Critical – Page 23 – Communicable Diseases Research

The Kinetics of SARS-CoV-2 Antibody Development Is Associated with Clearance of RNAemia

Article

Published on 2022-08-302022-11-15
Journal: mBio [Category] COVID19(2023년), SARS, 진단,

[키워드] accelerated antibody baseline binding binding activity binding antibody Characteristics clearance COVID-19 COVID-19 disease COVID-19 disease severity Critical death defined development disease disease severity dissemination effective Evolution examined FcγR feature function highlight humoral humoral immune response IgG IgG3 immune immune clearance immune function Immune profile independent Kinetics Longitudinal data longitudinal data modeling maturation monoclonal Mortality natural infection neutralization outcome persistence persistent persistent SARS-CoV-2 plasma viremia plasma predict progression provide SARS-CoV-2 SARS-CoV-2 replication severe COVID-19 Specificities subunit system serology viral clearance viral replication Viremia
[DOI] 10.1128/mbio.01577-22 PMC 바로가기

Genetic Surveillance of SARS-CoV-2 Mpro Reveals High Sequence and Structural Conservation Prior to the Introduction of Protease Inhibitor Paxlovid

Article

Published on 2022-08-302022-11-15
Journal: mBio [Category] COVID19(2023년), SARS, 변종, 치료제,

[키워드] 3CLpro acute respiratory syndrome Analysis analyzed Antiviral antiviral drug Antiviral treatment antivirals baseline binding circulating cleavage clinical response conservation conserved Contact Coronaviral Coronaviridae family coronavirus COVID-19 COVID-19 pandemic Critical database determine drug target effort Emergency use authorization enzyme escape mutation EUA Evolution expected Genetic genomic GISAID globe health emergency implication inhibitor inhibitors initiative introduced isolate isolates M pro motifs MPro Mutation Nirmatrelvir pandemic progresse Paxlovid protease purifying selection raise reference sequence Region remained residue retrieved robust SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 Mpro SARS-CoV-2 viral selective sequence Sequencing starting point Surveillance the SARS-CoV-2 the spike protein Treatment unique variants variants of SARS-CoV-2 virus widespread Wuhan-Hu-1
[DOI] 10.1128/mbio.00869-22 PMC 바로가기

The RING finger protein family in health and disease

Reviews

Published on 2022-08-302022-10-05
Journal: Signal Transduction and Targeted Therapy [Category] 변종, 유전자 메커니즘, 치료제,

The role of electrolyte imbalances in predicting the severity of COVID-19 in the hospitalized patients: a cross-sectional study

Research

Published on 2022-08-302022-10-05
Journal: Scientific Reports [Category] SARS, 치료법,

Impact of SARS-CoV-2 Spike Mutations on Its Activation by TMPRSS2 and the Alternative TMPRSS13 Protease

Article

Published on 2022-08-302022-11-16
Journal: mBio [Category] SARS, 변종, 치료기술,

[키워드] 229E Activation acute respiratory syndrome affected airway being benefit Calu-3 cell change changes in cleavage conserved coronavirus creating Critical Delta dibasic experiment favor functional fusion peptide had no help host cell human coronavirus 229E humans immune evasion immunogenic Impact influence less MERS-CoV Middle East motif mutant Mutation mutations new SARS-CoV-2 no difference omicron pathogenic protease Proteases Protein pseudovirus pseudovirus entry reduced remained residue residues respiratory syndrome coronavirus reverse effect SARS-CoV-2 SARS-CoV-2 spike sequence shown spike spike functioning Spike protein Surveillance the SARS-CoV-2 TMPRSS13 TMPRSS13 protease TMPRSS2 Tolerance variant variants Variation virus entry Wuhan-Hu-1
[DOI] 10.1128/mbio.01376-22 PMC 바로가기

Airway-resident T cells from unexposed individuals cross-recognize SARS-CoV-2

Article

Published on 2022-08-292022-10-05
Journal: Nature Immunology [Category] SARS, 임상, 진단, 치료기술,

Evolution of Anti-SARS-CoV-2 Therapeutic Antibodies

Article

Published on 2022-08-282022-11-15
Journal: International Journal of Molecular Sciences [Category] SARS, 변종, 진단,

Planning and Reporting Effective Web-Based RAND/UCLA Appropriateness Method Panels: Literature Review and Preliminary Recommendations

Article

Published on 2022-08-262022-11-16
Journal: Journal of Medical Internet Research [Category] 변종,

[키워드] Affair approach Care category Characteristics Clinical presentations Clinicians Conducting COVID-19 pandemic Critical database de-implementation DelPhi Department Digital health elicit eligibility criteria evaluate Evidence example Guidance Health Health care health research Health technology identify IMPROVE involved less literature literature review measure medical professionals participant Planning primary care producing quality indicators RAND/UCLA appropriateness method recommendation reported Reporting reproducibility Research Research design researcher researchers review Safe Satisfaction searched seeking study outcomes the median Treatment variant veteran Virtual virtual health research Web-based while
[DOI] 10.2196/33898 PMC 바로가기

Strategic COVID-19 vaccine distribution can simultaneously elevate social utility and equity

Research

Published on 2022-08-252022-10-05
Journal: Nature human behaviour [Category] 치료법,

[키워드] association balancing Community complex COVID-19 COVID-19 pandemic COVID-19 vaccine Critical distribution Epidemic equity evaluate example feature Health heterogeneous less provide risk utility Vaccination strategies Vaccine
[DOI] 10.1038/s41562-022-01429-0 [Article Type] Research

Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance

Research

Published on 2022-08-252022-10-05
Journal: Nature Communications [Category] 변종, 치료제,