mononuclear cell
[용어속성] Term
Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment
Research article
[키워드] Activation
alteration
changes in
compartment
Coronavirus disease 2019
COVID-19
determine
dysfunctional neutrophils
dysregulated immune response
elevated
emergency myelopoiesis
Evidence
form
Immune cell
immune profiling
individuals
inflammatory monocyte
interferon-stimulated gene
mass cytometry
mechanism
Mild
moderate
Monocytes
mononuclear cell
myeloid
myeloid cell
neutrophil
neutrophil count
Neutrophils
Occurrence
Pathogenesis
Patient
precursors
protective immunity
provide
Respiratory failure
respiratory tract infection
reveal
SARS-CoV-2
SARS-COV-2 infection
scRNA-seq
severe COVID-19
severe disease
single-cell proteomics
Single-cell RNA-sequencing
subset
systemic immune response
[DOI] 10.1016/j.cell.2020.08.001 [Article Type] Research article
[DOI] 10.1016/j.cell.2020.08.001 [Article Type] Research article
Immunologic Effects of Vitamin D on Human Health and Disease
Review
[키워드] 1,25-dihydroxyvitamin D
25-hydroxyvitamin D
active form
activity
adaptive immune system
administration
Autoimmune disorders
benefit
clinical trial
component
conducted
COVID-19
debatable
determine
diabetes
disease
disorders
Effect
Efficacy
endothelial
endothelial membrane stability
Evidence
Gene Expression
Health
healthy
Human
immune function
immune-related disease
Immunologic
immunomodulation
immunomodulatory
increased risk
individual
Infectious diseases
Inflammation
inter-individual
less
Lymphocytes
macrophages
maintain
membrane
metabolism
metabolite
Monocytes
mononuclear cell
multiple sclerosis
outcomes
Peripheral blood
phosphate
Regulation
respiratory infection
responsible
rheumatoid arthritis
Sepsis
serum 25-hydroxyvitamin D
shown
stability
Treatment
Tuberculosis
Type 1 diabetes
Vitamin D
Vitamin D supplementation
[DOI] 10.3390/nu12072097 PMC 바로가기 [Article Type] Review
[DOI] 10.3390/nu12072097 PMC 바로가기 [Article Type] Review
Some pathological observations on the naturally infected dromedary camels (Camelus dromedarius) with the Middle East respiratory syndrome coronavirus (MERS-CoV) in Saudi Arabia 2018–2019
Other
[키워드] accompanied
addition
affected
age
Camelus dromedarius
capillary
carried
Cell
Clinical sign
collected
Complete
conditions
desquamation
Dromedary camel
epithelial hyperplasia
examined
glomerular
immunohistochemistry
infected dromedary camel
infected dromedary camels
Infection
infiltration
interstitial
interstitial pneumonia
kidneys
knowledge
lamina propria
MERS-CoV
MERS-CoV infection
Middle East
mononuclear cell
much higher
natural infection
observation
pathological change
pathological changes
pathology
positive
Prevalence
Protein
ranged
Rapid
recent
renal
replaced
respiratory epithelium
respiratory syndrome coronavirus
respiratory tract
Result
RT-PCR
Saudi Arabia
selected
sensitivity
[DOI] 10.1080/01652176.2020.1781350 PMC 바로가기 [Article Type] Other
[DOI] 10.1080/01652176.2020.1781350 PMC 바로가기 [Article Type] Other
Impact of pantoprazole on absorption and disposition of hydroxychloroquine, a drug used in Corona Virus Disease-19 (Covid-19): A structured summary of a study protocol for a randomised controlled trial
Letter
[키워드] 1:1
Absorption
administration
All participant
anticipated
Area
assigned
AUC
C max
center
changes in
clinical
Concentration
control group
Corona
Course
COVID-19
CYP2D6
CYP3A4
dissemination
dose
drug
drug-drug interaction
element
enrolment
enzyme activity
Enzymes
EudraCT
Germany
HCQ
Hydroxychloroquine
Impact
inhibitor
investigator
Microdosing
Midazolam
mononuclear cell
not blinded
number
objective
Open-label
outcome
P450
Pantoprazole
parallel group
participant
Patient
PBMC
PBMCs
performed
Peripheral blood
Phase I
plasma
PPI
probe
protocol
randomisation list
randomised
randomised controlled trial
Randomized
receive
recruitment
Registered
registry
reported
Sample size
secondary
single dose
Standard
status
Study protocol
target cell
treated
treatment group
Trial
trial protocol
Two-arm
university
Volunteer
website
Whole blood
Yohimbine
[DOI] 10.1186/s13063-020-04476-y PMC 바로가기 [Article Type] Letter
[DOI] 10.1186/s13063-020-04476-y PMC 바로가기 [Article Type] Letter
Safety and efficacy assessment of allogeneic human dental pulp stem cells to treat patients with severe COVID-19: structured summary of a study protocol for a randomized controlled trial (Phase I / II)
중증 COVID-19 환자를 치료하기 위한 동종 인간 치수 줄기세포의 안전성 및 효능 평가: 무작위 대조 시험(I/II상)을 위한 연구 프로토콜의 구조화된 요약
Letter
[키워드] 1:1
Acidic
Adenovirus
Admission
AIDS
Alanine
alanine aminotransferase
albumin
alkaline phosphatase
Allogeneic
allogeneic human dental pulp stem cells
amyloid
Analysis
anion gap
Arm ratio
aspartate
Aspartate aminotransferase
average
B lymphocyte
basophils
Before menopause
Bilirubin
blind
blinded
Block randomization method
Blood
blood cell
Blood cells
blood pressure
Blood routine
C-reactive protein
calcium
carbon dioxide
Care
CAST
caused
Cell
cell suspension
change
chest X-ray
Child Pugh score
chlorine
cholesterol
cholinesterase
CLARITY
clinical
Clinical improvement
clinical trial
coded
Coefficient of variation
color
commenced
comparator
computer
Concentration
Consent
consent form
Continuous renal replacement therapy
control group
control groups
COVID-19
COVID-19; randomised controlled trial; protocol; human dental pulp stem cells; dental stem cell banking
COVID-2019
creatine
creatine kinase
creatinine
criteria
crystal
Cytokines
cytomegalovirus
cytomegalovirus CMV-IgG
cytomegalovirus CMV-IgM
Definition
dental pulp
dental pulp stem cells
description
detect
Diastolic blood pressure
direct bilirubin
discharge
disease
dissemination
distress
distribution
DPSCs
ECMO
Efficacy
element
enrolled
eosinophil
eosinophils
epithelial cells
estimated glomerular filtration rate
Estrogen
examined
excluded
exclusion criteria
experimental group
fat globules
Female patients
female subject
filtration rate
Final
flow cytometry
follow-up period
fungi
fungus
Globulin
glomerular filtration rate
Glucose
GRADE
Grade 1
grade 3
Grade 5
granulocyte
HBcAb
HBeAb
HBeAg
HBsAb
HBsAg
hDPSCs
Health Organization
heart rate
hematocrit
Hemodialysis
hemoglobin
hepatitis B
hepatitis C
HFNC
high density lipoprotein
hospitalised patient
Hospitalised patients
Hospitalization
Hospitalized
human DPSC
human DPSCs
hypersensitive C-reactive protein
hypoxia
Identifier
IgA
IgG
IgM
Il -10
IL-1
IL-1 β
IL-2
IL-4
IL-6
immune
Immunoglobulin
Immunological testing
improvement
IMV
inclusion criteria
Infectious disease
Influenza
Influenza virus
informed consent form
injection
Injections
intensive care
intensive care unit
Intravenous injection
Invasive mechanical ventilation
investigator
investigators
ITN-γ
ketone
ketone bodies
Kidney function
Kidney function tests
Killer cell
Laboratory
laboratory examinations
Lactate
lactate dehydrogenase
lactating women
leukocyte
leukocyte enzymes
lipoprotein
lipoprotein A
lipoprotein cholesterol
low density lipoprotein
lung lesion
lung lesions
lymphocyte
Lymphocytes
Macrophage
Magnesium
Medical care
Menopause
Monocytes
mononuclear cell
mononuclear cells
nasal
nasal catheter
natural killer
natural killer cell
neutrophil
Neutrophils
nitrite
NIV
Non-invasive
non-invasive mechanical ventilation
non-squamous epithelial cell
non-squamous epithelial cells
nucleic acid
nucleic acid test
number
objective
observation
occult
occult blood
Other
Other condition
outcome
oxygen
oxygen saturation
parallel group
parasites
partial pressure
participant
Patient
penetration
performed
Peripheral blood
Peritoneal dialysis
phase
phenotype
phosphatase
phosphorus
Placebo
placebo-controlled
Platelet
Platelet count
platelet distribution width
Platelets
Potassium
prealbumin
pregnancy test
pregnant
pressure
Primary outcome
Protein
protocol
random
randomisation
randomization
Randomized
Randomized controlled trial
receive
receiving
recruitment
red blood cell
red blood cells
renal
renal insufficiency
renal replacement therapy
Renmin Hospital
replacement therapy
required
researcher
respiratory
respiratory distress
respiratory infection
respiratory rate
Safety
Saline
saline solution
Sample size
SARS-CoV-2
secondary
Secondary outcomes
serious COVID-19
serum
serum amyloid
severe liver condition
severe pneumonia
single-cell analyses
sodium
specific gravity
Standard deviation
status
stem cell
study period
Study protocol
sugar
syphilis
Systolic blood pressure
T lymphocyte
Th1 cytokine
Th1 cytokines
Th2 cytokine
Th2 cytokines
therapeutic effect
therapeutic effects
time
TNF-a
Total
total bilirubin
Total cholesterol
total protein
traits
Transferrin
treat
Treatment
treatment for COVID-19
triacylglycerol
Trial
triple blinded
TTCI
Tuberculosis
Twenty participant
Twenty participants
university
urea
uric acid
Urine
urobilinogen
Variation
Version
vital signs
Volume
website
White blood cells
with HIV
within 6 months
women
World Health Organization
Wuhan
γ-glutamyl transferase
[DOI] 10.1186/s13063-020-04380-5 PMC 바로가기 [Article Type] Letter
[DOI] 10.1186/s13063-020-04380-5 PMC 바로가기 [Article Type] Letter
Expansion of myeloid-derived suppressor cells in patients with severe coronavirus disease (COVID-19)
Article
[키워드] Admission
Analysis
analyzed
Biomarker
Blood
Cell
circulating
Concentration
convalescent phase
COVID-19
COVID-19 disease
cytokine
Disease progression
disease severity
effector T cells
excessive immune response
expansion
expression
Frequency
functions
IL-6
immune
immune response
in vitro
increase in
Infectious diseases
inflammation marker
Inflammatory cytokine
longitudinal analysis
lymphopenia
massive
Mild
mild patients
mononuclear cell
mortality rate
Pathogenesis
Patient
performed
peripheral
plasma samples
profiles
reducing
reduction in
required
SARS-CoV-2
SARS-CoV-2-infected patients
serum
Severe case
severe coronavirus disease
severe COVID-19
severe COVID-19 disease
severe disease
Severe patient
suppressed
T cell
T cells
T-cell
T-cell activation
target
TGF-β
the patient
therapeutic approaches
to define
was obtained
was performed
was tested
[DOI] 10.1038/s41418-020-0572-6 PMC 바로가기 [Article Type] Article
[DOI] 10.1038/s41418-020-0572-6 PMC 바로가기 [Article Type] Article
A single-cell atlas of the peripheral immune response in patients with severe COVID-19
Research
[키워드] acute respiratory distress
appear
applied
caused
Cell
changes in
Coronavirus disease 2019
COVID-19
develop
disease
downregulation
global pandemic
healthy controls
heterogeneous
HLA class II
identify
immune
Immune cell
immunopathology
Inflammatory
Intensive
interferon-stimulated gene
lymphocyte
mechanical ventilation
monocyte
mononuclear cell
neutrophil
not express
pathophysiology
pathway
Patient
patients hospitalized
patients with COVID-19
PBMCs
Peripheral blood
peripheral immune response
phenotype
plasmablast
pro-inflammatory
pro-inflammatory cytokines
produced
protective immunity
Respiratory failure
SARS-CoV-2
scRNA-seq
Seven
severe COVID-19
severe disease
single-cell
Single-cell RNA sequencing
subset
syndrome
T cell
[DOI] 10.1038/s41591-020-0944-y [Article Type] Research
[DOI] 10.1038/s41591-020-0944-y [Article Type] Research
The inhibition of IL-2/IL-2R gives rise to CD8 + T cell and lymphocyte decrease through JAK1-STAT5 in critical patients with COVID-19 pneumonia
Article
[키워드] analyzed
B cells
CD8
controls
Critical
Critical case
cytokine
decrease
develop
elevated
enrolled
examined
expression
IL-2
immune response
information
Interleukins
investigated
JAK1
lymphocyte
molecular
mononuclear cell
Mortality
NK cell
Patient
patients
patients with COVID-19
PBMC
Peripheral blood
plasma
Pneumonia
Prognosis
qRT-PCR
Severe patient
signaling pathway
significantly
significantly lower
T cell
T cells
three groups
viral infection
with COVID-19
[DOI] 10.1038/s41419-020-2636-4 PMC 바로가기 [Article Type] Article
[DOI] 10.1038/s41419-020-2636-4 PMC 바로가기 [Article Type] Article