortality multivariable Non-COVID-19 objective Patient performed Pneumonia Point predict Prognostic value pulmonary artery pulmonary hypertension regression analysis Result risk stratification Seven submitted supplementary material survival the median Thorax Tomography, X-Ray Computed validation cohort Volume was tested [DOI] 10.1007/s00330-020-07622-x PMC 바로가기 [Article Type] Chest
Adverse drug reactions in SARS-CoV-2 hospitalised patients: a case-series with a focus on drug–drug interactionsObservational Study Published on 2020-12-232022-10-04 Journal: Internal and Emergency Medicine [Category] MERS, SARS, 임상, [키워드] addition ADR ADRS Adverse drug reaction Adverse drug reactions age Caucasian patient Characteristics Clinical characteristics collected Comorbidities COVID-19 COVID-19 patient disorders drug–drug interaction Drug–drug interactions drugs effective evaluated Evidence Florence hospitalised hospitalised patient Hospitalised patients identify Interaction interactions internal medicine Italy less majority males medications outcome patients pharmacokinetic pharmacological pharmacovigilance preferred term Psychiatric QT interval QT prolongation reported resolved risk SARS-CoV-2 study period supplementary material treatments for COVID-19 unit university [DOI] 10.1007/s11739-020-02586-8 PMC 바로가기 [Article Type] Observational Study
Efficacy of Traditional Chinese Medicine, Maxingshigan-Weijing in the management of COVID-19 patients with severe acute respiratory syndrome: A structured summary of a study protocol for a randomized controlled trial중증 급성 호흡기 증후군이 있는 COVID-19 환자 관리에 대한 중국 전통 의학 Maxingshigan-Weijing의 효능: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2020-12-232022-08-31 Journal: Trials [Category] MERS, SARS, 임상, 치료제, [키워드] 1:1 acute respiratory syndrome acute respiratory syndrome coronavirus addition administration Affiliated Hospital age allergic allergies anorexia anti-bacterial Anti-viral anticipated Anxiety Arm asked Asymptomatic automatically aversion blinded Blinding Blood tinged blood tinged sputum both groups Care carried center checklist Chenpi chest pain chest X-ray Chinese Chinese Clinical Trial Registry Chinese herbal medicines clinical clinical symptom clinical trials clinically Cold comparator Patients composed control group Controlled trial coronavirus cough COVID-19 COVID-19 patient criteria critical patient critical patients defined diarrhea disease Diseases dissemination distension Dizziness dry mouth dysphoria effective Efficacy element Eligible patients ephedra exclusion criteria expectoration female Fever Follow-up four-point scale Gypsum H1N1 H1N1 influenza headache hematopoietic system Herba Ephedra herbal medicine hospital IBM IBM Corp IMPROVE improvement in both group include Inclusion inclusion and exclusion criteria inclusion criteria individual Influenza Informed consent Inpatient Insomnia Kaplan-Meier method kidney Kidney function lactation less liver log-rank test malaise male management Maxingshigan-weijing mechanical ventilation Medicine Melon Mild mild clinical symptoms multicenter multiple organ failure muscular nasal nasal obstruction nausea nausea and vomiting negative test nucleic acid number objective open Open-label oral administration outcome participant Patient patients Peach pharyngalgia Pneumonia positive Pregnancy previous study Primary outcome Professor proportion protocol Radix random random allocation random number generator randomisation randomised Randomized Randomized controlled trial randomly divided receive recruited registry reported researcher respiratory Respiratory failure respiratory symptom Sample size SARS-CoV-2 SARS-CoV-2 nucleic acid Scoring second secondary Secondary outcomes Semen sequence severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severity Shock Shortness of breath statistical analysis Statistical power Statistics status Study protocol suffering supplementary material supportive care survival survival time sweating Symptom symptomatic Symptoms System TCM temperature test results the median therapy total score Traditional Traditional Chinese medicine treated Treatment trial protocol Trial registration Trichosanthe Trichosanthes Kirilowii university USA Version virus pneumonia vomiting website wheezing Winter Withdrawal [DOI] 10.1186/s13063-020-04970-3 PMC 바로가기 [Article Type] Letter
Impact of COVID-19 on pediatric emergencies and hospitalizations in SingaporeResearch Article Published on 2020-12-232022-10-28 Journal: BMC Pediatrics [Category] COVID-19, MERS, SARS, [키워드] 95% CI 95% confidence interval 95%CI age analyzed baseline Blood category Child children CIs condition Coronavirus disease 2019 COVID-19 decrease diagnose diagnostic Gastrointestinal infection greater Guidance Health Service Health services hospital Hospital admission Hospitalization hospitalizations Impact impacted lockdown Pandemics pediatric per day performed proportion reduction in resource Resource utilization response Result retrospective significant decrease Singapore Standard deviation supplementary material System [DOI] 10.1186/s12887-020-02469-z PMC 바로가기 [Article Type] Research Article