Learnings from the design and acceptance of the German COVID-19 tracing app for IS-driven crisis management: a design science researchResearch Article Published on 2021-08-092022-10-27 Journal: BMC Medical Informatics and Decision Making [Category] Coronavirus, COVID-19, MERS, SARS, [키워드] addition applied approach changes Corona-Warn-App COVID-19 creating crisis management Design science effective Effectiveness epidemiologist evaluate example flexible functional Germany Government group discussion Health Infection information International involved learning management Modification overcome pandemic participant prototype recommendation Research Result risk supplementary material tested Tracing apps transferred User experience design [DOI] 10.1186/s12911-021-01579-7 PMC 바로가기 [Article Type] Research Article
The pragmatic, rapid, and iterative dissemination and implementation (PRIDI) cycle: adapting to the dynamic nature of public health emergencies (and beyond)Opinion Published on 2021-08-042022-10-31 Journal: Health Research Policy and Systems [Category] COVID-19, MERS, SARS, [키워드] activities adaptive approach benefit Care Characteristics COVID-19 COVID-19 pandemic Critical D&I models diagnostic dissemination effective evaluate Evidence flexible Health health system implementation individual Intervention iterative mitigate outcomes Population Pragmatic Public public health public health emergencies public health emergency Rapid cycle recognize Support therapeutic [DOI] 10.1186/s12961-021-00764-4 PMC 바로가기 [Article Type] Opinion
The evolution of genetic counseling graduate education in New York City during the COVID-19 pandemic: In the eye of the stormCOVID-19 전염병 동안 뉴욕시에서 유전 상담 대학원 교육의 진화: 폭풍의 눈 속에서Article Published on 2021-08-012022-09-11 Journal: Journal of genetic counseling [Category] 유전자 메커니즘, [키워드] Admission change changes in counseling Course COVID-19 COVID-19 pandemic curriculum desire education energy Enrollment event Evolution flexibility flexible Genetic Genetic counseling globe Health profession identify implication improvement iterative life New York City outcome measures pandemic practitioner-based enquiry profession Program evaluation reactivity recruitment reduced relative required retention returned summer telehealth United State United States [DOI] 10.1002/jgc4.1461 PMC 바로가기 [Article Type] Article
Rapid and Flexible Platform To Assess Anti-SARS-CoV-2 Antibody Neutralization and Spike Protein-Specific AntiviralsAnti-SARS-CoV-2 항체 중화 및 스파이크 단백질 특이적 항바이러스제를 평가하기 위한 신속하고 유연한 플랫폼Research Article Published on 2021-07-282022-09-10 Journal: mSphere [Category] MERS, SARS, 변종, 진단, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus addition antibody Antiviral antiviral immunity approach Assessing binding biosafety biosafety level BSL2 BSL3 caused cDNA Cell Community complement condition conditions coronavirus COVID-19 pandemic evaluated flexible genetic information glycoprotein human sera human serum Immunity Infection level 2 MONITOR natural infection neutralization Neutralizing pandemic platform population immunity positive sample protocol pseudotyped Rapid respiratory Safe SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 spike protein screened sera shown spike Spike protein vaccination Vaccines variants variants of concern Viral viral envelope virus Virus neutralization virus-neutralizing viruses [DOI] 10.1128/mSphere.00571-21 PMC 바로가기 [Article Type] Research Article
AGILE: a seamless phase I/IIa platform for the rapid evaluation of candidates for COVID-19 treatment: an update to the structured summary of a study protocol for a randomised platform trial letterUpdate Published on 2021-07-262022-10-04 Journal: Trials [Category] SARS, 임상, [키워드] accelerate approved candidate clinical evaluation Cohort COVID-19 COVID-19 pandemic determine Dexamethasone dose drug early phase early stage Efficacy EudraCT evaluated flexible global healthcare healthy help Hospitalised patients identify information ISRCTN knowledge late phase later phase Master protocol National open label patients Phase I/II, Bayesian platform Platform study Platform trial primary endpoint protocol randomised randomised controlled trial recovery recruitment Remdesivir Safe Sample size SARS-CoV-2 SARS-COV-2 infection seamless Study protocol supplementary material Tocilizumab Treatment treatments for COVID-19 Trial trial platform trial protocol University of Oxford WHO [DOI] 10.1186/s13063-021-05458-4 PMC 바로가기 [Article Type] Update
Unified platform for genetic and serological detection of COVID-19 with single-molecule technology단일 분자 기술을 사용한 Covid-19의 유전자 및 혈청 학적 탐지를위한 통합 플랫폼Research Article Published on 2021-07-262022-09-10 Journal: PLoS ONE [Category] SARS, 진단, 치료기술, [키워드] adjusted antibodies approach COVID-19 COVID-19 pandemic detect diagnose diagnostic diagnostics enzyme flexible Genetic genetic material IgG and IgM IgM antibodies immune response Pathogens platform Quantitative raise SARS-CoV-2 serological Stage Viral viral infection [DOI] 10.1371/journal.pone.0255096 PMC 바로가기 [Article Type] Research Article
Structural Modeling of the SARS-CoV-2 Spike/Human ACE2 Complex Interface can Identify High-Affinity Variants Associated with Increased TransmissibilitySARS-CoV-2 스파이크/인간 ACE2 복합 인터페이스의 구조 모델링은 전파율 증가와 관련된 고친화도 변이를 식별할 수 있습니다.Article Published on 2021-07-232022-09-11 Journal: Journal of Molecular Biology [Category] SARS, 변종, [키워드] ACE2 affinity Analysis antibody antibody resistance Applying binding binding affinities binding affinity changes in circulating Cluster Combination combinatorial mutations complex complexes COVID-19 pandemic determine E484K Effect flexible functional G476S generate hACE2 help human ACE2 human ACE2 receptor Increased Infection Interaction interface Intervention K31 K353 modeling mutant Mutation N501Y pathogenic Point mutation predict predicted Protein Protein binding public health measure Region reveal S477N SARS-CoV-2 SARS-CoV-2 spike protein screening method sequence spike spike mutations Spike protein Structural analysis structural modeling susceptibility susceptibility to infection the SARS-CoV-2 Transmissibility transmissible variants transmissible variants. triggered variant variants Variation viral strains viral variant wild-type [DOI] 10.1016/j.jmb.2021.167051 PMC 바로가기 [Article Type] Article
Developing an Innovative System of Open and Flexible, Patient-Family-Centered, Virtual Visiting in ICU During the COVID-19 Pandemic: A Collaboration of Staff, Patients, Families, and Technology CompaniesAnalytic Reviews Published on 2021-07-222022-10-29 Journal: Journal of Intensive Care Medicine [Category] Coronavirus, MERS, SARS, [키워드] aligned Care collaboration company complex COVID-19 COVID-19 pandemic criteria demonstrated develop Developing facilitate Families flexible healthcare help HowRU ICU IMPROVE intensive care unit open and flexible visiting Patient patient family communication patient-family connect patient-family-centered care platform staff supported System tailored system of virtual visiting technology video conferencing virtual visiting Visiting visitor restrictions Webex [DOI] 10.1177/08850666211030845 PMC 바로가기 [Article Type] Analytic Reviews
Real-time monitoring of COVID-19 dynamics using automated trend fitting and anomaly detection자동화된 추세 피팅 및 이상 감지를 사용하여 COVID-19 역학의 실시간 모니터링Articles Published on 2021-07-192022-09-10 Journal: Philosophical Transactions of the Royal Society B: [Category] SARS, 치료기술, [키워드] trendbreaker Algorithm Analysis approach ASMODEE automated automatically available data best changes in country COVID-19 COVID-19 case COVID-19 incidence COVID-19 outbreak COVID-19 pandemic criterion Early detection England Epidemics excluded flare flexible hotspot incidence Infectious disease interval Intervention lockdown machine learning National Health Service NHS outbreak outlier outliers provide R package social distancing measures subsequent Surveillance to define Transmission [DOI] 10.1098/rstb.2020.0266 PMC 바로가기 [Article Type] Articles
Optimal Insertion Depth for Nasal Mid-Turbinate and Nasopharyngeal SwabsArticle Published on 2021-07-142022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] age Antigen antigen test calculated clinical evidence clinical validation COVID-19 COVID-19 test Denmark Depth determine Evidence false-negative flexible inferior turbinate insertion lack mid-turbinate sample nasal nasal swab nasopharyngeal nasopharyngeal sample Nasopharyngeal swab nasopharyngeal swab specimen nasopharyngeal swabs pandemic participant provide risk SARS-CoV-2 specimen Swab tested upper respiratory virus virus virus diagnostics [DOI] 10.3390/diagnostics11071257 PMC 바로가기 [Article Type] Article