COVID‐19 patients in intensive care develop predominantly oliguric acute kidney injury중환자실의 코로나19 환자는 주로 핍뇨성 급성 신장 손상을 일으키고 있습니다.Observational Study Published on 2020-11-282022-09-10 Journal: Acta Anaesthesiologica Scandinavica [Category] SARS, 바이오마커, 임상, [키워드] Acute kidney injury Admission AKI albumin albuminuria analysed Biomarker Biomarkers Characteristics Chronic kidney disease COVID‐19 COVID‐19 patient COVID‐19 creatinine criteria develop evaluated filtration rate Final functional glomerular filtration rate ICU identify incidence initial intensive care KDIGO Kidney disease Kidney injury lead majority metalloproteinase microalbuminuria molecule Mortality Most patient Most patients neutrophil observational study occurred oliguria Patient patients plasma predict prospective observational study reduced renal replacement therapy renal tissue replacement therapy risk stage 2 syndrome therapy tissue damage Tissue Inhibitor urinary Urine Virus Disease Volume [DOI] 10.1111/aas.13746 PMC 바로가기 [Article Type] Observational Study
Clinical and pathological findings of SARS-CoV-2 infection and concurrent IgA nephropathy: a case reportCase Report Published on 2020-11-242022-10-28 Journal: BMC Nephrology [Category] COVID-19, [키워드] accumulating Acute kidney injury Case report Chinese clinical Clinical characteristics Collapsing Course COVID-19 COVID-19 in patient COVID-19 infection disease Evidence Follow-up glomerular glucocorticoid histological IgA IgA nephropathy indicated Injury kidney knowledge Macroscopic hematuria nephropathy outbreak pathological finding patients with COVID-19 Postmortem Prognosis receptor regimen remained renal renal abnormality renal function Renal involvement SARS-COV-2 infection the patient therapy treatment strategy Urine virus worsening [DOI] 10.1186/s12882-020-02163-3 PMC 바로가기 [Article Type] Case Report
Long-Term SARS-CoV-2 Infection Associated with Viral Dissemination in Different Body Fluids Including Bile in Two Patients with Acute CholecystitisCase Report Published on 2020-11-232022-10-29 Journal: International Review of Cell and Molecular Biology [Category] COVID-19, [키워드] assays bile biological sample Body body compartment body fluid Cholecystitis clinical manifestations collected contribute declined different time point digital PCR droplet digital PCR dropped highlight Including Infection nasopharyngeal Nasopharyngeal swab negativity onset of symptoms Patient patients plasma plasma sample provoke qRT-PCR quantification Rectal swabs respiratory sample RNA quantification RT-PCR SARS-CoV-2 SARS-CoV-2 positive patient SARS-CoV-2 RNA Symptom undetectable Urine Viral RNA [DOI] 10.3390/life10110302 PMC 바로가기 [Article Type] Case Report
Pilot Study: Long-Term Shedding of SARS-CoV-2 in Urine: A Threat for Dispersal in WastewaterPublic Health Published on 2020-11-232022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] complex Contamination COVID-19 global pandemic highlight kidney Nasopharyngeal swab Patient SARS CoV-2 SARS-CoV-2 SARS-CoV-2 epidemic SARS-CoV-2 RNA shedding threat Urine viral replication virus wastewater [DOI] 10.3389/fpubh.2020.569209 PMC 바로가기 [Article Type] Public Health
Open resource of clinical data from patients with pneumonia for the prediction of COVID-19 outcomes via deep learning딥 러닝을 통한 COVID-19 결과 예측을 위한 폐렴 환자의 임상 데이터 공개 리소스Article Published on 2020-11-182022-09-12 Journal: Nature biomedical engineering [Category] MERS, SARS, 진단, 치료기술, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Algorithm Analysis biochemical Biological techniques Blood cellular characteristic Chest computed tomography Clinical data clinical decision clinical feature clinical status Computational biology and bioinformatics Computed tomography coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pneumonia database Decision making deep learning Diagnosis diagnostic Diseases facilitate Health care independent laboratory-confirmed management Microbiology Mild morbidity morbidity and mortality outcome Patient patients patients with COVID-19 patients with pneumonia Pneumonia receiver receiver operating characteristic resource SARS-CoV-2 severe acute respiratory syndrome Coronavirus Severe case Urine utility validation cohort viral disease [DOI] 10.1038/s41551-020-00633-5 PMC 바로가기 [Article Type] Article
Immune suppression in the early stage of COVID-19 diseaseArticle Published on 2020-11-172022-10-04 Journal: Nature Communications [Category] SARS, 바이오마커, 임상, 치료기술, 치료법, [키워드] activated affected change clinical feature COVID-19 COVID-19 disease COVID-19 infection COVID-19 pathology COVID-19 patient driver early stage healthy donor identify immune response Immunosuppression immunosuppressive impairment in healthy individual Infectious disease Infectious diseases mechanism moderate molecular Non-COVID-19 occur outbreak Pathogenesis Patient patients patients with COVID-19 Pneumonia pneumonia case protein expression Proteomic analysis proteomics Quantitative resource Urine viral infection worldwide pandemic [DOI] 10.1038/s41467-020-19706-9 PMC 바로가기 [Article Type] Article
Celebrex Adjuvant Therapy on Coronavirus Disease 2019: An Experimental StudyPharmacology Published on 2020-11-062022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] adjusted adjuvant age Analysis Atherosclerosis available data Cancer celebrex Clinical data Clinical outcome clinical study complications Concentration condition conducted control group coronavirus disease COVID-19 COVID-19 case COVID-19 group COVID-19 patient COX-2 CT scans death rate diabetes discharged dosage dose effective Endpoint enrolled evaluated experimental group healthy individual hospital indicate individuals lab morbidity and mortality mortality rate pandemic PGE PGE2 positively correlated produced progression promote promoted prostaglandins reduce reduced Registered reported Seven severe COVID-19 severity significantly significantly higher Standard therapy suppress those with comorbidities Treatment Urine vital signs were measured [DOI] 10.3389/fphar.2020.561674 PMC 바로가기 [Article Type] Pharmacology
Necessity for detection of SARS-CoV-2 RNA in multiple types of specimens for the discharge of the patients with COVID-19Research Published on 2020-11-022022-10-30 Journal: Journal of Translational Medicine [Category] COVID-19, SARS, [키워드] alveolar anal swab Blood clinical symptom Corneal COVID-19 COVID-19 patients detect discharge discharge criteria discharged discharged patients dry cough enrolled Fever highest hospital Hospitalization Isolation MONITOR Multiple specimens Nasopharyngeal swab nasopharyngeal swab specimen nasopharynx oropharyngeal swab performed positive positive rate quantitative PCR Result RT-qPCR SARS-CoV-2 SARS-CoV-2 RNA secretion selected severe COVID-19 patients severe patients specimen specimens sputum Stool Swab the patient Urine with COVID-19 [DOI] 10.1186/s12967-020-02580-w PMC 바로가기 [Article Type] Research
Viable SARS-CoV-2 in various specimens from COVID-19 patientsComparative Study Published on 2020-11-012023-07-12 Journal: Clinical microbiology and infection : the official [Category] SARS, [키워드] Saliva SARS-CoV-2 shedding Stool Urine [DOI] 10.1016/j.cmi.2020.07.020 PMC 바로가기 [Article Type] Comparative Study
On the whereabouts of SARS-CoV-2 in the human body: A systematic review인체 내 SARS-CoV-2의 행방: 체계적인 검토Research Article Published on 2020-10-302022-08-13 Journal: PLoS Pathogens [Category] Biology and Life Sciences, COVID-19, MERS, SARS, [키워드] ACE2 ACE2 entry-receptor ACE2 receptor addition aligned Blood body fluid body fluids Brain breast milk caused cerebrospinal fluid complex interplay component concerning consequence Containment correlated COVID-19 patients detect infectious virus Diagnosis distribution entry receptor Evidence expressed expression data expression level expression levels focus foundation heart highlight Host human body human host human population human tissue human tissues Impact implicates the presence improve diagnostics Infectious virus information intestines kidneys knowledge lung Lungs male genital male genitals Mucus multiple organ multiple organs multiple tissue multiple tissues observé organotropism of SARS-CoV-2 pandemic pandemic virus performed pharynx Proteins provide researcher RNA Saliva SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 entry receptor SARS-CoV-2 pathogenesis SARS-CoV-2 patients Scientific community Semen Single Cell Spread Stool systematic review These data Trachea Treatment treatment of COVID-19 patients Urine vessels Viral viral presence viral shedding viral shedding in body fluids virus [DOI] 10.1371/journal.ppat.1009037 PMC 바로가기 [Article Type] Research Article