In Vitro Virucidal Effect of Intranasally Delivered Chlorpheniramine Maleate Compound Against Severe Acute Respiratory Syndrome Coronavirus 2
Allergy/Immunology
[키워드] acute respiratory syndrome
Against
analysis of variance
ANOVA
Antiviral
antiviral activity
Antiviral effect
average
calculated
CCID
Cell culture
Chlorpheniramine
chlorpheniramine maleate
clinical trials
Compound
Contact
Control
coronavirus
coronavirus 2
COVID-19
COVID-2019
CPM
determine
dose
Effect
effective
endpoint titer
genome sequence
GraphPad Prism
hospitalized patient
Hydroxychloroquine
in vitro
independent
infected cells
Infection
Influenza
initial
intranasal
intranasally
Log reduction
medication
MERS-CoV
Middle East
Mild-to-moderate
nasal
Nasal spray
novel coronavirus disease
outbreak
pandemic
Patient
placebo-controlled study
Randomized
reduced
reduction in
replicate
respiratory
respiratory syndrome coronavirus
responsible
Result
Safe
SARS-CoV
SARS-CoV-2
similarity
Standard deviation
statistically significant
strain
tested
Treatment
USA-WA1/2020
Vero
Viral load
virucidal
virus
was tested
[DOI] 10.7759/cureus.10501 PMC 바로가기 [Article Type] Allergy/Immunology
[DOI] 10.7759/cureus.10501 PMC 바로가기 [Article Type] Allergy/Immunology