Association between vaccine dose and risk of hepatitis B virus infection in Fujian Province, ChinaArticle Published on 2022-12-302023-06-11 Journal: Human vaccines & immunotherapeutics [Category] B형 간염, [키워드] dosage effective HBsAg hepatitis B vaccine Infection [DOI] 10.1080/21645515.2022.2153533 PMC 바로가기
An EUA for anakinra (Kineret) for COVID-19Article Published on 2022-12-122023-07-11 Journal: The Medical letter on drugs and therapeutics [Category] COVID19(2023년), [키워드] actemra adverse effects Anakinra Baricitinib Corticosteroids COVID-19 Dexamethasone dosage Drug interactions Efficacy lactation Olumiant Pregnancy Remdesivir Safety Tocilizumab Veklury
Broad and durable antibody response after vaccination with inactivated SARS-CoV-2 in individuals with a history of 2003 SARS-CoV infection2003년 SARS-CoV 감염 이력이 있는 개인에서 비활성화된 SARS-CoV-2 백신 접종 후 광범위하고 지속적인 항체 반응Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, [키워드] activity antibody Antibody Response Antigen Beta Delta dosage greater Heterologous heterologous immunization inactivated Inactivated vaccine individual naïve vaccinees neutralizing activities Neutralizing activity nucleoprotein omicron pseudovirus pseudoviruses RBD of SARS-CoV-2 receiving SARS-CoV SARS-CoV infection SARS-CoV-2 SARS-CoV-2 vaccine SARS-related coronaviruses second vaccination significantly higher suggested undetectable Universal vaccine vaccination Vaccine vaccinee vaccinees variant variants virus viruses were infected Wuhan [DOI] 10.1080/22221751.2022.2076613 PMC 바로가기 [Article Type] Article
Modeling studies on the role of vitamins B1 (thiamin), B3 (nicotinamide), B6 (pyridoxamine), and caffeine as potential leads for the drug design against COVID-19Article Published on 2022-11-072022-11-15 Journal: Journal of molecular modeling [Category] SARS, 신약개발, 치료제, [키워드] ACE-2 adopted Antiviral antiviral activity applied approach binding pocket binding site caffeine Cell Characteristics chemical property Compound COVID-19 COVID-19 pandemic docking domain dosage drug design effective evaluate function impair Interaction Invasion lack mechanism modeling molecular molecular dynamic simulations Neutral nicotinamide potential mechanism Protein pyridoxamine Safe SARS-CoV-2 selected Side effects Structural analysis Structure the SARS-CoV-2 the Spike thiamin Toxicity Vitamin Vitamin B. [DOI] 10.1007/s00894-022-05356-9 PMC 바로가기
Comparative efficacy and safety of pharmacological interventions for severe COVID-19 patients: An updated network meta-analysis of 48 randomized controlled trialsArticle Published on 2022-10-142022-11-15 Journal: Medicine [Category] meta-analysis, 진단, [키워드] Abstract ACM all-cause mortality Characteristics Colchicine Comparative convalescent plasma database decrease dosage effective Efficacy and safety hyperimmune Imatinib Immunoglobulin Intravenous immunoglobulin medication Methylprednisolone Network meta-analysis Older participant Patient pharmacological intervention Placebo Randomized controlled trial RCT RCTs Remdesivir Safe sarilumab searched severe COVID-19 Severe COVID-19 Infection severe COVID-19 patients suggested TEAE TEAEs treatment-emergent adverse event Trial [DOI] 10.1097/MD.0000000000030998 PMC 바로가기
Antioxidant, Anti-inflammatory, and Immunomodulatory Roles of Nonvitamin Antioxidants in Anti-SARS-CoV-2 TherapyArticle Published on 2022-10-132022-11-15 Journal: Journal of medicinal chemistry [Category] COVID19(2023년), SARS, 바이오마커, 치료제, [키워드] ACE2 receptor Activation activities alleviate Alleviating alveolar antioxidant antiviral role conformational change COVID-19 Cytokine storm Dipeptidyl peptidase 4 Direct dosage Endothelium favor furin Helicase host receptor hyperinflammation Illness severity immunogenic Inflammatory Inflammatory responses influences membranes Organ failure oxidative stress Papain-like protease pathology pathway protease reactive oxygen specy Receptor binding domain Replication risk RNA-dependent RNA polymerase role serine 2 the spike protein transmembrane vicious cycle viral spike protein [DOI] 10.1021/acs.jmedchem.2c01134 PMC 바로가기
Multiple sclerosis relapse after COVID-19 vaccination: A case report-based systematic reviewReview article Published on 2022-10-012022-10-05 Journal: Journal of clinical neuroscience : official journa [Category] 진단, [키워드] Abstract benefit booster dose Case report case sery concern COVID-19 COVID-19 vaccination COVID-19 vaccine disease dosage Efficacy eligible Exacerbation FIVE include Infection Multiple multiple sclerosis Patient patients Relapse reported Result risk searched second dose Side effects stimulate Symptom systematic review vaccination vaccination against COVID-19 Vaccine weakness Web of Science [DOI] 10.1016/j.jocn.2022.08.012 [Article Type] Review article
Evaluation of the efficacy of oral nano-silymarin formulation in hospitalized patients with COVID-19: A double-blind placebo-controlled clinical trialArticle Published on 2022-10-012022-11-15 Journal: Phytotherapy research : PTR [Category] COVID19(2023년), SARS, 치료제, [키워드] alanine aminotransferase Anti-viral Antiviral assigned baseline clinical trial Concomitant COVID-19 cytokine release Cytokine release syndrome Dexamethasone dosage double-blind Effect effective Effectiveness Efficacy Evidence follow-up period gel Hospitalization hospitalized patient Laboratory Laboratory parameters lack liver enzyme management outbreak pandemic participant Patient patients with COVID-19 placebo group placebo-controlled clinical trial receiving Remdesivir sample sizes SARS-CoV-2 significant difference significantly silymarin Symptom the placebo group therapeutic strategy Treatment treatment group two group viral disease were assessed [DOI] 10.1002/ptr.7537 PMC 바로가기
Molecular aspects of Omicron, vaccine development, and recombinant strain XE: A review오미크론의 분자적 측면, 백신 개발 및 재조합 균주 XE: 검토Review Published on 2022-10-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] ACE2 affinity antibody resistance B.1.1.529 booster Booster vaccine COVID-19 CRISPR decrease dosage Efficiency elicited epidemiological Evolution feature genomic global pandemic Infection Mutation omicron Omicron variant Prevalence rate of infection RBD region recombinant variants reduce Research research and development several variant several variants South Africa specific mutations spike region strain T-cell immunity Transmission utilization Vaccine Vaccine development Vaccines variant variant of COVID-19. variant-specific vaccine variant-specific vaccines virus with COVID-19 [DOI] 10.1002/jmv.27936 PMC 바로가기 [Article Type] Review
Clinical efficacy and in vitro neutralization capacity of monoclonal antibodies for severe acute respiratory syndrome coronavirus 2 delta and omicron variants중증급성호흡기증후군 코로나바이러스 2 델타 및 오미크론 변이체에 대한 단일클론항체의 임상적 효능 및 시험관내 중화능Article Published on 2022-10-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Casirivimab casirivimab/imdevimab clinical Concentration coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient decrease delta variant dosage Efficacy except for exhibit Hospital stay Imdevimab in vitro in vitro data in vivo Infection mAb mAbs monoclonal monoclonal antibodies monoclonal antibody neutralization Neutralization assay neutralization capacity neutralizing capacity neutralizing effect Omicron variant Patient patients treated performed provided receiving respiratory respiratory tract respiratory viral RNA SARS-CoV-2 SARS-CoV-2 delta SARS-CoV-2 RNA severe acute respiratory syndrome Coronavirus sotromivab Sotrovimab the SARS-CoV-2 therapeutic therapy treated variant Viral Virus neutralization virus neutralization assay virus neutralization assays [DOI] 10.1002/jmv.27916 PMC 바로가기 [Article Type] Article