Detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is influenced by the type of transport medium: Implications for diagnosis and monitoring중증급성호흡기증후군 코로나바이러스 2(SARS-CoV-2)의 검출은 수송매체의 종류에 영향을 받는다: 진단 및 모니터링에 대한 시사점Article Published on 2021-08-012022-09-11 Journal: International journal of clinical practice [Category] SARS, 치료기술, [키워드] acute respiratory syndrome CDC clinical utility coronavirus demonstrated detection Diagnosis diagnosis and monitoring discrepancy discrepant result discrepant results Follow-up guanidine medium molecular N genes Patient positive raising RNase P RT-PCR SARS-CoV-2 SARS-CoV2 Stage tested Transport transport medium Viral transport medium VTM [DOI] 10.1111/ijcp.14311 PMC 바로가기 [Article Type] Article
Measuring hygiene competence: the picture-based situational judgement test HygiKoResearch Article Published on 2021-07-302022-10-28 Journal: BMC Medical Education [Category] Coronavirus, SARS, [키워드] Analysis asked assessment can be used Care clinician competence competency COVID-19 pandemic cross-sectional Data analysis diagnostic Evidence Health health-care healthcare hygiene independent involved IRT item Item-response theory judgement medical doctors medium Nurse Nurses professional psychometric properties recognize reliability required Research response Result Self-report questionnaires Situational judgement test Test theory Validity verbal [DOI] 10.1186/s12909-021-02829-y PMC 바로가기 [Article Type] Research Article
Online-Delivered Group and Personal Exercise Programs to Support Low Active Older Adults’ Mental Health During the COVID-19 Pandemic: Randomized Controlled TrialRandomized Controlled Trial Published on 2021-07-302022-10-04 Journal: Journal of Medical Internet Research [Category] SARS, 임상, [키워드] addition Adults approach assessments baseline conducted Controlled COVID-19 COVID-19 pandemic Depression early stage Effect effect size Effects exercise group growth Health IMPROVE improvement inactive Intervention intervention effect magnitude maintain measure media medium Mental mental health objective Older online questionnaires outcome participant Participants physical physical activity Primary outcome Program provided Psychological psychological health Randomized Randomized controlled trial randomized trial recruited Registration Result Satisfaction secondary statistically significant Support Symptom Symptoms Trial women [DOI] 10.2196/30709 PMC 바로가기 [Article Type] Randomized Controlled Trial
Supporting scale-up of COVID-19 RT-PCR testing processes with discrete event simulation개별 이벤트 시뮬레이션으로 COVID-19 RT-PCR 테스트 프로세스의 확장 지원Research Article Published on 2021-07-292022-09-12 Journal: PLoS ONE [Category] MERS, 진단, [키워드] Analysis bottleneck bottlenecks change COVID-19 COVID-19 pandemic Critical equipment evaluate example expand facilitate feasible identify inhibited Intervention Isolation Laboratory medium molecular pandemic partnership PCR testing problem public health emergency required RT-PCR testing Safe SARS-CoV-2 RT-PCR state Support Supporting Swab swabs Testing the United State time-consuming trade-off trade-offs United States university Variability virucidal [DOI] 10.1371/journal.pone.0255214 PMC 바로가기 [Article Type] Research Article
SARS-CoV-2 Infected Pediatric Cerebral Cortical Neurons: Transcriptomic Analysis and Potential Role of Toll-like Receptors in PathogenesisSARS-CoV-2에 감염된 소아 대뇌 피질 뉴런: 전사체 분석 및 병인에서 유료 유사 수용체의 잠재적 역할Article Published on 2021-07-282022-09-10 Journal: International Journal of Molecular Sciences [Category] SARS, 유전자 메커니즘, [키워드] ACE2 caspase caspase 8 cells cerebral changes in chemokine chemokines children cortical COVID-19 neurological symptom COVID-19 neurological symptoms deregulation downregulated downregulation downstream ERK expression genes encoding human neuronal cells IKKε increase in increased expression infect infected with SARS-CoV-2 IRF3 JNK mechanism medium nervous system Neurological involvement Neurological symptoms Neuron neuronal next generation sequencing NF-κB Nod-like receptors not express Pathogenesis Pattern recognition pattern recognition receptor pediatric Potential receptor receptors replicate responsible role SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 protein SARS-CoV-2 proteins scavenger receptors Sequencing Signaling TLR TLR1 TLR4 TLR6 TLRs TMPRSS2 Toll-like receptor Toll-like receptors TRAF3 transcriptomic analysis transcriptomic profile upregulated upregulation Viral Viral RNA western blot [DOI] 10.3390/ijms22158059 PMC 바로가기 [Article Type] Article
The role of collaborative, multistakeholder partnerships in reshaping the health management of patients with noncommunicable diseases during and after the COVID-19 pandemicOriginal Article Published on 2021-07-282022-10-28 Journal: Aging Clinical and Experimental Research [Category] Coronavirus, MERS, SARS, [키워드] adherence affected affecting Ageing board Care carried change clinical guideline Collaborative effort Community COVID-19 COVID-19 pandemic Diagnosis disease European facilitated First wave groups hcp Health health information healthcare Healthcare professional identify IMPROVE Informal carers Innovation lack management medium NCD Noncommunicable Diseases organizations outcome partnership Patient Patient advocacy Patient care Patient empowerment patients Policy promote Public–private partnerships Regulation researchers Result risk factor SARS-CoV-2 Standardization Support Treatment Upjohn [DOI] 10.1007/s40520-021-01922-y PMC 바로가기 [Article Type] Original Article
HLA Does Not Impact on Short-Medium-Term Antibody Response to Preventive Anti-SARS-Cov-2 VaccineImmunology Published on 2021-07-272022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, SARS, [키워드] activated allele Analysis antibody titer level Antigen antigen-presenting cell APCS B cell response binding BNT162b2 mRNA COVID-19 vaccine BNT162b2 vaccine CD4 Cohort correlation COVID dependent on dose Efficacy evaluated first dose healthcare worker HLA HLA allelic variants HLA class II HLA-DQ antigens HLA-DR antigens HLA-DRB1 Impact medium persistence Pfizer-BioNTech predicted response SARS-CoV-2 spike glycoprotein Spike protein stimulated sustained T helper cell the antibody response the SARS-CoV-2 Vaccine vaccinee Vaccines Variability [DOI] 10.3389/fimmu.2021.734689 PMC 바로가기 [Article Type] Immunology
A Glimpse into the Diverse Cellular Immunity against SARS-CoV-2Article Published on 2021-07-272022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] acute respiratory syndrome Analysis anti-SARS-CoV-2 Anti-viral antigen presenting cell antigenic peptides antigens Cell Cellular immune response cellular immunity Combination coronavirus COVID-19 Critical death demonstrated dendritic cell Ex vivo FIVE Frequency functional immune Immunotherapy implication in healthy individual in healthy individuals individual infected with SARS-CoV-2 medium membrane mutated naïve nucleocapsid overlapping Patient peptide pool precursor presenting protease Protein Proteins Responder responders SARS-CoV-2 shown T-cell T-cell epitope T-cell immune response T-cell Response tested Vaccine Vaccine design variants Viral antigen wild-type virus [DOI] 10.3390/vaccines9080827 PMC 바로가기 [Article Type] Article
Country transition index based on hierarchical clustering to predict next COVID-19 wavesArticle Published on 2021-07-272022-10-29 Journal: Scientific Reports [Category] COVID-19, [키워드] addition affected approach center Cluster Clustering Computational science Computer science country COVID-19 dataset death disease Engineering group health system Hierarchical incrementally Infection Johns Hopkins University medium occur predict Science Scientific data Spread System Temporal analysis virus [DOI] 10.1038/s41598-021-94661-z PMC 바로가기 [Article Type] Article
Public fear of COVID-19 vaccines in Iraqi Kurdistan region: a cross-sectional studyResearch Published on 2021-07-272022-10-29 Journal: Middle East Current Psychiatry [Category] COVID-19, [키워드] AstraZeneca Blood COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines cross-sectional demographic characteristics determine Diseases effective Factor fear IMPROVE indicated Infection Iraqi Kurdistan Kurdistan Region of Iraq majority media medium Ministry of Health other variable participant Pfizer positive proportion Public public health crisis questionnaire reduce reported Result Seasonal influenza Side effect significant variables significantly Sinopharm Support vaccination Vaccine was related widespread [DOI] 10.1186/s43045-021-00126-4 PMC 바로가기 [Article Type] Research