endothelial – Page 23 – Communicable Diseases Research

Genetic risk for severe COVID‐19 correlates with lower inflammatory marker levels in a SARS‐CoV‐2‐negative cohort

Original Article

Published on 2021-06-062022-10-31
Journal: Clinical & Translational Immunology [Category] COVID-19,

[키워드] acute respiratory syndrome Adaptive immune response Affect age Alpha applied association baseline baseline level Blood Blood level body mass index Cohort coronavirus coronavirus disease COVID‐19 COVID‐19 patients COVID‐19 cytokine Effect electrochemiluminescence method endothelial explain genetic risk genetic risk score genotype data growth factor hypothesise IFN‐γ IFN‐γ increasingly individual Infection Inflammation Inflammatory Inflammatory marker inflammatory markers inflammatory protein Innate immunity interferon gamma marker Necrosis obesity objective overactive profile reduced Result risk SARS‐CoV‐2 SARS‐CoV‐2 serum Support susceptibility susceptible the cytokine storm TNF‐α TNF‐α variable Vascular
[DOI] 10.1002/cti2.1292 PMC 바로가기 [Article Type] Original Article

Rapid endotheliitis and vascular damage characterize SARS-CoV-2 infection in a human lung-on-chip model

급속한 내피염 및 혈관 손상은 인간 폐 온칩 모델에서 SARS-CoV-2 감염을 특징짓습니다

Article

Published on 2021-06-042022-09-11
Journal: EMBO Reports [Category] SARS, 치료기술,

[키워드] absence alveolar alveolar epithelial cell alveolar epithelial cells alveolar models CD31 cell cluster cell clusters characterized ChIP COVID-19 Cytokine storm endothelial Endothelial cell endothelial cell damage endothelial cells Endotheliitis epithelial cell epithelial cells expression IL-6 immune immune cells individual cell individual cells Infection Inflammatory response inhibition interleukin interleukin-6 lung microenvironment occur organ organ-on-chip persist Prevent Protein Rapid reduce RNA SARS-COV-2 infection secretion severe cases Tocilizumab Vascular damage Vasculitis Viral RNA virions
[DOI] 10.15252/embr.202152744 PMC 바로가기 [Article Type] Article

Beneficial Effects of Mineralocorticoid Receptor Pathway Blockade against Endothelial Inflammation Induced by SARS-CoV-2 Spike Protein

Article

Published on 2021-06-032022-10-28
Journal: Biomedicines [Category] COVID-19,

In silico Nigellidine (N. sativa) bind to viral spike/active-sites of ACE1/2, AT1/2 to prevent COVID-19 induced vaso-tumult/vascular-damage/comorbidity

인실리코 니겔리딘(N. sativa)은 ACE1/2, AT1/2의 바이러스 스파이크/활성 부위에 결합하여 COVID-19 유발 혈관 손상/혈관 손상/동반 질환을 예방합니다

Article

Published on 2021-06-012022-08-31
Journal: Vascular pharmacology [Category] MERS, SARS, 신약개발, 진단, 치료제,

Potential value of circulating endothelial cells for the diagnosis and treatment of COVID-19

COVID-19 진단 및 치료를 위한 순환 내피 세포의 잠재적 가치

Article

Published on 2021-06-012022-09-11
Journal: International Journal of Infectious Diseases [Category] MERS, SARS, 바이오마커, 치료법,

Direct hemoperfusion using a polymyxin B-immobilized polystyrene column for COVID-19

COVID-19에 대해 폴리믹신 B 고정 폴리스티렌 컬럼을 사용한 직접 혈액 관류

Observational Study

Published on 2021-06-012022-09-11
Journal: Journal of clinical apheresis [Category] 바이오마커, 임상,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 avoidance Biomarker Case series case sery categories circuit Coagulation conducted coronavirus COVID-19 cytokine D-dimer defined Degradation Degradation product determine DHPs Direct direct hemoperfusion disease severity Efficacy Efficacy and safety eight endothelial endothelial injury evaluate evaluated expected extracorporeal membrane oxygenation Factor FIBRIN fibrin degradation product FIVE Future growth factor Hemoperfusion high risk hospital Hospitalization Infectious disease Infectious diseases interleukin-6 involved malfunctions membrane membranes microglobulin oxygen P/F P/F ratio partial pressure partial pressure of arterial oxygen patients performed Pneumonia Polymyxin B polystyrene problem respiratory SARS-CoV-2-positive patient Seven severe acute respiratory syndrome Coronavirus Steroids therapeutic effect treated Treatment Urine Vascular vascular endothelial growth factor ventilator was performed
[DOI] 10.1002/jca.21861 PMC 바로가기 [Article Type] Observational Study

Extracellular Vesicles: Versatile Nanomediators, Potential Biomarkers and Therapeutic Agents in Atherosclerosis and COVID-19-Related Thrombosis

세포외 소포: 죽상경화증 및 COVID-19 관련 혈전증에서 다목적 나노매개체, 잠재적 바이오마커 및 치료제

Review

Published on 2021-05-312022-09-10
Journal: International Journal of Molecular Sciences [Category] 바이오마커,

[키워드] agent atherogenesis Atherosclerosis atherosclerotic Biomarker Biomarkers cardiovascular disease cardiovascular diseases cargo Cell cells Characteristics coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient cytoplasmic proteins DNA Effect endocytosis endothelial EVs Exosomes extracellular vesicle Extracellular vesicles immune cells information mechanism mediators Mesenchymal stromal cells metabolites microRNA Microvesicles mRNA participant pathological condition Pathologies Platelets Potential receptors Signaling stromal cells therapeutic agents therapeutic potential thrombosis thrombotic Thrombotic events transfer variety
[DOI] 10.3390/ijms22115967 PMC 바로가기 [Article Type] Review

Exosomes contribution in COVID-19 patients’ treatment

Commentary

Published on 2021-05-312022-10-30
Journal: Journal of Translational Medicine [Category] COVID-19, SARS,

Extensive Coronary Thrombosis as a Sequelae of COVID-19 Presenting as a STEMI

Cardiology

Published on 2021-05-262022-10-31
Journal: Cureus [Category] COVID-19,

Longitudinal in vivo imaging of acute neuropathology in a monkey model of Ebola virus infection

Article

Published on 2021-05-172022-10-04
Journal: Nature Communications [Category] 바이오마커,