COVID-19 in Children: Respiratory Involvement and Some Differences With the AdultsPediatrics Published on 2021-03-292022-10-31 Journal: Frontiers in Pediatrics [Category] COVID-19, [키워드] acute respiratory distress ARDS can be used children complex mechanism coronavirus disease COVID-19 decrease develop Diagnosis difference explain Health heterogeneous Impact IMPROVE Interaction Involvement knowledge less majority mechanism morbidity MOST multidimensional Patient pediatric Pneumonia respiratory respiratory compromise respiratory involvement respiratory manifestation Respiratory system SARS-CoV-2 severe cases severity syndrome the disease Treatment [DOI] 10.3389/fped.2021.622240 PMC 바로가기 [Article Type] Pediatrics
The severity and atypical presentations of COVID-19 infection in pediatrics소아과에서 COVID-19 감염의 중증도 및 비전형적 표현Case Reports Published on 2021-03-252022-09-01 Journal: BMC Pediatrics [Category] SARS, 임상, 진단, 치료기술, [키워드] 2019-nCoV acute pancreatitis affected age Atypical Boy Chain Reaction children conducted confirmed case Contact COVID-19 COVID-19 infection COVID-19 patients COVID-19 severity D-dimer Deep venous thrombosis emergence family members fatigue Fever group headache hypoxia infected with COVID-19 Inflammatory International manifestation Manifestations manifested mechanical ventilation median MIS-C MOST multivariate regression analysis nucleic acid Observational cohort study Pancreatitis polymerase chain polymerase chain reaction public health emergency real-time reverse transcriptase Result reverse transcriptase Severe case severe cases severe COVID-19 Severe patient severe patients severity severity of COVID-19 Shock significant difference significant differences significantly higher syndrome thrombosis Venous thrombosis WHO [DOI] 10.1186/s12887-021-02614-2 PMC 바로가기 [Article Type] Case Reports
Severe urticarial rash as the initial symptom of COVID-19 infectionCOVID-19 감염의 초기 증상으로 심한 두드러기 발진Case Reports Published on 2021-03-252022-09-11 Journal: BMJ case reports [Category] SARS, 치료제, [키워드] affecting Antihistamine antiviral therapy COVID-19 COVID-19 infection Cutaneous cutaneous manifestation Cutaneous manifestations Dermatology described erythematous followed by hive hives include initial initial symptom lesions life maculopapular rash manifestation occur PCR test positive Quality of life Rash rashe reported role SARS-CoV-2 PCR test self-limiting Severe case severe cases Shortness of breath Symptom Symptoms therapy Vascular vesicular rash [DOI] 10.1136/bcr-2021-241793 PMC 바로가기 [Article Type] Case Reports
Evaluation of glycemic traits in susceptibility to COVID-19 risk: a Mendelian randomization studyResearch Article Published on 2021-03-242022-10-28 Journal: BMC Medicine [Category] COVID-19, SARS, [키워드] 95%CI Analysis applied association conducted confidence interval controls coronavirus disease COVID-19 COVID-19 case COVID-19 phenotype COVID-19 phenotypes diabetes estimate Evidence fasting glucose Genetic genetic instrument Genetic predisposition Genome Glucose glycated hemoglobin glycemic hemoglobin Hospitalized increase in initiative log mendelian randomization MR-Egger observational study predisposition Result risk risk of COVID-19 severe cases severe COVID-19 severity of COVID-19 supplementary material susceptibility type 2 diabete type 2 diabetes unlikely weighted median Weighting [DOI] 10.1186/s12916-021-01944-3 PMC 바로가기 [Article Type] Research Article
Current trends and geographical differences in therapeutic profile and outcomes of COVID-19 among pregnant women – a systematic review and meta-analysis임산부의 COVID-19 치료 프로파일 및 결과의 현재 동향 및 지리적 차이 - 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-03-242022-09-10 Journal: BMC Pregnancy and Childbirth [Category] SARS, 치료제, [키워드] administration adverse outcome adverse outcomes Adverse pregnancy outcomes Analysis analyzed Antibiotics Antiviral antivirals article Asian assessment average Case report case sery Cesarean section clinical care clinical outcomes coronavirus coronavirus disease COVID-19 cumulative current disease effective eligible European except for highest Hospital stay Hydroxychloroquine ICU admission immunosuppressants imperative IMPROVE lack Latin Maternal death mechanical ventilation meta-analyses Meta-analysis nine outcome outcomes oxygen oxygen support Oxygen therapy patients performed plasma Pregnancy pregnant women Preterm birth proportion proportions reported Result risk stratification severe cases supplementary material systematic review therapeutic Therapeutics therapy Treatment treatments for COVID-19 was performed with COVID-19 [DOI] 10.1186/s12884-021-03685-w PMC 바로가기 [Article Type] Meta-Analysis
Risk profiles of severe illness in children with COVID-19: a meta-analysis of individual patients Research Published on 2021-03-222022-10-05 Journal: Pediatric Research [Category] SARS, 바이오마커, [키워드] 95% confidence interval age age and sex Asymptomatic authors C-index Case report chest X-ray children children with COVID-19 Comorbidity conducted cough COVID-19 CRP data extraction develop diagnosed Dyspnea Evidence facilitate Factor FIVE handling identify Impact LDH literature Meta-analysis Odds ratio Patient potential risk profile programming reflected Result risk risk factor severe cases severe symptom severity significantly Stata tachypnea were used with COVID-19 [DOI] 10.1038/s41390-021-01429-2 [Article Type] Research
Umbilical cord blood-derived microglia-like cells to model COVID-19 exposureArticle Published on 2021-03-192022-10-29 Journal: Translational Psychiatry [Category] COVID-19, [키워드] approach Biomarker Brain brain development can be used Cell childhood children COVID-19 COVID-19 pandemic Critical cytokine cytokine production developmental fetal generate immune immune activation immune cells impacted in vivo inaccessible Inflammatory methodology microglia microglial Molecular neuroscience mononuclear cell mononuclear cells morbidity morphologically Neonatal Neonate Non-invasive Peripheral blood priming programming SARS-COV-2 infection severe cases stem cells Umbilical cord umbilical cord blood unique [DOI] 10.1038/s41398-021-01287-w PMC 바로가기 [Article Type] Article
Understanding the clinical and demographic characteristics of second coronavirus spike in 192 patients in Tehran, Iran: A retrospective study이란 테헤란 환자 192명에서 발생한 두 번째 코로나바이러스 급증의 임상 및 인구통계학적 특성 이해: 후향적 연구Research Article Published on 2021-03-192022-09-12 Journal: PLoS ONE [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affected age appear average betamethasone BMI Care Clinical characteristics Clusters condition conditions coronavirus coronavirus disease cough country COVID-19 death demographic demographic and clinical characteristics demographic characteristics disorder disorders drug Fever Health Hospitalization in some incidence investigated Iran IVIG lack logistic regression model Medical care Non-severe case non-severe cases pandemic Patient persistent cough presenting presenting symptom problem raised Retrospective study SARS-CoV-2 second wave severe acute respiratory syndrome Coronavirus Severe case severe cases severity statistical statistically suggested Symptom Tehran Transmission understanding [DOI] 10.1371/journal.pone.0246314 PMC 바로가기 [Article Type] Research Article
Back to basics in COVID‐19: Antigens and antibodies—Completing the puzzleCOVID-19의 기본으로 돌아가기: 항원과 항체—퍼즐 완성하기Review Published on 2021-03-182022-09-10 Journal: Journal of Cellular and Molecular Medicine [Category] SARS, 변종, 진단, [키워드] antibodies antibody antigens back battle cellular coronavirus disease Coronavirus disease 2019 counterattack COVID‐19 estimate Evolution Genetic homoeostasis immune memory immune response immune system Immunological memory Infection infectiousness information investigated knowledge lack memory cell Memory cells molecular Molecular diagnosis mutations outbreak Pandemia pathogen Patient persistence Prevalence protective effect Protective effects SARS‐CoV‐2 SARS‐CoV‐2 infection SARS‐CoV‐2 Severe case severe cases stages Task Force tested tests tissue repair treat viability Viral viral infection virus [DOI] 10.1111/jcmm.16462 PMC 바로가기 [Article Type] Review
Lack of association of baseline 25-hydroxyvitamin D levels with disease severity and mortality in Indian patients hospitalized for COVID-19Observational Study Published on 2021-03-182022-10-04 Journal: Scientific Reports [Category] 임상, 치료법, [키워드] 25-hydroxyvitamin D Admission association baseline Clinical improvement clinical outcomes Comorbidities conducted correlated correlation COVID-19 D-dimer disease severity dose ferritin Hospitalized hospitalized COVID-19 patients ICU admission immunomodulatory effect Infectious diseases Inflammatory marker inflammatory markers LDH median Mild Mortality not significantly different oral cholecalciferol outcome outcomes oxygen Oxygen requirement parathormone Patient patients patients hospitalized proportion PTH recruited serum Severe case severe cases severe disease significantly significantly higher the WHO treated VDD viral infection vitamin D deficiency with COVID-19 [DOI] 10.1038/s41598-021-85809-y PMC 바로가기 [Article Type] Observational Study