dosage – Page 24 – Communicable Diseases Research

Preliminary Experience With Low Molecular Weight Heparin Strategy in COVID-19 Patients

Pharmacology

Published on 2020-08-062022-10-31
Journal: Frontiers in Pharmacology [Category] COVID-19,

[키워드] 95% CI administration Admission all-cause mortality analyzed anticoagulation association clinical collected Consensus COVID- 19 COVID-19 COVID-19 patient demographic characteristics disease dosage DVT DVT prophylaxis Efficacy Evidence experience group heparin hospitalized COVID-19 patients hospitalized patients hypertension In-hospital in-hospital mortality incidence intermediate Laboratory Laboratory testing laboratory-confirmed LMWH LMWH (low molecular weight heparin) low molecular weight Mortality Older age pathophysiological Patient patients Prevalence Prophylactic Prophylaxis regimen remained Result significant difference significantly Strategy subgroups therapy thrombosis treated Treatment variable weight
[DOI] 10.3389/fphar.2020.01124 PMC 바로가기 [Article Type] Pharmacology

Research Progress of Chloroquine and Hydroxychloroquine on the COVID-19 and Their Potential Risks in Clinic Use

Pharmacology

Published on 2020-07-312022-10-31
Journal: Frontiers in Pharmacology [Category] COVID-19,

ENDOCRINOLOGY IN THE TIME OF COVID-19: Management of hyperthyroidism and hypothyroidism

Clinical Practice Guidance

Published on 2020-07-192022-10-31
Journal: European Journal of Endocrinology [Category] COVID-19, SARS,

COVID-19: Coagulopathy, Risk of Thrombosis, and the Rationale for Anticoagulation

Review

Published on 2020-07-172022-10-31
Journal: Clinical and applied thrombosis/hemostasis : offic [Category] COVID-19, MERS, SARS,

[키워드] Adapted addition Anticoagulant anticoagulation bleeding event can be used caused characterized coagulation parameter Coagulopathy complex COVID-19 cytokine d -dimer death decrease dosage dose effective Effects exaggerated inflammatory response Factor hematology IMPROVE incidence increase in Limited LMWH lung failure manifestation Microvascular thrombosis new coronavirus SARS-CoV-2 Novel coronavirus infection outcome parameter Patient patients patients with COVID-19 prognostic proportion rationale reduction in reported risk Sepsis severe COVID-19 manifestations severe COVID-19 patients shown Society Standard dose syndrome thrombosis
[DOI] 10.1177/1076029620938149 PMC 바로가기 [Article Type] Review

Efficacy of integrative Traditional Chinese and Western medicine for the treatment of patients infected with 2019 novel coronavirus (COVID-19) A protocol for systematic review and meta analysis

3800

Published on 2020-07-172022-10-30
Journal: Medicine [Category] COVID-19, SARS,

[키워드] 2019 novel coronavirus adverse event Analysis bias risk Biomarker case sery Case-control CBM changes in China Chinese clinical recovery CNKI Cochrane Library collected Computed tomography conducted controlled trials Coronavirus disease 2019 COVID-19 data extraction database dosage drug duration of fever effective Efficacy eligibility criteria Ethical approval Ethics evaluate Evidence incidence include Infrastructure integrative Traditional Chinese and Western medicine journal Laboratory literature Meta-analysis Mild moderate Mortality outcome Patient patients with COVID-19 peer-reviewed performed primary outcome measure progression protocol Quality of life Randomized controlled trials searched secondary sensitivity analysis service severity SinoMed Symptoms System systematic review Therapeutic approach therapeutic option Traditional Treatment Vaccine VIP Web of Science
[DOI] 10.1097/MD.0000000000020781 PMC 바로가기 [Article Type] 3800

Chinese Patent Medicines in the Treatment of Coronavirus Disease 2019 (COVID-19) in China

Pharmacology

Published on 2020-07-172022-10-31
Journal: Frontiers in Pharmacology [Category] COVID-19,

[키워드] addition Adverse reaction Anti-inflammatory Antiviral Characteristics China Chinese Chinese patent medicines Clinical application Clinical practice clinician CNKI collected Consensus COVID-19 CPM curative database disease dosage effective Elsevier Epidemic Frequency Google Scholar help identify immune regulation IMPROVE include information injection Lung injury mechanism Medicine Patent pharmacological action Precaution precautions promote Pulmonary function recommendation Research research findings Result shown therapeutic efficacy Traditional Traditional Chinese medicine treat Treatment Web of Science
[DOI] 10.3389/fphar.2020.01066 PMC 바로가기 [Article Type] Pharmacology

Polymorphic Forms of Valinomycin Investigated by NMR Crystallography

Article

Published on 2020-07-112022-10-29
Journal: International Journal of Molecular Sciences [Category] COVID-19, SARS,

[키워드] 2019-nCoV Affect analyzed Antiviral backbone computation conformational Crystallography described DFT dosage Effect expected Factor form forms GIPAW Interaction isotropic marker NMR NMR crystallography nuclei parameter PBE polymorph Polymorphic produced reported solid-state NMR stability valinomycin
[DOI] 10.3390/ijms21144907 PMC 바로가기 [Article Type] Article

BCG Against SARS-CoV-2: Second Youth of an Old Age Vaccine?

Pharmacology

Published on 2020-07-092022-10-31
Journal: Frontiers in Pharmacology [Category] COVID-19,

Concentration-dependent mortality of chloroquine in overdose

과다복용 시 클로로퀸의 농도 의존적 사망률

Research Article

Published on 2020-07-082022-10-31
Journal: eLife [Category] COVID-19, 말라리아,

[키워드] analysed Bayesian benefit Blood Brazil bypassing calculate calculated cause changes in Chloroquine Clinical efficacy Clinical practice clinical trial clinical trials Concentration conditions correlated COVID-19 COVID-19 infections Critical determine died dosage dose drug electrical estimate Evidence France French greater healthy volunteer High dose highest Human Hydroxychloroquine indicated Laboratory test lack malaria mathematical metabolised Mortality outcome overdose overdoses Patient Pharmacodynamics pharmacokinetics potential benefits predict predicted Predictive problem prolongation prospectively studied randomised recovery regimen Regression model resulting rheumatological risk of death Safe shown Side effect Side effects single doses Stage statistical model suffered survival tested threshold threshold concentration Toxicity treating COVID-19 Treatment treatment for COVID-19 Trial trials unlikely ventricular virus
[DOI] 10.7554/eLife.58631 PMC 바로가기 [Article Type] Research Article

Treatment of Severe COVID-19 with Tocilizumab Mitigates Cytokine Storm and Averts Mechanical Ventilation during Acute Respiratory Distress: A Case Report and Literature Review

Case Report

Published on 2020-07-032022-10-29
Journal: Tropical Medicine and Infectious Disease [Category] COVID-19,

[키워드] “cytokine storm” acute phase reactant acute phase reactants acute respiratory distress administer ARDS blood draws C-reactive protein caused chose clinical status COVID-19 cytokine cytokine release Cytokine release syndrome Cytokine storm D-dimer declining discharged disease distress dosage early treatment Evidence ferritin highlight Hydroxychloroquine ICU IL-6 IL-6 antagonist IL-6 inhibitor IL-6 inhibitors IL-6 receptor improvement Inflammation inhibitor intubation literature male management Mechanical mechanical ventilation Mortality oxygen support pandemic Patient patients patients with COVID-19 Prevent progression report reported respiratory Respiratory Coronavirus Respiratory disease respiratory symptom review SARS-CoV-2 serum severe COVID-19 storm Support syndrome the patient therapeutic Therapeutic benefit therapeutic strategy therapy Tocilizumab treat treated Treatment ventilator Wuhan, China
[DOI] 10.3390/tropicalmed5030112 PMC 바로가기 [Article Type] Case Report