Interstitial Lung Disease at High Resolution CT after SARS-CoV-2-Related Acute Respiratory Distress Syndrome According to Pulmonary Segmental AnatomyArticle Published on 2021-09-022022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] acute respiratory distress syndrome affected alteration ARDS average changes consecutive patient consolidation consolidations correlated Corticosteroid COVID-19 pneumonia CT finding CT scan demographic data described Diagnosis discharge distribution enrolled evaluate evaluated GGO GGOs Ground glass opacity high resolution computed tomography hospital discharge hospitalised HRCT Laboratory linear low-dose lower lobe lung median time Methylprednisolone Patient pulmonary pulmonary fibrosis pulmonary parenchyma Resolution respiratory Retrospective study Segmental Severe COVID-19 pneumonia spirometry survivor treated Volume [DOI] 10.3390/jcm10173985 PMC 바로가기 [Article Type] Article
A prospective, observational study to evaluate adverse drug reactions in patients with COVID-19 treated with remdesivir or hydroxychloroquine: a preliminary report렘데시비르 또는 하이드록시클로로퀸으로 치료받은 COVID-19 환자의 약물 부작용을 평가하기 위한 전향적 관찰 연구: 예비 보고서Observational Study Published on 2021-09-012022-09-11 Journal: European Journal of Hospital Pharmacy [Category] 임상, 치료제, [키워드] activity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 ADR ADRS Adverse drug reaction Adverse drug reactions adverse effect Adverse reactions authorisation baseline characteristics carried Causality clinical medicine Cohort cohorts coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 cumulative drug monitoring drug-related side effects and adverse reactions Efficacy EMA European Medicines Agency evaluate greater HCQ Health authority hospital hospitalised Hydroxychloroquine implementation incidence Local Observational cohort study outbreak participant Patient patients patients with COVID-19 pharmacovigilance pharmacy service preliminary report pressure public health real-world data regimen REM Remdesivir reported safety profile SARS-CoV-2 Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus Side effect Side effects study period Suspected System Therapeutic strategies treated Treatment treatment of COVID-19 [DOI] 10.1136/ejhpharm-2020-002613 PMC 바로가기 [Article Type] Observational Study
Increasing impact of COVID-19 on young adults: evidence from hospitalisations in Brazil젊은 성인에 대한 COVID-19의 영향 증가: 브라질 입원의 증거Article Published on 2021-09-012022-09-11 Journal: Public health [Category] SARS, 변종, [키워드] absence activity Adults age Age structure Analysis Brazil changed changes in concern conditions consequence control limit COVID-19 COVID-19 hospitalisation database dropped epidemiological Evidence examined exposure to financial support Government group hospitalisation hospitalisations hospitalised illness include Increasing individual Life expectancy limit longitudinal study magnitude Older pandemic Potential reached reduced Rejuvenation Rejuvenation trend. respiratory severe COVID-19 statistical Support surpassed transmissible variant vaccination Variation were used zone [DOI] 10.1016/j.puhe.2021.08.002 PMC 바로가기 [Article Type] Article
Genomic characteristics and clinical effect of the emergent SARS-CoV-2 B.1.1.7 lineage in London, UK: a whole-genome sequencing and hospital-based cohort study영국 런던의 신종 SARS-CoV-2 B.1.1.7 계통의 게놈 특성 및 임상 효과: 전체 게놈 시퀀싱 및 병원 기반 코호트 연구Article Published on 2021-09-012022-09-11 Journal: The Lancet. Infectious Diseases [Category] SARS, 변종, 치료기술, [키워드] adjusted age analysed Analysis association B.1.1.7 B.1.1.7 variant Characteristics Clinical effect Clinical severity Cohort cohort study collected college Comorbidities Council Cycle threshold value death defined emergence Engineering epitope Epitopes Ethnicity Evidence evidence of genomic genomic read hospital hospitalised identify Immunocompromised patient Immunocompromised patients inclusion criteria Infection Lineage London mass vaccination monoclonal antibodies Mutation mutations NHS NIHR no evidence of Ordinal Scale Patient patients PCR PCR cycle Poisson regression model Poisson regression models positive Positive test Prevalence raise Remdesivir SARS-CoV-2 SARS-CoV-2 B.1.1.7 Science sequenced Sequencing severe disease Sex specific mutation specific mutations Spike protein Symptom the spike protein the WHO threshold value Transmissibility Trust university vaccination variant variants Viral load Virological virus load VoC WHO ordinal scale whole-genome sequencing [DOI] 10.1016/S1473-3099(21)00170-5 PMC 바로가기 [Article Type] Article
Metformin use is associated with a reduced risk of mortality in patients with diabetes hospitalised for COVID-19Observational Study Published on 2021-09-012022-10-05 Journal: Diabetes & metabolism [Category] 임상, [키워드] addressed Admission Anti-inflammatory applied approach association complications COVID-19 death diabetes Diabetic feature French had more hospitalised immunosuppressive effects intubation Kaplan-Meier survival curve Logistic regression analysis lower risk Mechanical mechanical ventilation metformin Mortality mortality rate occurred Odds ratio outcome Patient patients with diabete Prevalence primary endpoint Primary outcome Probability Prognosis Propensity score reduced risk reported tracheal Treatment Type type 2 diabete type 2 diabetes Weighting [DOI] 10.1016/j.diabet.2020.101216 PMC 바로가기 [Article Type] Observational Study
Dapagliflozin in patients with cardiometabolic risk factors hospitalised with COVID-19 (DARE-19): a randomised, double-blind, placebo-controlled, phase 3 trialClinical Trial Published on 2021-09-012022-10-05 Journal: The lancet. Diabetes & endocrinology [Category] 임상, [키워드] 1:1 95% CI acute illness adverse event affecting assigned AstraZeneca atherosclerotic benefit cardiometabolic risk factor cardiovascular disease Chronic kidney disease clinical recovery clinical status COVID-19 Critically ill Dapagliflozin death dose double-blind dysregulated hazard ratio heart failure hospitalised hypertension inhibitor intention-to-treat kidney medication multiorgan failure occurred organ organ dysfunction outcome outcomes Patient patients treated patients with COVID-19 phase 3 trial Placebo placebo-controlled placebo-controlled trial Primary outcome Protective randomised Randomly Registered reported risk reduction Safety Serious Adverse Events statistically significant the placebo group Treatment type 2 diabetes were assessed were excluded with COVID-19 worsened [DOI] 10.1016/S2213-8587(21)00180-7 PMC 바로가기 [Article Type] Clinical Trial
Incidence of COVID-19 Hospitalisation in Patients with Systemic Lupus Erythematosus: A Nationwide Cohort Study from DenmarkArticle Published on 2021-08-272022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] 95% CI adjusted analysed case-control study cohort study Comorbidities COVID-19 Denmark Disease activity General population Glucocorticoid treatment Glucocorticoids hazard ratio hospitalisation hospitalisation with COVID-19 hospitalised Hydroxychloroquine hydroxychloroquine treatment immune functions incidence incidence of COVID-19 increased risk Infection investigated Lupus Patient person year SLE SLE patient SLE patients systemic systemic lupus erythematosus Treatment with COVID-19 [DOI] 10.3390/jcm10173842 PMC 바로가기 [Article Type] Article
Sex Differences and Predictors of In-Hospital Mortality among Patients with COVID-19: Results from the ANCOHVID Multicentre StudyArticle Published on 2021-08-262022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] active cancer addressed advanced age affected Analysis applied Autoimmune disease azithromycin treatment cardiovascular disease Clinical data cohort of patient collected conducted country COVID-19 COVID-19 pandemic CURB-65 score death difference Effect Factor hospital Hospital mortality hospitalised identify in-hospital mortality Kaplan–Meier method Lung disease median age men men and women Mortality multicentre multiple Cox regression outcome pandemic Patient predictor public health reached receiving Research Result risk factor Risk factors SARS-CoV-2 severe disease Sex Sex difference Spain stratified by sex survival was used with COVID-19 women [DOI] 10.3390/ijerph18179018 PMC 바로가기 [Article Type] Article
Incidence, Risk Factors and Impact on Clinical Outcomes of Bloodstream Infections in Patients Hospitalised with COVID-19: A Prospective Cohort StudyArticle Published on 2021-08-242022-10-27 Journal: Antibiotics [Category] COVID-19, [키워드] 95% CI Affect Analysis Antimicrobial stewardship bacterial super-infections bloodstream infection Bloodstream infections BSI clinical consecutive patient corticosteroid therapy corticosteroid treatment COVID-19 development Epidemiology Factor group Hospital stay hospitalised Impact IMV in-hospital mortality incidence increased risk independent IQR Italy Mortality Observational cohort study Patient Prospective risk risk factor significantly treated was performed with COVID-19 [DOI] 10.3390/antibiotics10091031 PMC 바로가기 [Article Type] Article
Prevalence of SARS-CoV-2 antibodies in Denmark: nationwide, population-based seroepidemiological study덴마크의 SARS-CoV-2 항체 유병률: 전국, 인구 기반 혈청 역학 연구Covid-19 Published on 2021-08-222022-09-12 Journal: European Journal of Epidemiology [Category] SARS, 진단, [키워드] analysed appear blood sample calculated children coronavirus disease COVID-19 COVID-19 serological testing Denmark diagnosed Epidemic estimate Evidence group hospitalised individual Infection MONITOR occur Older age pandemic parameters parent participant performed Population register positive progressed progression questionnaire RT-PCR SARS-CoV-2 SARS-CoV-2 antibody seroconverted seroepidemiological studies Seroprevalence seroprevalence survey Surveillance Symptom Symptoms tested total Ig Transmission [DOI] 10.1007/s10654-021-00796-8 PMC 바로가기 [Article Type] Covid-19