Cost-effectiveness of a Telemonitoring Program for Patients With Heart Failure During the COVID-19 Pandemic in Hong Kong: Model Development and Data AnalysisOriginal Paper Published on 2021-03-032022-10-30 Journal: Journal of Medical Internet Research [Category] Coronavirus, SARS, [키워드] addition Analysis appear assumption Care caused Cohort cost-effectiveness COVID-19 COVID-19 pandemic demonstrated development Effectiveness failure Health health care avoidance heart heart failure Hong Kong hypothetical management Markov Mobile health Model objective older patient outcome outcome measure Patient performed Perspective Program Result seeking sensitivity analysis Smartphone Telemonitoring threshold threshold value usual care [DOI] 10.2196/26516 PMC 바로가기 [Article Type] Original Paper
Failure of chronic hydroxychloroquine in preventing severe complications of COVID-19 in patients with rheumatic diseasesConcise Report Published on 2021-03-022022-10-28 Journal: Rheumatology Advances in Practice [Category] COVID-19, [키워드] 95% CI Admission age baseline characteristics clinical presentation Comorbidities condition Control control subject control subjects controls coronavirus disease COVID-19 COVID-19 in patient demographics diabete disease dosages failure groups HCQ HCQ therapy hospital Hospitalization hospitalized patient Hydroxychloroquine in-hospital mortality individual IQR less Logistic regression Lupus mechanical ventilation median age medications New York City obesity objective outcome Patient pre-exposure prophylaxis Prednisone Prevalence preventive proportion pulmonary disease receive receiving reported Result rheumatic disease rheumatoid arthritis rheumatologic diseases severe complication statistically significant difference subject with COVID-19 [DOI] 10.1093/rap/rkab014 PMC 바로가기 [Article Type] Concise Report
Mechanical ventilation and mortality among 223 critically ill patients with coronavirus disease 2019: A multicentric study in GermanyObservational Study Published on 2021-03-012022-10-05 Journal: Australian critical care : official journal of the Confederation of [Category] SARS, 임상, [키워드] Admission age antiviral therapy ARDS assessment Characteristics Complication coronavirus disease Course COVID-19 Critically ill patient demographics discharge evaluated extracorporeal membrane oxygenation failure Germany groups Hamburg heart failure hospital ICU initiated intensive care interquartile range majority Mechanical mechanical ventilation mechanically ventilated patients median Mortality multicentre Multiple multiple organ failure nasal noninvasive Observational cohort study organ outcome Patient patients patients with COVID-19 retrospective SARS-CoV-2 Septic shock severe respiratory failure severity survival the median therapy Ventilation was performed was used were used with COVID-19 [DOI] 10.1016/j.aucc.2020.10.009 PMC 바로가기 [Article Type] Observational Study
Myocardial Injury on Admission as a Risk in Critically Ill COVID-19 Patients: A Retrospective in-ICU StudyObservational Study Published on 2021-03-012022-10-05 Journal: Journal of cardiothoracic and vascular anesthesia [Category] 임상, [키워드] 28-day mortality 95% CI 95% confidence interval Admission assessment cardiac troponin cardiovascular complication chronic Clinical characteristics Clinical outcome Comorbidity complications COVID-19 critical COVID-19 patients Critically ill Critically ill patient CV complication CV complications demographic disease evaluated failure hazard ratio high risk hospital ICU Ill incidence increased the risk Injury Inpatient intensive care interquartile range IQR Laboratory tests measurement Mortality mortality risk Myocardial myocardial injury novel coronavirus disease novel coronavirus disease. Older Patient patients Physiology Prevalence retrospective risk factor Science severity single-center stratified technology Treatment university with COVID-19 Wuhan, China [DOI] 10.1053/j.jvca.2020.10.019 PMC 바로가기 [Article Type] Observational Study
Entry, egress and vertical transmission of SARS-CoV- 2SARS-CoV-2의 진입, 퇴장 및 수직 전송Review Published on 2021-03-012022-09-10 Journal: Journal of Molecular Cell Biology [Category] SARS, 유전자 메커니즘, 진단, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adults caused children clinical manifestation clinical manifestations coronavirus COVID-19 COVID-19 outbreak demonstrated destruction disease effective entry of SARS-CoV-2 Evidence failure Fatality rate host cells life lung Lungs Mild molecular mechanism much lower Neonate other organ other organs pandemic Pandemics pathogenicity placental transmission pregnant women Psychological recent respiratory SARS-CoV SARS-CoV-2 severe acute respiratory syndrome Coronavirus TMPRSS2 TRAIL Transmission transmission of SARS-CoV-2 vertical transmission widespread [DOI] 10.1093/jmcb/mjab013 PMC 바로가기 [Article Type] Review
Hydroxychloroquine for treatment of nonsevere COVID-19 patients: Systematic review and meta-analysis of controlled clinical trials중증이 아닌 COVID-19 환자의 치료를 위한 Hydroxychloroquine: 대조 임상 시험의 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-03-012022-09-11 Journal: Journal of medical virology [Category] 임상, [키워드] 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus-2 adverse effect adverse effects age arising authors being bias risk Case fatality rate clearance clinical benefit clinical benefits clinical evidence clinical trial clinical trials confidence interval Controlled clinical trial coronavirus coronavirus disease Coronavirus-2 COVID-19 COVID-19 confirmed patient COVID-19 patients COVID-19 progression data extraction determine Efficacy ENhance Evidence failure Fatality rate Hydroxychloroquine hydroxychloroquine therapy inclusion criteria independent Intervention Meta-analysis Mortality pandemic Patient Pharyngeal swab polymerase chain polymerase chain reaction Prevent Primary outcome Primary outcomes progression protective effect radiological radiological progression reduce reported risk Risk assessment risk difference secondary outcome Secondary outcomes Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus significantly Treatment usual care viral clearance [DOI] 10.1002/jmv.26442 PMC 바로가기 [Article Type] Meta-Analysis
Immune Response Failure in Paucisymptomatic Long-Standing SARS-CoV-2 SpreadersCase Report Published on 2021-03-012022-10-31 Journal: Clinics and Practice [Category] COVID-19, [키워드] acute respiratory syndrome Analysis caused clinical picture clinically coronavirus coronavirus disease COVID-19 death demonstrated disease disease severity example failure greater Hospital stay Immune cell immune response immune system immune system deficiency impair lack large sample mechanism multiparametric flow cytometry outcomes Patient paucisymptomatic patients persistence Perspective positive presenting public health Quantitative quarantine question reduction in response SARS-CoV-2 Spread spreader Swab test viral persistence virus [DOI] 10.3390/clinpract11010021 PMC 바로가기 [Article Type] Case Report
Effect of early treatment with polyvalent immunoglobulin on acute respiratory distress syndrome associated with SARS-CoV-2 infections (ICAR trial): study protocol for a randomized controlled trialSARS-CoV-2 감염과 관련된 급성 호흡 곤란 증후군에 대한 다가 면역글로불린의 조기 치료 효과(ICAR 시험): 무작위 대조 시험을 위한 연구 프로토콜Study Protocol Published on 2021-02-282022-09-01 Journal: Trials [Category] MERS, 임상, 진단, [키워드] 1:1 90% power activities activity acute respiratory distress acute respiratory distress syndrome administration adverse event Alpha ARDS assessment chloride coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 daily living defined died double-blind early treatment Effect effect size Efficacy and safety EudraCT evaluate evaluate the effect failure France functional GRADE grade 3 Hospital stay Hospitalized ICU Immunoglobulin immunomodulatory increase in intensive care intensive care unit Intravenous immunoglobulin IVIG Lung injury mechanical ventilation morbidity mortality rate multicenter Occurrence Organ failure outcome parallel group participant Patient pharmacological treatment placebo group Polyvalent immunoglobulin Primary outcome Randomized Randomized controlled trial receive reduction in respiratory distress SARS-CoV-2 SARS-COV-2 infection Secondary objective Secondary objectives sequential design Sodium chloride SOFA Study protocol subject survival survival rate syndrome the placebo group treatment group Trial Trial registration ventilator-free day Ventilator-free days Volume were infected with COVID-19 [DOI] 10.1186/s13063-021-05118-7 PMC 바로가기 [Article Type] Study Protocol
Outcome Prediction in Patients with Severe COVID-19 Requiring Extracorporeal Membrane Oxygenation—A Retrospective International Multicenter StudyArticle Published on 2021-02-272022-10-31 Journal: Membranes [Category] COVID-19, [키워드] Accuracy acute respiratory distress acute respiratory distress syndrome APACHE II ARDS assessment Belgium benefit calculated chronic Cohort COVID-19 COVID-19 patient criteria cut-off value defined enrolled evaluate Extracorporeal extracorporeal membrane oxygenation failure Germany International invasive investigator-initiated Italy large cohort Mortality multicenter multicenter study non-COVID-19 ARDS patient Patient patients patients treated Physiology predict prediction Prognosis prognostic ranged Registered reported respiratory retrospective SARS-CoV-2 score severe COVID-19 SOFA study cohort survival Switzerland syndrome The United States therapy treated Treatment V-V ECMO [DOI] 10.3390/membranes11030170 PMC 바로가기 [Article Type] Article
A Comprehensive Review of Viral Characteristics, Transmission, Pathophysiology, Immune Response, and Management of SARS-CoV-2 and COVID-19 as a Basis for Controlling the Pandemic전염병 통제를 위한 기초로서 SARS-CoV-2 및 COVID-19의 바이러스 특성, 전파, 병태생리학, 면역 반응 및 관리에 대한 종합적인 검토Review Published on 2021-02-262022-09-11 Journal: Frontiers in Immunology [Category] MERS, 변종, 치료제, [키워드] Antarctica anti-inflammatory drug approved Asymptomatic Basis causative pathogen children China clinical presentation Clinical presentations Comprehensive controlling coronavirus country COVID vaccines COVID-19 curative Dexamethasone drug drugs effective facilitate failure Genome globe Healthcare system Healthcare systems Hydroxychloroquine immune response infected case knowledge Mechanics mode Mortality negatively affected not reduce pathophysiology Patient positive Prevent promote provide Reinfection Remdesivir response review risk RNA polymerase inhibitor SARS-CoV-2 significantly Spread spread to susceptibility the disease Transmission Trial Vaccine development variants Variation variations virus virus transmission [DOI] 10.3389/fimmu.2021.631139 PMC 바로가기 [Article Type] Review