Comparative analysis of COVID-19 guidelines from six countries: a qualitative study on the US, China, South Korea, the UK, Brazil, and HaitiResearch Article Published on 2020-12-032022-10-28 Journal: BMC Public Health [Category] COVID-19, MERS, [키워드] affecting Analysis analyzed Brazil China Clinical sign Community Comparative analysis Comparisons concern confirmed case Contact tracing coronavirus country COVID-19 COVID-19 cases COVID-19 guideline COVID-19 pandemic criteria Critical decrease dependent on document dramatic increase Emergency exploratory Factor General population Government Government guidelines Guidance Haiti healthcare Healthcare professional healthcare professionals Healthcare system Healthcare systems highlight identify initial National outbreak Outbreak COVID-19 pandemic Prevent proportions PROTECT Public resource Result sick similarity social distancing South Korea Spread spread of COVID-19 Stage supplementary material symptoms of COVID-19 the WHO Threats worldwide crisis [DOI] 10.1186/s12889-020-09924-7 PMC 바로가기 [Article Type] Research Article
The effect of propolis supplementation on clinical symptoms in patients with coronavirus (COVID-19): A structured summary of a study protocol for a randomised controlled trial코로나바이러스(COVID-19) 환자의 임상 증상에 대한 프로폴리스 보충제의 효과: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Randomized Controlled Trial Published on 2020-12-032022-08-13 Journal: Trials [Category] MERS, SARS, 임상, [키워드] 1:1 age All participants anticipated Arm baseline Blinding block size calculated categories Cellulose changes in clinical clinical symptom Clinical symptoms Clinicians color concealed control group coronavirus coronavirus disease COVID-19 Date dissemination double-blind element eligible hospital Intervention intervention group investigator investigators Iran labelling microcrystalline microcrystalline cellulose name number objective odor outcome Parallel Arm participant Participants Patient patients PCR test performed pharmaceutical phase Placebo placebo-controlled clinical trial Propolis protocol Protocol study provided randomised controlled trial randomization randomization list randomization sequence Randomized Randomly receive recruited Registered registration number Reyhan Sample size sealed sensitivity sequence severity Sex shape stratified Study protocol supplementary material Tablet Taste total sample size Trial Trial registration Version Warfarin website weight [DOI] 10.1186/s13063-020-04934-7 PMC 바로가기 [Article Type] Randomized Controlled Trial
A COVID-19 call center for healthcare providers: dealing with rapidly evolving health policy guidelinesOriginal Research Article Published on 2020-12-022022-10-30 Journal: Israel Journal of Health Policy Research [Category] COVID-19, MERS, [키워드] addressed analyzed Call centers Care center Characteristics clinics communication Control COVID-19 COVID-19 cases COVID-19 outbreak criteria database date and time early response expected facilitate Guidance Health Health authority Health care worker healthcare healthcare professionals Healthcare provider home quarantine hospital implementation indicate involved management median Medical conditions MOST Nurse outcome Pandemics/prevention and control peaking physician Physicians Precaution primary care public health question ranged Real-time analysis resolved response Result SARS-CoV2 seeking supplementary material Symptomatic patients Travel Volume were recorded [DOI] 10.1186/s13584-020-00433-x PMC 바로가기 [Article Type] Original Research Article
Development of machine learning models to predict RT-PCR results for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in patients with influenza-like symptoms using only basic clinical data기초 임상 데이터만으로 인플루엔자 유사 증상 환자에서 중증급성호흡기증후군 코로나바이러스 2(SARS-CoV-2)에 대한 RT-PCR 결과를 예측하는 머신러닝 모델 개발Original Research Published on 2020-12-012022-09-12 Journal: Scandinavian Journal of Trauma, Resuscitation and [Category] MERS, SARS, 진단, [키워드] Accuracy acute respiratory syndrome age Algorithm approach artificial intelligence best carried chain Chain Reaction Clinical data Combination coronavirus coronavirus 2 Critical care development Diagnosis diagnostic eligibility Emergency Departments Emergency service, hospital hand hospital Hospital admission Implications IMPROVE Influenza influenza-like symptom Influenza-like symptoms information input Italy laboratory data leukocyte machine learning machine learning model management median men not performed Pandemics Patient performed positive predict protocol radiological reached reaction respiratory Result Retrospective study RT-PCR SARS-CoV-2 screened sensitivity Severe acute respiratory syndrome severe acute respiratory syndrome coronavirus 2 specificity subject Supervised machine learning supplementary material System tested Testing training were excluded [DOI] 10.1186/s13049-020-00808-8 PMC 바로가기 [Article Type] Original Research
Pervasive generation of non-canonical subgenomic RNAs by SARS-CoV-2SARS-CoV-2에 의한 비정규 서브게놈 RNA의 광범위한 생성Research Published on 2020-12-012022-08-13 Journal: Genome Medicine [Category] MERS, SARS, 유전자 메커니즘, [키워드] 3′ end 5′ UTR abundance accessory protein addition Analysis approaches canonical canonical sgRNA canonical sgRNAs caused Cell culture condition Consistency Coordinate coronavirus disease Coronavirus disease 2019 Coverage COVID-19 determine Direct RNA sequencing eight Evidence family Coronaviridae FIVE generate Genome highlight homology Host identify in viral increase in independent Infection information Integrative analysis junction landscape leader sequence make up nc-sgRNA nc-sgRNAs non-canonical sgRNA non-canonical sgRNAs non-canonical subgenomic RNA offer open reading frames ORF ORF1a ORFs positive-sense RNA virus Region reported Result RNA RNA virus SARS-CoV-2 SARS-CoV-2 biology SARS-CoV-2 genome SARS-CoV-2 pathogenesis SARS-CoV-2 RNA SARS-CoV-2 sgRNA SARS-CoV-2 sgRNAs SARS-CoV-2 transcriptome SARS-CoV-2 transcriptomes sequence sequences Sequencing Seven sgRNA sgRNAs subgenomic RNA subgenomic RNAs supplementary material the SARS-CoV-2 genome Transcription transcriptional activity transcriptional regulatory sequence transcriptional regulatory sequences transcriptomes TRS TRS-B TRS-L Viral viral isolate viral isolates viral RNAs was used worldwide pandemic [DOI] 10.1186/s13073-020-00802-w PMC 바로가기 [Article Type] Research
Altered nutrition behavior during COVID-19 pandemic lockdown in young adultsOriginal Contribution Published on 2020-12-012022-11-01 Journal: European Journal of Nutrition [Category] COVID-19, MERS, SARS, [키워드] acquisition Adults affected age alcohol All participant Alter alteration Altered asked BMI body mass index cardiovascular prevention Comorbidity Complete COVID-19 pandemic COVID-19 pandemic lockdown cross-sectional dietary habits eating behavior Effect enrolled evaluate increase information less lockdown male male participant measure Mental obesity pandemic participant Primary outcome questionnaire reduced Regression model Result risk SARS-CoV-2 secondary outcome significantly Stress students study cohort subject supplementary material triggered [DOI] 10.1007/s00394-020-02435-6 PMC 바로가기 [Article Type] Original Contribution
Specific dynamic variations in the peripheral blood lymphocyte subsets in COVID-19 and severe influenza A patients: a retrospective observational studyCOVID-19 및 중증 인플루엔자 A 환자의 말초 혈액 림프구 하위 집합의 특정 동적 변화: 후향적 관찰 연구Observational Study Published on 2020-12-012022-09-10 Journal: BMC Infectious Diseases [Category] MERS, SARS, 유전자 메커니즘, 임상, [키워드] (T cells Affect alteration Blood donors CD4 CD8 change Clinical significance Comorbidities contribute Coronavirus disease-19 (COVID-19) COVID-19 determine different time point different time points Disease progression early infection examined Flow cytometric analysis four group four groups healthy blood donors healthy controls healthy donor healthy donors hospital immune mechanism increased mortality Influenza influenza A leukocytes lymphocyte Lymphocyte subset Lymphocyte subsets Lymphocytes Patient patients’ data performed Peripheral blood Prognosis Result retrospective severe COVID-19 Severe influenza A significantly lower Specific stages supplementary material T cell T cells T cells subsets the patient turn Variation [DOI] 10.1186/s12879-020-05637-9 PMC 바로가기 [Article Type] Observational Study
Impact of SARS-CoV-2 Pandemic on Patients with Primary ImmunodeficiencyOriginal Article Published on 2020-12-012022-10-30 Journal: Journal of Clinical Immunology [Category] COVID-19, MERS, SARS, [키워드] age combined immunodeficiency condition COVID-19 diagnosed immune dysregulation immunodeficiency Immunomodulatory agents Impact IMPROVE incidence infected individual infections less life-threatening management mortality rate National pandemic Patient Pediatric patient PID Primary Immunodeficiency Prospective Study SARS-CoV-2 Severe viral infection Stem cell transplantation supplementary material survival rate [DOI] 10.1007/s10875-020-00928-x PMC 바로가기 [Article Type] Original Article
Knowledge, attitudes and practices of the Chinese public with respect to coronavirus disease (COVID-19): an online cross-sectional surveyResearch Article Published on 2020-11-302022-10-28 Journal: BMC Public Health [Category] COVID-19, [키워드] addition affected age Analysis Attitude average China Chinese conducted coronavirus disease COVID-19 cross-sectional cross-sectional survey disease Diseases evaluate exhibited Factor Gender had no independent KAP knowledge Multiple linear regression pandemic positive attitude Practice question questionnaire ranged Result supplementary material survey t-test [DOI] 10.1186/s12889-020-09961-2 PMC 바로가기 [Article Type] Research Article
Low dose of emetine as potential anti-SARS-CoV-2 virus therapy: preclinical in vitro inhibition and in vivo pharmacokinetic evidencesResearch Published on 2020-11-302022-10-30 Journal: Molecular Biomedicine [Category] COVID-19, [키워드] addition anti-SARS-CoV-2 Anti-SARS-CoV-2 infection therapy Antiviral clinical investigation clinically Concentration COVID-19 disease dose drug effective effective therapy Emetine Evidence global pandemic IL-6 in vitro in vivo Infection inhibit SARS-CoV-2 interleukin-6 low dose LPS lung lung tissue macrophages mice Necrosis new coronavirus SARS-CoV-2 Old drug repurposing pharmacokinetic protein level reduce Replication safety profile significantly supplementary material target tissue therapy THP-1 TNF-α Vero Cell virus virus entry virus replication [DOI] 10.1186/s43556-020-00018-9 PMC 바로가기 [Article Type] Research